DK425487D0 - Pharmaceutisk aktive derivater af glutamin- og asparginsyre - Google Patents

Pharmaceutisk aktive derivater af glutamin- og asparginsyre

Info

Publication number
DK425487D0
DK425487D0 DK425487A DK425487A DK425487D0 DK 425487 D0 DK425487 D0 DK 425487D0 DK 425487 A DK425487 A DK 425487A DK 425487 A DK425487 A DK 425487A DK 425487 D0 DK425487 D0 DK 425487D0
Authority
DK
Denmark
Prior art keywords
glutaminic
pharmaceutical active
active derivatives
aspargic acid
aspargic
Prior art date
Application number
DK425487A
Other languages
English (en)
Other versions
DK169666B1 (da
DK425487A (da
Inventor
Francesco Makovec
Rolando Chiste
Claudio Lucio Rovati
Angelo Luigi Rovati
Original Assignee
Rotta Research Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rotta Research Lab filed Critical Rotta Research Lab
Publication of DK425487A publication Critical patent/DK425487A/da
Publication of DK425487D0 publication Critical patent/DK425487D0/da
Application granted granted Critical
Publication of DK169666B1 publication Critical patent/DK169666B1/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/30—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by doubly-bound oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/45—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK425487A 1985-12-17 1987-08-14 Farmaceutisk aktive derivater af D,L-glutamin- og D,L-asparaginsyre, fremgangsmåde til deres fremstilling samt farmaceutisk sammensætning og sammensætning til anvendelse ved husdyrbrug indeholdende sådanne derivater DK169666B1 (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
IT6806285 1985-12-17
IT8568062A IT1215169B (it) 1985-12-17 1985-12-17 Derivati alchil ossigenati degli acidi glutammico ed aspartico ad attivita antagonista su polipeptidi bioattivi e procedimento per la loro preparazione
EP8600724 1986-12-08
PCT/EP1986/000724 WO1987003869A2 (en) 1985-12-17 1986-12-08 Pharmaceutically active derivatives of glutamic and aspartic acids

Publications (3)

Publication Number Publication Date
DK425487A DK425487A (da) 1987-08-14
DK425487D0 true DK425487D0 (da) 1987-08-14
DK169666B1 DK169666B1 (da) 1995-01-09

Family

ID=11307569

Family Applications (1)

Application Number Title Priority Date Filing Date
DK425487A DK169666B1 (da) 1985-12-17 1987-08-14 Farmaceutisk aktive derivater af D,L-glutamin- og D,L-asparaginsyre, fremgangsmåde til deres fremstilling samt farmaceutisk sammensætning og sammensætning til anvendelse ved husdyrbrug indeholdende sådanne derivater

Country Status (13)

Country Link
US (1) US4769389A (da)
EP (1) EP0286643B1 (da)
JP (1) JPS62181246A (da)
AU (1) AU595858B2 (da)
CA (1) CA1269110A (da)
DK (1) DK169666B1 (da)
ES (1) ES2081777A6 (da)
GR (1) GR862921B (da)
IE (1) IE59534B1 (da)
IT (1) IT1215169B (da)
PT (1) PT83952B (da)
WO (1) WO1987003869A2 (da)
ZA (1) ZA869460B (da)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1196849B (it) * 1986-02-16 1988-11-25 Rotta Research Lab Nuovi derivati degli acidi 5 pentilammino 5 oxo pentaoico e 4 pentilammino 4 oxo butanoico ad attivita antagonista della colecistochinina e procedimento per la loro preparazione
US5089638A (en) * 1986-06-16 1992-02-18 Merck & Co., Inc. Amino acid analogs as CCK-antagonists
US4880938A (en) * 1986-06-16 1989-11-14 Merck & Co., Inc. Amino acid analogs
IT1217123B (it) * 1987-02-05 1990-03-14 Rotta Research Lab Derivati otticamente attivi dell acido 5 pentilammino 5 oxo pentanoico r ad attivita antagonista della colecistochinina e procedimento per la loro preparazione
US5105007A (en) * 1987-10-19 1992-04-14 Abbott Laboratories Phenylacetylglutamine (PAG) analytical test
EP0411668B2 (en) * 1989-08-04 1998-11-11 MERCK SHARP & DOHME LTD. Central cholecystokinin antagonists for treatment of psychiatric disorders
US5066828A (en) * 1990-04-12 1991-11-19 Merrell Dow Pharmaceuticals Inc. Difluoroglutamic acid conjugates with folates and anti-folates for the treatment of neoplastic diseases
JPH07507993A (ja) * 1991-12-20 1995-09-07 メルク　シヤープ　エンド　ドーム　リミテツド 医薬活性を有する中枢神経系コレシストキニンアンタゴニスト
GB9200420D0 (en) * 1992-01-09 1992-02-26 James Black Foundation The Lim Amino acid derivatives
US5716958A (en) 1994-10-27 1998-02-10 Tobishi Pharmaceutical Co., Ltd. Amino acid derivative having anti-CCK activity
JP5181118B2 (ja) * 2005-07-11 2013-04-10 ワイス・エルエルシー グルタミン酸アグリカナーゼ阻害剤
US7863330B2 (en) 2006-06-14 2011-01-04 Rottapharm S.P.A. Deloxiglumide and proton pump inhibitor combination in the treatment of gastrointestinal disorders
CN108912007B (zh) * 2018-06-20 2021-02-26 中国农业科学院兰州畜牧与兽药研究所 一种右氯谷胺的制备方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1108819A (en) * 1964-07-31 1968-04-03 Rotta Research Lab Derivatives of 2-acylaminobicarboxylic acids and method for preparing same
US3465081A (en) * 1966-05-13 1969-09-02 Thompson Chem Co Hayward Method of controlling pestiferous organisms
AT293368B (de) * 1969-10-13 1971-10-11 Rotta Research Lab Verfahren zur Herstellung von N-Benzoyl-L-(D- oder DL)-glutaminsäure-l-amiden
US3803223A (en) * 1970-07-20 1974-04-09 Searle & Co 3-amino-n-substituted succinamic acids and intermediates thereto
US4243678A (en) * 1977-12-30 1981-01-06 Byk Gulden Lomberg Chemische Fabrik Gmbh Acylhydrocarbylaminoalkanoic acids, compositions and uses
IE57892B1 (en) * 1984-06-25 1993-05-05 Rotta Research Lab Glutamic and aspartic acid derivatives
GB8704671D0 (en) * 1987-02-27 1987-04-01 Shell Int Research Glycine compounds

Also Published As

Publication number Publication date
IE863233L (en) 1987-06-17
DK169666B1 (da) 1995-01-09
AU6949787A (en) 1987-07-15
ZA869460B (en) 1987-08-26
JPS62181246A (ja) 1987-08-08
DK425487A (da) 1987-08-14
EP0286643A1 (en) 1988-10-19
PT83952A (en) 1987-01-01
US4769389A (en) 1988-09-06
ES2081777A6 (es) 1996-03-01
AU595858B2 (en) 1990-04-12
IE59534B1 (en) 1994-03-09
GR862921B (en) 1987-04-27
WO1987003869A3 (en) 1987-08-13
JPH0543698B2 (da) 1993-07-02
CA1269110A (en) 1990-05-15
PT83952B (pt) 1989-06-30
EP0286643B1 (en) 1991-05-15
IT1215169B (it) 1990-01-31
WO1987003869A2 (en) 1987-07-02
IT8568062A0 (it) 1985-12-17

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B1 Patent granted (law 1993)
PBP Patent lapsed

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