DK555687A - Fremgangsmaade til fremstilling af n,n-diaryl-urinstoffer - Google Patents

Fremgangsmaade til fremstilling af n,n-diaryl-urinstoffer

Info

Publication number
DK555687A
DK555687A DK555687A DK555687A DK555687A DK 555687 A DK555687 A DK 555687A DK 555687 A DK555687 A DK 555687A DK 555687 A DK555687 A DK 555687A DK 555687 A DK555687 A DK 555687A
Authority
DK
Denmark
Prior art keywords
diaryl
procedure
manufacturing
Prior art date
Application number
DK555687A
Other languages
Danish (da)
English (en)
Other versions
DK555687D0 (da
Inventor
Wolfram Kissener
Joachim Franke
Helmut Fiege
Karlfried Wedemeyer
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of DK555687D0 publication Critical patent/DK555687D0/da
Publication of DK555687A publication Critical patent/DK555687A/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C273/00—Preparation of urea or its derivatives, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C273/18—Preparation of urea or its derivatives, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups of substituted ureas
    • C07C273/1809—Preparation of urea or its derivatives, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups of substituted ureas with formation of the N-C(O)-N moiety
    • C07C273/1818—Preparation of urea or its derivatives, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups of substituted ureas with formation of the N-C(O)-N moiety from -N=C=O and XNR'R"
    • C07C273/1827—X being H

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
DK555687A 1986-10-24 1987-10-23 Fremgangsmaade til fremstilling af n,n-diaryl-urinstoffer DK555687A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19863636190 DE3636190A1 (de) 1986-10-24 1986-10-24 Verfahren zur herstellung von n,n-diaryl-harnstoffen

Publications (2)

Publication Number Publication Date
DK555687D0 DK555687D0 (da) 1987-10-23
DK555687A true DK555687A (da) 1988-04-25

Family

ID=6312378

Family Applications (1)

Application Number Title Priority Date Filing Date
DK555687A DK555687A (da) 1986-10-24 1987-10-23 Fremgangsmaade til fremstilling af n,n-diaryl-urinstoffer

Country Status (7)

Country Link
US (1) US4820871A (cs)
EP (1) EP0264752B1 (cs)
JP (1) JPS63122660A (cs)
CA (1) CA1295340C (cs)
DE (2) DE3636190A1 (cs)
DK (1) DK555687A (cs)
ES (1) ES2016957B3 (cs)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2066049T3 (es) * 1989-07-28 1995-03-01 Chemie Linz Gmbh Procedimiento para la obtencion de ureas asimetricamente substituidas.
US5248755A (en) * 1989-07-28 1993-09-28 Chemie Linz Gesellschaft M.B.H. Process for the preparation of asymmetrically substituted ureas, carbamates or thiocarbamates
US5220061A (en) * 1992-02-07 1993-06-15 Arco Chemical Technology, L.P. Selective process for the preparation of diphenylmethane bis-(dialkyl ureas
JP3372436B2 (ja) * 1996-11-28 2003-02-04 オークマ株式会社 インバータの制御装置
US6344476B1 (en) 1997-05-23 2002-02-05 Bayer Corporation Inhibition of p38 kinase activity by aryl ureas
US20080300281A1 (en) * 1997-12-22 2008-12-04 Jacques Dumas Inhibition of p38 Kinase Activity Using Aryl and Heteroaryl Substituted Heterocyclic Ureas
US7329670B1 (en) * 1997-12-22 2008-02-12 Bayer Pharmaceuticals Corporation Inhibition of RAF kinase using aryl and heteroaryl substituted heterocyclic ureas
US7517880B2 (en) * 1997-12-22 2009-04-14 Bayer Pharmaceuticals Corporation Inhibition of p38 kinase using symmetrical and unsymmetrical diphenyl ureas
US20080269265A1 (en) * 1998-12-22 2008-10-30 Scott Miller Inhibition Of Raf Kinase Using Symmetrical And Unsymmetrical Substituted Diphenyl Ureas
WO2000042012A1 (en) 1999-01-13 2000-07-20 Bayer Corporation φ-CARBOXYARYL SUBSTITUTED DIPHENYL UREAS AS RAF KINASE INHIBITORS
US8124630B2 (en) 1999-01-13 2012-02-28 Bayer Healthcare Llc ω-carboxyaryl substituted diphenyl ureas as raf kinase inhibitors
US7928239B2 (en) 1999-01-13 2011-04-19 Bayer Healthcare Llc Inhibition of RAF kinase using quinolyl, isoquinolyl or pyridyl ureas
RU2319693C9 (ru) * 1999-01-13 2008-08-20 Байер Копэрейшн Производные мочевины (варианты), фармацевтическая композиция (варианты) и способ лечения заболевания, связанного с ростом раковых клеток (варианты)
EP1158985B1 (en) * 1999-01-13 2011-12-28 Bayer HealthCare LLC OMEGA-CARBOXY ARYL SUBSTITUTED DIPHENYL UREAS AS p38 KINASE INHIBITORS
MXPA02002578A (es) 1999-09-08 2002-10-23 Guilford Pharm Inc Compuestos de union a ciclofilina no peptidicos, y su uso.
US7235576B1 (en) 2001-01-12 2007-06-26 Bayer Pharmaceuticals Corporation Omega-carboxyaryl substituted diphenyl ureas as raf kinase inhibitors
CA2435829A1 (en) 2001-01-25 2002-08-01 Guilford Pharmaceuticals Inc. Trisubstituted carbocyclic cyclophilin binding compounds and their use
US7371763B2 (en) * 2001-04-20 2008-05-13 Bayer Pharmaceuticals Corporation Inhibition of raf kinase using quinolyl, isoquinolyl or pyridyl ureas
ATE345130T1 (de) * 2001-12-03 2006-12-15 Bayer Pharmaceuticals Corp Arylharnstoff-verbindungen in kombination mit anderen zytostatisch oder zytotoxisch wirksamen stoffen zur behandlungen menschlicher krebserkrankungen
US20080108672A1 (en) * 2002-01-11 2008-05-08 Bernd Riedl Omega-Carboxyaryl Substituted Diphenyl Ureas As Raf Kinase Inhibitors
CA2475703C (en) * 2002-02-11 2016-12-20 Bayer Pharmaceuticals Corporation Aryl ureas with angiogenesis inhibiting activity
US20030216396A1 (en) 2002-02-11 2003-11-20 Bayer Corporation Pyridine, quinoline, and isoquinoline N-oxides as kinase inhibitors
DK1580188T3 (da) 2002-02-11 2012-02-06 Bayer Healthcare Llc Forbindelser af arylurea som kinaseinhibitorer
AU2003210969A1 (en) * 2002-02-11 2003-09-04 Bayer Corporation Aryl ureas with raf kinase and angiogenesis inhibiting activity
UY28213A1 (es) * 2003-02-28 2004-09-30 Bayer Pharmaceuticals Corp Nuevos derivados de cianopiridina útiles en el tratamiento de cáncer y otros trastornos.
WO2004113274A2 (en) * 2003-05-20 2004-12-29 Bayer Pharmaceuticals Corporation Diaryl ureas with kinase inhibiting activity
EA010485B1 (ru) * 2003-07-23 2008-10-30 Байер Фамэсьютиклс Копэрейшн Производное n,n'-дифенилмочевины, фармацевтическая композиция (варианты) и способ лечения и предупреждения заболеваний и состояний с его использованием (варианты)
WO2005110994A2 (en) * 2004-04-30 2005-11-24 Bayer Pharmaceuticals Corporation Substituted pyrazolyl urea derivatives useful in the treatment of cancer
CN102924336A (zh) * 2012-09-28 2013-02-13 黎明化工研究设计院有限责任公司 一种制备n-甲基-n’，n’-二苯基脲的方法
CN103232371B (zh) * 2013-04-26 2014-11-26 黎明化工研究设计院有限责任公司 一种制备n-甲基-n’，n’-二苯基脲的方法
JP2020526646A (ja) * 2017-07-11 2020-08-31 コベストロ、ドイチュラント、アクチエンゲゼルシャフトＣｏｖｅｓｔｒｏ Ｄｅｕｔｓｃｈｌａｎｄ Ａｇ ハロゲン非含有難燃剤を含む軟質フォーム
US12091377B2 (en) 2018-12-07 2024-09-17 Dow Global Technologies Llc. Method for converting monoisocyanates to ureas

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2683727A (en) * 1954-07-13 Secondary aromatic amines
CH513134A (de) * 1968-06-10 1971-09-30 Bayer Ag Verfahren zur Herstellung von N-Arylharnstoffen
JPS5419937A (en) * 1977-07-12 1979-02-15 Showa Denko Kk Preparation of urea substitution product
DE2928485A1 (de) * 1979-07-14 1981-01-29 Bayer Ag Verwendung von harnstoffderivaten als arzneimittel bei der behandlung von fettstoffwechselstoerungen
US4410697A (en) * 1980-01-25 1983-10-18 Reanal Finomvegyszergyar Process for the preparation of N-aryl-N'-(mono- or di substituted)-urea derivatives
IT1137177B (it) * 1981-06-02 1986-09-03 Anic Spa Processo per la preparazione di uree asimmetriche a partire da uretani ed ammine
US4473579A (en) * 1982-01-26 1984-09-25 American Cyanamid Company Antiatherosclerotic tetrasubstituted ureas and thioureas

Also Published As

Publication number Publication date
DK555687D0 (da) 1987-10-23
CA1295340C (en) 1992-02-04
DE3764602D1 (de) 1990-10-04
DE3636190A1 (de) 1988-04-28
EP0264752A1 (de) 1988-04-27
JPH0360817B2 (cs) 1991-09-17
EP0264752B1 (de) 1990-08-29
US4820871A (en) 1989-04-11
JPS63122660A (ja) 1988-05-26
ES2016957B3 (es) 1990-12-16

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