DK539986A - Alfa-(aminoalkyl)-aryleddikesyre-derivater og fremgangsmaade til fremstilling deraf - Google Patents
Alfa-(aminoalkyl)-aryleddikesyre-derivater og fremgangsmaade til fremstilling derafInfo
- Publication number
- DK539986A DK539986A DK539986A DK539986A DK539986A DK 539986 A DK539986 A DK 539986A DK 539986 A DK539986 A DK 539986A DK 539986 A DK539986 A DK 539986A DK 539986 A DK539986 A DK 539986A
- Authority
- DK
- Denmark
- Prior art keywords
- aeric
- aminoal
- alfa
- cool
- procedures
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
- C07D295/182—Radicals derived from carboxylic acids
- C07D295/185—Radicals derived from carboxylic acids from aliphatic carboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/54—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/55—Acids; Esters
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/54—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/56—Amides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/54—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/57—Nitriles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D295/145—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/797,590 US4783537A (en) | 1985-11-13 | 1985-11-13 | α-(aminoalkyl)-arylacetic acid derivatives |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DK539986D0 DK539986D0 (da) | 1986-11-12 |
| DK539986A true DK539986A (da) | 1987-05-14 |
Family
ID=25171266
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK539986A DK539986A (da) | 1985-11-13 | 1986-11-12 | Alfa-(aminoalkyl)-aryleddikesyre-derivater og fremgangsmaade til fremstilling deraf |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US4783537A (da) |
| EP (1) | EP0222099A3 (da) |
| JP (1) | JPS62120349A (da) |
| AU (1) | AU596805B2 (da) |
| DE (1) | DE222099T1 (da) |
| DK (1) | DK539986A (da) |
| FI (1) | FI864615A (da) |
| IL (1) | IL80587A0 (da) |
| NO (1) | NO864525L (da) |
| NZ (1) | NZ217198A (da) |
| PH (1) | PH23211A (da) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4847301A (en) * | 1985-11-13 | 1989-07-11 | Pennwalt Corporation | Methods of use of α-(aminoalkyl)-arylacetic acid derivatives |
| DE3722007A1 (de) * | 1987-07-03 | 1989-01-12 | Hoechst Ag | Verfahren zur herstellung bicyclischer aminocarbonsaeuren, zwischenprodukte dieses verfahrens und deren verwendung |
| JP3429338B2 (ja) * | 1992-07-27 | 2003-07-22 | 杏林製薬株式会社 | 新規なアリールグリシンアミド誘導体及びその製造法 |
| US6232316B1 (en) | 1998-06-16 | 2001-05-15 | Targacept, Inc. | Methods for treatment of CNS disorders |
| US6455554B1 (en) | 1999-06-07 | 2002-09-24 | Targacept, Inc. | Oxopyridinyl pharmaceutical compositions and methods for use |
| JP2003501416A (ja) * | 1999-06-07 | 2003-01-14 | ターガセプト，インコーポレイテッド | 医薬組成物およびその使用法 |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL70757C (da) * | 1947-10-13 | |||
| US2776282A (en) * | 1954-05-04 | 1957-01-01 | Searle & Co | Cyclic amides of alpha-toluic acids and derivatives thereof |
| GB771814A (en) * | 1954-06-04 | 1957-04-03 | Pharmacia Ab | New butyryl amides and processes for their manufacture |
| US3078275A (en) * | 1956-05-28 | 1963-02-19 | Upjohn Co | N, n-disubstituted-alpha-(tertiaryaminoalkyl)-alpha, alpha-diphenylacetamides |
| US2854472A (en) * | 1956-12-24 | 1958-09-30 | Searle & Co | 4-dialkylamino-2-hydroxybenzyl-2-hydroxyphenylbutyronitrile, corresponding ethers, and amides |
| FR2485M (fr) * | 1961-05-17 | 1964-04-27 | Searle & Co | Nouveaux régulateurs cardiaques. |
| US3225054A (en) * | 1962-07-03 | 1965-12-21 | Searle & Co | 4-dipropylamino-2-aryl-2-pyridylalkanamides |
| US3254092A (en) * | 1964-07-17 | 1966-05-31 | Mcneilab Inc | Pyridyl propionitrile and pyridyl propionamide derivatives |
| US3528984A (en) * | 1967-05-19 | 1970-09-15 | Wyeth John & Brother Ltd | 1,2-diaryl butane derivatives |
| FR2273532A1 (fr) * | 1974-06-06 | 1976-01-02 | Synthelabo | Nouveaux derives du thienyl-2 acetonitrile, leurs sels, leur preparation et les medicaments qui en contiennent |
| US4225606A (en) * | 1975-09-23 | 1980-09-30 | Janssen Pharmaceutica N.V. | N-Aryl-N-(1-L-4-piperidinyl)arylacetamides |
| US4277471A (en) * | 1979-03-12 | 1981-07-07 | Eli Lilly And Company | 1,1-Biphenyl-2-yl alkylamines, formulations and antiarrhythmic treatment |
| FR2460920A1 (fr) * | 1979-07-13 | 1981-01-30 | Lafon Labor | Derives 2-substitues de 2-alkylaminomethyl-propionates, leur procede de preparation et leur utilisation en therapeutique |
| FR2467200A1 (fr) * | 1979-10-11 | 1981-04-17 | Clin Midy | Derives du pyrrole actifs sur les troubles du rythme cardiovasculaire |
| US4539316A (en) * | 1981-05-18 | 1985-09-03 | Bristol-Myers Company | Pyridine derivatives of 1,2-diaminocyclobutene-3,4-diones |
| JPS5980664A (ja) * | 1982-09-30 | 1984-05-10 | Fujisawa Pharmaceut Co Ltd | α−アリ−ル−α−ピリジル脂肪酸誘導体およびその製法 |
-
1985
- 1985-11-13 US US06/797,590 patent/US4783537A/en not_active Expired - Fee Related
-
1986
- 1986-08-13 NZ NZ217198A patent/NZ217198A/xx unknown
- 1986-08-14 AU AU61183/86A patent/AU596805B2/en not_active Expired - Fee Related
- 1986-09-10 DE DE198686112499T patent/DE222099T1/de active Pending
- 1986-09-10 EP EP86112499A patent/EP0222099A3/en not_active Withdrawn
- 1986-09-25 PH PH34287A patent/PH23211A/en unknown
- 1986-11-11 IL IL80587A patent/IL80587A0/xx unknown
- 1986-11-11 JP JP61266797A patent/JPS62120349A/ja active Pending
- 1986-11-12 FI FI864615A patent/FI864615A/fi not_active IP Right Cessation
- 1986-11-12 NO NO864525A patent/NO864525L/no unknown
- 1986-11-12 DK DK539986A patent/DK539986A/da not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| NZ217198A (en) | 1989-10-27 |
| IL80587A0 (en) | 1987-02-27 |
| AU6118386A (en) | 1987-05-21 |
| AU596805B2 (en) | 1990-05-17 |
| NO864525L (no) | 1987-05-14 |
| FI864615A0 (fi) | 1986-11-12 |
| DE222099T1 (de) | 1987-10-15 |
| PH23211A (en) | 1989-06-06 |
| FI864615A (fi) | 1987-05-14 |
| EP0222099A2 (en) | 1987-05-20 |
| US4783537A (en) | 1988-11-08 |
| EP0222099A3 (en) | 1989-01-25 |
| DK539986D0 (da) | 1986-11-12 |
| NO864525D0 (no) | 1986-11-12 |
| JPS62120349A (ja) | 1987-06-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| AHB | Application shelved due to non-payment |