DK54787D0 - Fremgangsmaade til fremstilling af l-alfa-hydroxyvitamin d forbindelser og mellemprodukter til brug herved - Google Patents

Fremgangsmaade til fremstilling af l-alfa-hydroxyvitamin d forbindelser og mellemprodukter til brug herved

Info

Publication number
DK54787D0
DK54787D0 DK054787A DK54787A DK54787D0 DK 54787 D0 DK54787 D0 DK 54787D0 DK 054787 A DK054787 A DK 054787A DK 54787 A DK54787 A DK 54787A DK 54787 D0 DK54787 D0 DK 54787D0
Authority
DK
Denmark
Prior art keywords
hydroxyvitamin
alfa
intermediates
compounds
procedure
Prior art date
Application number
DK054787A
Other languages
Danish (da)
English (en)
Other versions
DK54787A (da
Inventor
Hector F Deluca
Heinrich K Schnoes
Seok Ho Lee
Original Assignee
Wisconsin Alumni Res Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wisconsin Alumni Res Found filed Critical Wisconsin Alumni Res Found
Publication of DK54787A publication Critical patent/DK54787A/da
Publication of DK54787D0 publication Critical patent/DK54787D0/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/27Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation
    • C07C45/29Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation of hydroxy groups
    • C07C45/296Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation of hydroxy groups with lead derivatives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C35/00Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a ring other than a six-membered aromatic ring
    • C07C35/22Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a ring other than a six-membered aromatic ring polycyclic, at least one hydroxy group bound to a condensed ring system
    • C07C35/23Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a ring other than a six-membered aromatic ring polycyclic, at least one hydroxy group bound to a condensed ring system with hydroxy on a condensed ring system having two rings
    • C07C35/32Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a ring other than a six-membered aromatic ring polycyclic, at least one hydroxy group bound to a condensed ring system with hydroxy on a condensed ring system having two rings the condensed ring system being a (4.3.0) system, e.g. indenols
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C401/00Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/27Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation
    • C07C45/30Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation with halogen containing compounds, e.g. hypohalogenation
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C47/00Compounds having —CHO groups
    • C07C47/20Unsaturated compounds having —CHO groups bound to acyclic carbon atoms
    • C07C47/26Unsaturated compounds having —CHO groups bound to acyclic carbon atoms containing hydroxy groups
    • C07C47/267Unsaturated compounds having —CHO groups bound to acyclic carbon atoms containing hydroxy groups containing rings other than six-membered aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C47/00Compounds having —CHO groups
    • C07C47/20Unsaturated compounds having —CHO groups bound to acyclic carbon atoms
    • C07C47/277Unsaturated compounds having —CHO groups bound to acyclic carbon atoms containing ether groups, groups, groups, or groups
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK054787A 1985-06-10 1987-02-03 Fremgangsmaade til fremstilling af l-alfa-hydroxyvitamin d forbindelser og mellemprodukter til brug herved DK54787D0 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/743,129 US4755329A (en) 1985-06-10 1985-06-10 Process and intermediates for preparing 1α-hydroxyvitamin D compounds
PCT/US1986/001088 WO1986007364A1 (en) 1985-06-10 1986-05-20 PROCESS AND INTERMEDIATES FOR PREPARING 1alpha-HYDROXYVITAMIN D COMPOUNDS

Publications (2)

Publication Number Publication Date
DK54787A DK54787A (da) 1987-02-03
DK54787D0 true DK54787D0 (da) 1987-02-03

Family

ID=24987631

Family Applications (1)

Application Number Title Priority Date Filing Date
DK054787A DK54787D0 (da) 1985-06-10 1987-02-03 Fremgangsmaade til fremstilling af l-alfa-hydroxyvitamin d forbindelser og mellemprodukter til brug herved

Country Status (9)

Country Link
US (1) US4755329A (ja)
EP (1) EP0225915A4 (ja)
JP (3) JPS63500033A (ja)
AU (1) AU598469B2 (ja)
CA (1) CA1304389C (ja)
DK (1) DK54787D0 (ja)
GB (1) GB2178424B (ja)
IE (1) IE58441B1 (ja)
WO (1) WO1986007364A1 (ja)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2564841B2 (ja) * 1987-08-19 1996-12-18 日産化学工業株式会社 光学活性な液晶化合物
JPH0667896B2 (ja) * 1988-03-09 1994-08-31 大同ほくさん株式会社 1β,7,8―トリヒドロキシビタミンD2若しくはD3またはそれらの誘導体、およびそれらの製造方法
US5283345A (en) * 1988-03-09 1994-02-01 Hoxan Corporation 1β,7,8-trihydroxy vitamin D2, 1∘,7,8-trihydroxy vitamin D3 and their derivatives and method of manufacturing these chemicals
US20040009958A1 (en) * 1991-01-08 2004-01-15 Bone Care International, Inc. Methods for preparation and use of 1alpha,24(S)-dihydroxyvitamin D2
US5786348A (en) * 1991-01-08 1998-07-28 Bone Care International, Inc. Methods for preparation and use of 1α,24(S)-dihydroxy vitamin D2
AU650751B2 (en) * 1991-05-28 1994-06-30 Wisconsin Alumni Research Foundation Novel synthesis of 19-nor vitamin D compounds
DK0521550T3 (da) * 1991-07-05 1996-11-04 Duphar Int Res Vitamin D forbindelse, fremgangsmåde til fremstilling af denne forbindelse og mellemprodukt derfor
US5300705A (en) * 1993-03-18 1994-04-05 Hoffmann-La Roche Inc. Process for the preparation of 1α,25,26-trihydroxy-22-ene-cholecalciferol
WO2010088304A1 (en) 2009-01-27 2010-08-05 Cytotech Labs, Llc Vitamin d3 and analogs thereof for alleviating side effects associated with chemotherapy
MX338746B (es) 2009-08-14 2016-04-29 Berg Llc Vitamina d3 y analogos de la misma para tratar alopecia.
JP6608810B2 (ja) 2013-05-29 2019-11-20 バーグ エルエルシー ビタミンdを使用する化学療法誘発性脱毛症の予防又は軽減

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4225596A (en) * 1978-10-13 1980-09-30 Wisconsin Alumni Research Foundation Method for treating calcium imbalance and improving calcium absorption in mammals
US4594432A (en) * 1983-01-28 1986-06-10 Hoffman-La Roche Inc. Process for the synthesis of 1α,23(S),25-trihydroxycholecalciferol and 1α,23(R),25-trihydroxycholecalciferol
US4448726A (en) * 1983-05-11 1984-05-15 Wisconsin Alumni Research Foundation Ring A- and triene-modified vitamin D compounds
US4594340A (en) * 1984-11-29 1986-06-10 Hoffmann-La Roche Inc. 25,26-dehydro-1α,24R-dihydroxycholecalciferol and 25,26-dehydro-1α,24S-dihydroxycholecalciferol and the epimeric mixture

Also Published As

Publication number Publication date
JPH0662558B2 (ja) 1994-08-17
US4755329A (en) 1988-07-05
IE861526L (en) 1986-12-10
DK54787A (da) 1987-02-03
AU598469B2 (en) 1990-06-28
JPH0523251B2 (ja) 1993-04-02
GB2178424B (en) 1989-07-26
EP0225915A4 (en) 1987-08-12
GB8613945D0 (en) 1986-07-16
JPS63500033A (ja) 1988-01-07
EP0225915A1 (en) 1987-06-24
JPH08259479A (ja) 1996-10-08
WO1986007364A1 (en) 1986-12-18
CA1304389C (en) 1992-06-30
JPH05271182A (ja) 1993-10-19
JP2741497B2 (ja) 1998-04-15
IE58441B1 (en) 1993-09-22
AU5951186A (en) 1987-01-07
GB2178424A (en) 1987-02-11

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