DK4382A - Fremgangsmaade til fremstilling af stabile praeparater af levonantradol eller n-methyllevonantradol eller farmaceutisk acceptable syreadditionssalte deraf - Google Patents

Fremgangsmaade til fremstilling af stabile praeparater af levonantradol eller n-methyllevonantradol eller farmaceutisk acceptable syreadditionssalte deraf Download PDF

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Publication number
DK4382A
DK4382A DK4382A DK4382A DK4382A DK 4382 A DK4382 A DK 4382A DK 4382 A DK4382 A DK 4382A DK 4382 A DK4382 A DK 4382A DK 4382 A DK4382 A DK 4382A
Authority
DK
Denmark
Prior art keywords
methyllevonantradol
levonantradol
procedure
acid addition
addition salts
Prior art date
Application number
DK4382A
Other languages
Danish (da)
English (en)
Inventor
A J Aguiar
B Rasade
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of DK4382A publication Critical patent/DK4382A/da

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/107Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Dispersion Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Otolaryngology (AREA)
  • Hospice & Palliative Care (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK4382A 1981-01-09 1982-01-08 Fremgangsmaade til fremstilling af stabile praeparater af levonantradol eller n-methyllevonantradol eller farmaceutisk acceptable syreadditionssalte deraf DK4382A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/223,672 US4406888A (en) 1981-01-09 1981-01-09 Aqueous micellar solutions of levonantradol and N-methyllevonantradol and lyophilic forms thereof for reconstitution

Publications (1)

Publication Number Publication Date
DK4382A true DK4382A (da) 1982-07-10

Family

ID=22837540

Family Applications (1)

Application Number Title Priority Date Filing Date
DK4382A DK4382A (da) 1981-01-09 1982-01-08 Fremgangsmaade til fremstilling af stabile praeparater af levonantradol eller n-methyllevonantradol eller farmaceutisk acceptable syreadditionssalte deraf

Country Status (17)

Country Link
US (1) US4406888A (es)
EP (1) EP0056681A3 (es)
JP (1) JPS57136512A (es)
AU (1) AU528316B2 (es)
CA (1) CA1172569A (es)
CS (1) CS235524B2 (es)
DK (1) DK4382A (es)
ES (1) ES8304429A1 (es)
FI (1) FI813969L (es)
GR (1) GR76514B (es)
HU (1) HU186462B (es)
IL (1) IL64731A0 (es)
NO (1) NO820045L (es)
NZ (1) NZ199415A (es)
PH (1) PH17593A (es)
PT (1) PT74257B (es)
ZA (1) ZA82118B (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
USRE33239E (en) * 1983-09-06 1990-06-26 Farmaceutisk Laboratorium Ferring A/S Packaged stable enema solution or suspension containing 5-aminosalicyclic acid
US4657900A (en) * 1983-09-27 1987-04-14 Rowell Laboratories Pharmaceutical article of manufacture comprising a bisulfite stabilized aqueous solution of 5-aminosalicylic acid and method
GB9512854D0 (en) * 1995-06-23 1995-08-23 Wellcome Found Novel formulation
US8163797B2 (en) * 2003-12-31 2012-04-24 Actavis Elizabeth Llc Method of treating with stable pravastatin formulation

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2391552A (en) * 1942-02-25 1945-12-25 Curtis David Stabilized aromatic compounds
BE786427A (fr) * 1971-07-19 1973-01-18 Pfizer Compositions aqueuses de doxycycline
SE7704749L (sv) * 1976-05-17 1977-12-05 Pfizer Kinoliner och forfarande och mellanprodukter for framstellning derav
HU180916B (hu) 1976-05-17 1983-05-30 Pfizer Eljárás benzo[c]kinolin-származékok előállítására
US4260764A (en) * 1976-12-22 1981-04-07 Pfizer Inc. 9-Hydroxyoctahydrobenzo [C] quinolines and intermediates therefor
JPS54157818A (en) * 1978-06-02 1979-12-13 Tokyo Tanabe Co Injectionable preparation of chlorethylnitrosourea compound
US4320124A (en) * 1980-10-17 1982-03-16 Pfizer Inc. Composition for enhancing binding of a benzodiazepine to central benzodiazepine receptors and use thereof

Also Published As

Publication number Publication date
AU7940482A (en) 1982-07-22
HU186462B (en) 1985-08-28
CA1172569A (en) 1984-08-14
AU528316B2 (en) 1983-04-21
FI813969L (fi) 1982-07-10
GR76514B (es) 1984-08-10
NO820045L (no) 1982-07-12
ZA82118B (en) 1982-11-24
NZ199415A (en) 1985-04-30
PT74257A (en) 1982-02-01
IL64731A0 (en) 1982-03-31
US4406888A (en) 1983-09-27
JPS57136512A (en) 1982-08-23
PT74257B (en) 1984-05-29
PH17593A (en) 1984-10-02
ES508609A0 (es) 1983-03-01
ES8304429A1 (es) 1983-03-01
EP0056681A2 (en) 1982-07-28
CS235524B2 (en) 1985-05-15
EP0056681A3 (en) 1983-07-20

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AHB Application shelved due to non-payment