DK532180A - Fremgangsmaade til fremstilling af acylpeptider eller salte eller komplekser deraf - Google Patents

Fremgangsmaade til fremstilling af acylpeptider eller salte eller komplekser deraf

Info

Publication number
DK532180A
DK532180A DK532180A DK532180A DK532180A DK 532180 A DK532180 A DK 532180A DK 532180 A DK532180 A DK 532180A DK 532180 A DK532180 A DK 532180A DK 532180 A DK532180 A DK 532180A
Authority
DK
Denmark
Prior art keywords
acylpeptides
complexes
salts
amino acids
amino group
Prior art date
Application number
DK532180A
Other languages
Danish (da)
English (en)
Inventor
H Rink
P Sieber
B Kamber
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of DK532180A publication Critical patent/DK532180A/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/06—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/655—Somatostatins
    • C07K14/6555—Somatostatins at least 1 amino acid in D-form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00—Peptide or protein sequence
    • Y10S930/01—Peptide or protein sequence
    • Y10S930/16—Somatostatin; related peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Analytical Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Endocrinology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DK532180A 1979-12-14 1980-12-12 Fremgangsmaade til fremstilling af acylpeptider eller salte eller komplekser deraf DK532180A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH1109679 1979-12-14

Publications (1)

Publication Number Publication Date
DK532180A true DK532180A (da) 1981-06-15

Family

ID=4370005

Family Applications (1)

Application Number Title Priority Date Filing Date
DK532180A DK532180A (da) 1979-12-14 1980-12-12 Fremgangsmaade til fremstilling af acylpeptider eller salte eller komplekser deraf

Country Status (18)

Country Link
US (1) US4369179A (enExample)
EP (1) EP0030920B1 (enExample)
JP (1) JPS5692850A (enExample)
KR (2) KR850000415B1 (enExample)
AT (1) ATE6251T1 (enExample)
AU (1) AU544256B2 (enExample)
CA (1) CA1161033A (enExample)
DD (1) DD154098A5 (enExample)
DE (1) DE3066654D1 (enExample)
DK (1) DK532180A (enExample)
ES (1) ES497696A0 (enExample)
FI (1) FI803849L (enExample)
GR (1) GR73621B (enExample)
IL (1) IL61696A0 (enExample)
NO (1) NO803757L (enExample)
NZ (1) NZ195817A (enExample)
PT (1) PT72191B (enExample)
ZA (1) ZA807796B (enExample)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE14226T1 (de) * 1981-12-24 1985-07-15 Ciba Geigy Ag Cyclische octapeptide und pharmazeutische praeparate davon, sowie verfahren zur herstellung derselben und ihre anwendung.
FR2522655B1 (fr) * 1982-03-05 1987-03-06 Sanofi Sa Analogues de la somatostatine possedant une liaison du type hydrazide et medicaments en contenant
DE3379657D1 (en) * 1982-12-06 1989-05-24 Merck & Co Inc Dicyclic hexapeptides, processes for their preparation and pharmaceutical compositions containing them
US4485101A (en) * 1983-10-11 1984-11-27 Administrators Of The Tulane Educational Fund Peptides
US4612302A (en) * 1983-11-14 1986-09-16 Brigham And Women's Hospital Clinical use of somatostatin analogues
US4650787A (en) * 1985-04-25 1987-03-17 Schally Andrew Victor Biologically active octapeptides
US5633263A (en) * 1989-04-26 1997-05-27 The Administrators Of The Tulane Educational Fund Linear somatostatin analogs
KR0173119B1 (ko) * 1989-04-26 1999-02-01 닐 에이. 밴스로우 선형 소마토스타틴 유사체
US5504069A (en) * 1993-02-11 1996-04-02 Biomeasure, Inc. Inhibition of trauma-induced tumor growth
US5597894A (en) * 1995-06-05 1997-01-28 The Louisiana State University Medical Center Foundation Multi-tyrosinated somatostatin analogs
US5905140A (en) * 1996-07-11 1999-05-18 Novo Nordisk A/S, Novo Alle Selective acylation method
US6355613B1 (en) * 1996-07-31 2002-03-12 Peptor Limited Conformationally constrained backbone cyclized somatostatin analogs
PT980253E (pt) * 1997-05-13 2004-08-31 Conseils De Rec Appl Scient S Somatostatina e agonistas de somatostatina para tratar a insensibilidade a insulina e a sindrome x
WO1998051330A1 (en) * 1997-05-13 1998-11-19 Societe De Conseils De Recherches Et D'applications Scientifiques S.A. (S.C.R.A.S.) Method and compositions for treating hyperlipidemia and other conditions
ES2202864T3 (es) 1997-05-13 2004-04-01 Societe De Conseils De Recherches Et D'applications Scientifiques S.A.S. Agonistas de la somatostatina para disminuir el peso corporal.
US6004928A (en) * 1997-05-13 1999-12-21 Biomeasure, Incorporated Method of treating hyperlipidemia
US5968903A (en) * 1998-05-07 1999-10-19 Biomeasure, Incorporated Inhibition of H. pylori proliferation
CN1454214A (zh) * 2000-08-02 2003-11-05 赛莱技术公司 具有增高功效的修饰生物肽
ATE424414T1 (de) 2001-06-08 2009-03-15 Sod Conseils Rech Applic Chimere somatostatin-dopamin-analoga
CN101791409A (zh) 2003-04-22 2010-08-04 研究及应用科学协会股份有限公司 肽载体
ES2750651T3 (es) 2008-06-12 2020-03-26 Ipsen Bioinnovation Ltd Proteínas de fusión para uso en el tratamiento de acromegalia
US10240138B2 (en) 2008-06-12 2019-03-26 Ipsen Bioinnovation Limited Polypeptides that bind to and inhibit secretion from growth hormone secreting cells
GB0820970D0 (en) 2008-11-17 2008-12-24 Syntaxin Ltd Suppression of cancer
DK3007704T3 (da) 2013-06-13 2021-03-29 Antisense Therapeutics Ltd Kombinationsterapi til akromegali

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3944590A (en) * 1967-01-25 1976-03-16 Ciba-Geigy Corporation Process for the temporary protection of amino groups in peptide syntheses
US3875207A (en) * 1967-01-25 1975-04-01 Ciba Geigy Corp Process for the temporary protection of amino groups in peptide syntheses
US3725380A (en) * 1969-04-05 1973-04-03 Hoechst Ag Method of synthesizing peptides in the presence of a carbodiimide and a 1-hydroxy-benzotriazole
CH517705A (de) * 1969-12-16 1972-01-15 Ciba Geigy Ag Verfahren zur Herstellung von Cystin-haltigen Peptiden
DE2202613C3 (de) * 1972-01-20 1974-06-20 Farbwerke Hoechst Ag, Vormals Meister Lucius & Bruening, 6000 Frankfurt Verfahren zur Herstellung von Peptiden
CH577464A5 (enExample) * 1972-09-22 1976-07-15 Ciba Geigy Ag
US3882098A (en) * 1974-01-03 1975-05-06 American Home Prod Synthesis of des-Ala{hu 1{b , Gly{hu 2{b , Asn{hu 5{b -SRIF and intermediates
US4113714A (en) * 1975-01-03 1978-09-12 American Home Products Corporation [Des-Ala1, Gly2 -desamino-Cys3 ]somatostatin
US4130554A (en) * 1975-04-08 1978-12-19 Merck & Co., Inc. Process for preparing somatostatin analog
US4000259A (en) * 1975-06-16 1976-12-28 American Home Products Corporation Cyclic dodecapeptide analogs of somatostatin and intermediates
US3988304A (en) * 1975-08-25 1976-10-26 American Home Products Corporation Cyclic dodecapeptide derivatives of somatostatin and intermediates thereof
CA1083143A (en) * 1976-01-02 1980-08-05 Nedumparambil A. Abraham Carba derivatives of somatostatin and process therefor
US4062816A (en) * 1976-03-11 1977-12-13 Eli Lilly And Company D-Ala5 -somatostatin and intermediates thereto
US4098782A (en) * 1977-03-14 1978-07-04 American Home Products Corporation (His5)-somatostatin and analogues thereof
US4118380A (en) * 1977-07-25 1978-10-03 Ayerst, Mckenna & Harrison Limited Decapeptide analogs of somatostatin
US4115554A (en) * 1977-08-29 1978-09-19 Merck & Co., Inc. Somatostatin analogs
LU78191A1 (de) * 1977-09-28 1979-05-25 Ciba Geigy Ag Verfahren zur herstellung von neuen cyclopeptiden
US4140767A (en) * 1977-12-01 1979-02-20 Merck & Co., Inc. Somatostatin analogs
US4202802A (en) * 1978-10-02 1980-05-13 Eli Lilly And Company Peptides related to somatostatin
US4191754A (en) * 1979-02-28 1980-03-04 Merck & Co., Inc. Bicyclic somatostatin analogs
US4235886A (en) * 1979-10-31 1980-11-25 Merck & Co., Inc. Cyclic hexapeptide somatostatin analogs

Also Published As

Publication number Publication date
NZ195817A (en) 1984-07-06
DD154098A5 (de) 1982-02-24
AU544256B2 (en) 1985-05-23
FI803849A7 (fi) 1981-06-15
ATE6251T1 (de) 1984-03-15
CA1161033A (en) 1984-01-24
IL61696A0 (en) 1981-01-30
EP0030920B1 (de) 1984-02-15
FI803849L (fi) 1981-06-15
ES8200861A1 (es) 1981-11-16
NO803757L (no) 1981-06-15
PT72191A (de) 1981-01-01
PT72191B (de) 1982-01-13
EP0030920A3 (en) 1981-11-04
ES497696A0 (es) 1981-11-16
JPS5692850A (en) 1981-07-27
EP0030920A2 (de) 1981-06-24
DE3066654D1 (en) 1984-03-22
US4369179A (en) 1983-01-18
GR73621B (enExample) 1984-03-26
KR850000414B1 (ko) 1985-03-26
KR850000415B1 (ko) 1985-03-26
AU6534580A (en) 1981-06-18
KR830004216A (ko) 1983-07-06
ZA807796B (en) 1982-01-27

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