DK578882A - Farmaceutisk aktive phenylcarboxylsyrederivater - Google Patents

Farmaceutisk aktive phenylcarboxylsyrederivater Download PDF

Info

Publication number
DK578882A
DK578882A DK578882A DK578882A DK578882A DK 578882 A DK578882 A DK 578882A DK 578882 A DK578882 A DK 578882A DK 578882 A DK578882 A DK 578882A DK 578882 A DK578882 A DK 578882A
Authority
DK
Denmark
Prior art keywords
carboxylic acid
acid derivatives
pharmaceutical active
phenyl carboxylic
active phenyl
Prior art date
Application number
DK578882A
Other languages
Danish (da)
English (en)
Inventor
Peter R Bernstein
Alvin K Willard
Original Assignee
Ici America Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ici America Inc filed Critical Ici America Inc
Publication of DK578882A publication Critical patent/DK578882A/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C205/00Compounds containing nitro groups bound to a carbon skeleton
    • C07C205/49Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups
    • C07C205/57Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups having nitro groups and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
    • C07C205/59Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups having nitro groups and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton the carbon skeleton being further substituted by singly-bound oxygen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/41Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by hydrogenolysis or reduction of carboxylic groups or functional derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40Unsaturated compounds
    • C07C59/58Unsaturated compounds containing ether groups, groups, groups, or groups
    • C07C59/64Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40Unsaturated compounds
    • C07C59/76Unsaturated compounds containing keto groups
    • C07C59/90Unsaturated compounds containing keto groups containing singly bound oxygen-containing groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C65/00Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C65/32Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing keto groups
    • C07C65/40Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing keto groups containing singly bound oxygen-containing groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pulmonology (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DK578882A 1981-12-30 1982-12-30 Farmaceutisk aktive phenylcarboxylsyrederivater DK578882A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB8139027 1981-12-30

Publications (1)

Publication Number Publication Date
DK578882A true DK578882A (da) 1983-07-01

Family

ID=10526871

Family Applications (1)

Application Number Title Priority Date Filing Date
DK578882A DK578882A (da) 1981-12-30 1982-12-30 Farmaceutisk aktive phenylcarboxylsyrederivater

Country Status (11)

Country Link
US (1) US4499299A (fr)
EP (1) EP0083228B1 (fr)
JP (1) JPS58131936A (fr)
AT (1) ATE13286T1 (fr)
AU (1) AU9137082A (fr)
CA (1) CA1223601A (fr)
DE (1) DE3263573D1 (fr)
DK (1) DK578882A (fr)
IE (1) IE54269B1 (fr)
NZ (1) NZ202921A (fr)
ZA (1) ZA829046B (fr)

Families Citing this family (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5135940A (en) * 1982-09-23 1992-08-04 Merck Frosst Canada, Inc. Leukotriene antagonists
GR78697B (fr) * 1982-10-21 1984-09-27 Lilly Industries Ltd
US4539419A (en) * 1983-05-02 1985-09-03 Hoffmann-La Roche Inc. Naphthalenyloxy substituted carboxylic acids
US5105017A (en) * 1983-07-18 1992-04-14 Eli Lilly And Company Leukotriene antagonist intermediates
US4764521A (en) * 1983-07-18 1988-08-16 Eli Lilly And Company Leukotriene antagonists and a method of use there as
ES537023A0 (es) * 1983-10-27 1985-12-01 Merck Frosst Canada Inc Un procedimiento para la preparacion de nuevos antagonistas de los leucotrienos.
GB8333665D0 (en) * 1983-12-16 1984-01-25 Lilly Industries Ltd Organic compounds
GB8524157D0 (en) * 1984-10-19 1985-11-06 Ici America Inc Heterocyclic amides
GB8607294D0 (en) * 1985-04-17 1986-04-30 Ici America Inc Heterocyclic amide derivatives
US5179112A (en) * 1985-04-17 1993-01-12 Ici Americas Inc. Heterocyclic amide derivatives and pharmaceutical use
DE3515278A1 (de) * 1985-04-27 1986-10-30 Grünenthal GmbH, 5190 Stolberg Neue benzoesaeurederivate, diese enthaltende arzneimittel und verfahren zur herstellung dieser verbindungen und arzneimittel
DE3518655A1 (de) * 1985-05-24 1986-11-27 Grünenthal GmbH, 5190 Stolberg Neue phenolderivate, diese enthaltende arzneimittel und verfahren zur herstellung dieser verbindungen und arzneimittel
GB8623429D0 (en) * 1985-10-17 1986-11-05 Ici America Inc Carboximide derivatives
US4837235A (en) * 1985-10-17 1989-06-06 Ici Americas Inc. Indole and indazole keto sulphones as leukotriene antagonists
GB8609175D0 (en) * 1986-04-15 1986-05-21 Ici America Inc Heterocyclic carboxamides
US5294613A (en) * 1987-01-12 1994-03-15 Eli Lilly And Company Method of treating endotoxic shock in mammals
US4874777A (en) * 1987-04-10 1989-10-17 Eli Lilly And Company Leukotriene antagonists
US4853398A (en) * 1987-04-13 1989-08-01 Eli Lilly And Company Leukotriene antagonists and use thereas
US5003055A (en) * 1987-09-25 1991-03-26 Zaidan Hojin Biseibutsu Kagaku Kenkyu Kai Anthracycline derivatives having inhibitory activity against reverse transcriptase of human immunodeficiency virus
US5605930A (en) * 1991-10-21 1997-02-25 The United States Of America As Represented By The Department Of Health And Human Services Compositions and methods for treating and preventing pathologies including cancer
PH30449A (en) * 1991-11-25 1997-05-28 Lilly Co Eli Substituted phenyl phenol leukotriene antagonists
US6461643B2 (en) 1993-04-22 2002-10-08 Emisphere Technologies, Inc. Oral drug delivery compositions and methods
US5457124A (en) * 1993-12-07 1995-10-10 Hoffmann-La Roche Inc. Carboxylic acid Leukotriene B4 antagonists
US5688997A (en) * 1994-05-06 1997-11-18 Pharmacopeia, Inc. Process for preparing intermediates for a combinatorial dihydrobenzopyran library
US6790965B1 (en) 1994-05-06 2004-09-14 Pharmacopeia Drug Discovery, Inc. Combinatorial dihydrobenzopyran library
US6017768A (en) * 1994-05-06 2000-01-25 Pharmacopeia, Inc. Combinatorial dihydrobenzopyran library
AU691296B2 (en) * 1994-05-06 1998-05-14 Pharmacopeia Drug Discovery, Inc. Combinatorial dihydrobenzopyran library
US6001347A (en) 1995-03-31 1999-12-14 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
DE19603329A1 (de) 1996-01-31 1997-08-07 Bayer Ag Verfahren zur Herstellung von aromatischen Methoxycarbonsäuremethylestern
SI9720025A (sl) 1996-03-29 1999-08-31 Emishphere Technologies, Inc. Spojine in sestavki za prenos aktivne snovi
US6358504B1 (en) 1997-02-07 2002-03-19 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
EP1175390B1 (fr) 1999-04-05 2005-02-02 Emisphere Technologies, Inc. Sels disodiques, monohydrates et solvates ethanol pour liberer des agents actifs
US7279597B1 (en) 1999-11-05 2007-10-09 Emisphere Technologies, Inc. Phenyl amine carboxylic acid compounds and compositions for delivering active agents
CA2388240C (fr) * 1999-11-05 2010-04-20 Emisphere Technologies, Inc. Composes d'acide carboxylique phenoxy et compositions utilisees afin de diffuser des agents actifs
US7129274B1 (en) 1999-11-05 2006-10-31 Emisphere Technologies Inc. Phenoxy carboxylic acid compounds and compositions for delivering active agents
JP4850379B2 (ja) * 1999-12-16 2012-01-11 エミスフェアー・テクノロジーズ・インク 活性剤を輸送するための化合物及び組成物
US7238835B2 (en) * 2003-12-22 2007-07-03 Sanofi-Aventis Deutschland Gmbh Process for the preparation of substituted 2-(phenoxymethyl) benzoic acids
DE102008008838A1 (de) 2008-02-13 2009-08-20 Bayer Healthcare Ag Cycloalkoxy-substituierte 4-Phenyl-3,5-dicyanopyridine und ihre Verwendung
US8093253B2 (en) * 2008-03-06 2012-01-10 Hoffmann-La Roche Inc. Leukotriene B4 inhibitors
WO2019120235A1 (fr) * 2017-12-22 2019-06-27 中国科学院上海药物研究所 Classe de dérivés d'acide phénylcarboxylique, procédé de préparation associé et utilisation correspondante

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE7897T1 (de) * 1979-09-05 1984-06-15 Glaxo Group Limited Phenol-derivate, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische zusammensetzungen.
GB2058785B (en) * 1979-09-05 1983-05-25 Glaxo Group Ltd Phenol derivatives

Also Published As

Publication number Publication date
IE54269B1 (en) 1989-08-02
CA1223601A (fr) 1987-06-30
ZA829046B (en) 1983-09-28
EP0083228A1 (fr) 1983-07-06
US4499299A (en) 1985-02-12
EP0083228B1 (fr) 1985-05-15
AU9137082A (en) 1983-07-07
IE822885L (en) 1983-06-30
DE3263573D1 (en) 1985-06-20
NZ202921A (en) 1986-03-14
JPS58131936A (ja) 1983-08-06
ATE13286T1 (de) 1985-06-15

Similar Documents

Publication Publication Date Title
DK578882A (da) Farmaceutisk aktive phenylcarboxylsyrederivater
IT1207269B (it) Difenilbutilpiperazincarbossammidi, loro sali di addizione con acidi e composizioni farmaceutiche; procedimenti di fabbricazione ed uso.
PT99597B (pt) Processo para a preparacao de derivados do acido hidroxamico que inibem a lipoxigenase
SE8402549L (sv) Substituerade moranolinderivat
ATE2427T1 (de) (dl)-16-phenoxy- und 16-substituierte phenoxy-9- keto prostatriensaeuren und derivate, verfahren zu deren herstellung und ihre pharmazeutischen zusammensetzungen.
IT8620846A0 (it) Derivati di acido valproico e di acido (e)-2-valproenoico, procedimento per la loro preparazione e relative composizioni farmaceutiche.
PT82987B (pt) Processo para a preparacao de novos de derivados de acidos carboxilicos bem como de composicoes farmaceuticas que os contem
MA19882A1 (fr) Derives d'acides w-amines, leur preparation et utilisation ainsi que les compositions contenant ces acides.
IT8025159A0 (it) Preparato medicinale ad azione citostatica, nonche' derivati dell'acido isocianurico eprocedimento per la loro preparazione.
DK199789A (da) Anvendelse af et phenylquinolincarboxylsyrederivat eller et farmaceutisk egnet salt deraf til fremstilling af et topisk farmaceutisk praeparat til behandling af hud- og/eller slimepithelsygdomme
IT8019992A0 (it) Derivati dell'acido 3-fosfonocefalosporanico, procedimenti per la loro preparazione e composizione farmaceutica che li comprende.
OA07539A (fr) Nouveaux dérivés d'acides phényl aliphatiques, leur préparation, leur application comme médicaments, et les compositions les renfermant.
IT8322648A0 (it) Derivati dell'acido 4-fenil4-osso-buten 2-oico, loro procedimento di preparazione e loro applicazione come prodotti medicinali.
IT1174760B (it) Derivati di acido 4-idrossi 3-chinolin carbossilico sostituiti in 2,loro preparazione,loro applicazione come medicamenti,composizioni che li contengono ed imtermedi ottenuti
ATE236133T1 (de) Benzimidazolderivate
FR2449686B1 (fr) Nouvel ester de l'acide 1-(p-chlorobenzoyl)-5-methoxy-2-methylindole-3-acetique et sa preparation, ainsi que medicament le comprenant et sa preparation
IT8024165A0 (it) Esteri di acidi dialogenovinilciclopropancarbossili ci, procedimento per la loro preparazione e loro impiego per combattere organismi nocivi e anche alcooli alfa-alogenoetinil-3-fenossi-benzilici.
FR2580648B1 (fr) Nouveaux derives du triazole, leur procede de preparation et les compositions pharmaceutiques les renfermant
SE8205523D0 (sv) Antranilsyraestrar, forfarande for framstellning derav och farmaceutiska kompositioner som innehaller dem
IT8026179A0 (it) Procedimento per la preparazione di derivati di esteri dell'acido apovincaminico.
IT1157268B (it) Derivati dagli acidi alfa o beta mercaptopropionilammidoacetici, processo per la loro preparazione e composizioni terapeutiche che li comprendono come principio attivo
IT8220190A0 (it) Procedimento per la loro derivati dell'acido preparazione e composizioni d-2-(6-metossi-2-naftil) propionico farmaceutiche che li contengono. ad attivita' terapeutica,
SE7614304L (sv) Nya karboxylsyraderivat och sett for deras framstellning
SE7907251L (sv) Nya metyl-l-piperidinol-4-estrar och sett att framstella dessa samt farmaceutiska kompositioner, innehallande nemnda estrar
ES508757A0 (es) "procedimiento para la preparacion de acidos antranilicos sustituidos con radicales basicos"

Legal Events

Date Code Title Description
AHS Application shelved for other reasons than non-payment