DK474582A - 6-fluor-3-(3-(1-heterocyclo)propyl)-1,2-benzisoxazoler, fremgangsmaade til fremstilling heraf, farmaceutiske praeparater heraf og deres anvendelse som laegemidler - Google Patents

6-fluor-3-(3-(1-heterocyclo)propyl)-1,2-benzisoxazoler, fremgangsmaade til fremstilling heraf, farmaceutiske praeparater heraf og deres anvendelse som laegemidler Download PDF

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Publication number
DK474582A
DK474582A DK474582A DK474582A DK474582A DK 474582 A DK474582 A DK 474582A DK 474582 A DK474582 A DK 474582A DK 474582 A DK474582 A DK 474582A DK 474582 A DK474582 A DK 474582A
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DK
Denmark
Prior art keywords
fluoro
heterocyclo
benzisoxazoles
propyl
procedures
Prior art date
Application number
DK474582A
Other languages
Danish (da)
English (en)
Inventor
Larry Davis
Joseph Thomas Klein
Original Assignee
Hoechst Roussel Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Roussel Pharma filed Critical Hoechst Roussel Pharma
Publication of DK474582A publication Critical patent/DK474582A/da

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
    • C07D261/20—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings condensed with carbocyclic rings or ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/10—Spiro-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
DK474582A 1982-04-09 1982-10-26 6-fluor-3-(3-(1-heterocyclo)propyl)-1,2-benzisoxazoler, fremgangsmaade til fremstilling heraf, farmaceutiske praeparater heraf og deres anvendelse som laegemidler DK474582A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/366,245 US4458075A (en) 1982-04-09 1982-04-09 6-Fluoro-3-[3-(1-heterocyclo)propyl]-1,2-benzisoxazoles

Publications (1)

Publication Number Publication Date
DK474582A true DK474582A (da) 1983-10-10

Family

ID=23442245

Family Applications (1)

Application Number Title Priority Date Filing Date
DK474582A DK474582A (da) 1982-04-09 1982-10-26 6-fluor-3-(3-(1-heterocyclo)propyl)-1,2-benzisoxazoler, fremgangsmaade til fremstilling heraf, farmaceutiske praeparater heraf og deres anvendelse som laegemidler

Country Status (18)

Country Link
US (1) US4458075A (fr)
EP (1) EP0091512B1 (fr)
JP (1) JPS58177981A (fr)
AT (1) ATE34172T1 (fr)
AU (1) AU560513B2 (fr)
CA (1) CA1189858A (fr)
DE (1) DE3278472D1 (fr)
DK (1) DK474582A (fr)
ES (1) ES516828A0 (fr)
FI (1) FI823434L (fr)
GR (1) GR77705B (fr)
HU (1) HU191076B (fr)
IL (1) IL66868A (fr)
NO (1) NO823557L (fr)
NZ (1) NZ202045A (fr)
PH (1) PH18365A (fr)
PT (1) PT75728B (fr)
ZA (1) ZA827814B (fr)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4894461A (en) * 1981-04-27 1990-01-16 Hoechst-Roussel Pharmaceuticals, Inc. 3-(γ-chloropropyl)-6-fluoro-1,2-benzisoxazole
US4980365A (en) * 1987-07-13 1990-12-25 Hoechst-Roussel Pharmaceuticals Inc. N-substituted-5,6-dimethoxy-1,2-benzisoxazole-3-propanamine and related compounds as analgesic and hypotensive agents
US4914204A (en) * 1988-03-14 1990-04-03 Hoechst-Roussel Pharmaceuticals Incorporated 4-Pentafluorophenoxypiperidines
US4954511A (en) * 1988-03-14 1990-09-04 Hoechst-Roussell Pharmaceuticals Inc. 4-pentafluorophenoxypiperidines
US4861889A (en) * 1988-03-14 1989-08-29 Hoechst-Roussel Pharmaceuticals, Inc. 3-(2,3,4,5,6-pentafluorophenoxy)-8-azabicyclo[3.2.1]octanes
US5114936A (en) * 1990-08-23 1992-05-19 Hoechst-Roussel Pharmaceuticals Incorporated 6,7-dihydro-3-phenyl-1,2-benzisoxazol-4(5h)-ones and -ols, compositions and pharmaceutical use
US5750542A (en) 1993-09-28 1998-05-12 Pfizer Benzisoxazole and benzisothizole derivatives as cholinesterase inhibitors
EP1535912A1 (fr) * 2000-04-28 2005-06-01 Arcadia Pharmaceuticals Inc. Agonistes muscariniques
JP4119126B2 (ja) 2000-04-28 2008-07-16 アカディア ファーマシューティカルズ，インコーポレーテッド ムスカリン性アゴニスト
DE102019103847A1 (de) 2019-02-15 2020-08-20 Vetron Typical Europe Gmbh Nähmaschine

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS4970963A (fr) * 1972-11-09 1974-07-09
GB1488003A (en) * 1973-10-23 1977-10-05 Lilly Industries Ltd 1,2-benzisoxazole derivatives processes for their preparation and their use as pharmaceuticals
FI60390C (fi) * 1975-03-05 1982-01-11 Sumitomo Chemical Co Foerfarande foer framstaellning av neuroleptiska butyrofenoner
JPS51136666A (en) * 1975-05-19 1976-11-26 Dainippon Pharmaceut Co Ltd Process for preparing 3-aminoalkyl-1,2-benzisoxazole derivatives.
JPS6043064B2 (ja) * 1979-11-28 1985-09-26 ウェルファイド株式会社 新規イソオキサゾ−ル誘導体

Also Published As

Publication number Publication date
DE3278472D1 (en) 1988-06-16
CA1189858A (fr) 1985-07-02
NO823557L (no) 1983-10-10
IL66868A0 (en) 1982-12-31
PH18365A (en) 1985-06-13
IL66868A (en) 1987-07-31
PT75728B (en) 1985-11-11
EP0091512B1 (fr) 1988-05-11
AU8977782A (en) 1983-10-13
GR77705B (fr) 1984-09-25
US4458075A (en) 1984-07-03
ZA827814B (en) 1983-08-31
ES8308560A1 (es) 1983-09-16
EP0091512A2 (fr) 1983-10-19
ATE34172T1 (de) 1988-05-15
AU560513B2 (en) 1987-04-09
JPS58177981A (ja) 1983-10-18
EP0091512A3 (en) 1984-12-12
FI823434A0 (fi) 1982-10-08
ES516828A0 (es) 1983-09-16
PT75728A (en) 1982-11-01
HU191076B (en) 1987-01-28
FI823434L (fi) 1983-10-10
NZ202045A (en) 1986-03-14

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AHS Application shelved for other reasons than non-payment