DK367683A - Fremgangsmaade til fremstilling af n-substituerede 1-oxido-nicotinamider og salte deraf - Google Patents

Fremgangsmaade til fremstilling af n-substituerede 1-oxido-nicotinamider og salte deraf Download PDF

Info

Publication number
DK367683A
DK367683A DK367683A DK367683A DK367683A DK 367683 A DK367683 A DK 367683A DK 367683 A DK367683 A DK 367683A DK 367683 A DK367683 A DK 367683A DK 367683 A DK367683 A DK 367683A
Authority
DK
Denmark
Prior art keywords
nicotinamides
oxido
salts
substituted
procedure
Prior art date
Application number
DK367683A
Other languages
Danish (da)
English (en)
Other versions
DK367683D0 (da
Inventor
Dino Nisato
Sergio Boveri
Original Assignee
Sanofi Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR8214128A external-priority patent/FR2531704B1/fr
Priority claimed from FR8306681A external-priority patent/FR2544717B1/fr
Application filed by Sanofi Sa filed Critical Sanofi Sa
Publication of DK367683D0 publication Critical patent/DK367683D0/da
Publication of DK367683A publication Critical patent/DK367683A/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62—Oxygen or sulfur atoms
    • C07D213/63—One oxygen atom
    • C07D213/64—One oxygen atom attached in position 2 or 6
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/20—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms
    • C07D211/22—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms by oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/40—Oxygen atoms
    • C07D211/44—Oxygen atoms attached in position 4
    • C07D211/46—Oxygen atoms attached in position 4 having a hydrogen atom as the second substituent in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/81—Amides; Imides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/81—Amides; Imides
    • C07D213/82—Amides; Imides in position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/89—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members with hetero atoms directly attached to the ring nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/096—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyridine Compounds (AREA)
DK367683A 1982-08-13 1983-08-12 Fremgangsmaade til fremstilling af n-substituerede 1-oxido-nicotinamider og salte deraf DK367683A (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR8214128A FR2531704B1 (fr) 1982-08-13 1982-08-13 Amides d'acides (hetero)aromatiques n-substitues, leurs sels, procede pour leur preparation et compositions pharmaceutiques en contenant
FR8306681A FR2544717B1 (fr) 1983-04-22 1983-04-22 Nicotinamide l-oxyde n-substitue, ses sels, procede pour leur preparation et compositions pharmaceutiques en contenant

Publications (2)

Publication Number Publication Date
DK367683D0 DK367683D0 (da) 1983-08-12
DK367683A true DK367683A (da) 1984-02-14

Family

ID=26223047

Family Applications (1)

Application Number Title Priority Date Filing Date
DK367683A DK367683A (da) 1982-08-13 1983-08-12 Fremgangsmaade til fremstilling af n-substituerede 1-oxido-nicotinamider og salte deraf

Country Status (20)

Country Link
US (1) US4514408A (pl)
EP (1) EP0101380A3 (pl)
AU (1) AU556247B2 (pl)
CA (1) CA1209995A (pl)
CS (1) CS241064B2 (pl)
DD (1) DD213921A5 (pl)
DK (1) DK367683A (pl)
FI (1) FI832919A (pl)
GR (1) GR78927B (pl)
HU (1) HU191869B (pl)
IL (1) IL69392A (pl)
MA (1) MA19871A1 (pl)
NO (1) NO832894L (pl)
NZ (1) NZ205239A (pl)
OA (1) OA07521A (pl)
PH (1) PH19511A (pl)
PL (1) PL141540B1 (pl)
PT (1) PT77192B (pl)
SU (1) SU1212323A3 (pl)
YU (1) YU169083A (pl)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4764598A (en) * 1985-08-22 1988-08-16 The United States Of America As Represented By The Department Of Energy Precursors to radiopharmaceutical agents for tissue imaging
MA20552A1 (fr) * 1985-10-11 1986-07-01 Pan Medica Sa Alkylacarboxamides de pyridylalkylamines,leurs preparations et leurs utilisations
US4994456A (en) * 1989-03-01 1991-02-19 Nisshin Flour Milling Co., Ltd. Pyridinecarboxylic acid amide derivatives and pharmaceutical compositions comprising same
EP0569587A1 (en) * 1991-01-30 1993-11-18 Central Glass Company, Limited Phthalimide compound and production thereof
DE69209576D1 (de) * 1991-05-10 1996-05-09 Takeda Chemical Industries Ltd Pyridinderivate, deren Herstellung und Anwendung
CN101184753A (zh) * 2005-05-31 2008-05-21 阿斯利康(瑞典)有限公司 新颖的mchr1拮抗剂以及它们用于治疗mchr1介导的病症和疾病的用途
EP4196793A1 (en) 2020-08-11 2023-06-21 Université de Strasbourg H2 blockers targeting liver macrophages for the prevention and treatment of liver disease and cancer
CN114523832B (zh) * 2020-11-19 2023-12-22 本田技研工业(中国)投资有限公司 一种电池保护装置、车辆及电池保护装置的安装方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL131190C (pl) * 1961-12-06
JPS568352A (en) * 1979-07-03 1981-01-28 Shionogi & Co Ltd Aminoalkylvenzene derivative
US4293557A (en) * 1979-07-03 1981-10-06 Teikoku Hormone Mfg. Co., Ltd. Antiulcer phenoxypropylamine derivatives

Also Published As

Publication number Publication date
IL69392A (en) 1987-01-30
DK367683D0 (da) 1983-08-12
GR78927B (pl) 1984-10-02
AU556247B2 (en) 1986-10-30
CS587683A2 (en) 1985-07-16
EP0101380A3 (fr) 1985-10-16
NO832894L (no) 1984-02-14
PL243410A1 (en) 1985-05-07
YU169083A (en) 1986-12-31
SU1212323A3 (ru) 1986-02-15
PT77192A (fr) 1983-09-01
OA07521A (fr) 1985-03-31
PL141540B1 (en) 1987-08-31
CA1209995A (fr) 1986-08-19
FI832919A (fi) 1984-02-14
IL69392A0 (en) 1983-11-30
HU191869B (en) 1987-04-28
MA19871A1 (fr) 1984-04-01
DD213921A5 (de) 1984-09-26
US4514408A (en) 1985-04-30
PH19511A (en) 1986-05-14
EP0101380A2 (fr) 1984-02-22
PT77192B (fr) 1986-02-03
CS241064B2 (en) 1986-03-13
AU1780783A (en) 1984-02-16
NZ205239A (en) 1985-09-13
FI832919A0 (fi) 1983-08-12

Similar Documents

Publication Publication Date Title
DK438983D0 (da) Fremgangsmade til fremstilling af n-substituerede benzimidazoler
DK157301C (da) Analogifremgangsmaade til fremstilling af hydantoinderivater og salte deraf
DK513883D0 (da) Fremgangsmade til fremstilling af aminderivater
DK533484D0 (da) Biologisk virksomme peptider og salte, estere og amider deraf samt fremgangsmaade til fremstilling af saadanne forbindelser
DK164543C (da) Salte af l-carnitin og alkanoyl-l-carnitiner, fremgangsmaade til deres fremstilling og farmaceutiske kompositioner indeholdende forbindelserne
DK531479A (da) Fremgangsmaade til fremstilling af imidazolderivater og salte deraf
DK164917C (da) Analogifremgangsmaade til fremstilling af bicyklisk substituerede dipeptidderivater og deres farmaceutisk acceptable salte
DK397387A (da) Carbostyrilderivater og salte deraf samt fremgangsmaade til fremstilling af saadanne forbindelser
DK8386A (da) Nye n-substituerede 1-benzyl-2-carbamoyltetrahydroisoquinoliner og fremgangsmaade til fremstilling af samme
DK32383D0 (da) Phosphinsyrederivater og fremgangsmade til fremstilling af disse
DK437480A (da) Fremgangsmaade til fremstilling af benzodiazepinderivater og salte deraf
DK209383A (da) Fremgangsmaade til fremstilling af aziridin- og phenylethanolaminderivater
DK498683A (da) Fremgangsmaade til fremstilling af n-substituerede flavon-8-carboxamider
DK163989C (da) Analogifremgangsmaade til fremstilling af beta-adrenergisk blokerende forbindelser og farmaceutisk acceptable salte deraf
DK163427C (da) Saerlig fremgangsmaade til fremstilling af alfa-arylalkansyrer og salte heraf ved omlejring af alfa-halogenalkylarylketaler
DK16883D0 (da) Fremgangsmade til fremstilling af n-substituerede aminobenzamider
DK367683A (da) Fremgangsmaade til fremstilling af n-substituerede 1-oxido-nicotinamider og salte deraf
DK537687A (da) Fremgangsmaade til fremstilling af n-substituerede piperazinoner
DK85183D0 (da) Fremgangsmade til fremstilling af benzokondenserede tricycliske forbindelser eller farmaceutisk acceptable salte deraf og mellemprodukter derved
DK162230C (da) Fremgangsmaade til fremstilling af 2-thiacephemderivater
DK214681A (da) Fremgangsmaade til fremstilling af pyrazinyl1,2,4-oxadiazoler og kvaternaere salte deraf
DK316178A (da) Fremgangsmaade til fremstilling af benzopyranderivater isaer 3-oxaloamino-4-oxo4h-1-benzopyranderivater og salte deraf
DK333279A (da) Fremgangsmaade til fremstilling af thiosubstitituerede diazacycloalkener og salte deraf
DK423284A (da) Naphthalenylimidazopyridin og derivater heraf samt fremgangsmaade til fremstilling af saadanne forbindelser
DK228582A (da) Fremgangsmaade til fremstilling af n-(aryloxyalkyl)-n!-(aminoalkyl)-urinstoffer og thiourinstoffer

Legal Events

Date Code Title Description
AHB Application shelved due to non-payment