DK579089A - Renin-inhiberende urinstofderivater af dipeptider, deres fremstilling og anvendelse - Google Patents

Renin-inhiberende urinstofderivater af dipeptider, deres fremstilling og anvendelse

Info

Publication number
DK579089A
DK579089A DK579089A DK579089A DK579089A DK 579089 A DK579089 A DK 579089A DK 579089 A DK579089 A DK 579089A DK 579089 A DK579089 A DK 579089A DK 579089 A DK579089 A DK 579089A
Authority
DK
Denmark
Prior art keywords
inhibitive
dipeptides
pure
preparation
urinary
Prior art date
Application number
DK579089A
Other languages
Danish (da)
English (en)
Other versions
DK579089D0 (da
Inventor
Wolfgang Rueger
Hansjoerg Urbach
Dieter Ruppert
Bernward Schoelkens
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of DK579089D0 publication Critical patent/DK579089D0/da
Publication of DK579089A publication Critical patent/DK579089A/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06078—Dipeptides with the first amino acid being neutral and aromatic or cycloaliphatic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06139—Dipeptides with the first amino acid being heterocyclic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK579089A 1988-11-19 1989-11-17 Renin-inhiberende urinstofderivater af dipeptider, deres fremstilling og anvendelse DK579089A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3839126A DE3839126A1 (de) 1988-11-19 1988-11-19 Renin-hemmende harnstoffderivate von dipeptiden, verfahren zu deren herstellung, diese enthaltende mittel und ihre verwendung

Publications (2)

Publication Number Publication Date
DK579089D0 DK579089D0 (da) 1989-11-17
DK579089A true DK579089A (da) 1990-05-20

Family

ID=6367476

Family Applications (1)

Application Number Title Priority Date Filing Date
DK579089A DK579089A (da) 1988-11-19 1989-11-17 Renin-inhiberende urinstofderivater af dipeptider, deres fremstilling og anvendelse

Country Status (12)

Country Link
EP (1) EP0370382A3 (hu)
JP (1) JPH02180898A (hu)
KR (1) KR900007868A (hu)
AU (1) AU616071B2 (hu)
DE (1) DE3839126A1 (hu)
DK (1) DK579089A (hu)
FI (1) FI895462A0 (hu)
HU (1) HU203771B (hu)
IL (1) IL92348A0 (hu)
NO (1) NO894569L (hu)
PT (1) PT92330A (hu)
ZA (1) ZA898784B (hu)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3841520A1 (de) * 1988-12-09 1990-06-13 Hoechst Ag Enzymhemmende harnstoffderivate von dipeptiden, verfahren zu ihrer herstellung, diese enthaltende mittel und ihre verwendung
DE4014421A1 (de) * 1990-05-05 1991-11-07 Merck Patent Gmbh Aminosaeurederivate
US10118918B2 (en) 2012-12-21 2018-11-06 Epizyme, Inc. PRMT5 inhibitors and uses thereof
CA2899363A1 (en) 2012-12-21 2014-06-26 Epizyme, Inc. Prmt5 inhibitors and uses thereof
WO2014100695A1 (en) 2012-12-21 2014-06-26 Epizyme, Inc. Prmt5 inhibitors and uses thereof
CA2894130A1 (en) 2012-12-21 2014-06-26 Epizyme, Inc. Prmt5 inhibitors containing a dihydro- or tetrahydroisoquinoline and uses thereof
PT2935222T (pt) 2012-12-21 2018-12-10 Epizyme Inc Inibidores de prmt5 e seus usos
AU2015301196A1 (en) 2014-08-04 2017-01-12 Epizyme, Inc. PRMT5 inhibitors and uses thereof

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA87563B (en) * 1986-02-03 1987-09-30 Squibb & Sons Inc N-heterocyclic alcohol renin inhibitors
DE3627877A1 (de) * 1986-07-30 1988-02-04 Hoechst Ag Renin-hemmende di- und tripeptide, verfahren zu deren herstellung, diese enthaltende mittel und ihre verwendung
GB8707412D0 (en) * 1987-03-27 1987-04-29 Fujisawa Pharmaceutical Co Peptide compounds
DE3841520A1 (de) * 1988-12-09 1990-06-13 Hoechst Ag Enzymhemmende harnstoffderivate von dipeptiden, verfahren zu ihrer herstellung, diese enthaltende mittel und ihre verwendung

Also Published As

Publication number Publication date
JPH02180898A (ja) 1990-07-13
HUT53122A (en) 1990-09-28
IL92348A0 (en) 1990-07-26
KR900007868A (ko) 1990-06-02
NO894569D0 (no) 1989-11-16
HU895948D0 (en) 1990-02-28
FI895462A0 (fi) 1989-11-16
EP0370382A3 (de) 1991-04-10
EP0370382A2 (de) 1990-05-30
DE3839126A1 (de) 1990-05-23
AU4479889A (en) 1990-08-09
DK579089D0 (da) 1989-11-17
AU616071B2 (en) 1991-10-17
PT92330A (pt) 1990-05-31
HU203771B (en) 1991-09-30
ZA898784B (en) 1990-08-29
NO894569L (no) 1990-05-21

Similar Documents

Publication Publication Date Title
DK620489A (da) Enzymhaemmende urinstofderivater af dipeptider, deres fremstilling og anvendelse som laegemidler
DK609489D0 (da) Imidazolderivater, deres fremstilling og anvendelse
DK374389D0 (da) Arylbenzenoxazolidinoner, deres fremstilling og anvendelse
DK306885D0 (da) Substituerede benzoatestere af 3-hydroxymorphinaner, deres fremstilling og anvendelse
DK374289D0 (da) Indazol-3-carboxylsyrederivater, deres fremstilling og anvendelse
DK605489A (da) Beta-amino-boronsyre-derivater, deres fremstilling og anvendelse
DK128889D0 (da) Arylpiperazinylalkoxyderivater af cycliske imider, deres fremstilling og anvendelse
NO895030D0 (no) 2-imino-benzotiazolinderivater og deres fremstilling.
DK388989A (da) Acylcyanoguanidiner, deres fremstilling og anvendelse
DK435289A (da) Piperazindioner, deres fremstilling og anvendelse
DK473289D0 (da) 2'-halogenmethyliden-, 2'-ethenyliden- og 2'-ethynyl-adenosin-derivater, deres fremstilling og anvendelse
DK579089D0 (da) Renin-inhiberende urinstofderivater af dipeptider, deres fremstilling og anvendelse
DK289585A (da) Arylderivater af heterobicycliske forbindelser, deres farmaceutiske anvendelse og deres fremstilling
DK360189D0 (da) S-adenosyl-methionin-decarboxylase-inhibitorer, deres fremstilling og anvendelse
DK225089D0 (da) 2-adamantyl-4-isothiazolin-3-oner, deres fremstilling og anvendelse
DK469389D0 (da) Piperidinyl-imidazol-derivater, deres fremstilling og anvendelse
DK0842148T3 (da) Derivater af benzensulfonamid, deres fremstilling og deres terapeutiske anvendelse
DK300488A (da) Mono- og polyhydroxyacylderivater af polyoxygenerede labdaner, deres fremstilling og anvendelse
DK0869952T3 (da) Derivater af 5-naphthalen-1-yl-1,3-dioxaner, fremstilling og terapeutisk anvendelse heraf
DK120989D0 (da) 1-carbonylderivater af 4-aryl-4-aryloxypiperidiner, deres fremstilling og anvendelse
DK185489D0 (da) Imidazolylmethyl-cycloalkanoebaaindoloner, deres fremstilling og anvendelse
DK592389D0 (da) Penemderivater, deres fremstilling og anvendelse
DK338589D0 (da) Morpholinoderivater af rhodomyciner, deres fremstilling og anvendelse
DK578689D0 (da) Renin-haemmende dipeptider, deres fremstilling og anvendelse
DK163589A (da) Sakyomycin e og derivater deraf, deres fremstilling og anvendelse

Legal Events

Date Code Title Description
ATS Application withdrawn