DK581685A - Transderimalt system for timolol-indgift - Google Patents

Transderimalt system for timolol-indgift Download PDF

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Publication number
DK581685A
DK581685A DK581685A DK581685A DK581685A DK 581685 A DK581685 A DK 581685A DK 581685 A DK581685 A DK 581685A DK 581685 A DK581685 A DK 581685A DK 581685 A DK581685 A DK 581685A
Authority
DK
Denmark
Prior art keywords
timolol
transderimal
administration
drug
irritation
Prior art date
Application number
DK581685A
Other languages
English (en)
Other versions
DK581685D0 (da
Inventor
J V Bondi
E M Cohen
A E Loper
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of DK581685D0 publication Critical patent/DK581685D0/da
Publication of DK581685A publication Critical patent/DK581685A/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7084—Transdermal patches having a drug layer or reservoir, and one or more separate drug-free skin-adhesive layers, e.g. between drug reservoir and skin, or surrounding the drug reservoir; Liquid-filled reservoir patches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
DK581685A 1984-12-17 1985-12-16 Transderimalt system for timolol-indgift DK581685A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/682,447 US4752478A (en) 1984-12-17 1984-12-17 Transdermal system for timolol

Publications (2)

Publication Number Publication Date
DK581685D0 DK581685D0 (da) 1985-12-16
DK581685A true DK581685A (da) 1986-06-18

Family

ID=24739746

Family Applications (1)

Application Number Title Priority Date Filing Date
DK581685A DK581685A (da) 1984-12-17 1985-12-16 Transderimalt system for timolol-indgift

Country Status (8)

Country Link
US (1) US4752478A (da)
EP (1) EP0186071B1 (da)
JP (1) JPH0684304B2 (da)
AT (1) ATE69720T1 (da)
CA (1) CA1261267A (da)
DE (1) DE3584766D1 (da)
DK (1) DK581685A (da)
ES (1) ES8702153A1 (da)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4797284A (en) * 1986-03-12 1989-01-10 Merck & Co., Inc. Transdermal drug delivery system
US4954343A (en) * 1986-03-29 1990-09-04 Nitto Electric Industrial Co., Ltd. Dermal pharmaceutical preparations
US4938759A (en) * 1986-09-02 1990-07-03 Alza Corporation Transdermal delivery device having a rate controlling adhesive
US4956181A (en) * 1987-05-08 1990-09-11 Eastman Kodak Nitrate therapy for angina pectoris
GB8804164D0 (en) * 1988-02-23 1988-03-23 Tucker J M Bandage for administering physiologically active compound
JPH02149514A (ja) * 1988-04-06 1990-06-08 Nitto Denko Corp 医薬部材
FI82240C (fi) * 1988-10-20 1991-02-11 Huhtamaeki Oy Foerfarande foer framstaellning av farmakologiskt vaerdefullt s-timolol-hemihydrat.
US5508038A (en) * 1990-04-16 1996-04-16 Alza Corporation Polyisobutylene adhesives for transdermal devices
US5484604A (en) * 1990-07-21 1996-01-16 Chatfield Pharmaceuticals Limited Cross-linked alginate transdermal medicine delivery devices
US5246706A (en) * 1991-07-19 1993-09-21 Cygnus Therapeutic Systems Device for administering bimakalim transdermally
ATE154513T1 (de) * 1992-07-08 1997-07-15 Leiras Oy Augenarzneimittel enthaltend timolol hemihydrat
DE4224325C1 (de) * 1992-07-23 1994-02-10 Sanol Arznei Schwarz Gmbh Wirkstoffpflaster für niedrigschmelzende und/oder flüchtige Wirkstoffe und Verfahren zu seiner Herstellung
WO1994010986A1 (en) * 1992-11-09 1994-05-26 Pharmetrix Corporation Transdermal delivery of ketorolac
DE4400769C2 (de) * 1994-01-13 1996-07-18 Lohmann Therapie Syst Lts Verfahren und Vorrichtung zur Herstellung einer flächigen Darreichungsform mit einer Arzneimittelwirkstoffe enthaltenden Zubereitung
GB9711032D0 (en) * 1997-05-30 1997-07-23 Johnson Matthey Plc Compound as a stimulant for the central nervous system
DK1293210T3 (da) * 2001-05-23 2004-03-15 Pantarhei Bioscience Bv Midler og fremgangsmåde til hormonal prævention
CA2448271A1 (en) * 2001-05-23 2002-11-28 Panterhei Bioscience B.V. Means and method for hormonal contraception
US20040198707A1 (en) * 2001-05-23 2004-10-07 Agatha Antonia Magdalena Van Beek Means and method for hormonal contraception
NZ533242A (en) 2001-12-05 2007-11-30 Duramed Pharmaceuticals Inc Oral extended regime contraceptive package
BRPI0412493A (pt) * 2003-07-16 2006-10-17 Duramed Pharmaceuticals Inc métodos de tratamento hormonal utilizando regimes contraceptivos com administração contìnua de estrogênio
JP2008500340A (ja) * 2004-05-26 2008-01-10 ワイス 月経前不機嫌性障害の処置のための組成物および方法
US20070111975A1 (en) * 2004-10-07 2007-05-17 Duramed Pharmaceuticals, Inc. Methods of Hormonal Treatment Utilizing Ascending-Dose Extended Cycle Regimens
TW200726473A (en) * 2005-06-28 2007-07-16 Wyeth Corp Compositions and methods for treatment of cycle-related symptoms
EP1965776A1 (en) * 2005-12-08 2008-09-10 Fertin Pharma Low flexural strength transdermal tobacco alkaloid patch
FR2950802B1 (fr) 2009-10-02 2012-02-03 Sartorius Stedim Biotech Sa Elaboration et/ou conservation d'un produit biopharmaceutique.
DE102010002558A1 (de) 2009-11-20 2011-06-01 Symrise Ag Verwendung physiologischer Kühlwirkstoffe und Mittel enthaltend solche Wirkstoffe
EP2394703B1 (de) 2010-06-14 2015-12-23 Symrise AG Kühlmischungen mit verstärkter Kühlwirkung von 5-Methyl-2-(propan-2-yl)cyclohexyl-N-ethyloxamat
US9029415B2 (en) 2010-06-14 2015-05-12 Symrise Ag Cooling mixtures with an enhanced cooling effect of 5-methyl-2-(propane-2-yl)cyclohexyl-N-ethyloxamate
WO2013041621A1 (de) 2011-09-20 2013-03-28 Basf Se Niedermolekulare modulatoren des kälte-menthol-rezeptors trpm8 und deren verwendung
CN109922796B (zh) 2016-06-23 2023-04-07 考里安有限责任公司 具有亲水和疏水域的粘合剂基质和治疗剂
KR102508993B1 (ko) * 2016-07-27 2023-03-10 코리움, 인크. 메만틴 경피 송달 시스템
EP3675809B1 (de) 2017-08-31 2023-09-27 Basf Se Verwendung physiologischer kühlwirkstoffe und mittel enthaltend solche wirkstoffe

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3598122A (en) * 1969-04-01 1971-08-10 Alza Corp Bandage for administering drugs
US3797494A (en) * 1969-04-01 1974-03-19 Alza Corp Bandage for the administration of drug by controlled metering through microporous materials
US4031894A (en) * 1975-12-08 1977-06-28 Alza Corporation Bandage for transdermally administering scopolamine to prevent nausea
US4060084A (en) * 1976-09-07 1977-11-29 Alza Corporation Method and therapeutic system for providing chemotherapy transdermally
US4286592A (en) * 1980-02-04 1981-09-01 Alza Corporation Therapeutic system for administering drugs to the skin
JPS56133381A (en) * 1980-03-25 1981-10-19 Nippon Kayaku Co Ltd Pressure-sensitive adhesive tape or sheet containing nitroglycerin
JPS57116011A (en) * 1981-01-08 1982-07-19 Nitto Electric Ind Co Ltd Pharmaceutical preparation
US4428883A (en) * 1981-03-06 1984-01-31 The University Of Kentucky Research Foundation Novel method of administering β-blockers and novel dosage forms containing same
US4560553A (en) * 1981-07-07 1985-12-24 Merck & Co., Inc. Use of eucalyptol for enhancing skin permeation of bio-affecting agents
US4440777A (en) * 1981-07-07 1984-04-03 Merck & Co., Inc. Use of eucalyptol for enhancing skin permeation of bio-affecting agents
JPS58134019A (ja) * 1982-02-05 1983-08-10 Ono Pharmaceut Co Ltd プロスタグランジン含有持続放出型三層状フイルム製剤及びその製造方法
US4559222A (en) * 1983-05-04 1985-12-17 Alza Corporation Matrix composition for transdermal therapeutic system
US4474751A (en) * 1983-05-16 1984-10-02 Merck & Co., Inc. Ophthalmic drug delivery system utilizing thermosetting gels
US4474753A (en) * 1983-05-16 1984-10-02 Merck & Co., Inc. Topical drug delivery system utilizing thermosetting gels
US4478822A (en) * 1983-05-16 1984-10-23 Merck & Co., Inc. Drug delivery system utilizing thermosetting gels
US4474752A (en) * 1983-05-16 1984-10-02 Merck & Co., Inc. Drug delivery system utilizing thermosetting gels
DE3319469A1 (de) * 1983-05-28 1984-11-29 Akzo Gmbh, 5600 Wuppertal System zur transdermalen applikation von pharmakotherapeutisch wirksamen substanzen
DE3586713T2 (de) * 1984-11-15 1993-05-13 Hercon Lab Vorrichtung zur kontrollierten abgabe von arzneimittelwirkstoffen.

Also Published As

Publication number Publication date
EP0186071A2 (en) 1986-07-02
JPH0684304B2 (ja) 1994-10-26
DE3584766D1 (de) 1992-01-09
ATE69720T1 (de) 1991-12-15
EP0186071B1 (en) 1991-11-27
US4752478A (en) 1988-06-21
ES550011A0 (es) 1987-01-01
DK581685D0 (da) 1985-12-16
JPS61145113A (ja) 1986-07-02
CA1261267A (en) 1989-09-26
ES8702153A1 (es) 1987-01-01
EP0186071A3 (en) 1988-09-14

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Legal Events

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AHS Application shelved for other reasons than non-payment