DK419877A - Fremgangsmaade til kemisk omdannelse af fortimicin-b til fortimicin-a og andre 4-n-acylfortimicin-b-derivater - Google Patents

Fremgangsmaade til kemisk omdannelse af fortimicin-b til fortimicin-a og andre 4-n-acylfortimicin-b-derivater

Info

Publication number
DK419877A
DK419877A DK419877A DK419877A DK419877A DK 419877 A DK419877 A DK 419877A DK 419877 A DK419877 A DK 419877A DK 419877 A DK419877 A DK 419877A DK 419877 A DK419877 A DK 419877A
Authority
DK
Denmark
Prior art keywords
fortimicin
acylfortimicin
derivatives
procedure
chemical conversion
Prior art date
Application number
DK419877A
Other languages
Danish (da)
English (en)
Inventor
J S Tadanier
J R Martin
P Kurath
Original Assignee
Kyowa Hakko Kogyo Kk
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kyowa Hakko Kogyo Kk filed Critical Kyowa Hakko Kogyo Kk
Publication of DK419877A publication Critical patent/DK419877A/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/22—Cyclohexane rings, substituted by nitrogen atoms
    • C07H15/222—Cyclohexane rings substituted by at least two nitrogen atoms
    • C07H15/224—Cyclohexane rings substituted by at least two nitrogen atoms with only one saccharide radical directly attached to the cyclohexyl radical, e.g. destomycin, fortimicin, neamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
DK419877A 1976-09-23 1977-09-22 Fremgangsmaade til kemisk omdannelse af fortimicin-b til fortimicin-a og andre 4-n-acylfortimicin-b-derivater DK419877A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/725,829 US4091032A (en) 1976-09-23 1976-09-23 4-N-acylfortimicin B derivatives and the chemical conversion of fortimicin B to fortimicin A

Publications (1)

Publication Number Publication Date
DK419877A true DK419877A (da) 1978-03-24

Family

ID=24916124

Family Applications (1)

Application Number Title Priority Date Filing Date
DK419877A DK419877A (da) 1976-09-23 1977-09-22 Fremgangsmaade til kemisk omdannelse af fortimicin-b til fortimicin-a og andre 4-n-acylfortimicin-b-derivater

Country Status (17)

Country Link
US (2) US4091032A (fr)
JP (1) JPS5368752A (fr)
AR (1) AR224722A1 (fr)
AU (1) AU519064B2 (fr)
BE (1) BE859012A (fr)
CA (1) CA1114809A (fr)
DE (1) DE2742949C2 (fr)
DK (1) DK419877A (fr)
ES (2) ES462566A1 (fr)
FR (1) FR2365586A1 (fr)
GB (2) GB1591320A (fr)
GR (1) GR63596B (fr)
NO (1) NO773256L (fr)
NZ (1) NZ185239A (fr)
PH (1) PH16052A (fr)
SE (1) SE7710683L (fr)
ZA (2) ZA775651B (fr)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GR66054B (fr) * 1976-10-28 1981-01-14 Abbott Lab
JPS5466679A (en) * 1977-11-07 1979-05-29 Kyowa Hakko Kogyo Co Ltd Novel antibiotic substance fortimicin kf and fortimicin kg, and their preparation
US4214075A (en) * 1977-12-21 1980-07-22 Abbott Laboratories 6'-Epi-fortimicin A and B derivatives
JPS6041679B2 (ja) * 1978-03-03 1985-09-18 協和醗酵工業株式会社 新抗生物質ホ−テイマイシンｋｇ↓１，ｋｇ↓２およびｋｇ↓３ならびにそれらの製造法
US4234717A (en) * 1978-03-30 1980-11-18 American Cyanamid Company Antibacterial antibiotic BM782
US4208407A (en) * 1979-02-05 1980-06-17 Abbott Laboratories 5-Deoxyfortimicin A, 2,5-dideoxyfortimicin A and the corresponding 4-N-acyl and alkyl fortimicin B derivatives thereof and intermediates therefor
US4207415A (en) * 1979-02-05 1980-06-10 Abbott Laboratories Method of producing 2-deoxyfortimicin A
US4219644A (en) * 1979-03-29 1980-08-26 Abbott Laboratories Fortimicins AH and AI
US4213971A (en) * 1979-03-29 1980-07-22 Abbott Laboratories 4-N, 2'-N and 4,2'-Di-N-fortimicin AD derivatives
US4218442A (en) * 1979-03-29 1980-08-19 Abbott Laboratories 1-Epi-fortimicin A and derivatives
JPS55130969A (en) * 1979-03-29 1980-10-11 Abbott Lab 11epiifortimicin a and derivative
US4219643A (en) * 1979-03-29 1980-08-26 Abbott Laboratories Fortimicin AN
US4331804A (en) * 1979-03-29 1982-05-25 Abbott Laboratories 2-Epi-fortimicin A and derivatives
US4214078A (en) * 1979-03-29 1980-07-22 Abbott Laboratories Fortimicin AL
US4214080A (en) * 1979-03-29 1980-07-22 Abbott Laboratories Fortimicins AM and AP
US4213972A (en) * 1979-03-29 1980-07-22 Abbott Laboratories 4-N, 2'-N and 4,2'Di-N-fortimicins AH and AI
US4293689A (en) * 1979-03-29 1981-10-06 Abbott Laboratories Method of producing 3-O-demethylfortimicin B from fortimicin AN
US4214079A (en) * 1979-03-29 1980-07-22 Abbott Laboratories 4-N, 2'-N and 4,2'-Di-N-fortimicin AL derivatives
US4213974A (en) * 1979-03-29 1980-07-22 Abbott Laboratories 4-N,2'-N and 4,2'-Di-N-fortimicin AO derivatives
US4216210A (en) * 1979-03-29 1980-08-05 Abbott Laboratories Fortimicins AM and AP derivatives
US4226979A (en) * 1979-03-29 1980-10-07 Abbott Laboratories Fortimicin AK
US4219642A (en) * 1979-03-29 1980-08-26 Abbott Laboratories Fortimicin AO
US4275193A (en) * 1979-09-26 1981-06-23 Abbott Laboratories 4,5-Carbamates of fortimicin B
US4263429A (en) * 1979-09-26 1981-04-21 Abbott Laboratories 1,2,6-Tri-N-benzyloxycarbonylfortimicin B-4,5-carbamate and 1,2,6-tri-N-acetylfortimicin B-4,5-carbamate
US4273925A (en) * 1979-09-26 1981-06-16 Abbott Laboratories 1,2-Modified fortimicins A and B, intermediates therefor and method for their manufacture
US4340727A (en) * 1979-09-26 1982-07-20 Abbott Laboratories 1,2-Modified fortimicins A and B, intermediates therefor and method for their manufacture
US4431799A (en) * 1979-09-26 1984-02-14 Abbott Laboratories 6'-Modified fortimicin compounds
US4232147A (en) * 1979-09-26 1980-11-04 Abbott Laboratories 4-N-Acylfortimicin B-1,5-carbamates
US4252972A (en) * 1979-09-26 1981-02-24 Abbott Laboratories Fortimicin B-1,2:4,5-bis-carbamates
US4230846A (en) * 1979-09-26 1980-10-28 Abbott Laboratories 1,5-Carbamates of fortimicin B and derivatives
US4269970A (en) * 1979-09-26 1981-05-26 Abbott Laboratories 1,2-Carbamates of fortimicin B and derivatives
US4382926A (en) * 1980-04-01 1983-05-10 Zaidan Hojin Biseibutsu Kagaku Kenkyu Kai Formimidoyl A and B useful as semi-synthetic aminoglycosidic antibiotics
US4338309A (en) * 1980-11-10 1982-07-06 Abbott Laboratories 4',5'-Dihydro-antibiotic AX-127B-1; 2'-N-des-β-lysyl-4',5'-dihydro-antibiotic AX-127B-1; and 4-N-derivatives thereof
US4338307A (en) * 1980-11-10 1982-07-06 Abbott Laboratories 2'-N-Des-β-lysyl antibiotic AX-127B-1 and 4-N-acyl and alkyl derivatives thereof
US4338308A (en) * 1980-11-10 1982-07-06 Abbott Laboratories 4-N-β-Lysyl-2'-N-des-β-lysyl antibiotic AX-127B-1 and the pharmaceutically acceptable salts thereof
IE54288B1 (en) * 1982-03-05 1989-08-16 Fujisawa Pharmaceutical Co New 1,4-diaminocyclitol derivatives, processes for their preparation and pharmaceutical compositions containing them

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3931400A (en) * 1973-04-17 1976-01-06 Abbott Laboratories Fortimicin B and process for production thereof
JPS5145675B2 (fr) * 1973-07-23 1976-12-04
JPS5246311B2 (fr) * 1973-04-17 1977-11-24
JPS50145588A (fr) * 1974-05-16 1975-11-21

Also Published As

Publication number Publication date
JPS5368752A (en) 1978-06-19
FR2365586B1 (fr) 1982-12-17
FR2365586A1 (fr) 1978-04-21
NO773256L (no) 1978-03-29
US4155902A (en) 1979-05-22
SE7710683L (sv) 1978-03-24
ZA775651B (en) 1979-07-25
GB1591320A (en) 1981-06-17
GR63596B (en) 1979-11-26
ES472608A1 (es) 1979-02-16
NZ185239A (en) 1980-08-26
DE2742949C2 (de) 1983-08-04
BE859012A (fr) 1978-03-23
PH16052A (en) 1983-06-02
AR224722A1 (es) 1982-01-15
CA1114809A (fr) 1981-12-22
ZA775652B (en) 1979-04-25
AU519064B2 (en) 1981-11-05
US4091032A (en) 1978-05-23
GB1591606A (en) 1981-06-24
DE2742949A1 (de) 1978-03-30
ES462566A1 (es) 1978-11-16
AU2902577A (en) 1979-03-29

Similar Documents

Publication Publication Date Title
DK419877A (da) Fremgangsmaade til kemisk omdannelse af fortimicin-b til fortimicin-a og andre 4-n-acylfortimicin-b-derivater
DK575976A (da) Fremgangsmade til kemisk modifikation af polyolefiner for at forbedre disses befugtelighed
DK59677A (da) Fremgangsmade til fremstilling af prolinderivater og dermed beslegtede forbindelser
NO153049C (no) Fremgangsmaate og reaktor for ammoniakk-syntese.
DK102177A (da) Aminoalkyl-heterocycliske forbindelser og fremgangsmade til fremstilling deraf
DK267978A (da) I laengderetningen opdelt soejlestruktur og fremgangsmaade til fremstilling af samme
SE428019B (sv) Forfarande for omvandling av cis-hexahydro-dibenso (b,d) pyran-9-oner till trans-hexahydro-dibenso (b,d) pyran-9-oner
DK73577A (da) Forbindelsesanordning til indbyrdes forbindelse af i det mindste to legemer
DK180878A (da) Fremgangsmaade til fremstilling af imidazoaziner og imidazodiaziner
DK496977A (da) Fremgangsmaade til fremstilling af 0-alkylerede hydroxylaminer og syreadditionssalte deraf
DK290278A (da) Fremgangsmaade til fremstilling af amilorid og andre 6-substituerede derivater deraf
DK517579A (da) Fremgangsmaade til renfremstilling af kaliumribonat og ribonolacton
DK205876A (da) Kobling til overforing af synkront og asynkront optredende data
DK66577A (da) Terner azeotrop af fluorkiselsyre, hydrogenfluorid og vand
DK565878A (da) Fremgangsmaade til fremstilling af vandgelsspraengstoffer
DK2279A (da) Fremgangsmaade til fremstilling af heterocyclisk substituerede og eventuelt hydroxysubstituerede (3-alkylamino-2-hydroxy-propoxy) pyridiner
DK266878A (da) Anlaeg til central frembringelse af termisk nytteenergi
DK418177A (da) Er bjaelke og fremgangsmaade til fremsitlling af saadanne bjaelk
DK419977A (da) 4-(-substituerede derivater af fortimicin b og fremgangsmaade til kemisk omdannelse af fortimicin b til fortimicin c og andre 4-substituerede fortimicin-b- derivater
DK235477A (da) Fremgangsmade til fremstilling af uracilderivater
DK228676A (da) Stabile oplosninger af ergotpeptidalkaloider og fremgangsmade til fremstilling deraf
DK117177A (da) Fremgangsmade og reaktor til fremstilling af kobberphthalocyanin
DK11477A (da) Fremgangsmade og anleg til dehydrering af ramaterialer
DK561776A (da) Thiadiazolylderivater af 7-acylamido-3-cephem-4-carboxylsyre og fremgangsmade til fremstilling deraf
DK549577A (da) Fremgangsmaade til fremsitlling af oelurt

Legal Events

Date Code Title Description
AHB Application shelved due to non-payment