DK3768825T3 - Biosensor til mandlig infertilitet - Google Patents

Biosensor til mandlig infertilitet Download PDF

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Publication number
DK3768825T3
DK3768825T3 DK19759542.4T DK19759542T DK3768825T3 DK 3768825 T3 DK3768825 T3 DK 3768825T3 DK 19759542 T DK19759542 T DK 19759542T DK 3768825 T3 DK3768825 T3 DK 3768825T3
Authority
DK
Denmark
Prior art keywords
biosensor
male infertility
infertility
male
Prior art date
Application number
DK19759542.4T
Other languages
Danish (da)
English (en)
Inventor
Mohamad Takwa
Kushagr Punyani
Sudha Srivastava
Original Assignee
Spermosens Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Spermosens Ab filed Critical Spermosens Ab
Application granted granted Critical
Publication of DK3768825T3 publication Critical patent/DK3768825T3/da

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Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5044Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0608Germ cells
    • C12N5/0612Germ cells sorting of gametes, e.g. according to sex or motility
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/28Electrolytic cell components
    • G01N27/30Electrodes, e.g. test electrodes; Half-cells
    • G01N27/327Biochemical electrodes, e.g. electrical or mechanical details for in vitro measurements
    • G01N27/3275Sensing specific biomolecules, e.g. nucleic acid strands, based on an electrode surface reaction
    • G01N27/3277Sensing specific biomolecules, e.g. nucleic acid strands, based on an electrode surface reaction being a redox reaction, e.g. detection by cyclic voltammetry
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54306Solid-phase reaction mechanisms
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366Apparatus specially adapted for solid-phase testing
    • G01N33/54373Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings
    • G01N33/5438Electrodes
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/689Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to pregnancy or the gonads

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Cell Biology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Gynecology & Obstetrics (AREA)
  • Toxicology (AREA)
  • Reproductive Health (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Electrochemistry (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Developmental Biology & Embryology (AREA)
  • General Engineering & Computer Science (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
DK19759542.4T 2018-08-24 2019-08-23 Biosensor til mandlig infertilitet DK3768825T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP18190720 2018-08-24
PCT/EP2019/072574 WO2020039064A1 (en) 2018-08-24 2019-08-23 Biosensor for male infertility

Publications (1)

Publication Number Publication Date
DK3768825T3 true DK3768825T3 (da) 2021-09-20

Family

ID=63405057

Family Applications (1)

Application Number Title Priority Date Filing Date
DK19759542.4T DK3768825T3 (da) 2018-08-24 2019-08-23 Biosensor til mandlig infertilitet

Country Status (16)

Country Link
US (3) US20210325370A1 (https=)
EP (1) EP3768825B1 (https=)
JP (1) JP7168265B2 (https=)
KR (1) KR102594453B1 (https=)
CN (1) CN112639078B (https=)
AU (1) AU2019325300B2 (https=)
BR (1) BR112021001488A2 (https=)
DK (1) DK3768825T3 (https=)
EA (1) EA202190166A1 (https=)
ES (1) ES2889973T3 (https=)
IL (1) IL280445B2 (https=)
MX (1) MX2021002145A (https=)
PL (1) PL3768825T3 (https=)
SG (1) SG11202100358VA (https=)
WO (1) WO2020039064A1 (https=)
ZA (1) ZA202100472B (https=)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20240003911A1 (en) * 2020-11-23 2024-01-04 The University Of Toledo Quantification of sperm centriole quality
EP4713691A1 (en) * 2023-05-16 2026-03-25 Technion Research & Development Foundation Limited Method of determining fusogenic potential of sperm and use thereof in assisted fertilization and drug screening
CN116773427A (zh) * 2023-07-25 2023-09-19 香港大学深圳医院 通过流式细胞术检测精子体外受精能力的方法
CN120741585B (zh) * 2025-08-28 2025-11-11 华中科技大学 一种精子质量检测传感器及其制备方法

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1056858B1 (en) 1998-02-19 2004-12-08 Eastern Virginia Medical School RECOMBINANT ACTIVE HUMAN ZONA PELLUCIDA PROTEIN 3 (hZP3)
US6649419B1 (en) * 2000-11-28 2003-11-18 Large Scale Proteomics Corp. Method and apparatus for protein manipulation
WO2003011118A2 (en) 2001-08-02 2003-02-13 Trinity Biomedical Technology Corporation Human zona pellucida proteins and methods of their use in diagnosing male infertility
WO2006108183A2 (en) * 2005-04-05 2006-10-12 Corning Incorporated Label free biosensors and cells
WO2008026906A1 (es) * 2006-08-25 2008-03-06 Instituto Nacional De Ciencias Médicas Y Nutrición Salvador Zubirán Ensayo de captura de espermatozoides utilizando las proteinas zp2, zp3 y zp4
EP2255204B1 (en) 2008-03-20 2013-11-06 Tidhar Zanbar Method and kit for diagnosis of male fertility
WO2013012749A2 (en) 2011-07-15 2013-01-24 The Curators Of The University Of Missouri Human zona pellucida glycoproteins, their oligosaccharides, and uses thereof
JP5954800B2 (ja) 2012-02-17 2016-07-20 国立研究開発法人産業技術総合研究所 男性不妊症の原因因子検出方法及び男性不妊症モデル動物
RU2487705C1 (ru) * 2012-03-21 2013-07-20 ОКТАПАМ Лимитед Средство для улучшения репродуктивной функции
SG11201603225YA (en) * 2013-11-04 2016-05-30 Agency Science Tech & Res Optical sensing device for surface plasmon resonance (spr) and optical sensing method using surface plasmon resonance (spr)
CN106033086B (zh) 2015-03-17 2018-03-09 中国科学院宁波材料技术与工程研究所 基于lspr检测精子顶体酶活性的方法、试剂盒及其应用
US20170219554A1 (en) * 2016-01-29 2017-08-03 Mara Nanotech New York, Inc. Apparatus and method for detecting analytes in solution
CN108152189B (zh) * 2017-12-06 2020-06-05 浙江大学 一种精子表面出云蛋白1的定量检测方法

Also Published As

Publication number Publication date
MX2021002145A (es) 2021-04-28
CN112639078B (zh) 2025-11-07
EP3768825A1 (en) 2021-01-27
CN112639078A (zh) 2021-04-09
US20220026413A1 (en) 2022-01-27
PL3768825T3 (pl) 2021-12-06
CA3109529A1 (en) 2020-02-27
KR20210049134A (ko) 2021-05-04
ZA202100472B (en) 2022-07-27
US20210325370A1 (en) 2021-10-21
EA202190166A1 (ru) 2021-05-28
BR112021001488A2 (pt) 2021-04-27
EP3768825B1 (en) 2021-08-11
AU2019325300A1 (en) 2021-04-15
JP7168265B2 (ja) 2022-11-09
IL280445A (en) 2021-03-01
IL280445B2 (en) 2025-11-01
ES2889973T3 (es) 2022-01-14
AU2019325300B2 (en) 2023-10-05
US20250306010A1 (en) 2025-10-02
KR102594453B1 (ko) 2023-10-25
SG11202100358VA (en) 2021-04-29
US11782052B2 (en) 2023-10-10
WO2020039064A1 (en) 2020-02-27
JP2021535366A (ja) 2021-12-16
IL280445B1 (en) 2025-07-01

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