DK5891D0 - Udgangsmaterialer til brug ved fremstilling af phenylsubstituerede 2-mercaptoimidazolderivater - Google Patents

Udgangsmaterialer til brug ved fremstilling af phenylsubstituerede 2-mercaptoimidazolderivater

Info

Publication number
DK5891D0
DK5891D0 DK005891A DK5891A DK5891D0 DK 5891 D0 DK5891 D0 DK 5891D0 DK 005891 A DK005891 A DK 005891A DK 5891 A DK5891 A DK 5891A DK 5891 D0 DK5891 D0 DK 5891D0
Authority
DK
Denmark
Prior art keywords
mercaptoimidazold
phenyl
derivatives
substituted
preparation
Prior art date
Application number
DK005891A
Other languages
English (en)
Other versions
DK5891A (da
Inventor
James S Frazee
Carl Kaiser
Lawrence Ivan Kruse
Original Assignee
Smithkline Beckman Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beckman Corp filed Critical Smithkline Beckman Corp
Publication of DK5891A publication Critical patent/DK5891A/da
Publication of DK5891D0 publication Critical patent/DK5891D0/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/84Sulfur atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/54Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C07C217/56Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by singly-bound oxygen atoms
    • C07C217/62Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by singly-bound oxygen atoms linked by carbon chains having at least three carbon atoms between the amino groups and the six-membered aromatic ring or the condensed ring system containing that ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/347Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups
    • C07C51/36Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups by hydrogenation of carbon-to-carbon unsaturated bonds
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/52Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen
    • C07C57/58Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen containing six-membered aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/52Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen
    • C07C57/58Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen containing six-membered aromatic rings
    • C07C57/60Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen containing six-membered aromatic rings having unsaturation outside the rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/64Acyl halides
    • C07C57/76Acyl halides containing halogen outside the carbonyl halide groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK005891A 1983-04-12 1991-01-11 Udgangsmaterialer til brug ved fremstilling af phenylsubstituerede 2-mercaptoimidazolderivater DK5891D0 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US48412283A 1983-04-12 1983-04-12
US59066584A 1984-03-19 1984-03-19

Publications (2)

Publication Number Publication Date
DK5891A DK5891A (da) 1991-01-11
DK5891D0 true DK5891D0 (da) 1991-01-11

Family

ID=27047873

Family Applications (2)

Application Number Title Priority Date Filing Date
DK190384A DK190384A (da) 1983-04-12 1984-04-12 Dopamin-beta-hydroxylaseinhibitorer
DK005891A DK5891D0 (da) 1983-04-12 1991-01-11 Udgangsmaterialer til brug ved fremstilling af phenylsubstituerede 2-mercaptoimidazolderivater

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DK190384A DK190384A (da) 1983-04-12 1984-04-12 Dopamin-beta-hydroxylaseinhibitorer

Country Status (10)

Country Link
EP (3) EP0308573A3 (da)
AU (2) AU576317B2 (da)
CA (1) CA1242205A (da)
DE (1) DE3483652D1 (da)
DK (2) DK190384A (da)
ES (2) ES8506284A1 (da)
GR (1) GR79919B (da)
IE (1) IE57200B1 (da)
MY (1) MY102519A (da)
PT (1) PT78388B (da)

Families Citing this family (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4992459A (en) * 1983-04-12 1991-02-12 Smithkline Beecham Corporation Dopamine-β-hydroxylase inhibitors
US4532331A (en) * 1983-04-12 1985-07-30 Smithkline Beckman Corporation 1-Benzyl-2-aminomethyl imidazole derivatives
PT78388B (en) * 1983-04-12 1986-09-15 Smithkline Beckman Corp Dopamine-beta-hydroxylase inhibitors
US4707488A (en) * 1985-02-11 1987-11-17 Smithkline Beckman Corporation Dopamine-β-hydroxylase inhibitors and use thereof
US4634711A (en) * 1985-08-02 1987-01-06 Smithkline Beckman Corporation Pyridylalkyl imidazole-2-thiols
US4873357A (en) * 1985-10-31 1989-10-10 Smithkline Beckman Corporation Trifluoro acetyl-cyano-aniline intermediates for dopamine-βhydroxylase inhibitors
US4719223A (en) * 1985-10-31 1988-01-12 Smithkline Beckman Corporation Imidazolethiol dopamine-beta-hydroxylase inhibitors
US4743613A (en) * 1986-04-08 1988-05-10 Smithkline Beckman Corporation Ester prodrugs of dopamine-β-hydroxylase, inhibitors, composition containing them, and method of using them to inhibit dopamine-β-hydroxylase activity
US5057613A (en) * 1986-05-06 1991-10-15 Merrell Dow Pharmaceuticals Novel thione dopamine beta hydroxylase inhibitors
IL82401A0 (en) * 1986-05-06 1987-11-30 Merrell Dow Pharma Dopamine beta hydroxy-lase inhibiting imidazole derivatives and pharmaceutical compositions containing them
IL82542A0 (en) * 1986-05-23 1987-11-30 Smithkline Beckman Corp Triazole derivatives,their preparation and pharmaceutical compositions containing them
US5138069A (en) * 1986-07-11 1992-08-11 E. I. Du Pont De Nemours And Company Angiotensin II receptor blocking imidazoles
NZ221427A (en) * 1986-08-18 1990-12-21 Smithkline Beckman Corp 2-mercaptoimidazole derivatives and pharmaceutical compositions
US4762850A (en) * 1987-03-24 1988-08-09 Smithkline Beckman Corporation Dopamine-beta-hydroxylase inhibitors
EP0285356A3 (en) * 1987-03-30 1989-05-31 Smithkline Beecham Corporation Dopamine-beta-hydroxylase inhibitors
JP2577222B2 (ja) * 1987-04-10 1997-01-29 興和株式会社 新規な置換アニリド誘導体
US4835154A (en) * 1987-06-01 1989-05-30 Smithkline Beckman Corporation 1-aralykyl-5-piperazinylmethyl-2-mercaptoimidazoles and 2-alkylthioimidazoles and their use as dopamine-βhydroxylase inhibitors
US4798843A (en) * 1987-07-09 1989-01-17 Smithkline Beckman Corporation 2-mercaproimidazole dopamine-β-hydroxylase inhibitors
US4935438A (en) * 1987-12-29 1990-06-19 Smithkline Beckman Corporation Dopamine-β-hydroxylase inhibitors
US4882348A (en) * 1987-12-29 1989-11-21 Smithkline Beckman Corporation 2-(aminoalkylthio)imidazoles as dopamine-β-hydroxylase inhibitors
US4876266A (en) * 1987-12-31 1989-10-24 Smithkline Beckman Corporation 1-aralkyl-2-mercaptoimidazolines as DBH inhibitors
WO1989006131A1 (en) * 1987-12-31 1989-07-13 Smithkline Beckman Corporation 1-aralkyl-1,2-dihydropyrimidine-2-thiones
US5210079A (en) * 1988-01-07 1993-05-11 E. I. Du Pont De Nemours And Company Treatment of chronic renal failure with imidazole angiotensin-II receptor antagonists
US4880804A (en) * 1988-01-07 1989-11-14 E. I. Du Pont De Nemours And Company Angiotensin II receptor blocking benzimidazoles
CA1338238C (en) 1988-01-07 1996-04-09 David John Carini Angiotensin ii receptor blocking imidazoles and combinations thereof with diuretics and nsaids
CA2002246A1 (en) * 1988-12-01 1990-06-01 Lawrence I. Kruse Dopamine-.beta.-hydroxylase inhibitors
CA2002247A1 (en) * 1988-12-01 1990-06-01 Lawrence I. Kruse Dopamine-.beta.-hydroxylase inhibitors
US5354867A (en) * 1988-12-06 1994-10-11 E. I. Du Pont De Nemours And Company Angiotensin II receptor blocking imidazoles
US4916129A (en) * 1989-01-19 1990-04-10 E. I. Du Pont De Nemours And Company Combination β-blocking/angiotensin II blocking antihypertensives
AU645022B2 (en) * 1989-06-30 1994-01-06 E.I. Du Pont De Nemours And Company Fused-ring aryl substituted imidazoles
US5073566A (en) * 1989-11-30 1991-12-17 Eli Lilly And Company Angiotensin ii antagonist 1,3-imidazoles and use thereas
GB9010366D0 (en) * 1990-05-09 1990-06-27 Smith Kline French Lab Medicaments
IL98319A (en) * 1990-07-05 1997-04-15 Roussel Uclaf Sulphurous derivatives of imidazole, their preparation process, and pharmaceutical compositions containing them
FR2664271B1 (fr) * 1990-07-05 1994-02-18 Roussel Uclaf Nouveaux derives soufres de l'imidazole, leur procede de preparation, les nouveaux intermediaires obtenus, leur application a titre de medicaments et les compositions pharmaceutiques les renfermant.
FR2675503B1 (fr) * 1991-04-19 1994-02-18 Roussel Uclaf Nouveaux derives soufres de l'imidazole, leur procede de preparation, les nouveaux intermediaires obtenus, leur application a titre de medicaments et les compositions pharmaceutiques les renfermant.
US5332820A (en) * 1991-05-20 1994-07-26 E. I. Du Pont De Nemours And Company Dibenzobicyclo(2.2.2) octane angiotensin II antagonists
US5401851A (en) * 1992-06-03 1995-03-28 Eli Lilly And Company Angiotensin II antagonists
US6828415B2 (en) 1993-02-19 2004-12-07 Zentaris Gmbh Oligopeptide lyophilisate, their preparation and use
DE19620408A1 (de) * 1996-05-21 1997-11-27 Bayer Ag Mercapto-imidazolyl-Derivate
IT1295405B1 (it) 1997-09-30 1999-05-12 Merck Sharp & Dohme Italia S P Uso di un antagonista recettoriale di angiotensina ii per la preparazione di farmaci per aumentare il tasso di sopravvivenza di
FR2928544A1 (fr) * 2008-03-17 2009-09-18 Oreal Utilisation d'inhibiteurs de la dopamine-beta hydroxylase pour la pigmentation capillaire.

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE825253C (de) * 1948-11-27 1951-12-17 Bayer Ag Verfahren zur Herstellung von unsymmetrischen disubstituierten Thioharnstoffen
SE345453B (da) * 1965-10-21 1972-05-29 Ciba Geigy Ag
GB1291524A (en) * 1969-06-27 1972-10-04 Abbott Lab N-dialkoxyalkyl substituted phenethylamine derivatives
US3767816A (en) * 1971-08-26 1973-10-23 Rohm & Haas Diuretic thioureas
BE788850A (fr) * 1972-09-15 1973-03-15 Hoffmann La Roche Derives d'acide benzoique
DE2259627A1 (de) * 1972-12-06 1974-06-12 Hoechst Ag Imidazolyl-(2)-thio-alkansaeureester und verfahren zu ihrer herstellung
DE2538231A1 (de) * 1975-08-28 1977-03-10 Dynamit Nobel Ag Verfahren zur herstellung von aminoacetaldehydacetalen
CA1147342A (en) * 1977-10-12 1983-05-31 Kazuo Imai Process of producing novel phenylethanolamine derivatives
FI803127L (fi) * 1979-10-03 1981-04-04 Glaxo Group Ltd Heterocykliska foereningar
PT78388B (en) * 1983-04-12 1986-09-15 Smithkline Beckman Corp Dopamine-beta-hydroxylase inhibitors
US4532331A (en) * 1983-04-12 1985-07-30 Smithkline Beckman Corporation 1-Benzyl-2-aminomethyl imidazole derivatives

Also Published As

Publication number Publication date
GR79919B (da) 1984-10-31
PT78388B (en) 1986-09-15
ES539563A0 (es) 1985-11-01
ES8601911A1 (es) 1985-11-01
MY102519A (en) 1992-07-31
DE3483652D1 (de) 1991-01-03
IE840876L (en) 1984-10-12
DK5891A (da) 1991-01-11
EP0212066A1 (en) 1987-03-04
ES531551A0 (es) 1985-07-01
EP0308573A2 (en) 1989-03-29
EP0125033A1 (en) 1984-11-14
AU2585388A (en) 1989-02-23
PT78388A (en) 1984-05-01
EP0308573A3 (en) 1990-03-21
IE57200B1 (en) 1992-06-03
DK190384A (da) 1984-10-13
CA1242205A (en) 1988-09-20
ES8506284A1 (es) 1985-07-01
DK190384D0 (da) 1984-04-12
AU576317B2 (en) 1988-08-25
EP0125033B1 (en) 1989-04-26
AU2672684A (en) 1984-10-18
EP0212066B1 (en) 1990-11-22
AU613984B2 (en) 1991-08-15

Similar Documents

Publication Publication Date Title
DK5891D0 (da) Udgangsmaterialer til brug ved fremstilling af phenylsubstituerede 2-mercaptoimidazolderivater
DK425583D0 (da) Fremgangsmade til fremstilling af 4'-demethyl-epipodophyllotoxin-beta-d-ethylidenglycocid og acylderivater deraf samt mellemprodukt til brug ved fremgangsmaden
FI820828L (fi) Anordning foer avkapning av en materialbana i en uppvindningsmaskin med en dubbel baervals
FI834057A0 (fi) Anordning foer ytbelaeggning av roerliga materialbanor
DK457384D0 (da) Anvendelse af ph-vaerdi-regulerende materialer
DK518884D0 (da) Belaegningsmaterialer
DK477585D0 (da) Siddeindretning til brug ved optagelse af roengtenbilleder
DK184588D0 (da) Mellemprodukter til brug ved fremstilling af 1alfa,25-dihydroxylerede vitamin d2-derivater
MX154113A (es) Mejoras en conjunto de portabroca cortadora
DK281789D0 (da) Fremgangsmaade til fremstilling af riboflavin i form af granulater
DK15390A (da) Cholestadienderivat som mellemprodukt til brug ved fremstillingen af homovitamin-d3-derivater
DK309382A (da) Overfladebehandling af plademateriale
DK223783D0 (da) Fremgangsmade til fremstilling af dihydropyridiner samt mellemprodukter til anvendelse ved fremgangsmaden
DK152817C (da) Bladfjeder af kompositmateriale samt fremgangsmaade til fremstilling af samme
DK148517C (da) Dyvel til brug ved samling af moebeldele
ES532030A0 (es) Procedimiento de preparacion de 20-ceto-delta 16-esteroides y nuevos compuestos intermedios formados en este procedimiento
DK541487D0 (da) Sammenfoejning af materialer
DK14383D0 (da) Fremgangsmade til fremstilling af oligosaccharider samt mellemprodukter til brug ved fremstillingen
DK9685D0 (da) Osteform til brug ved fremstilling af oste
DK560684D0 (da) Osteform til brug ved fremstilling af oste
DK494687D0 (da) Beslag til brug ved samling af maatter
ES500293A0 (es) Perfeccionamientos en la construccion de puentes modulares
DK160039C (da) Forbindelsen alfa-bromidaetylkarbonat og anvendelse af alfa-bromidaetylkarbonat ved fremstilling af aetoxykarbonyloxyaetylesteren af penicillin g
DK376484D0 (da) Kassette til brug ved stoebning af bjaelkelag
NO168175C (no) Utgangsmaterialer for anvendelse ved fremstilling av forbindelser med fungicid aktivitet

Legal Events

Date Code Title Description
AHB Application shelved due to non-payment