DK3842423T3 - 3-azabicyclo[3,1,1]heptanderivat og farmaceutisk sammensætning omfattende denne - Google Patents
3-azabicyclo[3,1,1]heptanderivat og farmaceutisk sammensætning omfattende denne Download PDFInfo
- Publication number
- DK3842423T3 DK3842423T3 DK19864868.5T DK19864868T DK3842423T3 DK 3842423 T3 DK3842423 T3 DK 3842423T3 DK 19864868 T DK19864868 T DK 19864868T DK 3842423 T3 DK3842423 T3 DK 3842423T3
- Authority
- DK
- Denmark
- Prior art keywords
- heptan
- azabicyclo
- derivative
- pharmaceutical composition
- pharmaceutical
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/444—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring heteroatom, e.g. amrinone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR1020180115191A KR102558308B1 (ko) | 2018-09-27 | 2018-09-27 | 3-아자바이사이클로[3,1,1]헵탄 유도체 및 이를 포함하는 약제학적 조성물 |
| PCT/KR2019/012522 WO2020067735A1 (ko) | 2018-09-27 | 2019-09-26 | 3-아자바이사이클로[3,1,1]헵탄 유도체 및 이를 포함하는 약제학적 조성물 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK3842423T3 true DK3842423T3 (da) | 2023-05-30 |
Family
ID=69949388
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK19864868.5T DK3842423T3 (da) | 2018-09-27 | 2019-09-26 | 3-azabicyclo[3,1,1]heptanderivat og farmaceutisk sammensætning omfattende denne |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20220033381A1 (da) |
| EP (1) | EP3842423B1 (da) |
| JP (1) | JP7222590B2 (da) |
| KR (1) | KR102558308B1 (da) |
| CN (1) | CN112789271B (da) |
| DK (1) | DK3842423T3 (da) |
| WO (1) | WO2020067735A1 (da) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP4083034A4 (en) | 2019-12-24 | 2023-12-06 | Hangzhou Zhongmeihuadong Pharmaceutical Co., Ltd. | ASSOCIATION WITH CHAD-INHIBITING EFFECT |
| US20230203008A1 (en) * | 2020-04-20 | 2023-06-29 | Lg Chem, Ltd. | 3-azabicycloalkyl derivative and pharmaceutical composition containing same |
| CN111423420A (zh) * | 2020-04-30 | 2020-07-17 | 广州博济医药生物技术股份有限公司 | 作为己酮糖激酶抑制剂的并环化合物 |
| CN116635377A (zh) * | 2020-12-25 | 2023-08-22 | 四川海思科制药有限公司 | 己酮糖激酶抑制剂及其用途 |
| AU2022252182A1 (en) | 2021-03-29 | 2023-09-28 | Gilead Sciences, Inc. | Khk inhibitors |
| WO2023121378A1 (ko) * | 2021-12-24 | 2023-06-29 | 주식회사 엘지화학 | (s)-2-(2-메틸아제티딘-1-일)피리미딘 유도체 및 이를 포함하는 약제학적 조성물 |
| WO2023151473A1 (zh) * | 2022-02-09 | 2023-08-17 | 上海研健新药研发有限公司 | 一种khk抑制剂，其制备方法和应用 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8822447B2 (en) | 2010-04-22 | 2014-09-02 | Janssen Pharmaceutica Nv | Indazole compounds useful as ketohexokinase inhibitors |
| EA027809B1 (ru) | 2012-07-27 | 2017-09-29 | Биоген Айдек Ма Инк. | Соединения, которые являются s1p-модулирующими агентами и/или atx-модулирующими агентами |
| US10329289B2 (en) | 2015-12-23 | 2019-06-25 | Merck Sharp & Dohme Corp. | 6,7-dihydro-5H-pyrrolo[3,4-B]pyridin-5-one allosteric modulators of the M4 muscarinic acetylcholine receptor |
| SG11201804363UA (en) * | 2015-12-29 | 2018-07-30 | Pfizer | Substituted 3-azabicyclo[3.1.0]hexanes as ketohexokinase inhibitors |
| WO2018021977A1 (en) | 2016-07-29 | 2018-02-01 | Agency For Science, Technology And Research | Glycine metabolism modulators and uses thereof |
| JOP20190077A1 (ar) | 2016-10-10 | 2019-04-09 | Array Biopharma Inc | مركبات بيرازولو [1، 5-a]بيريدين بها استبدال كمثبطات كيناز ret |
| WO2018137593A1 (en) | 2017-01-25 | 2018-08-02 | Glaxosmithkline Intellectual Property Development Limited | Compounds |
-
2018
- 2018-09-27 KR KR1020180115191A patent/KR102558308B1/ko active IP Right Grant
-
2019
- 2019-09-26 EP EP19864868.5A patent/EP3842423B1/en active Active
- 2019-09-26 US US17/280,353 patent/US20220033381A1/en active Pending
- 2019-09-26 DK DK19864868.5T patent/DK3842423T3/da active
- 2019-09-26 WO PCT/KR2019/012522 patent/WO2020067735A1/ko unknown
- 2019-09-26 JP JP2021517431A patent/JP7222590B2/ja active Active
- 2019-09-26 CN CN201980063486.4A patent/CN112789271B/zh active Active
Also Published As
| Publication number | Publication date |
|---|---|
| EP3842423A1 (en) | 2021-06-30 |
| JP7222590B2 (ja) | 2023-02-15 |
| JP2022502444A (ja) | 2022-01-11 |
| KR102558308B1 (ko) | 2023-07-24 |
| EP3842423A4 (en) | 2021-08-18 |
| CN112789271A (zh) | 2021-05-11 |
| WO2020067735A1 (ko) | 2020-04-02 |
| US20220033381A1 (en) | 2022-02-03 |
| KR20200035720A (ko) | 2020-04-06 |
| EP3842423B1 (en) | 2023-05-17 |
| CN112789271B (zh) | 2023-09-12 |
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