DK3840837T3 - Arginasehæmmere og fremgangsmåder til anvendelse deraf - Google Patents

Arginasehæmmere og fremgangsmåder til anvendelse deraf Download PDF

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Publication number
DK3840837T3
DK3840837T3 DK19758683.7T DK19758683T DK3840837T3 DK 3840837 T3 DK3840837 T3 DK 3840837T3 DK 19758683 T DK19758683 T DK 19758683T DK 3840837 T3 DK3840837 T3 DK 3840837T3
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DK
Denmark
Prior art keywords
methods
arginase inhibitors
arginase
inhibitors
Prior art date
Application number
DK19758683.7T
Other languages
Danish (da)
English (en)
Inventor
Dedong Wu
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Application granted granted Critical
Publication of DK3840837T3 publication Critical patent/DK3840837T3/da

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/69—Boron compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/22—Boron compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
    • C07F5/02—Boron compounds
    • C07F5/025—Boronic and borinic acid compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13—Crystalline forms, e.g. polymorphs

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Inorganic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK19758683.7T 2018-08-22 2019-08-21 Arginasehæmmere og fremgangsmåder til anvendelse deraf DK3840837T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201862721113P 2018-08-22 2018-08-22
PCT/EP2019/072341 WO2020038983A1 (en) 2018-08-22 2019-08-21 Arginase inhibitors and methods of use thereof

Publications (1)

Publication Number Publication Date
DK3840837T3 true DK3840837T3 (da) 2024-06-10

Family

ID=67742403

Family Applications (1)

Application Number Title Priority Date Filing Date
DK19758683.7T DK3840837T3 (da) 2018-08-22 2019-08-21 Arginasehæmmere og fremgangsmåder til anvendelse deraf

Country Status (25)

Country Link
US (1) US11952392B2 (enExample)
EP (2) EP4371614A3 (enExample)
JP (1) JP7441210B2 (enExample)
KR (1) KR102668252B1 (enExample)
CN (1) CN112584900B (enExample)
AU (1) AU2019323663B2 (enExample)
CA (1) CA3109100A1 (enExample)
CL (1) CL2021000430A1 (enExample)
DK (1) DK3840837T3 (enExample)
EA (1) EA202190532A1 (enExample)
ES (1) ES2980252T3 (enExample)
FI (1) FI3840837T3 (enExample)
HR (1) HRP20240694T1 (enExample)
HU (1) HUE066903T2 (enExample)
IL (1) IL280924B2 (enExample)
LT (1) LT3840837T (enExample)
MA (1) MA53427B1 (enExample)
MX (1) MX2021002042A (enExample)
PL (1) PL3840837T3 (enExample)
PT (1) PT3840837T (enExample)
RS (1) RS65608B1 (enExample)
SG (1) SG11202101618PA (enExample)
SI (1) SI3840837T1 (enExample)
SM (1) SMT202400221T1 (enExample)
WO (1) WO2020038983A1 (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2019227607C1 (en) 2018-02-27 2023-07-20 Incyte Corporation Imidazopyrimidines and triazolopyrimidines as A2A / A2B inhibitors
EP3810610A1 (en) 2018-05-18 2021-04-28 Incyte Corporation Fused pyrimidine derivatives as a2a / a2b inhibitors
CN117304191A (zh) 2018-07-05 2023-12-29 因赛特公司 作为a2a/a2b抑制剂的稠合吡嗪衍生物
TWI829857B (zh) 2019-01-29 2024-01-21 美商英塞特公司 作為a2a / a2b抑制劑之吡唑并吡啶及三唑并吡啶
MY206577A (en) * 2019-02-08 2024-12-24 Astrazeneca Ab Arginase inhibitors and methods of use thereof
EP4239652A4 (en) 2020-12-25 2024-06-05 Sumitomo Riko Company Limited Electrically conductive composition, sheet-form flexible electrode using same, and method for producing said electrode

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2560978B1 (en) 2010-04-22 2019-01-30 Mars, Incorporated Inhibitors of arginase and their therapeutic applications
AU2016281620B2 (en) * 2015-06-23 2021-07-22 Calithera Biosciences, Inc. Compositions and methods for inhibiting arginase activity
US11291674B2 (en) * 2016-11-08 2022-04-05 Calithera Biosciences, Inc. Arginase inhibitor combination therapies
WO2018119440A1 (en) 2016-12-22 2018-06-28 Calithera Biosciences, Inc. Compositions and methods for inhibiting arginase activity
SG11202007739XA (en) 2018-02-17 2020-09-29 Astrazeneca Ab Arginase inhibitors and methods of use thereof
US12215116B2 (en) 2018-03-13 2025-02-04 Merck Sharp & Dohme Llc Arginase inhibitors and methods of use
WO2019205979A1 (zh) 2018-04-27 2019-10-31 四川科伦博泰生物医药股份有限公司 非天然氨基酸类衍生物、包含其的药物组合物及其制备方法和用途

Also Published As

Publication number Publication date
EP3840837B1 (en) 2024-03-20
SMT202400221T1 (it) 2024-07-09
JP7441210B2 (ja) 2024-02-29
CA3109100A1 (en) 2020-02-27
EP4371614A2 (en) 2024-05-22
KR102668252B1 (ko) 2024-05-21
US20210332068A1 (en) 2021-10-28
PL3840837T3 (pl) 2024-08-19
MA53427B1 (fr) 2024-06-28
MX2021002042A (es) 2021-04-28
WO2020038983A1 (en) 2020-02-27
HRP20240694T1 (hr) 2024-08-16
KR20210049120A (ko) 2021-05-04
US11952392B2 (en) 2024-04-09
RS65608B1 (sr) 2024-07-31
CN112584900B (zh) 2025-07-15
IL280924B2 (en) 2024-10-01
HUE066903T2 (hu) 2024-09-28
IL280924B1 (en) 2024-06-01
SI3840837T1 (sl) 2024-07-31
EP3840837A1 (en) 2021-06-30
MA53427A (fr) 2021-12-01
JP2021535111A (ja) 2021-12-16
EA202190532A1 (ru) 2021-07-08
AU2019323663B2 (en) 2022-07-14
IL280924A (en) 2021-04-29
SG11202101618PA (en) 2021-03-30
ES2980252T3 (es) 2024-09-30
LT3840837T (lt) 2024-06-10
AU2019323663A1 (en) 2021-04-08
FI3840837T3 (fi) 2024-06-03
EP4371614A3 (en) 2025-09-24
CL2021000430A1 (es) 2021-09-03
PT3840837T (pt) 2024-06-14
CN112584900A (zh) 2021-03-30

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