DK45981A - Fremgangsmaade til fremstilling af pyrononer og de tilsvarende hydroxysyrer - Google Patents

Fremgangsmaade til fremstilling af pyrononer og de tilsvarende hydroxysyrer

Info

Publication number
DK45981A
DK45981A DK45981A DK45981A DK45981A DK 45981 A DK45981 A DK 45981A DK 45981 A DK45981 A DK 45981A DK 45981 A DK45981 A DK 45981A DK 45981 A DK45981 A DK 45981A
Authority
DK
Denmark
Prior art keywords
pyronones
preparing
procedure
hydroxy acids
similar hydroxy
Prior art date
Application number
DK45981A
Other languages
English (en)
Inventor
A A Patchett
C H Kuo
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of DK45981A publication Critical patent/DK45981A/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/16—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D309/28—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/30—Oxygen atoms, e.g. delta-lactones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
    • A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
DK45981A 1980-02-04 1981-02-03 Fremgangsmaade til fremstilling af pyrononer og de tilsvarende hydroxysyrer DK45981A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US11805080A 1980-02-04 1980-02-04

Publications (1)

Publication Number Publication Date
DK45981A true DK45981A (da) 1981-08-05

Family

ID=22376236

Family Applications (1)

Application Number Title Priority Date Filing Date
DK45981A DK45981A (da) 1980-02-04 1981-02-03 Fremgangsmaade til fremstilling af pyrononer og de tilsvarende hydroxysyrer

Country Status (9)

Country Link
EP (1) EP0033537B1 (da)
JP (1) JPS56122374A (da)
AT (1) ATE13534T1 (da)
DE (1) DE3170666D1 (da)
DK (1) DK45981A (da)
ES (1) ES8202550A1 (da)
GR (1) GR73077B (da)
IE (1) IE51477B1 (da)
PT (1) PT72394B (da)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2739768A (en) * 1954-09-27 1956-03-27 August C Purpura Aircraft having feathering airfoils

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU548996B2 (en) 1980-02-04 1986-01-09 Merck & Co., Inc. Tetrahydro-2h-pyran-2-one derivatives
JPH0692381B2 (ja) * 1980-03-31 1994-11-16 三共株式会社 Ｍｂ−５３０ａ誘導体
JPS57185274A (en) * 1981-05-07 1982-11-15 Sankyo Co Ltd Tetrahydro-mb-530b and its derivative
JPS57185276A (en) * 1981-05-11 1982-11-15 Sankyo Co Ltd Dihydro-dum-4 and dihydro-isodum-4 and their derivative
EP0137445B1 (en) * 1983-10-11 1990-01-03 Merck & Co. Inc. Process for c-methylation of 2-methylbutyrates
EP0137444B1 (en) * 1983-10-11 1990-01-31 Merck & Co. Inc. Processes for preparing 6(R)-[2-[8(S)(2,2-dimethylbutyryloxy)-2(S),6(S)-dimethyl-1,2,3,4,4a(S),5,6,7,8,8a(S)-Decahydronaphthyl-1(S)]ethyl]-4(R)-hydroxy-3,4,5,6-tetrahydro-2H-pyran-2-one
US4885314A (en) * 1987-06-29 1989-12-05 Merck & Co., Inc. Novel HMG-CoA reductase inhibitors
DE3884536T2 (de) * 1987-09-03 1994-04-28 Merck & Co Inc Hydrierverfahren zur Bildung von Di- oder Tetrahydro-HMG-CoA-Reduktase-Inhibitoren.
US5089523A (en) * 1990-05-11 1992-02-18 E. R. Squibb & Sons, Inc. Fluorinated derivatives of mevinic acids
US5250435A (en) * 1991-06-04 1993-10-05 Merck & Co., Inc. Mutant strains of Aspergillus terreus for producing 7-[1,2,6,7,8,8a(R)-hexa-hydro-2(S),6(R)-dimethyl-8(S)-hydroxy-1(S)-naphthyl]-3(R),5(R)-dihydroxyheptanoic acid (triol acid),I)
PT1007033E (pt) * 1997-08-28 2008-07-22 Novartis Ag Antagonistas do antigénio-1 da função de linfócitos

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4049495A (en) * 1974-06-07 1977-09-20 Sankyo Company Limited Physiologically active substances and fermentative process for producing the same
JPS5612114B2 (da) * 1974-06-07 1981-03-18
JPS6026094B2 (ja) * 1978-07-04 1985-06-21 三共株式会社 テトラヒドロｍｌ↓−２３６ｂおよびその誘導体並びにそれを有効成分とする高脂血症治療剤
JPS5925599B2 (ja) * 1979-02-20 1984-06-19 三共株式会社 新生理活性物質モナコリンｋおよびその製造法
US4231938A (en) * 1979-06-15 1980-11-04 Merck & Co., Inc. Hypocholesteremic fermentation products and process of preparation
IL60219A (en) * 1979-06-15 1985-05-31 Merck & Co Inc Hypocholesteremic fermentation products of the hmg-coa reductase inhibitor type,their preparation and pharmaceutical compositions containing them

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2739768A (en) * 1954-09-27 1956-03-27 August C Purpura Aircraft having feathering airfoils

Also Published As

Publication number Publication date
JPH0136471B2 (da) 1989-07-31
EP0033537A2 (en) 1981-08-12
ES499078A0 (es) 1982-02-01
EP0033537A3 (en) 1982-02-24
GR73077B (da) 1984-01-31
PT72394B (en) 1982-09-06
ES8202550A1 (es) 1982-02-01
ATE13534T1 (de) 1985-06-15
IE810168L (en) 1981-08-04
IE51477B1 (en) 1987-01-07
EP0033537B1 (en) 1985-05-29
PT72394A (en) 1981-02-01
JPS56122374A (en) 1981-09-25
DE3170666D1 (en) 1985-07-04

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Legal Events

Date Code Title Description
AHB Application shelved due to non-payment