DK625986A - Azoniaspironortropanolestere samt deres fremstilling og anvendelse - Google Patents
Azoniaspironortropanolestere samt deres fremstilling og anvendelseInfo
- Publication number
- DK625986A DK625986A DK625986A DK625986A DK625986A DK 625986 A DK625986 A DK 625986A DK 625986 A DK625986 A DK 625986A DK 625986 A DK625986 A DK 625986A DK 625986 A DK625986 A DK 625986A
- Authority
- DK
- Denmark
- Prior art keywords
- pironor
- tropanol
- azonia
- esters
- preparation
- Prior art date
Links
- CYHOMWAPJJPNMW-JIGDXULJSA-N tropine Chemical class C1[C@@H](O)C[C@H]2CC[C@@H]1N2C CYHOMWAPJJPNMW-JIGDXULJSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
- C07D471/20—Spiro-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/22—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed systems contains four or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
- C07D498/20—Spiro-condensed systems
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19853546218 DE3546218A1 (de) | 1985-12-27 | 1985-12-27 | Azoniaspironortropanolester, verfahren zu deren herstellung und pharmazeutisches mittel |
| DE3546218 | 1985-12-27 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| DK625986D0 DK625986D0 (da) | 1986-12-23 |
| DK625986A true DK625986A (da) | 1987-06-28 |
| DK171042B1 DK171042B1 (da) | 1996-04-29 |
Family
ID=6289623
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK625986A DK171042B1 (da) | 1985-12-27 | 1986-12-23 | Fremgangsmåde til fremstilling af azoniaspironortropanolestere |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US4855422A (da) |
| JP (1) | JPH07110862B2 (da) |
| CS (1) | CS274287B2 (da) |
| DD (1) | DD255162A5 (da) |
| DE (1) | DE3546218A1 (da) |
| DK (1) | DK171042B1 (da) |
| ZA (1) | ZA869694B (da) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5610163A (en) * | 1989-09-16 | 1997-03-11 | Boehringer Ingelheim Gmbh | Esters of thienyl carboxylic acids and amino alcohols and their quaternization products |
| DE3931041C2 (de) | 1989-09-16 | 2000-04-06 | Boehringer Ingelheim Kg | Ester von Thienylcarbonsäuren mit Aminoalkoholen, ihre Quaternierungsprodukte, Verfahren zu ihrer Herstellung und diese enthaltende Arzneimittel |
| DE4108393A1 (de) * | 1991-03-15 | 1992-09-17 | Boehringer Ingelheim Kg | Neue ester bi- und tricyclischer aminoalkohole, ihre herstellung und ihre verwendung in arzneimitteln |
| US5770738A (en) * | 1992-03-05 | 1998-06-23 | Boehringer Ingelheim Kg | Esters of bi- and tricyclic amino alcohols, their preparation and their use in pharmaceutical compositions |
| DE59900129D1 (de) | 1999-02-20 | 2001-07-26 | Pfleger R Chem Fab | Verfahren zum Herstellen von endo-Nortropin unter Verwendung von 8-Benzyl-nortropan-3-on-perchlorat als Zwischenprodukt, sowie letzteres Salz selbst |
| US6706726B2 (en) * | 2000-10-14 | 2004-03-16 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Anticholinergics which may be used as medicaments as well as processes for preparing them |
| EP1881980B1 (en) * | 2005-05-02 | 2012-08-22 | Boehringer Ingelheim International GmbH | Novel crystalline forms of tiotropium bromide |
| AU2006259202B2 (en) * | 2005-06-15 | 2012-05-10 | Boehringer Ingelheim International Gmbh | Process for preparing tiotropium salts, tiotropium salts as such and pharmaceutical compositions thereof |
| WO2008101728A1 (de) | 2007-02-23 | 2008-08-28 | K.H.S. Pharma Holding Gmbh | Verfahren zur herstellung von azoniaspironortropinestern und von nortropan-3-on verbindungen |
| CN101759696B (zh) * | 2008-12-23 | 2012-02-29 | 扬子江药业集团有限公司 | 去甲托品醇的合成工艺改进 |
| JP6503338B2 (ja) | 2013-03-15 | 2019-04-17 | バイオマリン ファーマシューティカル インコーポレイテッド | Ｈｄａｃ阻害剤 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1194422B (de) * | 1963-03-05 | 1965-06-10 | Robert Pfleger Chem Fab Dr | Verfahren zur Herstellung von Azoniaspironortropanderivaten |
| US3480626A (en) * | 1967-05-18 | 1969-11-25 | Chem Fab Dr R Pfleger | Certain azoniaspironortropine derivatives |
| DE2003680A1 (de) * | 1970-01-28 | 1971-08-05 | Boehringer Sohn Ingelheim | Benzilsaeurederivate |
-
1985
- 1985-12-27 DE DE19853546218 patent/DE3546218A1/de active Granted
-
1986
- 1986-12-23 DK DK625986A patent/DK171042B1/da not_active IP Right Cessation
- 1986-12-23 DD DD86298351A patent/DD255162A5/de not_active IP Right Cessation
- 1986-12-23 US US06/945,488 patent/US4855422A/en not_active Expired - Fee Related
- 1986-12-26 JP JP61308972A patent/JPH07110862B2/ja not_active Expired - Lifetime
- 1986-12-27 CS CS988386A patent/CS274287B2/cs unknown
- 1986-12-29 ZA ZA869694A patent/ZA869694B/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DE3546218C2 (da) | 1993-07-22 |
| JPH07110862B2 (ja) | 1995-11-29 |
| JPS62215588A (ja) | 1987-09-22 |
| US4855422A (en) | 1989-08-08 |
| DD255162A5 (de) | 1988-03-23 |
| CS274287B2 (en) | 1991-04-11 |
| CS988386A2 (en) | 1990-08-14 |
| DE3546218A1 (de) | 1987-07-02 |
| DK625986D0 (da) | 1986-12-23 |
| DK171042B1 (da) | 1996-04-29 |
| ZA869694B (en) | 1987-08-26 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B1 | Patent granted (law 1993) | ||
| PBP | Patent lapsed |