DK405078A - Fremgangsmaade til fremstilling af prostaglandinanaloge - Google Patents

Fremgangsmaade til fremstilling af prostaglandinanaloge

Info

Publication number
DK405078A
DK405078A DK405078A DK405078A DK405078A DK 405078 A DK405078 A DK 405078A DK 405078 A DK405078 A DK 405078A DK 405078 A DK405078 A DK 405078A DK 405078 A DK405078 A DK 405078A
Authority
DK
Denmark
Prior art keywords
prostagland
analog
procedure
production
prostagland analog
Prior art date
Application number
DK405078A
Other languages
Danish (da)
English (en)
Inventor
M Hayashi
K Shimoji
Y Arai
Original Assignee
Ono Pharmaceutical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ono Pharmaceutical Co filed Critical Ono Pharmaceutical Co
Publication of DK405078A publication Critical patent/DK405078A/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
    • C07D307/935—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
    • C07D307/935—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
    • C07D307/937—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans with hydrocarbon or substituted hydrocarbon radicals directly attached in position 2, e.g. prostacyclins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F1/00—Compounds containing elements of Groups 1 or 11 of the Periodic Table
    • C07F1/02—Lithium compounds

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Materials Engineering (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
DK405078A 1977-09-16 1978-09-14 Fremgangsmaade til fremstilling af prostaglandinanaloge DK405078A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP52110504A JPS6022710B2 (ja) 1977-09-16 1977-09-16 プロスタグランジン類似化合物

Publications (1)

Publication Number Publication Date
DK405078A true DK405078A (da) 1979-03-17

Family

ID=14537436

Family Applications (3)

Application Number Title Priority Date Filing Date
DK405078A DK405078A (da) 1977-09-16 1978-09-14 Fremgangsmaade til fremstilling af prostaglandinanaloge
DK620289A DK620289D0 (da) 1977-09-16 1989-12-08 Analogifremgangsmaade og udgangsmateriale til fremstilling af prostaglandin e1-analoge samt cyclodextrinchlathrater og ikke-toksiske salte deraf
DK620189A DK620189A (da) 1977-09-16 1989-12-08 Prostaglandin e1-analoge og cyclodextrinchlathrater og ikke-toksiske salte deraf samt middel indeholende dem

Family Applications After (2)

Application Number Title Priority Date Filing Date
DK620289A DK620289D0 (da) 1977-09-16 1989-12-08 Analogifremgangsmaade og udgangsmateriale til fremstilling af prostaglandin e1-analoge samt cyclodextrinchlathrater og ikke-toksiske salte deraf
DK620189A DK620189A (da) 1977-09-16 1989-12-08 Prostaglandin e1-analoge og cyclodextrinchlathrater og ikke-toksiske salte deraf samt middel indeholende dem

Country Status (19)

Country Link
US (2) US4215142A (de)
JP (1) JPS6022710B2 (de)
AU (1) AU527940B2 (de)
BE (1) BE870531A (de)
CA (1) CA1119169A (de)
CH (2) CH638492A5 (de)
DE (2) DE2840032C2 (de)
DK (3) DK405078A (de)
FR (2) FR2403333A1 (de)
GB (2) GB2079268B (de)
HK (1) HK82185A (de)
HU (1) HU182553B (de)
IE (1) IE47439B1 (de)
IT (2) IT1192580B (de)
LU (1) LU80235A1 (de)
MY (1) MY8600652A (de)
NL (2) NL184467C (de)
SG (1) SG58485G (de)
ZA (1) ZA785230B (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2834248A1 (de) * 1978-08-04 1980-02-28 Hoechst Ag Neue prostaglandinderivate in der delta 2-pgf tief 2 und delta 2-pge tief 2 -reihe
DE2913856A1 (de) * 1979-04-06 1980-10-23 Hoechst Ag Neue prostaglandinderivate in der 6-keto-pge tief 1 -reihe
US4443478A (en) * 1981-06-29 1984-04-17 Ono Pharmaceutical Co., Ltd. Prostaglandin analogues
JPS58164512A (ja) * 1982-03-25 1983-09-29 Ono Pharmaceut Co Ltd プロスタグランジン類似化合物を有効成分として含有する肝臓疾患治療剤
JPS59163365A (ja) * 1983-03-08 1984-09-14 Ono Pharmaceut Co Ltd プロスタグランジン類似化合物
DE3401542A1 (de) * 1984-01-18 1985-08-01 Merck Patent Gmbh, 6100 Darmstadt Schwefelhaltige 6-ketoprostaglandine
JPS60181068A (ja) * 1984-02-29 1985-09-14 Teijin Ltd ６−置換プロスタグランジンｅ↓１類およびその製造法
JPS6130554A (ja) * 1984-07-23 1986-02-12 Ono Pharmaceut Co Ltd プロスタグランジン類似化合物のある特定の立体配置を有する異性体及びそれらを有効成分として含有する治療剤
US4755531A (en) * 1986-08-11 1988-07-05 Syntex (U.S.A.) Inc. Thiol esters of 4,5-allenyl prostaglandins and use thereof as antigastric secretion agents
US5219885A (en) * 1987-02-16 1993-06-15 Froelich Juergen Prostaglandin E1 derivatives as pharmaceutically active agents, and pharmaceutical compositions containing these compounds, especially for transcutaneous administration
DE3704825A1 (de) * 1987-02-16 1988-08-25 Froelich Juergen Prostaglandin e1-derivate als pharmazeutische wirkstoffe und diese verbindungen enthaltende arzneimittel insbesondere zur transkutanen anwendung
DE3708537A1 (de) * 1987-03-13 1988-09-22 Schering Ag 6-oxoprostaglandin-e-derivate, verfahren zu ihrer herstellung und ihre pharmazeutische verwendung
JPS63202544U (de) * 1987-06-22 1988-12-27
US5078195A (en) * 1989-01-10 1992-01-07 Schoen Siegfried J Double-walled pleated curtain
US5234954A (en) * 1989-07-27 1993-08-10 K.K. Ueno Seiyaku Oyo Kenkyujo Treatment of hyperlipidemia with 15-keto-prostaglandin compounds
US6576663B2 (en) 1999-12-22 2003-06-10 Alcon, Inc. 6-Keto prostaglandin F1α and analogs for treating dry eye
CA2784933A1 (en) * 2009-12-18 2011-06-23 Apotex Pharmachem Inc. Processes for the purification of lubiprostone

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4034003A (en) * 1974-04-11 1977-07-05 Ono Pharmaceutical Co., Ltd. 15-Cycloalkyl-prostaglandins
IL51189A (en) * 1976-02-04 1985-08-30 Upjohn Co Prostaglandin analogs
US4171447A (en) * 1976-12-30 1979-10-16 The Upjohn Company Tri-halo prostaglandin intermediates
AU511711B2 (en) * 1976-12-30 1980-09-04 Upjohn Company, The 6-Oxo and 5, 6-Dihalo prostaglandin analogues
US4124601A (en) * 1976-12-30 1978-11-07 The Upjohn Company Certain 5-halo-6,9α-epoxy-14-bromo(or chloro)-PGF1 compounds

Also Published As

Publication number Publication date
DK620289A (da) 1989-12-08
US4215142A (en) 1980-07-29
DE2840032C2 (de) 1983-12-22
IE781857L (en) 1979-03-16
AU3988678A (en) 1980-03-20
GB2006753B (en) 1982-08-04
NL8203068A (nl) 1982-12-01
DE2858094C2 (de) 1986-03-06
NL184467C (nl) 1989-08-01
IT1192580B (it) 1988-04-20
CH635318A5 (fr) 1983-03-31
US4278688A (en) 1981-07-14
CH638492A5 (fr) 1983-09-30
FR2453851A1 (fr) 1980-11-07
GB2006753A (en) 1979-05-10
CA1119169A (en) 1982-03-02
DK620289D0 (da) 1989-12-08
ZA785230B (en) 1979-08-29
DE2840032A1 (de) 1979-03-29
JPS5444639A (en) 1979-04-09
AU527940B2 (en) 1983-03-31
DK620189D0 (da) 1989-12-08
BE870531A (fr) 1979-03-15
HU182553B (en) 1984-02-28
NL7809368A (nl) 1979-03-20
FR2403333A1 (fr) 1979-04-13
NL184467B (nl) 1989-03-01
JPS6022710B2 (ja) 1985-06-03
LU80235A1 (fr) 1979-06-01
IT7827773A0 (it) 1978-09-15
HK82185A (en) 1985-11-01
IE47439B1 (en) 1984-03-21
SG58485G (en) 1986-08-01
IT8619809A0 (it) 1986-03-19
DK620189A (da) 1989-12-08
GB2079268B (en) 1982-08-11
GB2079268A (en) 1982-01-20
MY8600652A (en) 1986-12-31
FR2403333B1 (de) 1982-05-07
IT1213051B (it) 1989-12-07
FR2453851B1 (fr) 1985-10-25

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