DK426585A - Fremgangsmaade til udtrykkelse af et funktionelt polypeptid i bacillus og vektor til brug ved fremgangsmaaden - Google Patents

Fremgangsmaade til udtrykkelse af et funktionelt polypeptid i bacillus og vektor til brug ved fremgangsmaaden Download PDF

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Publication number
DK426585A
DK426585A DK426585A DK426585A DK426585A DK 426585 A DK426585 A DK 426585A DK 426585 A DK426585 A DK 426585A DK 426585 A DK426585 A DK 426585A DK 426585 A DK426585 A DK 426585A
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Prior art keywords
procedure
bacillus
expressing
vector
functional polypeptide
Prior art date
Application number
DK426585A
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English (en)
Other versions
DK426585D0 (da
Inventor
Steven Kovacevic
James Robert Miller
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of DK426585D0 publication Critical patent/DK426585D0/da
Publication of DK426585A publication Critical patent/DK426585A/da

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/62—Insulins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • C12N15/75—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Bacillus
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • C12N9/22—Ribonucleases RNAses, DNAses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/036—Fusion polypeptide containing a localisation/targetting motif targeting to the medium outside of the cell, e.g. type III secretion
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
    • C07K2319/74—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor
    • C07K2319/75—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor containing a fusion for activation of a cell surface receptor, e.g. thrombopoeitin, NPY and other peptide hormones

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DK426585A 1984-09-26 1985-09-20 Fremgangsmaade til udtrykkelse af et funktionelt polypeptid i bacillus og vektor til brug ved fremgangsmaaden DK426585A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US65443584A 1984-09-26 1984-09-26

Publications (2)

Publication Number Publication Date
DK426585D0 DK426585D0 (da) 1985-09-20
DK426585A true DK426585A (da) 1986-03-27

Family

ID=24624845

Family Applications (1)

Application Number Title Priority Date Filing Date
DK426585A DK426585A (da) 1984-09-26 1985-09-20 Fremgangsmaade til udtrykkelse af et funktionelt polypeptid i bacillus og vektor til brug ved fremgangsmaaden

Country Status (5)

Country Link
EP (1) EP0176320B1 (da)
JP (1) JPS6185190A (da)
DE (1) DE3578852D1 (da)
DK (1) DK426585A (da)
IL (1) IL76422A0 (da)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0154539A3 (en) * 1984-03-06 1986-12-30 Eli Lilly And Company Recombinant dna expression vectors and method for gene expression
US5011772A (en) * 1988-02-05 1991-04-30 Public Health Research Institute Of The City Of N.Y. High yield protein production system
GB9521568D0 (en) * 1995-10-20 1995-12-20 Lynxvale Ltd Delivery of biologically active polypeptides
WO1999050389A1 (en) * 1998-03-30 1999-10-07 Metabolix, Inc. Microbial strains and processes for the manufacture of biomaterials
US7780961B2 (en) 2001-05-03 2010-08-24 Actogenix N.V. Self-containing Lactococcus strain
JP2005529622A (ja) 2002-06-19 2005-10-06 ヴェーイーベー・ヴェーゼットウェー 腸吸収を促進するための方法および手段
DK2119450T3 (da) 2005-11-29 2013-05-06 Actogenix Nv Induktion af mucosal tolerance over for pankreatisk ø-beta-celle-autoantigener
ES2492468T3 (es) 2007-01-25 2014-09-09 Actogenix N.V. Tratamiento de enfermedad inmunitaria por administración a través de la mucosa de antígenos usando Lactobacillus genéticamente modificado
CN114752519B (zh) * 2022-02-25 2022-09-27 中国水产科学研究院南海水产研究所 一种利用发酵热带芽孢杆菌改善海水鱼发酵品质的方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5867181A (ja) * 1981-10-16 1983-04-21 Yakult Honsha Co Ltd スタフイロキナーゼ産生遺伝情報を担うｄｎａ断片組み換え体ｄｎａおよびそれを導入した大腸菌

Also Published As

Publication number Publication date
DK426585D0 (da) 1985-09-20
EP0176320A1 (en) 1986-04-02
JPS6185190A (ja) 1986-04-30
EP0176320B1 (en) 1990-07-25
IL76422A0 (en) 1986-01-31
DE3578852D1 (de) 1990-08-30

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