DK384785A - Optisk aktive, substituerede 1,4-dihydropyridiner eller syreadditionssalte deraf, deres fremstilling og anvendelse som calciumantagonister - Google Patents

Optisk aktive, substituerede 1,4-dihydropyridiner eller syreadditionssalte deraf, deres fremstilling og anvendelse som calciumantagonister Download PDF

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Publication number
DK384785A
DK384785A DK384785A DK384785A DK384785A DK 384785 A DK384785 A DK 384785A DK 384785 A DK384785 A DK 384785A DK 384785 A DK384785 A DK 384785A DK 384785 A DK384785 A DK 384785A
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DK
Denmark
Prior art keywords
dihydropyridines
substituted
preparation
acid addition
addition salts
Prior art date
Application number
DK384785A
Other languages
Danish (da)
English (en)
Other versions
DK384785D0 (da
Inventor
Karl Schoenafinger
Helmut Bohn
Piero A Martorana
Rolf-Eberhard Nitz
Original Assignee
Cassella Farbwerke Mainkur Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Cassella Farbwerke Mainkur Ag filed Critical Cassella Farbwerke Mainkur Ag
Publication of DK384785D0 publication Critical patent/DK384785D0/da
Publication of DK384785A publication Critical patent/DK384785A/da

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/12Drugs for disorders of the metabolism for electrolyte homeostasis
    • A61P3/14Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/80Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D211/84Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
    • C07D211/90Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D493/00Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/04Ortho-condensed systems

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Endocrinology (AREA)
  • Rheumatology (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK384785A 1984-08-24 1985-08-23 Optisk aktive, substituerede 1,4-dihydropyridiner eller syreadditionssalte deraf, deres fremstilling og anvendelse som calciumantagonister DK384785A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19843431152 DE3431152A1 (de) 1984-08-24 1984-08-24 Verfahren zur herstellung optisch aktiver, substituierter 1,4-dihydropyridine und ihre verwendung als arzneimittel

Publications (2)

Publication Number Publication Date
DK384785D0 DK384785D0 (da) 1985-08-23
DK384785A true DK384785A (da) 1986-02-25

Family

ID=6243791

Family Applications (1)

Application Number Title Priority Date Filing Date
DK384785A DK384785A (da) 1984-08-24 1985-08-23 Optisk aktive, substituerede 1,4-dihydropyridiner eller syreadditionssalte deraf, deres fremstilling og anvendelse som calciumantagonister

Country Status (14)

Country Link
US (1) US4760147A (ko)
EP (1) EP0172509A3 (ko)
JP (1) JPS6165883A (ko)
KR (1) KR870002135A (ko)
AU (1) AU4660685A (ko)
CA (1) CA1257255A (ko)
DE (1) DE3431152A1 (ko)
DK (1) DK384785A (ko)
ES (1) ES8609314A1 (ko)
FI (1) FI853164L (ko)
GR (1) GR852034B (ko)
HU (1) HU197325B (ko)
PL (2) PL255090A1 (ko)
ZA (1) ZA856402B (ko)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6191185A (ja) * 1984-10-11 1986-05-09 Sumitomo Seiyaku Kk 新規なオキサジアゾリル−1,4−ジヒドロピリジン誘導体
DE3443179A1 (de) * 1984-11-27 1986-05-28 Cassella Ag, 6000 Frankfurt 1,4-dihydropyridine, verfahren zu ihrer herstellung und ihre verwendung
US4988384A (en) * 1987-02-09 1991-01-29 Monsanto Company Penta-substituted pyridine compounds, herbicidal compositions and herbicidal method of use
WO1988007525A1 (en) * 1987-03-27 1988-10-06 Byk Gulden Lomberg Chemische Fabrik Gmbh 1,4-dihydropyridine enantiomers
WO2005020685A2 (en) * 2003-08-29 2005-03-10 Luzenac America, Inc. Composition and method for crop protection

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2847236A1 (de) * 1978-10-31 1980-05-14 Bayer Ag Neue dihydropyridine mit substituierten estergruppierungen, mehrer verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel
DE2935451A1 (de) * 1979-09-01 1981-03-19 Bayer Ag, 5090 Leverkusen Optisch aktive 1,4-dihydropyridine, verfahren zu ihrer herstellung und ihre verwendung als arneimittel
NZ201395A (en) * 1981-07-30 1987-02-20 Bayer Ag Pharmaceutical compositions containing 1,4-dihydropyridines and certain of these dihydropyridines
US4497808A (en) * 1981-12-30 1985-02-05 Ciba-Geigy Corporation N-Oxide compounds useful in the treatment of cardiovascular ailments
FR2528431B1 (fr) * 1982-06-15 1986-01-10 Sandoz Sa Nouveaux derives de la 1,4-dihydropyridine, leur preparation et leur utilisation comme medicaments
DE3247118A1 (de) * 1982-12-20 1984-06-20 Cassella Ag, 6000 Frankfurt Neue substituierte 1,4-dihydropyridine, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
DE3248548A1 (de) * 1982-12-29 1984-07-05 Heinrich Mack Nachf., 7918 Illertissen Acylderivate von 1,4:3,6-dianhydro-hexiten, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
IT1200928B (it) * 1983-07-11 1989-01-27 Malesci Sas Procedimento per la preparazione di 1-piridil-alchil-4-aril piperazine utili per la loro attivita' antiipertensiva,lloro separazione nei relativi antipodi ottici e composti stereoisomeri cosi' ottenuti

Also Published As

Publication number Publication date
FI853164L (fi) 1986-02-25
ES546387A0 (es) 1986-07-16
EP0172509A3 (de) 1988-01-07
EP0172509A2 (de) 1986-02-26
ES8609314A1 (es) 1986-07-16
US4760147A (en) 1988-07-26
CA1257255A (en) 1989-07-11
HU197325B (en) 1989-03-28
ZA856402B (en) 1986-04-30
AU4660685A (en) 1986-03-20
FI853164A0 (fi) 1985-08-16
JPS6165883A (ja) 1986-04-04
PL260922A1 (en) 1987-02-09
PL255090A1 (en) 1986-12-30
KR870002135A (ko) 1987-03-30
GR852034B (ko) 1985-12-18
DE3431152A1 (de) 1986-03-06
HUT40648A (en) 1987-01-28
DK384785D0 (da) 1985-08-23

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