DK568882A - Fremgangsmaade til fremstilling af dihydro- eller tetrahydromonacolin-l, metalsalte eller alkylestere deraf - Google Patents

Fremgangsmaade til fremstilling af dihydro- eller tetrahydromonacolin-l, metalsalte eller alkylestere deraf Download PDF

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Publication number
DK568882A
DK568882A DK568882A DK568882A DK568882A DK 568882 A DK568882 A DK 568882A DK 568882 A DK568882 A DK 568882A DK 568882 A DK568882 A DK 568882A DK 568882 A DK568882 A DK 568882A
Authority
DK
Denmark
Prior art keywords
hydromonacolin
tetra
metal salts
alkyl esters
preparing dihydro
Prior art date
Application number
DK568882A
Other languages
English (en)
Inventor
Akira Endo
Original Assignee
Akira Endo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP56214788A external-priority patent/JPS58109480A/ja
Priority claimed from JP2374582A external-priority patent/JPS58144318A/ja
Application filed by Akira Endo filed Critical Akira Endo
Publication of DK568882A publication Critical patent/DK568882A/da

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/01Saturated compounds having only one carboxyl group and containing hydroxy or O-metal groups
    • C07C59/11Saturated compounds having only one carboxyl group and containing hydroxy or O-metal groups containing rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40Unsaturated compounds
    • C07C59/42Unsaturated compounds containing hydroxy or O-metal groups
    • C07C59/46Unsaturated compounds containing hydroxy or O-metal groups containing rings other than six-membered aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D309/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/16Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D309/28Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/30Oxygen atoms, e.g. delta-lactones
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/14Fungi; Culture media therefor
    • C12N1/145Fungal isolates
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/02Oxygen as only ring hetero atoms
    • C12P17/06Oxygen as only ring hetero atoms containing a six-membered hetero ring, e.g. fluorescein
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12RINDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00Microorganisms ; Processes using microorganisms
    • C12R2001/645Fungi ; Processes using fungi

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Medicinal Chemistry (AREA)
  • Mycology (AREA)
  • Virology (AREA)
  • Botany (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DK568882A 1981-12-23 1982-12-22 Fremgangsmaade til fremstilling af dihydro- eller tetrahydromonacolin-l, metalsalte eller alkylestere deraf DK568882A (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP56214788A JPS58109480A (ja) 1981-12-23 1981-12-23 新生理活性物質ジヒドロモナコリンl及びその製造法
JP2374582A JPS58144318A (ja) 1982-02-17 1982-02-17 テトラヒドロモナコリンlおよびその誘導体並びにそれを有効成分とする高脂血症治療剤

Publications (1)

Publication Number Publication Date
DK568882A true DK568882A (da) 1983-06-24

Family

ID=26361156

Family Applications (1)

Application Number Title Priority Date Filing Date
DK568882A DK568882A (da) 1981-12-23 1982-12-22 Fremgangsmaade til fremstilling af dihydro- eller tetrahydromonacolin-l, metalsalte eller alkylestere deraf

Country Status (9)

Country Link
AU (1) AU9133682A (da)
BE (1) BE895445A (da)
DE (1) DE3247175A1 (da)
DK (1) DK568882A (da)
FR (1) FR2518546A1 (da)
GB (1) GB2111989B (da)
IT (1) IT8249711A0 (da)
NL (1) NL8204904A (da)
SE (1) SE8207306L (da)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5354772A (en) * 1982-11-22 1994-10-11 Sandoz Pharm. Corp. Indole analogs of mevalonolactone and derivatives thereof
US4472426A (en) * 1982-12-22 1984-09-18 Merck & Co., Inc. Antihypercholesterolemic compounds
US4613610A (en) * 1984-06-22 1986-09-23 Sandoz Pharmaceuticals Corp. Cholesterol biosynthesis inhibiting pyrazole analogs of mevalonolactone and its derivatives
US4804679A (en) * 1984-07-24 1989-02-14 Sandoz Pharm. Corp. Erythro-(E)-7-(3'-C1-3alkyl-1'-(3",5"-dimethylphenyl)naphth-2'-yl)-3,5-dihydroxyhept-6-enoic acids and derivatives thereof
US4686237A (en) * 1984-07-24 1987-08-11 Sandoz Pharmaceuticals Corp. Erythro-(E)-7-[3'-C1-3 alkyl-1'-(3",5"-dimethylphenyl)naphth-2'-yl]-3,5-dihydroxyhept-6-enoic acids and derivatives thereof
US4647576A (en) * 1984-09-24 1987-03-03 Warner-Lambert Company Trans-6-[2-(substitutedpyrrol-1-yl)alkyl]-pyran-2-one inhibitors of cholesterol synthesis
US4668794A (en) * 1985-05-22 1987-05-26 Sandoz Pharm. Corp. Intermediate imidazole acrolein analogs

Also Published As

Publication number Publication date
FR2518546A1 (fr) 1983-06-24
SE8207306L (sv) 1983-06-24
IT8249711A0 (it) 1982-12-21
DE3247175A1 (de) 1983-07-07
SE8207306D0 (sv) 1982-12-21
NL8204904A (nl) 1983-07-18
GB2111989B (en) 1985-05-09
BE895445A (fr) 1983-04-15
GB2111989A (en) 1983-07-13
AU9133682A (en) 1983-06-30

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