DK470488D0 - Piperidinderivater, og farmaceutiske praeparater m od arrhytmi med indhold af saadanne - Google Patents

Piperidinderivater, og farmaceutiske praeparater m od arrhytmi med indhold af saadanne

Info

Publication number
DK470488D0
DK470488D0 DK470488A DK470488A DK470488D0 DK 470488 D0 DK470488 D0 DK 470488D0 DK 470488 A DK470488 A DK 470488A DK 470488 A DK470488 A DK 470488A DK 470488 D0 DK470488 D0 DK 470488D0
Authority
DK
Denmark
Prior art keywords
arrhythmy
contents
pharmaceutical preparations
piperidin derivatives
piperidin
Prior art date
Application number
DK470488A
Other languages
English (en)
Other versions
DK470488A (da
Inventor
Hitoshi Oinuma
Motosuke Yamanaka
Kazutoshi Miyake
Tomonori Hoshiko
Norio Minami
Tadao Shoji
Yoshiharu Daiku
Kohei Sawada
Kenichi Nomoto
Original Assignee
Eisai Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP20972687A external-priority patent/JP2637989B2/ja
Priority claimed from JP62209728A external-priority patent/JP2584454B2/ja
Priority claimed from JP20972787A external-priority patent/JPH0819083B2/ja
Application filed by Eisai Co Ltd filed Critical Eisai Co Ltd
Publication of DK470488D0 publication Critical patent/DK470488D0/da
Publication of DK470488A publication Critical patent/DK470488A/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/10—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with radicals containing only carbon and hydrogen atoms attached to ring carbon atoms
    • C07D211/14—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with radicals containing only carbon and hydrogen atoms attached to ring carbon atoms with hydrocarbon or substituted hydrocarbon radicals attached to the ring nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/30—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by doubly bound oxygen or sulfur atoms or by two oxygen or sulfur atoms singly bound to the same carbon atom
    • C07D211/32—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by doubly bound oxygen or sulfur atoms or by two oxygen or sulfur atoms singly bound to the same carbon atom by oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/54—Sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/36—Radicals substituted by singly-bound nitrogen atoms
    • C07D213/38—Radicals substituted by singly-bound nitrogen atoms having only hydrogen or hydrocarbon radicals attached to the substituent nitrogen atom

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
DK470488A 1987-08-24 1988-08-23 Piperidinderivater, og farmaceutiske praeparater m od arrhytmi med indhold af saadanne DK470488A (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP20972687A JP2637989B2 (ja) 1987-08-24 1987-08-24 ピペリジン誘導体及びそれを含有する不整脈治療・予防剤
JP62209728A JP2584454B2 (ja) 1987-08-24 1987-08-24 ピペリジン誘導体及びそれを含有する不整脈治療・予防剤
JP20972787A JPH0819083B2 (ja) 1987-08-24 1987-08-24 スルホンアミド誘導体及びそれを含有する不整脈治療・予防剤

Publications (2)

Publication Number Publication Date
DK470488D0 true DK470488D0 (da) 1988-08-23
DK470488A DK470488A (da) 1989-02-25

Family

ID=27329045

Family Applications (1)

Application Number Title Priority Date Filing Date
DK470488A DK470488A (da) 1987-08-24 1988-08-23 Piperidinderivater, og farmaceutiske praeparater m od arrhytmi med indhold af saadanne

Country Status (11)

Country Link
US (2) US4977165A (da)
EP (1) EP0304888B1 (da)
KR (1) KR910002581B1 (da)
CA (1) CA1263658A (da)
DE (1) DE3875866T2 (da)
DK (1) DK470488A (da)
ES (1) ES2045044T3 (da)
GR (1) GR3006380T3 (da)
HU (1) HU207043B (da)
NO (1) NO883750L (da)
PH (1) PH25458A (da)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4906634A (en) * 1988-03-08 1990-03-06 Schering A.G. Novel N-[4-(aminosubstituted)phenyl]methanesulfonamides and their use as cardiovascular agents
JP3065659B2 (ja) * 1989-07-25 2000-07-17 ファルマシア・アンド・アップジョン・カンパニー 抗不整脈性第三級アミン―アルケニル―フェニル―アルカンスルホンアミド
US5405997A (en) * 1989-07-25 1995-04-11 The Upjohn Company Antiarrhythmic methanesulfonamides
ES2096651T3 (es) * 1990-06-07 1997-03-16 Merrell Pharma Inc Derivados de 1-piperidinil alcanoilarilsulfonamida.
US5478846A (en) * 1990-06-07 1995-12-26 Merrell Dow Pharmaceuticals Inc. 1-piperidinyl alkanoylanyl sulfonamides for treatment of cardiac arrhythmia
NZ239846A (en) * 1990-09-27 1994-11-25 Merck & Co Inc Sulphonamide derivatives and pharmaceutical compositions thereof
US5202346A (en) * 1992-02-25 1993-04-13 American Home Products Corporation Piperidinyl and piperazinyl derivatives
US5254689A (en) * 1992-02-25 1993-10-19 American Home Products Corporation Piperdinyl and piperazinyl derivatives
WO1999038827A1 (en) * 1998-02-02 1999-08-05 Merck & Co., Inc. PLATELET AGGREGATION INHIBITION USING LOW MOLECULAR WEIGHT HEPARIN IN COMBINATION WITH A GP IIb/IIIa ANTAGONIST
US6136794A (en) * 1998-02-02 2000-10-24 Merck & Co., Inc. Platelet aggregation inhibition using low molecular weight heparin in combination with a GP IIb/IIIa antagonist
GB9901147D0 (en) * 1999-01-19 1999-03-10 Merck Sharp & Dohme Therapeutic agents
DE10000739A1 (de) * 2000-01-11 2001-07-12 Merck Patent Gmbh Piperidin- und Piperazinderivate
US7408067B2 (en) 2002-01-17 2008-08-05 Merck + Co., Inc. Aza-cyclic compounds as modulators of acetylcholine receptors
GB0326221D0 (en) 2003-11-10 2003-12-17 Merck Sharp & Dohme Therapeutic agents,compositions,preparations and uses
GB0419192D0 (en) * 2004-08-27 2004-09-29 Merck Sharp & Dohme Therapeutic agents
GB0426313D0 (en) * 2004-12-01 2005-01-05 Merck Sharp & Dohme Therapeutic agents
US9051296B2 (en) 2009-11-16 2015-06-09 Raqualia Pharma Inc. Aryl carboxamide derivatives as TTX-S blockers
WO2015040352A1 (en) * 2013-09-18 2015-03-26 Redx Pharma Limited Agricultural chemicals

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB993584A (da) * 1962-01-24
US3968242A (en) * 1974-08-26 1976-07-06 Mead Johnson & Company Sulfonamidoaminopropiophenone interceptive process
US4044150A (en) * 1976-06-18 1977-08-23 Mead Johnson & Company Antihypertensive 4'-[1-hydroxy-2-[(1-phenoxy ethyl)-amino]ethyl]methanesulfonanilide and salts thereof and therapeutic use
DE3306697A1 (de) * 1983-02-25 1984-08-30 Bayer Ag, 5090 Leverkusen Substituierte maleinsaeureimide
US4544654A (en) * 1984-03-20 1985-10-01 Schering A.G. Substituted sulfonamidobenzamides, antiarrhythmic agents and compositions thereof
PH23283A (en) * 1986-02-26 1989-06-30 Eisai Co Ltd Piperidine derivative, pharmaceutical composition containing the same and method of use thereof

Also Published As

Publication number Publication date
GR3006380T3 (da) 1993-06-21
PH25458A (en) 1991-07-01
DE3875866D1 (de) 1992-12-17
CA1263658A (en) 1989-12-05
HU207043B (en) 1993-03-01
US5082850A (en) 1992-01-21
NO883750D0 (no) 1988-08-22
HUT48587A (en) 1989-06-28
EP0304888A1 (en) 1989-03-01
KR890003691A (ko) 1989-04-17
US4977165A (en) 1990-12-11
DE3875866T2 (de) 1993-04-15
DK470488A (da) 1989-02-25
ES2045044T3 (es) 1994-01-16
EP0304888B1 (en) 1992-11-11
NO883750L (no) 1989-02-27
KR910002581B1 (ko) 1991-04-27

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Legal Events

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AHB Application shelved due to non-payment