DK44688A - Beta-alkylmelatoniner, fremgangsmaade til fremstilling deraf og mellemprodukter til brug ved fremgangsmaaden - Google Patents

Beta-alkylmelatoniner, fremgangsmaade til fremstilling deraf og mellemprodukter til brug ved fremgangsmaaden

Info

Publication number
DK44688A
DK44688A DK044688A DK44688A DK44688A DK 44688 A DK44688 A DK 44688A DK 044688 A DK044688 A DK 044688A DK 44688 A DK44688 A DK 44688A DK 44688 A DK44688 A DK 44688A
Authority
DK
Denmark
Prior art keywords
beta
melatonines
intermediates
procedures
alkyl
Prior art date
Application number
DK044688A
Other languages
Danish (da)
English (en)
Other versions
DK44688D0 (da
Inventor
Michael Edward Flaugh
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of DK44688D0 publication Critical patent/DK44688D0/da
Publication of DK44688A publication Critical patent/DK44688A/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • C07D209/16—Tryptamines

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Indole Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DK044688A 1987-02-02 1988-01-29 Beta-alkylmelatoniner, fremgangsmaade til fremstilling deraf og mellemprodukter til brug ved fremgangsmaaden DK44688A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US1025987A 1987-02-02 1987-02-02

Publications (2)

Publication Number Publication Date
DK44688D0 DK44688D0 (da) 1988-01-29
DK44688A true DK44688A (da) 1988-08-03

Family

ID=21744889

Family Applications (2)

Application Number Title Priority Date Filing Date
DK044688D DK168434B1 (da) 1987-02-02 1988-01-29 Beta-alkylmelatoniner, fremgangsmåde til fremstilling deraf samt farmaceutiske præparater indeholdende disse forbindelser
DK044688A DK44688A (da) 1987-02-02 1988-01-29 Beta-alkylmelatoniner, fremgangsmaade til fremstilling deraf og mellemprodukter til brug ved fremgangsmaaden

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DK044688D DK168434B1 (da) 1987-02-02 1988-01-29 Beta-alkylmelatoniner, fremgangsmåde til fremstilling deraf samt farmaceutiske præparater indeholdende disse forbindelser

Country Status (19)

Country Link
EP (1) EP0281242B1 (de)
JP (1) JP2585341B2 (de)
KR (1) KR960004859B1 (de)
CN (1) CN1017426B (de)
AT (1) ATE79373T1 (de)
AU (1) AU605235B2 (de)
CA (1) CA1299174C (de)
DE (1) DE3873562T2 (de)
DK (2) DK168434B1 (de)
ES (1) ES2042726T3 (de)
GR (1) GR3005737T3 (de)
HU (1) HU199789B (de)
IE (1) IE61511B1 (de)
IL (1) IL85189A (de)
NZ (1) NZ223293A (de)
PH (1) PH25095A (de)
PT (1) PT86619B (de)
SU (1) SU1553011A3 (de)
ZA (1) ZA88498B (de)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2439743A (en) * 1945-10-30 1948-04-13 Samuel M Mcewen Subsoiler and aerator

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GR1001395B (el) * 1987-03-23 1993-10-29 Michael Cohen Συν?έσεις και μέ?οδοι προς πραγματοποίηση αντισύλληψης.
AU644367B2 (en) * 1989-05-17 1993-12-09 Applied Medical Research Ltd Use of melatonin derivatives for effecting contraception
NZ233697A (en) * 1989-05-17 1996-12-20 Applied Med Res Ltd Contraceptive composition comprising a melatonin analogue and a progestogen and/or an estrogen
IT1243782B (it) * 1990-08-06 1994-06-28 Maria Francesca Devoto Composizione per il controllo della moltiplicazione di animali vertebrati per mezzo di mangimi od esche contenenti degli agonisti periferici di dopamina
FR2674522B1 (fr) * 1991-03-26 1993-07-16 Lipha Nouveaux derives de l'indole, procedes de preparation et medicaments les contenant.
US5196435A (en) * 1991-11-21 1993-03-23 Eli Lilly And Company Melatonin derivatives and combinations with antiestrogen compounds for treating mammalian breast carcinoma
US8445679B2 (en) 2007-04-16 2013-05-21 Abbvie Inc. 7-substituted indole MCL-1 inhibitors
US20150368220A1 (en) 2012-07-10 2015-12-24 Astellas Pharma Inc. Pharmaceutical composition for treating or preventing stress urinary incontinence or mixed urinary incontinence, and method for screening compound comprised in said pharmaceutical composition
CN104496882A (zh) * 2014-11-29 2015-04-08 湖北金赛药业有限公司 一种褪黑素的合成方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE43725B1 (en) * 1975-10-29 1981-05-06 Lilly Co Eli N-/2-(5-methoxy-6-halo-indol-3-yl)ethyl/-amides,methods for their preparation and their use
US4614807A (en) * 1984-10-04 1986-09-30 Eli Lilly And Company 6,7-dihalomelatonins

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2439743A (en) * 1945-10-30 1948-04-13 Samuel M Mcewen Subsoiler and aerator

Also Published As

Publication number Publication date
AU1097988A (en) 1988-08-04
ES2042726T3 (es) 1993-12-16
HUT46662A (en) 1988-11-28
EP0281242B1 (de) 1992-08-12
CA1299174C (en) 1992-04-21
PT86619B (pt) 1991-12-31
KR960004859B1 (ko) 1996-04-16
DK44688D0 (da) 1988-01-29
DE3873562D1 (de) 1992-09-17
CN1017426B (zh) 1992-07-15
HU199789B (en) 1990-03-28
IE880266L (en) 1988-08-02
SU1553011A3 (ru) 1990-03-23
ATE79373T1 (de) 1992-08-15
DK168434B1 (da) 1994-03-28
CN88100478A (zh) 1988-08-17
AU605235B2 (en) 1991-01-10
JP2585341B2 (ja) 1997-02-26
ZA88498B (en) 1989-10-25
KR880009926A (ko) 1988-10-05
EP0281242A1 (de) 1988-09-07
DE3873562T2 (de) 1993-03-04
IL85189A0 (en) 1988-07-31
JPS63196563A (ja) 1988-08-15
IE61511B1 (en) 1994-11-16
PH25095A (en) 1991-02-19
IL85189A (en) 1992-06-21
GR3005737T3 (de) 1993-06-07
NZ223293A (en) 1990-02-26
PT86619A (pt) 1988-02-01

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Legal Events

Date Code Title Description
B1 Patent granted (law 1993)
PUP Patent expired