DK3836906T3 - Ekspanderbar pille til lægemiddelindgivelse - Google Patents

Ekspanderbar pille til lægemiddelindgivelse Download PDF

Info

Publication number
DK3836906T3
DK3836906T3 DK19759058.1T DK19759058T DK3836906T3 DK 3836906 T3 DK3836906 T3 DK 3836906T3 DK 19759058 T DK19759058 T DK 19759058T DK 3836906 T3 DK3836906 T3 DK 3836906T3
Authority
DK
Denmark
Prior art keywords
pill
expandable
drug delivery
drug
delivery
Prior art date
Application number
DK19759058.1T
Other languages
English (en)
Inventor
Yossi Gross
Oz Cabiri
Lital Ben-Shitrit
Original Assignee
Alma Therapeutics Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alma Therapeutics Ltd filed Critical Alma Therapeutics Ltd
Application granted granted Critical
Publication of DK3836906T3 publication Critical patent/DK3836906T3/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4808Preparations in capsules, e.g. of gelatin, of chocolate characterised by the form of the capsule or the structure of the filling; Capsules containing small tablets; Capsules with outer layer for immediate drug release
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0002Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0007Effervescent
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0065Forms with gastric retention, e.g. floating on gastric juice, adhering to gastric mucosa, expanding to prevent passage through the pylorus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2072Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/28Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806Coating materials
    • A61K9/2833Organic macromolecular compounds
    • A61K9/284Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
    • A61K9/2846Poly(meth)acrylates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/28Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806Coating materials
    • A61K9/2833Organic macromolecular compounds
    • A61K9/286Polysaccharides, e.g. gums; Cyclodextrin
    • A61K9/2866Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/28Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806Coating materials
    • A61K9/2833Organic macromolecular compounds
    • A61K9/2873Proteins, e.g. gelatin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M31/00Devices for introducing or retaining media, e.g. remedies, in cavities of the body
    • A61M31/002Devices for releasing a drug at a continuous and controlled rate for a prolonged period of time

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Hematology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Anesthesiology (AREA)
  • Medicinal Preparation (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
DK19759058.1T 2018-08-14 2019-08-13 Ekspanderbar pille til lægemiddelindgivelse DK3836906T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US16/103,420 US10675248B2 (en) 2018-08-14 2018-08-14 Expandable pill
PCT/IL2019/050906 WO2020035857A1 (en) 2018-08-14 2019-08-13 Expandable drug delivery pill

Publications (1)

Publication Number Publication Date
DK3836906T3 true DK3836906T3 (da) 2023-07-03

Family

ID=67766215

Family Applications (1)

Application Number Title Priority Date Filing Date
DK19759058.1T DK3836906T3 (da) 2018-08-14 2019-08-13 Ekspanderbar pille til lægemiddelindgivelse

Country Status (10)

Country Link
US (2) US10675248B2 (da)
EP (1) EP3836906B1 (da)
JP (1) JP7344277B2 (da)
CN (1) CN112867483B (da)
AU (1) AU2019323183A1 (da)
CA (1) CA3109094A1 (da)
DK (1) DK3836906T3 (da)
ES (1) ES2946594T3 (da)
IL (1) IL280777A (da)
WO (1) WO2020035857A1 (da)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3149412A1 (en) * 2019-08-31 2021-03-04 Benjamin D. Pless Opioid overdose rescue device
WO2022026267A2 (en) * 2020-07-30 2022-02-03 Verily Life Sciences Llc Pill with needle delivery system having outwardly expanding mechanical actuation
KR20230142702A (ko) * 2020-12-07 2023-10-11 이피토미 메디칼 엘티디 위내 확장형 장치
CN114588500B (zh) * 2022-02-10 2023-04-11 北京航空航天大学 胃肠道智能化自动弹射给药装置及其制备和给药方法

Family Cites Families (78)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3315660A (en) 1963-08-08 1967-04-25 Carlos A Abella Capsule for insertion in the digestive track
DE2928477C3 (de) 1979-07-14 1982-04-15 Battelle-Institut E.V., 6000 Frankfurt Vorrichtung zur Freisetzung von Substanzen an definierten Orten des Verdauungstraktes
JPS57163309A (en) 1981-04-01 1982-10-07 Olympus Optical Co Ltd Capsule apparatus for medical use
US4767627A (en) 1985-05-29 1988-08-30 Merck & Co., Inc. Drug delivery device which can be retained in the stomach for a controlled period of time
GB8603099D0 (en) 1986-02-07 1986-03-12 Blass K G Gastrointestinal module
US5002772A (en) 1988-05-31 1991-03-26 Pfizer Inc. Gastric retention system for controlled drug release
US5425706A (en) 1989-02-24 1995-06-20 S. I. Scientific Innovations Ltd. Dispensing device particularly useful for dispensing nutritional liquids
IE65045B1 (en) 1990-04-28 1995-10-04 Takeda Chemical Industries Ltd Granulated preparations and method of producing the same
US5170801A (en) 1990-10-02 1992-12-15 Glaxo Inc. Medical capsule device actuated by radio-frequency (rf) signal
US5167626A (en) 1990-10-02 1992-12-01 Glaxo Inc. Medical capsule device actuated by radio-frequency (RF) signal
US5090963A (en) 1990-10-19 1992-02-25 Product Development (Z.G.S.) Ltd. Electrochemically driven metering medicament dispenser
US5217449A (en) 1990-12-11 1993-06-08 Miyarisan Kabushiki Kaisha Medical capsule and apparatus for activating the same
US6235313B1 (en) 1992-04-24 2001-05-22 Brown University Research Foundation Bioadhesive microspheres and their use as drug delivery and imaging systems
US5318557A (en) 1992-07-13 1994-06-07 Elan Medical Technologies Limited Medication administering device
US5637319A (en) 1995-03-01 1997-06-10 Takada; Kanji Controlled-release preparations
IE950366A1 (en) 1995-05-22 1996-11-27 Elan Med Tech Feedback-controlled liquid delivery device
AU7093096A (en) 1995-09-05 1997-03-27 Elan Medical Technologies Limited Chemically driven liquid delivery pumping device
IE77523B1 (en) 1995-09-11 1997-12-17 Elan Med Tech Medicament delivery device
DE19717023C2 (de) 1997-04-23 2003-02-06 Micronas Gmbh Vorrichtung zum Behandeln von malignen, tumorösen Gewebebereichen
US5951538A (en) 1997-08-07 1999-09-14 Ceramatec, Inc. Gas generating device for delivering beneficial agents to a body cavity
IE970782A1 (en) 1997-10-22 1999-05-05 Elan Corp An improved automatic syringe
IL133196A0 (en) 1999-11-29 2001-03-19 Yissum Res Dev Co Gastroretentive controlled release pharmaceutical dosage forms
GB9930000D0 (en) 1999-12-21 2000-02-09 Phaeton Research Ltd An ingestible device
IL177381A0 (en) 2000-03-08 2006-12-10 Given Imaging Ltd A device for in vivo imaging
EP1345646A2 (en) 2000-12-14 2003-09-24 Georgia Tech Research Corporation Microneedle devices and production thereof
US7160258B2 (en) 2001-06-26 2007-01-09 Entrack, Inc. Capsule and method for treating or diagnosing the intestinal tract
US20030153866A1 (en) 2001-11-09 2003-08-14 Long Gary L. Self-propelled, intraluminal device with hollow, cylindrical head and method of use
IL154391A (en) 2002-02-11 2009-05-04 Given Imaging Ltd Self-propelled device
US20050125012A1 (en) * 2002-06-28 2005-06-09 Houser Russell A. Hemostatic patch for treating congestive heart failure
US6776165B2 (en) 2002-09-12 2004-08-17 The Regents Of The University Of California Magnetic navigation system for diagnosis, biopsy and drug delivery vehicles
AU2003282603A1 (en) 2002-10-11 2004-05-04 Depomed Development Ltd Gastro-retentive levodopa delivery form
US20040267240A1 (en) 2003-01-29 2004-12-30 Yossi Gross Active drug delivery in the gastrointestinal tract
KR20050098277A (ko) 2003-01-29 2005-10-11 이-필 파마 리미티드 위장관 내 약물의 능동 송달
US20050058701A1 (en) 2003-01-29 2005-03-17 Yossi Gross Active drug delivery in the gastrointestinal tract
US9700450B2 (en) 2003-07-28 2017-07-11 Baronova, Inc. Devices and methods for gastrointestinal stimulation
US6994095B2 (en) 2003-07-28 2006-02-07 Medventure Associates Iv Pyloric valve corking device and method
US9498366B2 (en) 2003-07-28 2016-11-22 Baronova, Inc. Devices and methods for pyloric anchoring
US8057420B2 (en) 2003-12-09 2011-11-15 Gi Dynamics, Inc. Gastrointestinal implant with drawstring
US8585771B2 (en) 2004-02-26 2013-11-19 Endosphere, Inc. Methods and devices to curb appetite and/or to reduce food intake
US20060045865A1 (en) 2004-08-27 2006-03-02 Spherics, Inc. Controlled regional oral delivery
JP2008522778A (ja) 2004-12-14 2008-07-03 イー−ピル ファーマ リミティド 電気透過性増加を用いた薬物又は物質の局所輸送
US20060142731A1 (en) 2004-12-27 2006-06-29 Jeffrey Brooks Floating gastro-intestinal anchor
US8852083B2 (en) 2005-02-04 2014-10-07 Uti Limited Partnership Self-stabilized encapsulated imaging system
US7699863B2 (en) 2005-03-01 2010-04-20 Tulip Medical Ltd. Bioerodible self-deployable intragastric implants
JP2008540023A (ja) 2005-05-19 2008-11-20 イー−ピル ファーマ リミティド 組織における一酸化窒素生成のための摂取可能デバイス
US7976488B2 (en) 2005-06-08 2011-07-12 Gi Dynamics, Inc. Gastrointestinal anchor compliance
US20070016262A1 (en) 2005-07-13 2007-01-18 Betastim, Ltd. Gi and pancreatic device for treating obesity and diabetes
US8295932B2 (en) 2005-12-05 2012-10-23 Metacure Limited Ingestible capsule for appetite regulation
WO2007086078A2 (en) 2006-01-30 2007-08-02 Panacea Biotec Ltd. Novel pharmaceutical compositions and process of preparation thereof
US8142513B2 (en) 2006-08-23 2012-03-27 Svip 2 Llc Devices and methods for altering eating behavior
BRPI0622039B1 (pt) * 2006-09-26 2020-11-10 Plensat, Llc dispositivos gástricos ingeríveis de qualidade alimentícia
WO2008121409A1 (en) 2007-03-29 2008-10-09 Jaime Vargas Intragastric implant devices
US8226602B2 (en) 2007-03-30 2012-07-24 Reshape Medical, Inc. Intragastric balloon system and therapeutic processes and products
WO2008154450A1 (en) 2007-06-08 2008-12-18 Valentx, Inc. Methods and devices for intragastric support of functional or prosthetic gastrointestinal devices
US8287902B2 (en) 2008-07-23 2012-10-16 Rainbow Medical Ltd. Enhanced-diffusion capsule
US20110066175A1 (en) 2009-05-07 2011-03-17 Rainbow Medical Ltd. Gastric anchor
US8414559B2 (en) 2009-05-07 2013-04-09 Rainbow Medical Ltd. Gastroretentive duodenal pill
US20100286628A1 (en) 2009-05-07 2010-11-11 Rainbow Medical Ltd Gastric anchor
US9017310B2 (en) 2009-10-08 2015-04-28 Palo Alto Research Center Incorporated Transmucosal drug delivery device and method including microneedles
US8759284B2 (en) 2009-12-24 2014-06-24 Rani Therapeutics, Llc Therapeutic agent preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device
CN105999526B (zh) * 2009-12-24 2019-07-05 拉尼医疗有限公司 可吞咽式药剂递送装置和药剂递送方法
US8764733B2 (en) * 2010-12-23 2014-07-01 Rani Therapeutics, Llc Therapeutic agent preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device
US9402807B2 (en) 2010-12-23 2016-08-02 Rani Therapeutics, Llc Therapeutic agent preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device
US9149617B2 (en) 2010-12-23 2015-10-06 Rani Therapeutics, Llc Device, system and methods for the oral delivery of therapeutic compounds
US8846040B2 (en) 2010-12-23 2014-09-30 Rani Therapeutics, Llc Therapeutic agent preparations comprising etanercept for delivery into a lumen of the intestinal tract using a swallowable drug delivery device
US8969293B2 (en) 2010-12-23 2015-03-03 Rani Therapeutics, Llc Therapeutic agent preparations comprising exenatide for delivery into a lumen of the intestinal tract using a swallowable drug delivery device
US9861683B2 (en) 2010-12-23 2018-01-09 Rani Therapeutics, Llc Therapeutic agent preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device
US9259386B2 (en) 2010-12-23 2016-02-16 Rani Therapeutics, Llc Therapeutic preparation comprising somatostatin or somatostatin analogoue for delivery into a lumen of the intestinal tract using a swallowable drug delivery device
US9415004B2 (en) 2010-12-23 2016-08-16 Rani Therapeutics, Llc Therapeutic agent preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device
US9629799B2 (en) 2010-12-23 2017-04-25 Rani Therapeutics, Llc Therapeutic agent preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device
US8734429B2 (en) 2010-12-23 2014-05-27 Rani Therapeutics, Llc Device, system and methods for the oral delivery of therapeutic compounds
US8809271B2 (en) 2010-12-23 2014-08-19 Rani Therapeutics, Llc Therapeutic agent preparations comprising liraglutide for delivery into a lumen of the intestinal tract using a swallowable drug delivery device
IN2014CN00338A (da) 2011-06-29 2015-04-03 Rani Therapeutics Llc
EP2968071B1 (en) * 2013-03-15 2021-08-04 Rani Therapeutics, LLC Device for oral delivery of therapeutic compounds
US20160354509A1 (en) * 2014-02-10 2016-12-08 The Johns Hopkins University Devices for and methods of treatment of metabolic syndromes
US11548940B2 (en) 2014-05-15 2023-01-10 Rani Therapeutics, Llc Anti-interleukin antibody preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device
US9492396B2 (en) 2014-07-15 2016-11-15 Yossi Gross Enhanced drug delivery pill
JP7202070B2 (ja) 2015-05-01 2023-01-11 ラニ セラピューティクス, エルエルシー ポリペプチドおよび/またはタンパク質を含む固体塊の製作のための薬学的組成物および方法

Also Published As

Publication number Publication date
CA3109094A1 (en) 2020-02-20
ES2946594T3 (es) 2023-07-21
CN112867483B (zh) 2023-03-21
IL280777A (en) 2021-04-29
JP2021534145A (ja) 2021-12-09
EP3836906A1 (en) 2021-06-23
WO2020035857A1 (en) 2020-02-20
US20200297646A1 (en) 2020-09-24
EP3836906B1 (en) 2023-03-29
JP7344277B2 (ja) 2023-09-13
US20200054568A1 (en) 2020-02-20
US10675248B2 (en) 2020-06-09
US10980750B2 (en) 2021-04-20
AU2019323183A1 (en) 2021-04-08
CN112867483A (zh) 2021-05-28

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