DK3682247T3 - Proadrenomedullin som markør for unormale blodpladeniveauer - Google Patents

Proadrenomedullin som markør for unormale blodpladeniveauer Download PDF

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Publication number
DK3682247T3
DK3682247T3 DK18765659.0T DK18765659T DK3682247T3 DK 3682247 T3 DK3682247 T3 DK 3682247T3 DK 18765659 T DK18765659 T DK 18765659T DK 3682247 T3 DK3682247 T3 DK 3682247T3
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DK
Denmark
Prior art keywords
proadrenomedullin
marker
abnormal blood
blood plate
plate levels
Prior art date
Application number
DK18765659.0T
Other languages
English (en)
Inventor
Aline Pehla
Stefan Kirsch
Darius Wilson
Original Assignee
Brahms Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Brahms Gmbh filed Critical Brahms Gmbh
Application granted granted Critical
Publication of DK3682247T3 publication Critical patent/DK3682247T3/da

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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/74Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/86Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood coagulating time or factors, or their receptors
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/22Haematology
    • G01N2800/222Platelet disorders
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/50Determining the risk of developing a disease
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/52Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
DK18765659.0T 2017-09-13 2018-09-13 Proadrenomedullin som markør for unormale blodpladeniveauer DK3682247T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP17190912 2017-09-13
EP18161091 2018-03-09
PCT/EP2018/074725 WO2019053118A1 (en) 2017-09-13 2018-09-13 PROADRÉNOMÉDULLINE AS A MARKER OF ABNORMAL PLATELET RATES

Publications (1)

Publication Number Publication Date
DK3682247T3 true DK3682247T3 (da) 2022-03-21

Family

ID=63517904

Family Applications (1)

Application Number Title Priority Date Filing Date
DK18765659.0T DK3682247T3 (da) 2017-09-13 2018-09-13 Proadrenomedullin som markør for unormale blodpladeniveauer

Country Status (8)

Country Link
US (3) US11327082B2 (da)
EP (3) EP3682247B1 (da)
JP (1) JP7346389B2 (da)
CN (1) CN111094987B (da)
DK (1) DK3682247T3 (da)
ES (1) ES2909399T3 (da)
PL (1) PL3682247T3 (da)
WO (1) WO2019053118A1 (da)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3141817A1 (en) * 2019-05-24 2020-12-03 Astute Medical, Inc. Methods for evaluation and treatment of renal injury based on c-c motif chemokine ligand 14 measurement

Family Cites Families (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2570703B1 (fr) 1984-09-26 1988-07-08 Commissariat Energie Atomique Complexes macropolycycliques de terres rares et application a titre de marqueurs fluorescents
US4882733A (en) 1987-03-13 1989-11-21 Ford Aerospace Corporation Method and apparatus for combining encoding and modulation
FR2664699B1 (fr) 1990-07-13 1995-08-18 Cis Bio Int Procede d'amplification du signal d'emission d'un compose luminescent.
JPH11512087A (ja) 1995-08-18 1999-10-19 アメリカ合衆国 ヒトの病理学及び生理学における、アドレノメジュリン(am)及び遺伝子関連産物(pamp)の機能的役割
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EP1453529A4 (en) * 2001-09-19 2007-09-26 Oklahoma Med Res Found TREATMENT OF SEPSIS WITH TAFI
DE10316583A1 (de) 2003-04-10 2004-10-28 B.R.A.H.M.S Aktiengesellschaft Bestimmung eines midregionalen Proadrenomedullin-Teilpeptids in biologischen Flüssigkeiten zu diagnostischen Zwecken, sowie Immunoassays für die Durchführung einer solchen Bestimmung
US20060029589A1 (en) * 2004-06-01 2006-02-09 Hartmut Weiler Induction of heterozygous FV Leiden carrier status to reduce mortality in sepsis and to prevent organ damage caused by inflammation and/or ischemia-reperfusion injury
CA2614507A1 (en) * 2004-07-09 2006-08-17 Amaox, Ltd. Immune cell biosensors and methods of using same
ES2300681T3 (es) * 2004-07-22 2008-06-16 Brahms Aktiengesellschaft Procedimiento para el diagnostico y tratamiento de pacientes criticos con endotelina, agonistas de endotelina y antagonistas de adrenomedulina.
DE102006034142A1 (de) 2006-07-24 2008-01-31 B.R.A.H.M.S. Aktiengesellschaft Verfahren zur Steuerung der Therapie von Patienten mit Herzinsuffizienz anhand der vitro Bestimmung von Schwellenwerten von vasoaktiven Peptiden
DE102006052916A1 (de) * 2006-11-08 2008-05-15 Brahms Aktiengesellschaft Diagnose und Risikostratifizierung von Diabetes mellitus mittels MR-proADM
DE102006060112A1 (de) 2006-12-20 2008-06-26 Brahms Aktiengesellschaft Diagnose und Risikostratifizierung mittels dem neuen Marker CT-proADM
EP2118665B1 (en) 2007-03-12 2012-04-18 Biomedica Medizinprodukte GmbH & Co KG Diagnosis of septic complications
PL2185937T5 (pl) 2007-09-07 2014-12-31 Univ Zuerich Sposób wykrywania posocznicy u ludzi
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ITPI20090066A1 (it) * 2009-05-26 2010-11-27 Consiglio Nazionale Ricerche Metodo per produrre un dispositivo applicabile a tessuti biologici, in particolare un patch per trattare tessuti danneggiati, e dispositivo ottenuto con tale metodo
ES2536761T3 (es) 2009-06-05 2015-05-28 B.R.A.H.M.S Gmbh Detección de infecciones bacterianas en individuos que padecen disnea
US8383332B2 (en) 2009-10-13 2013-02-26 B.R.A.H.M.S. Gmbh Procalcitonin for the diagnosis of bacterial infections and guidance of antibiotic treatment in patients with acute stroke or transient ischemic attack
RU2580278C2 (ru) 2010-03-08 2016-04-10 Б.Р.А.Х.М.С Гмбх Прокальцитонин для диагностики бактериальных инфекций и контроля лечения антибиотиками для пациентов с неспецифическими жалобами
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WO2013073545A1 (ja) * 2011-11-15 2013-05-23 旭化成ファーマ株式会社 敗血症の治療及び/又は改善のための医薬
US10935548B2 (en) 2011-12-08 2021-03-02 Astute Medical, Inc. Methods for diagnosis and prognosis of renal injury and renal failure using insulin-like growth factor-binding protein 7 and metalloproteinase inhibitor 2
EP2848936B1 (en) * 2012-05-07 2019-10-02 LSI Medience Corporation Method for detecting disseminated intravascular coagulation or infectious disseminated intravascular coagulation
CA2907467A1 (en) 2013-03-20 2014-09-25 Sphingotec Gmbh Adrenomedullin to guide therapy of blood pressure decline
WO2017089474A1 (en) 2015-11-27 2017-06-01 Brahms Gmbh MR-proADM AS MARKER FOR THE EXTRACELLULAR VOLUME STATUS OF A SUBJECT
EP3482208B1 (en) 2016-07-08 2023-04-12 SphingoTec GmbH Adrenomedullin for assessing congestion in a subject with acute heart failure
JP7104689B2 (ja) 2016-08-09 2022-07-21 ベー.エル.アー.ハー.エム.エス ゲゼルシャフト ミット ベシュレンクテル ハフツング 有害事象を示すマーカーとしてのヒストンおよび/またはproADM

Also Published As

Publication number Publication date
EP3682247B1 (en) 2022-02-09
JP2020533593A (ja) 2020-11-19
US20200271675A1 (en) 2020-08-27
EP3971572A1 (en) 2022-03-23
US20220229076A1 (en) 2022-07-21
CN111094987A (zh) 2020-05-01
PL3682247T3 (pl) 2022-04-25
CN111094987B (zh) 2023-10-31
EP3682247A1 (en) 2020-07-22
ES2909399T3 (es) 2022-05-06
WO2019053118A1 (en) 2019-03-21
JP7346389B2 (ja) 2023-09-19
EP3971573A1 (en) 2022-03-23
US11327082B2 (en) 2022-05-10
US20220221474A1 (en) 2022-07-14

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