DK3522905T3 - Immunogene arginasepeptider - Google Patents

Immunogene arginasepeptider Download PDF

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Publication number
DK3522905T3
DK3522905T3 DK17786870.0T DK17786870T DK3522905T3 DK 3522905 T3 DK3522905 T3 DK 3522905T3 DK 17786870 T DK17786870 T DK 17786870T DK 3522905 T3 DK3522905 T3 DK 3522905T3
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DK
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Prior art keywords
peptides
arginase
immunogenic
immunogenic arginase
arginase peptides
Prior art date
Application number
DK17786870.0T
Other languages
Danish (da)
English (en)
Inventor
Mads Hald Andersen
Original Assignee
Io Biotech Aps
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Io Biotech Aps filed Critical Io Biotech Aps
Application granted granted Critical
Publication of DK3522905T3 publication Critical patent/DK3522905T3/da

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/0005Vertebrate antigens
    • A61K39/0011Cancer antigens
    • A61K39/001154Enzymes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/78Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/96Stabilising an enzyme by forming an adduct or a composition; Forming enzyme conjugates
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y305/00Hydrolases acting on carbon-nitrogen bonds, other than peptide bonds (3.5)
    • C12Y305/03Hydrolases acting on carbon-nitrogen bonds, other than peptide bonds (3.5) in linear amidines (3.5.3)
    • C12Y305/03001Arginase (3.5.3.1)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Mycology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DK17786870.0T 2016-10-07 2017-10-06 Immunogene arginasepeptider DK3522905T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP16192794 2016-10-07
PCT/EP2017/075443 WO2018065563A1 (en) 2016-10-07 2017-10-06 Immunogenic arginase peptides

Publications (1)

Publication Number Publication Date
DK3522905T3 true DK3522905T3 (da) 2024-10-21

Family

ID=57123856

Family Applications (1)

Application Number Title Priority Date Filing Date
DK17786870.0T DK3522905T3 (da) 2016-10-07 2017-10-06 Immunogene arginasepeptider

Country Status (19)

Country Link
US (3) US10858642B2 (enExample)
EP (2) EP3522905B1 (enExample)
JP (1) JP7211938B2 (enExample)
KR (1) KR102674521B1 (enExample)
CN (1) CN109890399A (enExample)
AU (1) AU2017341112B2 (enExample)
CA (1) CA3039510A1 (enExample)
DK (1) DK3522905T3 (enExample)
ES (1) ES2992031T3 (enExample)
FI (1) FI3522905T3 (enExample)
HR (1) HRP20241486T1 (enExample)
HU (1) HUE069077T2 (enExample)
IL (1) IL265805B2 (enExample)
LT (1) LT3522905T (enExample)
MX (1) MX2019003970A (enExample)
PL (1) PL3522905T3 (enExample)
PT (1) PT3522905T (enExample)
SI (1) SI3522905T1 (enExample)
WO (1) WO2018065563A1 (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2018065563A1 (en) 2016-10-07 2018-04-12 Herlev Hospital Immunogenic arginase peptides
GB201815549D0 (en) * 2018-09-24 2018-11-07 Io Biotech Aps Arginase1 polypeptides
GB201818576D0 (en) * 2018-11-14 2018-12-26 Io Biotech Aps Arginase 2 polypeptides
GB201912030D0 (en) * 2019-08-21 2019-10-02 Cancer Research Tech Ltd Binding molecules
US20250327041A1 (en) 2022-02-24 2025-10-23 Io Biotech Aps Nucleotide delivery of cancer therapy
AU2023223567A1 (en) 2022-02-24 2024-08-15 Io Biotech Aps Arginase 2 vaccine

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US58767A (en) 1866-10-16 John brougjbton
US5554372A (en) 1986-09-22 1996-09-10 Emory University Methods and vaccines comprising surface-active copolymers
US5780286A (en) * 1996-03-14 1998-07-14 Smithkline Beecham Corporation Arginase II
US20110111424A1 (en) 2001-06-21 2011-05-12 Cell Signaling Technology, Inc. Analysis of ubiquitinated polypeptides
WO2003038444A2 (en) 2001-10-31 2003-05-08 Pfizer Products Inc. Biomarkers of liver function
WO2006050313A2 (en) * 2004-10-29 2006-05-11 The Board Of Trustees Operating Michigan State University Protection against herbivores
CA2742497C (en) 2008-10-31 2024-01-23 George Georgiou Compositions of engineered human arginases and methods for treating cancer
US8679479B2 (en) * 2009-06-29 2014-03-25 Aerase, Inc. Methods for purifying pegylated arginase
EP3137103B1 (en) * 2014-04-29 2021-10-20 Bio-Cancer Treatment International Ltd. Methods and compositions for modulating the immune system with arginase i
GB201501017D0 (en) * 2014-12-23 2015-03-04 Immatics Biotechnologies Gmbh Novel peptides and combination of peptides for use in immunotherapy against hepatocellular carcinoma (HCC) and other cancers
WO2018065563A1 (en) 2016-10-07 2018-04-12 Herlev Hospital Immunogenic arginase peptides
EP3532487A1 (en) * 2016-10-27 2019-09-04 IO Biotech APS New pdl2 compounds

Also Published As

Publication number Publication date
JP2019537562A (ja) 2019-12-26
CN109890399A (zh) 2019-06-14
US10858642B2 (en) 2020-12-08
AU2017341112A1 (en) 2019-05-02
AU2017341112B2 (en) 2024-06-27
US11981944B2 (en) 2024-05-14
JP7211938B2 (ja) 2023-01-24
FI3522905T3 (fi) 2024-10-31
PL3522905T3 (pl) 2025-01-07
EP3522905B1 (en) 2024-09-25
IL265805A (en) 2019-06-30
ES2992031T3 (es) 2024-12-05
US20210139877A1 (en) 2021-05-13
EP4406613A2 (en) 2024-07-31
EP3522905A1 (en) 2019-08-14
SI3522905T1 (sl) 2025-02-28
HRP20241486T1 (hr) 2025-01-03
IL265805B1 (en) 2024-04-01
US20190338270A1 (en) 2019-11-07
US20240167013A1 (en) 2024-05-23
LT3522905T (lt) 2024-11-11
WO2018065563A1 (en) 2018-04-12
HUE069077T2 (hu) 2025-02-28
CA3039510A1 (en) 2018-04-12
EP4406613A3 (en) 2024-10-23
IL265805B2 (en) 2024-08-01
KR20190077381A (ko) 2019-07-03
KR102674521B1 (ko) 2024-06-11
MX2019003970A (es) 2019-12-05
PT3522905T (pt) 2024-10-02

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