DK400284A - 3-(piperidinyl)- og 3-(pyrrolidinyl)-1h-indazoler eller salte deraf, deres fremstilling og deres anvendelse som laegemidler - Google Patents
3-(piperidinyl)- og 3-(pyrrolidinyl)-1h-indazoler eller salte deraf, deres fremstilling og deres anvendelse som laegemidler Download PDFInfo
- Publication number
- DK400284A DK400284A DK400284A DK400284A DK400284A DK 400284 A DK400284 A DK 400284A DK 400284 A DK400284 A DK 400284A DK 400284 A DK400284 A DK 400284A DK 400284 A DK400284 A DK 400284A
- Authority
- DK
- Denmark
- Prior art keywords
- indazoles
- pyrrolidinyl
- piperidinyl
- medicines
- salts
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/30—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by doubly bound oxygen or sulfur atoms or by two oxygen or sulfur atoms singly bound to the same carbon atom
- C07D211/32—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by doubly bound oxygen or sulfur atoms or by two oxygen or sulfur atoms singly bound to the same carbon atom by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurosurgery (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Neurology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US52508883A | 1983-08-22 | 1983-08-22 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DK400284D0 DK400284D0 (da) | 1984-08-21 |
| DK400284A true DK400284A (da) | 1985-02-23 |
Family
ID=24091865
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK400284A DK400284A (da) | 1983-08-22 | 1984-08-21 | 3-(piperidinyl)- og 3-(pyrrolidinyl)-1h-indazoler eller salte deraf, deres fremstilling og deres anvendelse som laegemidler |
Country Status (17)
| Country | Link |
|---|---|
| EP (1) | EP0135781B1 (ja) |
| JP (1) | JPS60100573A (ja) |
| KR (1) | KR880002356B1 (ja) |
| AT (1) | ATE47139T1 (ja) |
| AU (1) | AU575846B2 (ja) |
| CA (1) | CA1292232C (ja) |
| DE (1) | DE3480091D1 (ja) |
| DK (1) | DK400284A (ja) |
| ES (2) | ES8601964A1 (ja) |
| FI (1) | FI82242C (ja) |
| GR (1) | GR80160B (ja) |
| HU (1) | HU198036B (ja) |
| IL (1) | IL72743A (ja) |
| NZ (1) | NZ209279A (ja) |
| PH (1) | PH22032A (ja) |
| PT (1) | PT79110B (ja) |
| ZA (1) | ZA846485B (ja) |
Families Citing this family (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0181793B1 (fr) * | 1984-10-16 | 1988-07-27 | Synthelabo | Dérivés de pipéridine, leur préparation et leur application en thérapeutique |
| EP0192935B1 (en) * | 1985-01-23 | 1991-02-27 | Hoechst-Roussel Pharmaceuticals Incorporated | 3-(piperidinyl)-1h-indazoles a process for their preparation and their use as medicaments |
| US4999356A (en) * | 1987-08-07 | 1991-03-12 | Hoechst-Roussel Pharmaceuticals, Inc. | 1-phenyl-3-(1-piperazinyl)-1H-indazoles |
| GB8811299D0 (en) * | 1988-05-12 | 1988-06-15 | Grayshan R | Indazole derivatives |
| NZ230045A (en) | 1988-08-05 | 1990-11-27 | Janssen Pharmaceutica Nv | 3-piperazinylbenzazole derivatives and pharmaceutical compositions |
| US5015740A (en) * | 1988-08-05 | 1991-05-14 | Janssen Pharmaceutica N.V. | Antipsychotic 3-piperazinylbenzazole derivatives |
| US4957916A (en) * | 1988-08-05 | 1990-09-18 | Janssen Pharmaceutica N.V. | Antipsychotic 3-piperazinylbenzazole derivatives |
| IL90879A0 (en) * | 1988-09-02 | 1990-02-09 | Janssen Pharmaceutica Nv | 3-piperidinyl-indazole derivatives,their preparation and antihypertensive compositions containing them |
| DK0402644T3 (da) * | 1989-05-19 | 1996-01-02 | Hoechst Roussel Pharma | N-(Aryloxyalkyl)-heteroarylpiperidiner og -heteroarylpiperaziner, fremgangsmåde til deres fremstilli ng samt deres anvendelse som medikamenter |
| US5364866A (en) * | 1989-05-19 | 1994-11-15 | Hoechst-Roussel Pharmaceuticals, Inc. | Heteroarylpiperidines, pyrrolidines and piperazines and their use as antipsychotics and analetics |
| US5561128A (en) * | 1989-05-19 | 1996-10-01 | Hoechst-Roussel Pharmaceuticals, Inc. | N-[(4-(heteroaryl)-1-piperidinyl)alkyl]-10,11-dihydro-5H-dibenz[B,F]azepines and related compounds and their therapeutic utility |
| US5776963A (en) * | 1989-05-19 | 1998-07-07 | Hoechst Marion Roussel, Inc. | 3-(heteroaryl)-1- (2,3-dihydro-1h-isoindol-2-yl)alkyl!pyrrolidines and 3-(heteroaryl)-1- (2,3-dihydro-1h-indol-1-yl)alkyl!pyrrolidines and related compounds and their therapeutic untility |
| DK181190D0 (da) * | 1990-07-30 | 1990-07-30 | Lundbeck & Co As H | 3-aryl-indol- eller 3-aryl-indazolderivater |
| US5051430A (en) * | 1990-09-10 | 1991-09-24 | Hoechst-Roussel Pharmaceuticals Incorporated | 3-(1H-indazol-3-yl)-4-pyridinamines |
| NZ243065A (en) * | 1991-06-13 | 1995-07-26 | Lundbeck & Co As H | Piperidine derivatives and pharmaceutical compositions |
| DK55192D0 (da) * | 1992-04-28 | 1992-04-28 | Lundbeck & Co As H | 1-piperazino-1,2-dihydroindenderivater |
| ES2133416T3 (es) * | 1992-10-23 | 1999-09-16 | Merck Sharp & Dohme | Ligandos de subtipos de receptores de dopamina. |
| JPH08502958A (ja) * | 1992-10-23 | 1996-04-02 | メルク シヤープ エンド ドーム リミテツド | ドーパミンレセプターサブタイプリガンド |
| DE4414113A1 (de) * | 1994-04-22 | 1995-10-26 | Merck Patent Gmbh | 3-Indolylpiperidine |
| US5668148A (en) * | 1995-04-20 | 1997-09-16 | Merck & Co., Inc. | Alpha1a adrenergic receptor antagonists |
| AU736303B2 (en) | 1996-10-14 | 2001-07-26 | Bayer Aktiengesellschaft | New heterocyclylmethyl-substituted pyrazol derivates |
| FR2767827A1 (fr) * | 1997-09-03 | 1999-02-26 | Adir | Nouveaux derives de l'indole et de l'indazole, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
| IL126745A (en) * | 1997-11-04 | 2003-09-17 | Pfizer Prod Inc | Methods of preparing 4-cyano-4- (substituted indazole) cyclohexanecarboxylic acids useful as pde4 inhibitors |
| US6133290A (en) * | 1998-07-31 | 2000-10-17 | Eli Lilly And Company | 5-HT1F agonists |
| WO2004069828A1 (ja) * | 2003-02-04 | 2004-08-19 | Mitsubishi Pharma Corporation | ピペリジン化合物およびその医薬用途 |
| BRPI0418255A (pt) * | 2003-12-31 | 2007-04-17 | Warner Lambert Co | derivados de piperazina e piperidina n-substituìdos |
| ATE460415T1 (de) | 2004-11-29 | 2010-03-15 | Warner Lambert Co | Therapeutische pyrazoloä3,4-büpyridine und - indazole |
| UY32174A (es) * | 2008-10-14 | 2010-05-31 | Astrazeneca Ab | Nuevos heterociclos sustituidos, composiciones farmaceuticas conteniendolos, procedimientos de preparacion y aplicaciones |
| EP2790687B1 (en) | 2011-12-16 | 2018-08-29 | Poseida Therapeutics, Inc. | Trpc4 modulators for use in the treatment or prevention of pain |
| JP2015214492A (ja) * | 2012-09-07 | 2015-12-03 | 大日本住友製薬株式会社 | ３−（４−ピペリジル）−インダゾール誘導体 |
| KR102615821B1 (ko) * | 2017-04-11 | 2023-12-21 | 선샤인 레이크 파르마 컴퍼니 리미티드 | 불소-치환된 인다졸 화합물 및 이의 용도 |
-
1984
- 1984-08-15 HU HU843095A patent/HU198036B/hu not_active IP Right Cessation
- 1984-08-17 EP EP84109800A patent/EP0135781B1/en not_active Expired
- 1984-08-17 DE DE8484109800T patent/DE3480091D1/de not_active Expired
- 1984-08-17 AT AT84109800T patent/ATE47139T1/de not_active IP Right Cessation
- 1984-08-20 PH PH31122A patent/PH22032A/en unknown
- 1984-08-20 ES ES535289A patent/ES8601964A1/es not_active Expired
- 1984-08-20 NZ NZ209279A patent/NZ209279A/en unknown
- 1984-08-20 FI FI843281A patent/FI82242C/fi not_active IP Right Cessation
- 1984-08-21 DK DK400284A patent/DK400284A/da not_active Application Discontinuation
- 1984-08-21 CA CA000461452A patent/CA1292232C/en not_active Expired - Lifetime
- 1984-08-21 AU AU32250/84A patent/AU575846B2/en not_active Ceased
- 1984-08-21 ZA ZA846485A patent/ZA846485B/xx unknown
- 1984-08-21 JP JP59172528A patent/JPS60100573A/ja active Granted
- 1984-08-21 PT PT79110A patent/PT79110B/pt not_active IP Right Cessation
- 1984-08-21 KR KR1019840005046A patent/KR880002356B1/ko not_active IP Right Cessation
- 1984-08-21 GR GR80160A patent/GR80160B/el unknown
- 1984-08-28 IL IL72743A patent/IL72743A/xx unknown
-
1985
- 1985-05-16 ES ES543206A patent/ES543206A0/es active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| KR850001748A (ko) | 1985-04-01 |
| AU575846B2 (en) | 1988-08-11 |
| PT79110A (en) | 1984-09-01 |
| ES535289A0 (es) | 1985-11-01 |
| DE3480091D1 (en) | 1989-11-16 |
| JPH051792B2 (ja) | 1993-01-11 |
| FI82242B (fi) | 1990-10-31 |
| DK400284D0 (da) | 1984-08-21 |
| FI843281A0 (fi) | 1984-08-20 |
| JPS60100573A (ja) | 1985-06-04 |
| IL72743A (en) | 1989-01-31 |
| IL72743A0 (en) | 1984-11-30 |
| AU3225084A (en) | 1985-02-28 |
| FI82242C (fi) | 1991-02-11 |
| ATE47139T1 (de) | 1989-10-15 |
| ZA846485B (en) | 1985-03-27 |
| CA1292232C (en) | 1991-11-19 |
| EP0135781A1 (en) | 1985-04-03 |
| HU198036B (en) | 1989-07-28 |
| FI843281A (fi) | 1985-02-23 |
| KR880002356B1 (ko) | 1988-10-29 |
| NZ209279A (en) | 1988-05-30 |
| ES8603867A1 (es) | 1986-01-01 |
| EP0135781B1 (en) | 1989-10-11 |
| HUT37139A (en) | 1985-11-28 |
| GR80160B (en) | 1984-12-19 |
| PH22032A (en) | 1988-05-13 |
| ES8601964A1 (es) | 1985-11-01 |
| PT79110B (en) | 1986-09-15 |
| ES543206A0 (es) | 1986-01-01 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DK400284A (da) | 3-(piperidinyl)- og 3-(pyrrolidinyl)-1h-indazoler eller salte deraf, deres fremstilling og deres anvendelse som laegemidler | |
| DK15589D0 (da) | Kemiske forbindelser | |
| FI88629B (fi) | Beklaednad foer en arkformningsdel av en pappersmaskin med ytterligare, loepande tvaertraodar som har en stoerre modellaengd | |
| FI900552A0 (fi) | Uudet piperidinyylifunktionaaliset yhdisteet, niiden valmistusmenetelmä ja niiden käyttö polymeerien UV-stabilisaattorina | |
| ES529314A0 (es) | Procedimiento para la preparacion de 3-(1-sustituido-4-piperidil)-1, 2-bencisoxazoles | |
| IT1130765B (it) | Procedimento per il trattamento termico,in particolare per la essiccazione o rispettivamente per la calcinazione | |
| EP0127167A3 (en) | 3-(4-piperidinyl)-1,2-benzisothiazoles and derivates, a process for their preparation and their use as medicaments | |
| ATA78476A (de) | Enossales implantat zur befestigung von festsitzendem zahnersatz, vorrichtung zum passgenauen herstellen von ausfraesungen dafuer sowie versenkinstrument zum versenken des implantats | |
| NO904576L (no) | Aminopyridinylaminofenol og beslektede forbindelser, mellomprodukter, fremgangsmaate for deres fremstilling og anvendelse som medikamenter. | |
| DK442183A (da) | Thiatriazin-derivater, fremgangsmaader til fremstilling deraf og deres anvendelse som laegemidler | |
| DK591687D0 (da) | Pyrazoliner, fremstilling deraf og anvendelse deraf som middel med insekticid og akarizid virkning | |
| DE58902310D1 (de) | Tetrahydropyridin-derivate. | |
| NO860227L (no) | 3-(piperidinyl)- og - 3-(pyrrolidinyl)-1h-indazoler og fremgangsmaate for fremstilling derav. | |
| ATE2068T1 (de) | Verwendung von s-benzyl-3-benzylthiopropionthioat in arzneimitteln. | |
| DK179683D0 (da) | N-sulfenylerede carbamater, fremgangsmade til fremstilling heraf og deres anvendelse som skadedyrbekaempelsesmiddel | |
| DK560887D0 (da) | Piperidin forbindelser, deres fremstilling og anvendelse | |
| DK550383A (da) | Perfluorcarbonemulsioner, fremgangsmaade til fremstilling heraf og deres anvendelse som laegemidler |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ATS | Application withdrawn |