DK3990033T3 - Frysetørret sammensætning til fremstilling af kalibrerede gasfyldte mikrovesikler - Google Patents
Frysetørret sammensætning til fremstilling af kalibrerede gasfyldte mikrovesikler Download PDFInfo
- Publication number
- DK3990033T3 DK3990033T3 DK20761497.5T DK20761497T DK3990033T3 DK 3990033 T3 DK3990033 T3 DK 3990033T3 DK 20761497 T DK20761497 T DK 20761497T DK 3990033 T3 DK3990033 T3 DK 3990033T3
- Authority
- DK
- Denmark
- Prior art keywords
- freeze
- manufacture
- dried composition
- filled microvesicles
- calibrated gas
- Prior art date
Links
- 238000004519 manufacturing process Methods 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/22—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations
- A61K49/222—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations characterised by a special physical form, e.g. emulsions, liposomes
- A61K49/223—Microbubbles, hollow microspheres, free gas bubbles, gas microspheres
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Radiology & Medical Imaging (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Physics & Mathematics (AREA)
- Acoustics & Sound (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Medicinal Preparation (AREA)
- Confectionery (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP19182226 | 2019-06-25 | ||
| PCT/EP2020/067756 WO2020260423A1 (en) | 2019-06-25 | 2020-06-24 | Freeze-dried composition for preparing calibrated gas-filled microvesicles |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK3990033T3 true DK3990033T3 (da) | 2023-12-18 |
Family
ID=67070596
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK20761497.5T DK3990033T3 (da) | 2019-06-25 | 2020-06-24 | Frysetørret sammensætning til fremstilling af kalibrerede gasfyldte mikrovesikler |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20220409749A1 (da) |
| EP (1) | EP3990033B1 (da) |
| JP (1) | JP2022538769A (da) |
| CN (1) | CN114007656A (da) |
| DK (1) | DK3990033T3 (da) |
| ES (1) | ES2967371T3 (da) |
| WO (1) | WO2020260423A1 (da) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA3215532A1 (en) | 2021-07-14 | 2023-01-19 | Anne LASSUS | Cationic calibrated-size gas-filled microvesicles |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE237362T1 (de) | 1996-02-19 | 2003-05-15 | Amersham Health As | Thermostabilisiertes kontrastmittel |
| US9364569B2 (en) * | 2003-02-04 | 2016-06-14 | Bracco Suisse S.A. | Ultrasound contrast agents and process for the preparation thereof |
| GB201405735D0 (en) | 2014-03-31 | 2014-05-14 | Ge Healthcare As | Ultrasound precursor preparation method |
| CN105999314B (zh) * | 2016-07-11 | 2018-12-18 | 四川省人民医院 | 一种超声造影剂及其制备方法 |
| EP3506882B1 (en) | 2016-08-30 | 2022-01-12 | Bracco Suisse SA | Preparation of size-controlled microparticles |
-
2020
- 2020-06-24 ES ES20761497T patent/ES2967371T3/es active Active
- 2020-06-24 EP EP20761497.5A patent/EP3990033B1/en active Active
- 2020-06-24 JP JP2021573452A patent/JP2022538769A/ja active Pending
- 2020-06-24 DK DK20761497.5T patent/DK3990033T3/da active
- 2020-06-24 WO PCT/EP2020/067756 patent/WO2020260423A1/en unknown
- 2020-06-24 CN CN202080046128.5A patent/CN114007656A/zh active Pending
- 2020-06-24 US US17/620,170 patent/US20220409749A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| CN114007656A (zh) | 2022-02-01 |
| EP3990033B1 (en) | 2023-12-06 |
| ES2967371T3 (es) | 2024-04-30 |
| EP3990033A1 (en) | 2022-05-04 |
| JP2022538769A (ja) | 2022-09-06 |
| WO2020260423A1 (en) | 2020-12-30 |
| US20220409749A1 (en) | 2022-12-29 |
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