DK3632912T3 - Pyridoquinazolin-derivater, der er anvendelige som proteinkinaseinhibitorer - Google Patents

Pyridoquinazolin-derivater, der er anvendelige som proteinkinaseinhibitorer Download PDF

Info

Publication number
DK3632912T3
DK3632912T3 DK18759146.6T DK18759146T DK3632912T3 DK 3632912 T3 DK3632912 T3 DK 3632912T3 DK 18759146 T DK18759146 T DK 18759146T DK 3632912 T3 DK3632912 T3 DK 3632912T3
Authority
DK
Denmark
Prior art keywords
pyridoquinazoline
protein kinase
kinase inhibitors
derivatives useful
derivatives
Prior art date
Application number
DK18759146.6T
Other languages
Danish (da)
English (en)
Inventor
Gómez Juan Camacho
Guido Kurz
Original Assignee
Oncostellae S L
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Oncostellae S L filed Critical Oncostellae S L
Application granted granted Critical
Publication of DK3632912T3 publication Critical patent/DK3632912T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/06Antipsoriatics
    • FMECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F24HEATING; RANGES; VENTILATING
    • F24CDOMESTIC STOVES OR RANGES ; DETAILS OF DOMESTIC STOVES OR RANGES, OF GENERAL APPLICATION
    • F24C7/00Stoves or ranges heated by electric energy
    • F24C7/08Arrangement or mounting of control or safety devices
    • F24C7/082Arrangement or mounting of control or safety devices on ranges, e.g. control panels, illumination
    • FMECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F24HEATING; RANGES; VENTILATING
    • F24CDOMESTIC STOVES OR RANGES ; DETAILS OF DOMESTIC STOVES OR RANGES, OF GENERAL APPLICATION
    • F24C7/00Stoves or ranges heated by electric energy
    • F24C7/08Arrangement or mounting of control or safety devices
    • F24C7/087Arrangement or mounting of control or safety devices of electric circuits regulating heat
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Dermatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Combustion & Propulsion (AREA)
  • Mechanical Engineering (AREA)
  • General Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DK18759146.6T 2017-06-01 2018-05-31 Pyridoquinazolin-derivater, der er anvendelige som proteinkinaseinhibitorer DK3632912T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ES201730759 2017-06-01
PCT/ES2018/070396 WO2018220252A1 (es) 2017-06-01 2018-05-31 Derivados de piridoquinazolina eficaces como inhibidores de proteína quinasa

Publications (1)

Publication Number Publication Date
DK3632912T3 true DK3632912T3 (da) 2021-05-10

Family

ID=61569288

Family Applications (1)

Application Number Title Priority Date Filing Date
DK18759146.6T DK3632912T3 (da) 2017-06-01 2018-05-31 Pyridoquinazolin-derivater, der er anvendelige som proteinkinaseinhibitorer

Country Status (22)

Country Link
US (1) US11021479B2 (https=)
EP (1) EP3632912B1 (https=)
JP (1) JP7110335B2 (https=)
KR (1) KR102629854B1 (https=)
CN (1) CN111247143B (https=)
AU (1) AU2018278283B2 (https=)
CA (1) CA3066009A1 (https=)
CY (1) CY1124087T1 (https=)
DK (1) DK3632912T3 (https=)
EA (1) EA037384B1 (https=)
ES (1) ES2881960T3 (https=)
HR (1) HRP20210814T1 (https=)
HU (1) HUE054792T2 (https=)
LT (1) LT3632912T (https=)
MX (1) MX385475B (https=)
PL (1) PL3632912T3 (https=)
PT (1) PT3632912T (https=)
RS (1) RS61833B1 (https=)
SI (1) SI3632912T1 (https=)
SM (1) SMT202100312T1 (https=)
WO (1) WO2018220252A1 (https=)
ZA (1) ZA201908372B (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HUE072013T2 (hu) 2020-01-31 2025-10-28 Lg Energy Solution Ltd Eljárás szervetlen többréteges szerkezetû szeparátor-kompozit elektróda elõállítására, és az azzal elõállított szeparátor-kompozit elektróda

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4551460A (en) 1982-05-10 1985-11-05 Hoffmann-La Roche Inc. Pyrido[2,1-b]quinazoline derivatives useful as agents for treatment of allergic conditions and vascular disorders involving thrombosis
WO1998023617A1 (en) * 1996-11-26 1998-06-04 American Cyanamid Company Hetero-biaryl-pyridoquinazolinone derivatives as anti-cancer agents
EP1684762A4 (en) * 2003-11-13 2009-06-17 Ambit Biosciences Corp UREA DERIVATIVES AS MODULATORS OF KINASE
WO2009086303A2 (en) * 2007-12-21 2009-07-09 University Of Rochester Method for altering the lifespan of eukaryotic organisms
WO2010061971A1 (ja) 2008-11-28 2010-06-03 興和株式会社 ピリジン-3-カルボキシアミド誘導体
EP3778600A1 (en) * 2014-03-20 2021-02-17 The Johns Hopkins University Compounds which inhibit rna polymerase, compositions including such compounds, and their use

Also Published As

Publication number Publication date
KR20200011990A (ko) 2020-02-04
SI3632912T1 (sl) 2021-08-31
CN111247143B (zh) 2022-07-05
US20200148676A1 (en) 2020-05-14
JP2020521817A (ja) 2020-07-27
AU2018278283B2 (en) 2021-06-17
JP7110335B2 (ja) 2022-08-01
KR102629854B1 (ko) 2024-01-25
EP3632912B1 (en) 2021-03-17
MX2019014436A (es) 2020-02-10
SMT202100312T1 (it) 2021-07-12
PT3632912T (pt) 2021-06-02
CA3066009A1 (en) 2018-12-06
PL3632912T3 (pl) 2021-09-06
AU2018278283A1 (en) 2019-12-19
ES2881960T3 (es) 2021-11-30
LT3632912T (lt) 2021-06-10
US11021479B2 (en) 2021-06-01
RS61833B1 (sr) 2021-06-30
CN111247143A (zh) 2020-06-05
HUE054792T2 (hu) 2021-09-28
MX385475B (es) 2025-03-18
EP3632912A1 (en) 2020-04-08
EA201992793A1 (ru) 2020-03-26
CY1124087T1 (el) 2022-05-27
BR112019024892A2 (pt) 2020-06-16
HRP20210814T1 (hr) 2021-06-25
EA037384B1 (ru) 2021-03-23
WO2018220252A1 (es) 2018-12-06
ZA201908372B (en) 2021-04-28

Similar Documents

Publication Publication Date Title
DK3784664T3 (da) 2-amino-pyridin- eller 2-amino-pyrimidinderivater som cyclinafhængige kinasehæmmere
LT3580220T (lt) Aminotriazolopiridinai, kaip kinazės inhibitoriai
DK3768674T3 (da) Aminopyrimidinderivater som ctps1-hæmmere
DK3704120T3 (da) Heterocykliske forbindelser som prmt5-inhibitorer
DK3684767T3 (da) Heterocykliske forbindelser som pad-inhibitorer
DK3656769T3 (da) Aryl-phosphor-oxygen-forbindelse som egfr-kinase-inhibitor
DK3442980T3 (da) Heterocykliske forbindelser som ret-kinase-hæmmere
LT3464272T (lt) Nauji heterocikliniai dariniai, naudingi kaip shp2 inhibitoriai
DK3298002T3 (da) Heterocykliske amider som kinasehæmmere
DK3609898T3 (da) Forbindelser, der er nyttige som ret-hæmmere
DK3582780T3 (da) Aminopyrimidinforbindelser, der er anvendelige som SSAO-inhibitorer
DK3302448T3 (da) Erstattede heterocyclylafledninger som cdk-inhibitore
DK3464271T3 (da) Pyrazolderivater som plasma-kallikreininhibitorer
DK3356345T3 (da) Heteroaryl-derivater som sepiapterin-reduktase-inhibitorer
DK3324977T3 (da) Benzodiazepinderivater som rsv-inhibitorer
DK3371190T3 (da) Heterocykliske forbindelser som pi3k-gamma-inhibitorer
DK3390395T3 (da) Forbindelser, der kan anvendes som kinase-inhibitorer
DK3365334T3 (da) Benzolactamforbindelser som proteinkinaseinhibitorer
DK3313832T3 (da) 3-tetrazolyl-benzen-1,2-disulfonamidderivater som metallo-beta- lactamase-hæmmere
DK3442535T3 (da) Heterocykliske stoffer som as ret-kinase-hæmmere
DK3870574T3 (da) Aminopyridin/pyrazinderivater som ctps1-inhibitorer
LT3704118T (lt) Aminoimidazopiridazinai, kaip kinazės inhibitoriai
DK3472165T3 (da) N-(substituererede-phenyl)-sulfonamidderivater som kinasehæmmere
DK3271349T3 (da) Benzimidazolederivater som bromodomain-inhibitorer
DK3638680T3 (da) Heteroaromatiske forbindelser som vanininhibitorer