DK543779A - Fremgangsmaade til fremstilling af nye lipopeptider diastereomerblandinger af saadanne forbindelser samt salte og komplekser deraf - Google Patents

Fremgangsmaade til fremstilling af nye lipopeptider diastereomerblandinger af saadanne forbindelser samt salte og komplekser deraf

Info

Publication number
DK543779A
DK543779A DK543779A DK543779A DK543779A DK 543779 A DK543779 A DK 543779A DK 543779 A DK543779 A DK 543779A DK 543779 A DK543779 A DK 543779A DK 543779 A DK543779 A DK 543779A
Authority
DK
Denmark
Prior art keywords
complexes
salts
compounds
procedure
preparation
Prior art date
Application number
DK543779A
Other languages
English (en)
Inventor
L Tarcsay
B Kamber
J Stanek
G Baschang
A Hartmann
Original Assignee
Ciba Geigy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy filed Critical Ciba Geigy
Publication of DK543779A publication Critical patent/DK543779A/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/24—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
    • C07K14/245—Escherichia (G)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0802—Tripeptides with the first amino acid being neutral
    • C07K5/0804—Tripeptides with the first amino acid being neutral and aliphatic
    • C07K5/081—Tripeptides with the first amino acid being neutral and aliphatic the side chain containing O or S as heteroatoms, e.g. Cys, Ser
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1002—Tetrapeptides with the first amino acid being neutral
    • C07K5/1005—Tetrapeptides with the first amino acid being neutral and aliphatic
    • C07K5/1013—Tetrapeptides with the first amino acid being neutral and aliphatic the side chain containing O or S as heteroatoms, e.g. Cys, Ser
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Steroid Compounds (AREA)
DK543779A 1978-12-20 1979-12-19 Fremgangsmaade til fremstilling af nye lipopeptider diastereomerblandinger af saadanne forbindelser samt salte og komplekser deraf DK543779A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH1294278 1978-12-20

Publications (1)

Publication Number Publication Date
DK543779A true DK543779A (da) 1980-06-21

Family

ID=4387836

Family Applications (1)

Application Number Title Priority Date Filing Date
DK543779A DK543779A (da) 1978-12-20 1979-12-19 Fremgangsmaade til fremstilling af nye lipopeptider diastereomerblandinger af saadanne forbindelser samt salte og komplekser deraf

Country Status (5)

Country Link
US (1) US4439425A (da)
EP (1) EP0014815A3 (da)
JP (1) JPS5585553A (da)
AU (1) AU5399979A (da)
DK (1) DK543779A (da)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0114787B1 (de) * 1983-01-25 1991-09-25 Ciba-Geigy Ag Neue Peptidderivate
FR2546164B1 (fr) * 1983-05-16 1987-07-17 Centre Nat Rech Scient Nouveaux derives de peptides, leur preparation et leur application comme inhibiteurs de l'elastase
US6074650A (en) * 1985-06-24 2000-06-13 Hoechst Aktiengesellschaft Membrane anchor/active compound conjugate, its preparation and its uses
US6024964A (en) * 1985-06-24 2000-02-15 Hoechst Aktiengesellschaft Membrane anchor/active compound conjugate, its preparation and its uses
DE3546150A1 (de) * 1985-06-24 1987-01-22 Hoechst Ag Membrananker-wirkstoffkonjugat, seine herstellung sowie seine verwendung
DE3522638A1 (de) * 1985-06-25 1987-01-08 Diamalt Ag Neue somatostatin-derivate
DE3700173A1 (de) * 1987-01-05 1988-07-14 Hoechst Ag Verfahren zur herstellung von lipophilen aminosaeurederivaten sowie lipophile aminosaeurederivate
AU626797B2 (en) * 1987-09-08 1992-08-13 Albany Medical College Immunogenic composites capable of selectively inducing antibody production, pharmaceutical compositions employing the same and method of selectively inducing antibody production
EP0383752B1 (en) * 1987-10-16 1994-05-11 EASTMAN KODAK COMPANY (a New Jersey corporation) Powder diffraction method and apparatus
DE4119856A1 (de) * 1991-06-17 1992-12-24 Hoechst Ag N-acyl-s-(2-hydroxyalkyl)-cysteine, deren herstellung sowie deren verwendung als zwischenprodukte zur herstellung von synthetischen immunadjuvantien und synthetischen impfstoffen
DE59207848D1 (de) * 1991-12-19 1997-02-20 Ciba Geigy Ag Aminosulfonsäurederivate und Verfahren zu ihrer Herstellung
AU666789B2 (en) * 1992-12-28 1996-02-22 Takeda Chemical Industries Ltd. 2-amino-6,7-dihydroxy-4-thiaheptanoic acid derivatives, production and use thereof
CA2128552A1 (en) * 1993-07-22 1995-01-23 Takeda Chemical Industries, Ltd. Derivatives of 6,7-dihydroxy-4-thiaheptanoic acid and their use
EP0641776A3 (en) * 1993-09-08 1997-05-02 Takeda Chemical Industries Ltd Thioglycerol derivatives.
US5700904A (en) * 1995-06-07 1997-12-23 Eli Lilly And Company Preparation of an acylated protein powder
US6251405B1 (en) 1995-06-07 2001-06-26 Connaught Laboratories, Inc. Immunological combination compositions and methods
FR2735478B1 (fr) * 1995-06-13 1997-08-22 Pasteur Institut Molecules polypeptidiques de stade pre-erythrocytaire du paludisme
WO1998023281A1 (en) * 1996-11-26 1998-06-04 Pharmagenesis, Inc. ANTIFUNGAL COMPOUNDS FROM $i(PSEUDOMONAS VIRIDIFLAVA)
DE19652586A1 (de) * 1996-12-17 1998-06-18 Biotechnolog Forschung Gmbh Dhc-Peptid und Mittel
US20060029653A1 (en) * 1997-01-29 2006-02-09 Cronk Peter J Therapeutic delivery system
US6696412B1 (en) 2000-01-20 2004-02-24 Cubist Pharmaceuticals, Inc. High purity lipopeptides, Lipopeptide micelles and processes for preparing same
US20060014674A1 (en) * 2000-12-18 2006-01-19 Dennis Keith Methods for preparing purified lipopeptides
AU2002246687C1 (en) * 2000-12-18 2009-11-05 Cubist Pharmaceuticals Llc Methods for preparing purified lipopeptides
WO2002059145A1 (en) * 2000-12-18 2002-08-01 Cubist Pharmaceuticals, Inc. Methods for preparing purified lipopeptides
US20050158329A1 (en) * 2004-01-21 2005-07-21 Ghosh Swapan K. Novel phytol derived immunoadjuvants and their use in vaccine formulations
JP2010502310A (ja) 2006-08-30 2010-01-28 ディヴィッド・ウィリアム・スミス 押出成形された材料に単軸又は多軸方向の剛性を付与する方法及び同方法により得られる製品
MX2011010050A (es) 2009-03-25 2011-12-14 Univ Texas Composiciones para estimulación de resistencia inmune innata de mamiferos a patógenos.
US20120238491A1 (en) * 2009-04-10 2012-09-20 Therimunex Pharmaceuticals, Inc. Immunologically active lipopeptides and methods for use thereof
US20110000483A1 (en) * 2009-05-01 2011-01-06 Matthias Joseph A External nasal dilator
AR079127A1 (es) 2009-11-23 2011-12-28 Cubist Pharm Inc Composiciones de daptomicina y metodos relacionados
CN102241732B (zh) * 2011-05-30 2015-01-21 浙江海正药业股份有限公司 一种脂肽化合物的纯化方法
CN105555756B (zh) 2013-06-28 2018-12-07 奥克兰联合服务有限公司 氨基酸缀合物和肽缀合物及缀合方法
WO2016044839A2 (en) 2014-09-19 2016-03-24 The Board Of Regents Of The University Of Texas System Compositions and methods for treating viral infections through stimulated innate immunity in combination with antiviral compounds
CN107250103A (zh) 2014-12-23 2017-10-13 玛格丽特·安妮·布林布尔 氨基酸缀合物和肽缀合物以及其用途
KR20180128915A (ko) 2016-02-26 2018-12-04 오클랜드 유니서비시즈 리미티드 아미노산 및 펩티드 접합체 및 접합 방법
DE102016005550B4 (de) 2016-05-09 2024-09-26 Hans-Georg Rammensee Adjuvans zur lnduzierung einer zellulären lmmunantwort

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE785933A (fr) * 1971-07-07 1973-01-08 Ciba Geigy Procede de preparation de peptides contenant de la cystine
ZA735680B (en) * 1972-09-21 1974-07-31 Hoffmann La Roche Polypeptides
US4016259A (en) * 1974-07-26 1977-04-05 Research Corporation Contraceptive polypeptides
DE2860893D1 (en) * 1977-06-20 1981-11-05 Ciba Geigy Ag Lipopeptides, process for their preparation and pharmaceutical compositions containing them

Also Published As

Publication number Publication date
EP0014815A2 (de) 1980-09-03
US4439425A (en) 1984-03-27
EP0014815A3 (de) 1980-10-29
AU5399979A (en) 1980-06-26
JPS5585553A (en) 1980-06-27

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