DK589175A - - Google Patents

Info

Publication number
DK589175A
DK589175A DK589175A DK589175A DK589175A DK 589175 A DK589175 A DK 589175A DK 589175 A DK589175 A DK 589175A DK 589175 A DK589175 A DK 589175A DK 589175 A DK589175 A DK 589175A
Authority
DK
Denmark
Application number
DK589175A
Other versions
DK137751C (da
DK137751B (da
Inventor
W J Welstead
Original Assignee
Robins Co A H
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Robins Co A H filed Critical Robins Co A H
Publication of DK589175A publication Critical patent/DK589175A/da
Publication of DK137751B publication Critical patent/DK137751B/da
Application granted granted Critical
Publication of DK137751C publication Critical patent/DK137751C/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/08Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/06Antiarrhythmics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/06Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with radicals, containing only hydrogen and carbon atoms, attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
DK589175AA 1974-12-26 1975-12-23 Analogifremgangsmåde til fremstilling af alfa,alfa-diphenyl-alfa-(1-isopropyl-3-pyrrolidinyl)acetamid. DK137751B (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/536,708 US4002766A (en) 1974-12-26 1974-12-26 Antiarrhythmia methods

Publications (3)

Publication Number Publication Date
DK589175A true DK589175A (da) 1976-06-27
DK137751B DK137751B (da) 1978-05-01
DK137751C DK137751C (da) 1978-10-09

Family

ID=24139598

Family Applications (1)

Application Number Title Priority Date Filing Date
DK589175AA DK137751B (da) 1974-12-26 1975-12-23 Analogifremgangsmåde til fremstilling af alfa,alfa-diphenyl-alfa-(1-isopropyl-3-pyrrolidinyl)acetamid.

Country Status (18)

Country Link
US (1) US4002766A (da)
JP (1) JPS5191255A (da)
AU (1) AU498763B2 (da)
BE (1) BE836974A (da)
CA (1) CA1055396A (da)
CH (1) CH619932A5 (da)
DE (1) DE2558501A1 (da)
DK (1) DK137751B (da)
ES (1) ES443846A1 (da)
FI (1) FI753607A (da)
FR (1) FR2295745A1 (da)
GB (1) GB1535770A (da)
IE (1) IE43901B1 (da)
NL (1) NL185620C (da)
NO (1) NO754377L (da)
PH (1) PH13483A (da)
SE (1) SE428126B (da)
ZA (1) ZA757974B (da)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4133881A (en) * 1977-04-27 1979-01-09 A. H. Robins Company, Incorporated Azetidinyl acetonitrile and acetamide antiarrhythmia compositions and methods
US4242261A (en) * 1979-07-19 1980-12-30 A. H. Robins Company, Inc. Production of methylene-cycloamines
US4260606A (en) * 1979-07-19 1981-04-07 A. H. Robins Company, Inc. 3-Methyleneazetidine derivatives
US4594343A (en) * 1984-10-19 1986-06-10 Shanklin Jr James R 1-[(aminoalkyl and aminoalkylamino)carbonyl and thiocarbonyl]-α,α-diarylpyrrolidine, piperidine and homopiperidineacetamides and acetonitriles
IL76583A (en) * 1984-10-19 1988-08-31 Robins Co Inc A H 1-(aminoalkyl)-alpha'alpha-diaryl pyrrolidinyl,piperidino and homopiperidino acetamides and acetonitriles and pharmaceutical compositions containing them
US4810703A (en) * 1984-10-19 1989-03-07 A. H. Robins Company, Incorporated 1-((aminoalkyl and aminoalkylamino)carbonyl and thiocarbonyl)-alpha, alpha-diarylpyrrolidine, piperidine and homopiperidineacetamides and acetonitriles
US4812452A (en) * 1984-10-19 1989-03-14 A. H. Robins Company, Incorporated 1-((aminoalkyl and aminoalkylamino) carbonyl and thiocarbonyl)-α,α-diarylpyrrolidine, piperidine and homopiperidineacetamides and acetonitriles
US4812451A (en) * 1984-10-19 1989-03-14 A. H. Robins Company, Incorporated 1-(aminoalkyl and aminoalkylamino)carbonyl and thiocarbonyl)-α,.alpha.
GB8825505D0 (en) * 1988-11-01 1988-12-07 Pfizer Ltd Therapeutic agents
US5932594A (en) * 1988-11-01 1999-08-03 Pfizer, Inc. Muscarinic receptor antagonists
GB8906166D0 (en) * 1989-03-17 1989-05-04 Pfizer Ltd Therapeutic agents
US5233053A (en) * 1989-03-17 1993-08-03 Pfizer Inc. Pyrrolidine derivatives
US6693202B1 (en) 1999-02-16 2004-02-17 Theravance, Inc. Muscarinic receptor antagonists
TWI295669B (en) * 2002-10-30 2008-04-11 Theravance Inc Substituted 4-amino-1-(pyridylmethyl) piperidine and related compounds
EP1615881A2 (en) * 2003-04-01 2006-01-18 Theravance, Inc. Diarylmethyl and related compounds having beta2 adrenergic receptor agonist and muscarinic receptor antagonist activity
TW200510298A (en) * 2003-06-13 2005-03-16 Theravance Inc Substituted pyrrolidine and related compounds
WO2005007645A1 (en) * 2003-07-11 2005-01-27 Theravance, Inc. Substituted 4-amino-1-benzylpiperidine compounds
WO2005087763A1 (en) * 2004-03-11 2005-09-22 Theravance, Inc. Diphenylmethyl compounds useful as muscarinic receptor antagonists
WO2005087722A1 (en) * 2004-03-11 2005-09-22 Theravance, Inc. Diphenylmethyl compounds useful as muscarinic receptor antagonists
TW200540154A (en) * 2004-06-10 2005-12-16 Theravance Inc Crystalline form of a substituted pyrrolidine compound
US20070197630A1 (en) * 2005-12-27 2007-08-23 Valeriano Merli Pure darifenacin hydrobromide substantially free of oxidized darifenacin and salts thereof and processes for the preparation thereof
ES2554646T3 (es) * 2007-02-23 2015-12-22 Theravance Biopharma R&D Ip, Llc Compuestos de difenilmetilo de amonio cuaternario, de utilidad como antagonistas de receptores muscarínicos
EP2146957B1 (en) 2007-04-24 2013-06-12 Theravance, Inc. Quaternary ammonium compounds useful as muscarinic receptor antagonists
WO2012166909A1 (en) * 2011-06-03 2012-12-06 Galleon Pharmaceuticals, Inc. Compositions and methods for treating breathing control disorders or diseases

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3192210A (en) * 1961-12-04 1965-06-29 Robins Co Inc A H 4-(omega-substituted alkyl)-3, 3-disubstituted-1-substituted-2-pyrrolidinones and 4-(omega-substituted alkyl)-3, 3-disubstituted-1-substituted-2-thionpyrrolidinones
NL6606516A (da) * 1965-05-17 1966-11-18
US3878217A (en) * 1972-01-28 1975-04-15 Richardson Merrell Inc Alpha-aryl-4-substituted piperidinoalkanol derivatives

Also Published As

Publication number Publication date
FR2295745B1 (da) 1980-06-27
AU498763B2 (en) 1979-03-22
DK137751C (da) 1978-10-09
NL185620B (nl) 1990-01-02
CA1055396A (en) 1979-05-29
DE2558501A1 (de) 1976-07-08
PH13483A (en) 1980-05-21
NO754377L (da) 1976-06-29
FR2295745A1 (fr) 1976-07-23
ZA757974B (en) 1976-12-29
DK137751B (da) 1978-05-01
JPS612658B2 (da) 1986-01-27
NL185620C (nl) 1990-06-01
AU8754975A (en) 1977-06-23
SE428126B (sv) 1983-06-06
JPS5191255A (en) 1976-08-10
GB1535770A (en) 1978-12-13
ES443846A1 (es) 1977-07-16
FI753607A (da) 1976-06-27
US4002766A (en) 1977-01-11
IE43901L (en) 1976-06-26
IE43901B1 (en) 1981-07-01
DE2558501C2 (da) 1987-07-16
SE7514375L (sv) 1976-06-28
NL7515071A (nl) 1976-06-29
BE836974A (fr) 1976-04-16
CH619932A5 (da) 1980-10-31

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Legal Events

Date Code Title Description
PBP Patent lapsed