DK369384A - 1,6-naphthyridinonderivater, fremgangsmaade til fremstilling heraf og deres anvendelse til bekaempelse af karsygdomme - Google Patents

1,6-naphthyridinonderivater, fremgangsmaade til fremstilling heraf og deres anvendelse til bekaempelse af karsygdomme Download PDF

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Publication number
DK369384A
DK369384A DK369384A DK369384A DK369384A DK 369384 A DK369384 A DK 369384A DK 369384 A DK369384 A DK 369384A DK 369384 A DK369384 A DK 369384A DK 369384 A DK369384 A DK 369384A
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DK
Denmark
Prior art keywords
general formula
group
alkyl
see diagramm
groups
Prior art date
Application number
DK369384A
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Danish (da)
English (en)
Other versions
DK369384D0 (da
Inventor
Gerhard Satzinger
Johannes Hartenstein
Karl Mannhardt
Juergen Kleinschroth
Manfred Herrmann
Edgar Fritschi
Bernd Wagner
Guenther Wolf
Horst-Dietmar Tauschel
Original Assignee
Goedecke Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Goedecke Ag filed Critical Goedecke Ag
Publication of DK369384D0 publication Critical patent/DK369384D0/da
Publication of DK369384A publication Critical patent/DK369384A/da

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
    • C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Saccharide Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK369384A 1983-07-30 1984-07-27 1,6-naphthyridinonderivater, fremgangsmaade til fremstilling heraf og deres anvendelse til bekaempelse af karsygdomme DK369384A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19833327650 DE3327650A1 (de) 1983-07-30 1983-07-30 1,6-naphthyridinon-derivate, verfahren zu deren herstellung und deren verwendung bei der bekaempfung von gefaesserkrankungen

Publications (2)

Publication Number Publication Date
DK369384D0 DK369384D0 (da) 1984-07-27
DK369384A true DK369384A (da) 1985-01-31

Family

ID=6205414

Family Applications (1)

Application Number Title Priority Date Filing Date
DK369384A DK369384A (da) 1983-07-30 1984-07-27 1,6-naphthyridinonderivater, fremgangsmaade til fremstilling heraf og deres anvendelse til bekaempelse af karsygdomme

Country Status (12)

Country Link
EP (1) EP0133530B1 (xx)
JP (1) JPS6054385A (xx)
AT (1) ATE41423T1 (xx)
AU (1) AU3129984A (xx)
DD (1) DD223151A5 (xx)
DE (2) DE3327650A1 (xx)
DK (1) DK369384A (xx)
ES (1) ES534685A0 (xx)
FI (1) FI843005A (xx)
GR (1) GR82225B (xx)
HU (1) HUT34485A (xx)
ZA (1) ZA845829B (xx)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3502831A1 (de) * 1985-01-29 1986-07-31 Gödecke AG, 1000 Berlin 1,6-naphthyridinon-derivate, verfahren zu deren herstellung und deren verwendung
US4698341A (en) * 1983-07-30 1987-10-06 Godecke Aktiengesellschaft Use of 1,6-naphthyridinone derivatives in treating pulmonary thrombosis
US4532247A (en) * 1983-08-08 1985-07-30 Sterling Drug Inc. 5-(Hydroxyalkyl or alkanoyloxymethyl)-1,6-naphthyridin-2(1H)-one and cardiotonic use thereof
DE3602655A1 (de) * 1985-01-29 1987-07-30 Goedecke Ag 1,6-naphthyridin-derivate, verfahren zu deren herstellung und deren verwendung
IL75987A (en) * 1984-08-25 1991-07-18 Goedecke Ag Tri-and tetrasubstituted-1,4-dihydro-1,6-naphthyridine-3-carboxylic acid derivatives,their preparation and pharmaceutical compositions containing them
DE3431303A1 (de) * 1984-08-25 1986-02-27 Goedecke Ag 1,6-naphthyridin-derivate, verfahren zu deren herstellung und deren verwendung
IT1201454B (it) * 1985-08-19 1989-02-02 Boehringer Biochemia Srl 1,4-diidropiridine-2-sostituite
DE3605742A1 (de) * 1986-02-22 1987-08-27 Goedecke Ag Pyrrolo(3,4-b)pyridine, verfahren zu deren herstellung und deren verwendung
IT1229118B (it) * 1988-07-29 1991-07-22 Simes Composti attivi sul sistema cardiovascolare che presentano sia la struttura dei beta-bloccanti sia una porzione calcio-antagonista
JPH0734202A (ja) * 1993-07-23 1995-02-03 Toshiba Corp 蒸気タービン用ロータ
US6499946B1 (en) 1999-10-21 2002-12-31 Kabushiki Kaisha Toshiba Steam turbine rotor and manufacturing method thereof
WO2002010164A2 (en) * 2000-08-02 2002-02-07 Abbott Laboratories Dihydronaphthyridine- and dihydropyrrolopyridine-derivated compounds as potassium channel openers
JP4509664B2 (ja) 2003-07-30 2010-07-21 株式会社東芝 蒸気タービン発電設備
DE102006026583A1 (de) 2006-06-07 2007-12-13 Bayer Healthcare Aktiengesellschaft Aryl-substituierte hetero-bicyclische Verbindungen und ihre Verwendung
DE102006026585A1 (de) 2006-06-07 2007-12-13 Bayer Healthcare Aktiengesellschaft Substituierte 4-Aryl-1,4-dihydro-1,6-naphthyridine und ihre Verwendung
DE102007009494A1 (de) 2007-02-27 2008-08-28 Bayer Healthcare Ag Substituierte 4-Aryl-1, 4-dihydro-1,6-naphthyridinamide und ihre Verwendung

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5553291A (en) * 1978-10-17 1980-04-18 Nippon Kayaku Co Ltd Naphthylidine derivative and its preparation
HU183174B (en) * 1980-06-26 1984-04-28 Chinoin Gyogyszer Es Vegyeszet Process for producing 1,6-naphtirine derivatives
US4304914A (en) * 1980-07-07 1981-12-08 Usv Pharmaceutical Corporation Naphthyridone derivatives
GB2093834B (en) * 1981-02-27 1984-08-15 American Home Prod Antihypertensive agents

Also Published As

Publication number Publication date
FI843005A (fi) 1985-01-31
GR82225B (xx) 1984-12-13
JPS6054385A (ja) 1985-03-28
ATE41423T1 (de) 1989-04-15
EP0133530A3 (en) 1987-12-23
ES8504800A1 (es) 1985-05-01
DE3327650A1 (de) 1985-02-14
EP0133530B1 (de) 1989-03-15
DK369384D0 (da) 1984-07-27
EP0133530A2 (de) 1985-02-27
JPS6346077B2 (xx) 1988-09-13
FI843005A0 (fi) 1984-07-27
ES534685A0 (es) 1985-05-01
DD223151A5 (de) 1985-06-05
AU3129984A (en) 1985-01-31
ZA845829B (en) 1985-03-27
DE3477195D1 (en) 1989-04-20
HUT34485A (en) 1985-03-28

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Legal Events

Date Code Title Description
AHB Application shelved due to non-payment