DK451389A - 2-substituerede 4,5-diaryl-thioimidazoler samt farmaceutisk praeparat indeholdende saadanne forbindelser - Google Patents
2-substituerede 4,5-diaryl-thioimidazoler samt farmaceutisk praeparat indeholdende saadanne forbindelser Download PDFInfo
- Publication number
- DK451389A DK451389A DK451389A DK451389A DK451389A DK 451389 A DK451389 A DK 451389A DK 451389 A DK451389 A DK 451389A DK 451389 A DK451389 A DK 451389A DK 451389 A DK451389 A DK 451389A
- Authority
- DK
- Denmark
- Prior art keywords
- thioimidazoles
- diaryl
- substituted
- compounds
- pharmaceutical preparations
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D233/28—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/30—Oxygen or sulfur atoms
- C07D233/42—Sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/84—Sulfur atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US07/244,170 US4900744A (en) | 1988-09-14 | 1988-09-14 | Antihypercholesterolemic 4,5-diaryl-2-substituted thioimidazoles |
Publications (2)
Publication Number | Publication Date |
---|---|
DK451389D0 DK451389D0 (da) | 1989-09-13 |
DK451389A true DK451389A (da) | 1990-03-15 |
Family
ID=22921646
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK451389A DK451389A (da) | 1988-09-14 | 1989-09-13 | 2-substituerede 4,5-diaryl-thioimidazoler samt farmaceutisk praeparat indeholdende saadanne forbindelser |
Country Status (13)
Country | Link |
---|---|
US (1) | US4900744A (de) |
EP (1) | EP0359197B1 (de) |
JP (1) | JPH02174762A (de) |
KR (1) | KR900004697A (de) |
AT (1) | ATE83772T1 (de) |
AU (1) | AU615572B2 (de) |
DE (1) | DE68904018T2 (de) |
DK (1) | DK451389A (de) |
ES (1) | ES2053896T3 (de) |
GR (1) | GR3006839T3 (de) |
IL (1) | IL91620A0 (de) |
NZ (1) | NZ230624A (de) |
ZA (1) | ZA897022B (de) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5290814A (en) * | 1988-11-21 | 1994-03-01 | Burroughs Wellcome Co. | Anti-atherosclerotic diaryl compounds |
JPH05502235A (ja) * | 1989-12-12 | 1993-04-22 | ローン―プーラン・サント | イミダゾール類 |
MX9203711A (es) * | 1990-01-12 | 1992-07-01 | Rhone Poulenc Rorer Sa | Derivados de imidazol y composiciones farmaceuticas que los contienen. |
US5011851A (en) * | 1990-02-13 | 1991-04-30 | Bristol-Myers Squibb Co. | Imidazole carboxylic acids and esters and inhibition of blood platelet aggregation therewith |
GB9019838D0 (en) * | 1990-09-11 | 1990-10-24 | Smith Kline French Lab | Compounds |
US5179117A (en) * | 1991-12-20 | 1993-01-12 | Du Pont Merck Pharmaceutical Company | Antihypercholesterolemic 2-substituted imidazoles |
US5364875A (en) * | 1992-05-11 | 1994-11-15 | The Du Pont Merck Pharmaceutical Company | Imidazoles linked to bicyclic heterocyclic groups for the treatment of atherosclerosis |
US5310748A (en) * | 1992-05-11 | 1994-05-10 | The Du Pont Merck Pharmaceutical Company | Imidazoles for the treatment of atherosclerosis |
AU5322494A (en) | 1992-10-02 | 1994-04-26 | Trustees Of Dartmouth College | Bispecific reagents for redirected targeting of low density lipoprotein |
US5491152A (en) * | 1994-03-23 | 1996-02-13 | The Du Pont Merck Pharmaceutical Company | Derivatives of cyclic ethers and sulfides for the treatment of atherosclerosis |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US465438A (en) * | 1891-12-15 | Alcide frangois trouard | ||
US3636003A (en) * | 1969-11-17 | 1972-01-18 | Geigy Chem Corp | Substituted 2-mercaptoimidazole derivatives |
DE2823197A1 (de) * | 1978-05-24 | 1979-11-29 | Schering Ag | Neue imidazolderivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate |
DE3228271A1 (de) * | 1982-07-29 | 1984-02-02 | A. Nattermann & Cie GmbH, 5000 Köln | Triphenylimidazolyloxyalkansaeuren und ihre derivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate |
DE3323870A1 (de) * | 1983-07-02 | 1985-01-03 | A. Nattermann & Cie GmbH, 5000 Köln | Neue imidazol-2-ylthioalkansaeuren und ihre derivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate |
ZA854550B (en) * | 1984-06-18 | 1986-04-30 | Smithkline Beckman Corp | Leukotriene antagonists |
US4743613A (en) * | 1986-04-08 | 1988-05-10 | Smithkline Beckman Corporation | Ester prodrugs of dopamine-β-hydroxylase, inhibitors, composition containing them, and method of using them to inhibit dopamine-β-hydroxylase activity |
US4734421A (en) * | 1986-10-29 | 1988-03-29 | Merck & Co., Inc. | Anti-inflammatory substituted 2-benzyl-mercapto-imidazole and pyrimidine derivatives compositions and method of use therefor |
US4935438A (en) * | 1987-12-29 | 1990-06-19 | Smithkline Beckman Corporation | Dopamine-β-hydroxylase inhibitors |
-
1988
- 1988-09-14 US US07/244,170 patent/US4900744A/en not_active Expired - Lifetime
-
1989
- 1989-09-12 DE DE8989116858T patent/DE68904018T2/de not_active Expired - Fee Related
- 1989-09-12 NZ NZ230624A patent/NZ230624A/en unknown
- 1989-09-12 AT AT89116858T patent/ATE83772T1/de active
- 1989-09-12 EP EP89116858A patent/EP0359197B1/de not_active Expired - Lifetime
- 1989-09-12 KR KR1019890013199A patent/KR900004697A/ko not_active Application Discontinuation
- 1989-09-12 ES ES89116858T patent/ES2053896T3/es not_active Expired - Lifetime
- 1989-09-13 DK DK451389A patent/DK451389A/da not_active Application Discontinuation
- 1989-09-13 IL IL91620A patent/IL91620A0/xx unknown
- 1989-09-14 ZA ZA897022A patent/ZA897022B/xx unknown
- 1989-09-14 AU AU41361/89A patent/AU615572B2/en not_active Ceased
- 1989-09-14 JP JP1237384A patent/JPH02174762A/ja active Pending
-
1993
- 1993-01-21 GR GR930400090T patent/GR3006839T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
NZ230624A (en) | 1991-06-25 |
ATE83772T1 (de) | 1993-01-15 |
ZA897022B (en) | 1991-05-29 |
JPH02174762A (ja) | 1990-07-06 |
IL91620A0 (en) | 1990-04-29 |
DE68904018T2 (de) | 1993-04-29 |
EP0359197B1 (de) | 1992-12-23 |
KR900004697A (ko) | 1990-04-12 |
DK451389D0 (da) | 1989-09-13 |
EP0359197A1 (de) | 1990-03-21 |
US4900744A (en) | 1990-02-13 |
DE68904018D1 (de) | 1993-02-04 |
GR3006839T3 (de) | 1993-06-30 |
AU4136189A (en) | 1990-03-22 |
ES2053896T3 (es) | 1994-08-01 |
AU615572B2 (en) | 1991-10-03 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
AHB | Application shelved due to non-payment |