DK4281432T3 - Krystallisering af magnesium-l-laktat af høj renhed - Google Patents

Krystallisering af magnesium-l-laktat af høj renhed

Info

Publication number
DK4281432T3
DK4281432T3 DK22742375.3T DK22742375T DK4281432T3 DK 4281432 T3 DK4281432 T3 DK 4281432T3 DK 22742375 T DK22742375 T DK 22742375T DK 4281432 T3 DK4281432 T3 DK 4281432T3
Authority
DK
Denmark
Prior art keywords
lactate
crystallization
purity magnesium
purity
magnesium
Prior art date
Application number
DK22742375.3T
Other languages
Danish (da)
English (en)
Inventor
Tsvika Greener
Nitsan Papo
Assaf Harnoy
Original Assignee
Triplew Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Triplew Ltd filed Critical Triplew Ltd
Application granted granted Critical
Publication of DK4281432T3 publication Critical patent/DK4281432T3/da

Links

Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D9/00Crystallisation
    • B01D9/0018Evaporation of components of the mixture to be separated
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/02Preparation of carboxylic acids or their salts, halides or anhydrides from salts of carboxylic acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/42Separation; Purification; Stabilisation; Use of additives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/42Separation; Purification; Stabilisation; Use of additives
    • C07C51/43Separation; Purification; Stabilisation; Use of additives by change of the physical state, e.g. crystallisation
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/01Saturated compounds having only one carboxyl group and containing hydroxy or O-metal groups
    • C07C59/08Lactic acid
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M1/00Apparatus for enzymology or microbiology
    • C12M1/36Apparatus for enzymology or microbiology including condition or time responsive control, e.g. automatically controlled fermentors
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004Oxidoreductases (1.)
    • C12N9/0006Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P41/00Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/40Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/56Lactic acid
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07Optical isomers
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13Crystalline forms, e.g. polymorphs

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Sustainable Development (AREA)
  • Analytical Chemistry (AREA)
  • Molecular Biology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DK22742375.3T 2021-01-21 2022-01-19 Krystallisering af magnesium-l-laktat af høj renhed DK4281432T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202163139894P 2021-01-21 2021-01-21
US202163280150P 2021-11-17 2021-11-17
PCT/IL2022/050081 WO2022157768A1 (en) 2021-01-21 2022-01-19 Crystallization of high-purity magnesium l-lactate

Publications (1)

Publication Number Publication Date
DK4281432T3 true DK4281432T3 (da) 2026-04-20

Family

ID=82548988

Family Applications (1)

Application Number Title Priority Date Filing Date
DK22742375.3T DK4281432T3 (da) 2021-01-21 2022-01-19 Krystallisering af magnesium-l-laktat af høj renhed

Country Status (12)

Country Link
US (1) US20240300880A1 (https=)
EP (2) EP4736977A2 (https=)
JP (1) JP7720646B2 (https=)
KR (2) KR102896762B1 (https=)
CN (1) CN119330822A (https=)
AU (1) AU2022211203A1 (https=)
CA (1) CA3207836A1 (https=)
DK (1) DK4281432T3 (https=)
FI (1) FI4281432T3 (https=)
IL (1) IL303988B2 (https=)
MX (1) MX2023008459A (https=)
WO (1) WO2022157768A1 (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN116829529B (zh) * 2021-01-21 2024-10-18 三W有限公司 高纯度l-乳酸镁的结晶
CN119562940A (zh) * 2022-07-27 2025-03-04 三W有限公司 L-乳酸或其盐的对映体富集

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101018756B (zh) 2004-06-17 2011-06-08 普拉克生化公司 由含乳酸镁的介质制备乳酸或乳酸盐的方法
KR20110105845A (ko) * 2008-12-26 2011-09-27 도레이 카부시키가이샤 락트산 및 폴리락트산의 제조 방법
EP2399658A1 (en) * 2010-06-24 2011-12-28 Biosyn Arzneimittel GmbH Method for producing pharmacologically pure crystals
BR112013014646A2 (pt) 2010-12-13 2016-08-02 Toray Industries método para produção de um sal de ácido lático
EP2604696A1 (en) 2011-12-16 2013-06-19 PURAC Biochem BV Process for the fermentative production of lactic acid from a plant extract in the presence of a caustic magnesium salt
FR2994569B1 (fr) * 2012-08-17 2016-11-04 Roquette Freres Procede de fabrication de compositions riches en cristaux de mannitol sous forme delta, compositions et cristaux obtenus ainsi que leurs utilisations
WO2016016233A1 (en) 2014-07-28 2016-02-04 Purac Biochem Bv Method for the preparation of lactic acid
CN104789607B (zh) 2015-04-21 2018-01-12 北京化工大学 一种发酵‑分离耦合制备乳酸和/或乳酸盐的方法
CN105018538B (zh) 2015-07-07 2018-10-23 北京化工大学 一种基于结晶法发酵分离耦合生产乳酸镁的方法
US10920250B2 (en) 2016-04-12 2021-02-16 Purac Biochem Bv Magnesium lactate fermentation process
KR102218931B1 (ko) 2016-05-30 2021-02-24 푸락 바이오켐 비.브이. 고체 발효 생성물로부터 바이오매스를 분리하는 방법
CN106083565A (zh) * 2016-06-06 2016-11-09 宁乡新阳化工有限公司 乳酸镁的生产方法
WO2019068642A1 (en) 2017-10-02 2019-04-11 Metabolic Explorer PROCESS FOR PRODUCING ORGANIC ACID SALTS FROM A FERMENTATION BROTH
CN113166786B (zh) 2018-11-26 2025-01-24 三W有限公司 从具有高含量杂质的发酵液中纯化乳酸镁
EP4090443A1 (en) 2020-01-15 2022-11-23 Purac Biochem B.V. Method for purifying magnesium chloride solutions
MX2022010137A (es) 2020-02-19 2022-11-10 Triplew Ltd Metodos y sistemas para la produccion de acido lactico y el reciclaje del acido polilactico.
AU2022322001A1 (en) 2021-08-03 2024-02-29 TripleW Ltd. Process for producing recycled lactate salt

Also Published As

Publication number Publication date
AU2022211203A1 (en) 2023-08-10
JP2024504112A (ja) 2024-01-30
IL303988B1 (en) 2023-11-01
KR102896762B1 (ko) 2025-12-05
CN119330822A (zh) 2025-01-21
IL303988B2 (en) 2024-03-01
EP4736977A2 (en) 2026-05-06
MX2023008459A (es) 2023-07-27
EP4281432A1 (en) 2023-11-29
KR20230135613A (ko) 2023-09-25
IL303988A (en) 2023-08-01
EP4281432A4 (en) 2024-12-25
US20240300880A1 (en) 2024-09-12
KR20260003312A (ko) 2026-01-06
FI4281432T3 (fi) 2026-04-16
WO2022157768A1 (en) 2022-07-28
CA3207836A1 (en) 2022-07-28
EP4281432B1 (en) 2026-03-11
AU2022211203A9 (en) 2024-07-18
JP7720646B2 (ja) 2025-08-08

Similar Documents

Publication Publication Date Title
DK4281432T3 (da) Krystallisering af magnesium-l-laktat af høj renhed
DK3810581T3 (da) Krystalmodifikationer af odevixibat
IL286218A (en) Solid state forms of ripretinib
LT3472157T (lt) Kristalinės kietos bet inhibitoriaus formos
CY1126929T1 (el) Κρυσταλλικο υδροβρωμικο αλας της 5-μεο-dmt
DK3012255T3 (da) Stabil krystalform af tipiracilhydrochlorid og krystalliseringsfremgangsmåde dertil
DK2896405T3 (da) Fremstilling af gadobutrol med høj renhed
EP3478060A4 (en) ICE NUCLEATION FORMULATIONS FOR THE CRYCON PRESERVATION AND STABILIZATION OF BIOLOGICS
DK3328867T3 (da) Krystallinsk form af fri base af lorlatinib
EP4078999C0 (en) Audio rendering of audio sources
DK3294740T3 (da) Hidtil ukendte sulfonimidoylpurinonforbindelser og derivater til behandling og profylakse af virusinfektion
IL308051A (en) Lsd salt crystal forms
IL269792B (en) Crystalline forms of (s)-afoxolaner
DK3580197T3 (da) Oprensning af pleuromutilin
CU24476B1 (es) Nueva triterpenona c-3 con derivados de amida inversa c-17 como inhibidores de vih
DK3390422T3 (da) Krystalformer af lnt
DK3717503T3 (da) Albumin-bindende prodrugs af auristatin E derivater
IL282454A (en) Crystalline salts of a plasma kallikrein inhibitor
EP4308109A4 (en) SYNTHESIS OF ENDOQUINOL-LIKE QUINOLONES
DK3529236T3 (da) Krystalformer af eravacyclin
DK3823952T3 (da) Oprensning af levulinsyre
EP3808424A4 (en) CRYSTALLIZER AND CRYSTALLIZATION PROCESS
EP4305043A4 (en) Purification of sialooligosaccharides
DK3749673T3 (da) Krystallinsk form af bictegravir-natrium
EP2784174A4 (en) HIGH-CLEAN COPPER SPUTTER TARGET