DK4155409T3 - Fremgangsmåde til at øge replikationen af et cirkulært dna-molekyle - Google Patents
Fremgangsmåde til at øge replikationen af et cirkulært dna-molekyle Download PDFInfo
- Publication number
- DK4155409T3 DK4155409T3 DK22195354.0T DK22195354T DK4155409T3 DK 4155409 T3 DK4155409 T3 DK 4155409T3 DK 22195354 T DK22195354 T DK 22195354T DK 4155409 T3 DK4155409 T3 DK 4155409T3
- Authority
- DK
- Denmark
- Prior art keywords
- replication
- increasing
- dna molecule
- circular dna
- circular
- Prior art date
Links
- 108020004638 Circular DNA Proteins 0.000 title 1
- 102000053602 DNA Human genes 0.000 title 1
- 230000010076 replication Effects 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/67—General methods for enhancing the expression
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/65—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression using markers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/70—Vectors or expression systems specially adapted for E. coli
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2800/00—Nucleic acids vectors
- C12N2800/10—Plasmid DNA
- C12N2800/101—Plasmid DNA for bacteria
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2800/00—Nucleic acids vectors
- C12N2800/20—Pseudochromosomes, minichrosomosomes
- C12N2800/202—Pseudochromosomes, minichrosomosomes of bacteriophage origin
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2800/00—Nucleic acids vectors
- C12N2800/20—Pseudochromosomes, minichrosomosomes
- C12N2800/204—Pseudochromosomes, minichrosomosomes of bacterial origin, e.g. BAC
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2820/00—Vectors comprising a special origin of replication system
- C12N2820/55—Vectors comprising a special origin of replication system from bacteria
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2820/00—Vectors comprising a special origin of replication system
- C12N2820/60—Vectors comprising a special origin of replication system from viruses
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2830/00—Vector systems having a special element relevant for transcription
- C12N2830/50—Vector systems having a special element relevant for transcription regulating RNA stability, not being an intron, e.g. poly A signal
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
- C12R2001/00—Microorganisms ; Processes using microorganisms
- C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
- C12R2001/185—Escherichia
- C12R2001/19—Escherichia coli
Landscapes
- Genetics & Genomics (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Wood Science & Technology (AREA)
- Organic Chemistry (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP2015068398 | 2015-08-10 | ||
EP20201524.4A EP3825407A1 (en) | 2015-08-10 | 2016-08-04 | Method of increasing the replication of a circular dna molecule |
Publications (2)
Publication Number | Publication Date |
---|---|
DK4155409T3 true DK4155409T3 (da) | 2024-02-26 |
DK4155409T5 DK4155409T5 (da) | 2024-07-22 |
Family
ID=53887104
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK16750759.9T DK3334828T3 (en) | 2015-08-10 | 2016-08-04 | Fremgangsmåde til at øge replikationen af et cirkulært dna-molekyle |
DK22195354.0T DK4155409T5 (da) | 2015-08-10 | 2016-08-04 | Fremgangsmåde til at øge replikationen af et cirkulært dna-molekyle |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK16750759.9T DK3334828T3 (en) | 2015-08-10 | 2016-08-04 | Fremgangsmåde til at øge replikationen af et cirkulært dna-molekyle |
Country Status (9)
Country | Link |
---|---|
US (2) | US20230167456A2 (da) |
EP (3) | EP3825407A1 (da) |
CN (2) | CN108138187B (da) |
DE (1) | DE22195354T1 (da) |
DK (2) | DK3334828T3 (da) |
ES (2) | ES2974612T3 (da) |
PL (1) | PL4155409T3 (da) |
PT (2) | PT3334828T (da) |
WO (1) | WO2017025447A1 (da) |
Families Citing this family (54)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2012019630A1 (en) | 2010-08-13 | 2012-02-16 | Curevac Gmbh | Nucleic acid comprising or coding for a histone stem-loop and a poly(a) sequence or a polyadenylation signal for increasing the expression of an encoded protein |
WO2012116714A1 (en) | 2011-03-02 | 2012-09-07 | Curevac Gmbh | Vaccination in elderly patients |
WO2013120497A1 (en) | 2012-02-15 | 2013-08-22 | Curevac Gmbh | Nucleic acid comprising or coding for a histone stem-loop and a poly(a) sequence or a polyadenylation signal for increasing the expression of an encoded therapeutic protein |
SG10201710473VA (en) | 2013-02-22 | 2018-02-27 | Curevac Ag | Combination of vaccination and inhibition of the pd-1 pathway |
KR20160044566A (ko) | 2013-08-21 | 2016-04-25 | 큐어백 아게 | 호흡기 세포융합 바이러스 |
BR112016001192A2 (pt) | 2013-08-21 | 2017-08-29 | Curevac Ag | Vacina contra a raiva |
EP3230458B1 (en) | 2014-12-12 | 2020-02-19 | CureVac AG | Artificial nucleic acid molecules for improved protein expression |
US10653768B2 (en) | 2015-04-13 | 2020-05-19 | Curevac Real Estate Gmbh | Method for producing RNA compositions |
WO2016165831A1 (en) | 2015-04-17 | 2016-10-20 | Curevac Ag | Lyophilization of rna |
EP3289101B1 (en) | 2015-04-30 | 2021-06-23 | CureVac AG | Immobilized poly(n)polymerase |
DK3294885T3 (da) | 2015-05-08 | 2020-08-10 | Curevac Real Estate Gmbh | Fremgangsmåde til at fremstille rna |
SG11201708652YA (en) | 2015-05-15 | 2017-11-29 | Curevac Ag | Prime-boost regimens involving administration of at least one mrna construct |
EP3916091A3 (en) | 2015-05-20 | 2022-03-30 | CureVac AG | Dry powder composition comprising long-chain rna |
SG11201708541QA (en) | 2015-05-20 | 2017-12-28 | Curevac Ag | Dry powder composition comprising long-chain rna |
PT3303583T (pt) | 2015-05-29 | 2020-07-07 | Curevac Ag | Um método para produção e purificação de rna, compreendendendo pelo menos um passo de filtração por fluxo tangencial |
US11608513B2 (en) | 2015-05-29 | 2023-03-21 | CureVac SE | Method for adding cap structures to RNA using immobilized enzymes |
US10501768B2 (en) | 2015-07-13 | 2019-12-10 | Curevac Ag | Method of producing RNA from circular DNA and corresponding template DNA |
PL4155409T3 (pl) | 2015-08-10 | 2024-06-17 | CureVac Manufacturing GmbH | Sposób zwiększania replikacji kolistej cząsteczki dna |
WO2017064146A1 (en) | 2015-10-12 | 2017-04-20 | Curevac Ag | Automated method for isolation, selection and/or detection of microorganisms or cells comprised in a solution |
WO2017081110A1 (en) | 2015-11-09 | 2017-05-18 | Curevac Ag | Rotavirus vaccines |
AU2016375021B2 (en) | 2015-12-22 | 2022-02-03 | CureVac SE | Method for producing RNA molecule compositions |
WO2017109161A1 (en) | 2015-12-23 | 2017-06-29 | Curevac Ag | Method of rna in vitro transcription using a buffer containing a dicarboxylic acid or tricarboxylic acid or a salt thereof |
WO2017140905A1 (en) | 2016-02-17 | 2017-08-24 | Curevac Ag | Zika virus vaccine |
EP3423595A1 (en) | 2016-03-03 | 2019-01-09 | CureVac AG | Rna analysis by total hydrolysis |
EP3448427A1 (en) | 2016-04-29 | 2019-03-06 | CureVac AG | Rna encoding an antibody |
WO2017191264A1 (en) | 2016-05-04 | 2017-11-09 | Curevac Ag | Nucleic acid molecules and uses thereof |
WO2017191274A2 (en) | 2016-05-04 | 2017-11-09 | Curevac Ag | Rna encoding a therapeutic protein |
AU2017277731B2 (en) | 2016-06-09 | 2021-02-18 | CureVac SE | Hybrid carriers for nucleic acid cargo |
WO2018096179A1 (en) | 2016-11-28 | 2018-05-31 | Curevac Ag | Method for purifying rna |
EP3808380A1 (en) | 2016-12-08 | 2021-04-21 | CureVac AG | Rna for treatment or prophylaxis of a liver disease |
WO2018104540A1 (en) | 2016-12-08 | 2018-06-14 | Curevac Ag | Rnas for wound healing |
WO2018115507A2 (en) | 2016-12-23 | 2018-06-28 | Curevac Ag | Henipavirus vaccine |
EP3558354A1 (en) | 2016-12-23 | 2019-10-30 | CureVac AG | Lassa virus vaccine |
US11141476B2 (en) | 2016-12-23 | 2021-10-12 | Curevac Ag | MERS coronavirus vaccine |
BR112019015244A2 (pt) | 2017-03-24 | 2020-04-14 | Curevac Ag | ácidos nucleicos codificando proteínas associadas a crispr e usos dos mesmos |
US11357856B2 (en) | 2017-04-13 | 2022-06-14 | Acuitas Therapeutics, Inc. | Lipids for delivery of active agents |
RU2020103379A (ru) | 2017-07-04 | 2021-08-04 | Куревак Аг | Новые молекулы нуклеиновых кислот |
US11602557B2 (en) | 2017-08-22 | 2023-03-14 | Cure Vac SE | Bunyavirales vaccine |
CN107875375A (zh) * | 2017-10-10 | 2018-04-06 | 郑州大学 | rMBP‑NAP调控巨噬细胞及直接抗肿瘤的用途 |
US11692002B2 (en) | 2017-11-08 | 2023-07-04 | CureVac SE | RNA sequence adaptation |
WO2019115635A1 (en) | 2017-12-13 | 2019-06-20 | Curevac Ag | Flavivirus vaccine |
US11525158B2 (en) | 2017-12-21 | 2022-12-13 | CureVac SE | Linear double stranded DNA coupled to a single support or a tag and methods for producing said linear double stranded DNA |
BR112020020933A2 (pt) | 2018-04-17 | 2021-04-06 | Curevac Ag | Moléculas de rna de rsv inovadoras e composições para vacinação |
CN108611310A (zh) * | 2018-04-28 | 2018-10-02 | 中国药科大学 | 一种重组Hsp65与STEAP1186-193融合蛋白的基因工程菌的构建 |
US20220042038A1 (en) * | 2018-12-20 | 2022-02-10 | Poseida Therapeutics, Inc. | Nanotransposon compositions and methods of use |
RU2730661C2 (ru) * | 2018-12-27 | 2020-08-24 | Селл энд Джин Терапи Лтд | Генотерапевтический ДНК-вектор на основе генотерапевтического ДНК-вектора VTvaf17, несущий целевой ген, выбранный из группы генов COL1A1, COL1A2, P4HA1, P4HA2, COL7A1, CLCA2, ELN, PLOD1 для повышения уровня экспрессии этих целевых генов, способ его получения и применения, штамм Escherichia coli SCS110-AF/VTvaf17-COL1A1, или Escherichia coli SCS110-AF/VTvaf17-COL1A2, или Escherichia coli SCS110-AF/VTvaf17-P4HA1, или Escherichia coli SCS110-AF/VTvaf17-P4HA2, или Escherichia coli SCS110-AF/VTvaf17-COL7A1, или Escherichia coli SCS110-AF/VTvaf17-CLCA2, или Escherichia coli SCS110-AF/VTvaf17-ELN, или Escherichia coli SCS110-AF/VTvaf17- PLOD1, несущий генотерапевтический ДНК-вектор, способ его получения, способ производства в промышленных масштабах генотерапевтического ДНК-вектора |
WO2020201022A1 (en) * | 2019-03-29 | 2020-10-08 | Danmarks Tekniske Universitet | Automation-ready dna cloning by bacterial natural transformation |
CN113122622A (zh) * | 2019-12-31 | 2021-07-16 | 南京优智源医药科技有限公司 | 一种通过piR-31925对弱精症诊断试剂盒及应用 |
US11241493B2 (en) | 2020-02-04 | 2022-02-08 | Curevac Ag | Coronavirus vaccine |
US20240277830A1 (en) | 2020-02-04 | 2024-08-22 | CureVac SE | Coronavirus vaccine |
CA3174215A1 (en) | 2020-04-22 | 2021-10-28 | Ugur Sahin | Coronavirus vaccine |
KR20230164648A (ko) | 2020-12-22 | 2023-12-04 | 큐어백 에스이 | SARS-CoV-2 변이체에 대한 RNA 백신 |
US20240102065A1 (en) | 2021-01-27 | 2024-03-28 | CureVac SE | Method of reducing the immunostimulatory properties of in vitro transcribed rna |
US11878055B1 (en) | 2022-06-26 | 2024-01-23 | BioNTech SE | Coronavirus vaccine |
Family Cites Families (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0180192B1 (en) * | 1984-10-29 | 1992-02-05 | Research Association For Utilization Of Light Oil | Novel plasmids |
KR20070053765A (ko) | 2004-08-19 | 2007-05-25 | 네이쳐 테크놀로지 코포레이션 | 플라스미드 디엔에이 발효 공정 |
DE102005046490A1 (de) * | 2005-09-28 | 2007-03-29 | Johannes-Gutenberg-Universität Mainz | Modifikationen von RNA, die zu einer erhöhten Transkriptstabilität und Translationseffizienz führen |
US9045759B2 (en) | 2009-01-21 | 2015-06-02 | James Arthur Williams | DNA plasmids with improved copy number |
WO2012019630A1 (en) | 2010-08-13 | 2012-02-16 | Curevac Gmbh | Nucleic acid comprising or coding for a histone stem-loop and a poly(a) sequence or a polyadenylation signal for increasing the expression of an encoded protein |
EP3492109B1 (en) | 2011-10-03 | 2020-03-04 | ModernaTX, Inc. | Modified nucleosides, nucleotides, and nucleic acids, and uses thereof |
BR112014023800A2 (pt) * | 2012-03-27 | 2017-07-18 | Curevac Gmbh | moléculas de ácidos nucleicos artificiais |
WO2014035457A1 (en) * | 2012-08-29 | 2014-03-06 | Nature Technology Corporation | Dna plasmids with improved expression |
US9365641B2 (en) | 2012-10-01 | 2016-06-14 | The Trustees Of The University Of Pennsylvania | Compositions and methods for targeting stromal cells for the treatment of cancer |
WO2014152027A1 (en) * | 2013-03-15 | 2014-09-25 | Moderna Therapeutics, Inc. | Manufacturing methods for production of rna transcripts |
CN104278055B (zh) * | 2013-07-04 | 2019-01-25 | 中国科学院上海巴斯德研究所 | 制备hbv持续感染动物模型的试剂和方法 |
CA2915724C (en) * | 2013-08-21 | 2023-09-26 | Patrick Baumhof | Method for increasing expression of rna-encoded proteins |
NO3068888T3 (da) * | 2013-11-12 | 2018-06-30 | ||
US20150167017A1 (en) | 2013-12-13 | 2015-06-18 | Moderna Therapeutics, Inc. | Alternative nucleic acid molecules and uses thereof |
BR102014014502B1 (pt) * | 2014-06-13 | 2020-09-15 | Ouro Fino Saúde Animal Ltda | Vetor de expressão |
PL4155409T3 (pl) | 2015-08-10 | 2024-06-17 | CureVac Manufacturing GmbH | Sposób zwiększania replikacji kolistej cząsteczki dna |
-
2016
- 2016-08-04 PL PL22195354.0T patent/PL4155409T3/pl unknown
- 2016-08-04 CN CN201680047477.2A patent/CN108138187B/zh active Active
- 2016-08-04 EP EP20201524.4A patent/EP3825407A1/en active Pending
- 2016-08-04 PT PT167507599T patent/PT3334828T/pt unknown
- 2016-08-04 US US15/750,745 patent/US20230167456A2/en active Pending
- 2016-08-04 DE DE22195354.0T patent/DE22195354T1/de active Pending
- 2016-08-04 CN CN202210790009.1A patent/CN116064623A/zh active Pending
- 2016-08-04 WO PCT/EP2016/068702 patent/WO2017025447A1/en active Application Filing
- 2016-08-04 DK DK16750759.9T patent/DK3334828T3/da active
- 2016-08-04 EP EP22195354.0A patent/EP4155409B1/en active Active
- 2016-08-04 ES ES22195354T patent/ES2974612T3/es active Active
- 2016-08-04 DK DK22195354.0T patent/DK4155409T5/da active
- 2016-08-04 PT PT221953540T patent/PT4155409T/pt unknown
- 2016-08-04 EP EP16750759.9A patent/EP3334828B1/en active Active
- 2016-08-04 ES ES16750759T patent/ES2837100T3/es active Active
-
2022
- 2022-09-14 US US17/932,026 patent/US20230027681A1/en active Pending
Also Published As
Publication number | Publication date |
---|---|
EP3334828B1 (en) | 2020-10-28 |
EP3334828A1 (en) | 2018-06-20 |
EP3825407A1 (en) | 2021-05-26 |
CN108138187B (zh) | 2022-07-19 |
US20190225971A1 (en) | 2019-07-25 |
DK4155409T5 (da) | 2024-07-22 |
PT3334828T (pt) | 2020-12-18 |
PL4155409T3 (pl) | 2024-06-17 |
EP4155409A1 (en) | 2023-03-29 |
US20230027681A1 (en) | 2023-01-26 |
WO2017025447A1 (en) | 2017-02-16 |
DE22195354T1 (de) | 2023-05-25 |
DK3334828T3 (en) | 2020-12-14 |
PT4155409T (pt) | 2024-02-26 |
US20230167456A2 (en) | 2023-06-01 |
CN108138187A (zh) | 2018-06-08 |
CN116064623A (zh) | 2023-05-05 |
ES2974612T3 (es) | 2024-06-28 |
EP4155409B1 (en) | 2023-12-27 |
ES2837100T3 (es) | 2021-06-29 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DK4155409T5 (da) | Fremgangsmåde til at øge replikationen af et cirkulært dna-molekyle | |
DK3445850T3 (da) | Fremgangsmåder til tilvejebringelse af enkeltstrenget rna | |
DK3497207T3 (da) | Fremgangsmåder til påvisning af aav | |
DK3294700T3 (da) | Fremgangsmåde til fremstilling af limonen-4-ol | |
DK3198035T3 (da) | Fremgangsmåder til forudsigelse af medicinrespons | |
DK3122444T3 (da) | Fremgangsmåde til fremstilling af membraner | |
DK3274469T3 (da) | Fremgangsmåder til detektering af en biologisk kontaminant | |
DK3359281T3 (da) | Fremgangsmåde til udtrækning af CO2 | |
DK3204398T3 (da) | Fremgangsmåder til fraseparering af gemcitabin-phosphat diastereoisomerer | |
DK3314010T3 (da) | Fremgangsmåde til detektering af kromosomaberrationer | |
DK3377201T3 (da) | Fremgangsmåde til fremstilling af membraner | |
DK3519094T3 (da) | System til forberedelse af en prøve | |
DK3393468T3 (da) | Fremgangsmåder til behandling af en immundefektsygdom | |
DK3303613T3 (da) | Fremgangsmåde til detektering af aktivitet af en polymerase | |
DK3102702T3 (da) | Fejlfri sekvensering af DNA | |
DK3206586T3 (da) | Fremgangsmåde til detektion af dikrotisk hak | |
DK3529262T3 (da) | Fremgangsmåder til fremme af t-cellerespons | |
DK3164716T3 (da) | Fremgangsmåde til diagnosticering af neurodegenerative sygdomme | |
DK3408015T3 (da) | Fremgangsmåde til fremstilling af emulsioner | |
DK3367910T3 (da) | Fremgangsmåde til anvendelse af en sondeafdækning | |
DK3177931T3 (da) | Fremgangsmåde til bestemmelse af stoffers evne til at binde til analytaktive steder | |
DK3328574T3 (da) | Fremgangsmåde til fremstilling af en monotektisk legering | |
DK3274143T3 (da) | Fremgangsmåde til fremstilling af lignocellulosematerialer | |
DK3302788T3 (da) | Fremgangsmåde til fremstilling af en sorbent | |
DK3430072T3 (da) | Fremgangsmåde til oprensning af poloxamerer |