DK3521312T3 - Forbindelse, der binder specifikt til kir3dl2, til anvendelse til behandling af perifert t-cellelymfom - Google Patents
Forbindelse, der binder specifikt til kir3dl2, til anvendelse til behandling af perifert t-cellelymfom Download PDFInfo
- Publication number
- DK3521312T3 DK3521312T3 DK19163475.7T DK19163475T DK3521312T3 DK 3521312 T3 DK3521312 T3 DK 3521312T3 DK 19163475 T DK19163475 T DK 19163475T DK 3521312 T3 DK3521312 T3 DK 3521312T3
- Authority
- DK
- Denmark
- Prior art keywords
- periff
- kir3dl2
- treatment
- binding specifically
- compound binding
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
- C07K16/3023—Lung
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
- C07K16/3061—Blood cells
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57407—Specifically defined cancers
- G01N33/57426—Specifically defined cancers leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/33—Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
- C07K2317/732—Antibody-dependent cellular cytotoxicity [ADCC]
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
- G01N2333/70503—Immunoglobulin superfamily, e.g. VCAMs, PECAM, LFA-3
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Cell Biology (AREA)
- Biochemistry (AREA)
- Hematology (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- Urology & Nephrology (AREA)
- Biomedical Technology (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pathology (AREA)
- Hospice & Palliative Care (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Oncology (AREA)
- Food Science & Technology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201361766798P | 2013-02-20 | 2013-02-20 | |
US201361831809P | 2013-06-06 | 2013-06-06 | |
EP14706017.2A EP2958941B1 (en) | 2013-02-20 | 2014-02-20 | A compound that specifically binds to kir3dl2 for use in the treatment of peripheral t cell lymphoma |
Publications (1)
Publication Number | Publication Date |
---|---|
DK3521312T3 true DK3521312T3 (da) | 2021-06-28 |
Family
ID=50156759
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK14706017.2T DK2958941T3 (da) | 2013-02-20 | 2014-02-20 | Forbindelse, der binder specifikt til kir3dl2, til anvendelse til behandling af perifert t-cellelymfom |
DK19163475.7T DK3521312T3 (da) | 2013-02-20 | 2014-02-20 | Forbindelse, der binder specifikt til kir3dl2, til anvendelse til behandling af perifert t-cellelymfom |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK14706017.2T DK2958941T3 (da) | 2013-02-20 | 2014-02-20 | Forbindelse, der binder specifikt til kir3dl2, til anvendelse til behandling af perifert t-cellelymfom |
Country Status (9)
Country | Link |
---|---|
US (4) | US20160002345A1 (da) |
EP (3) | EP3521312B1 (da) |
JP (1) | JP6360077B2 (da) |
CN (1) | CN105026427B (da) |
AU (1) | AU2014220668B2 (da) |
CA (1) | CA2899241C (da) |
DK (2) | DK2958941T3 (da) |
ES (2) | ES2730011T3 (da) |
WO (1) | WO2014128221A1 (da) |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
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US9738724B2 (en) | 2012-06-08 | 2017-08-22 | Sutro Biopharma, Inc. | Antibodies comprising site-specific non-natural amino acid residues, methods of their preparation and methods of their use |
JP6507097B2 (ja) | 2012-09-19 | 2019-04-24 | イナート・ファルマ・ソシエテ・アノニムInnate Pharma Pharma S.A. | Kir3dl2結合剤 |
DK2958941T3 (da) | 2013-02-20 | 2019-06-24 | Innate Pharma | Forbindelse, der binder specifikt til kir3dl2, til anvendelse til behandling af perifert t-cellelymfom |
US20160130346A1 (en) * | 2013-05-29 | 2016-05-12 | Institut National De La Sante Et De La Recherche Medicale | Kir3dl2 is a biomarker and a therapeutic target useful for respectively preventing and treating a subset of cutaneous and non-cutaneous peripheral t-cell lymphomas |
EP3019522B1 (en) | 2013-07-10 | 2017-12-13 | Sutro Biopharma, Inc. | Antibodies comprising multiple site-specific non-natural amino acid residues, methods of their preparation and methods of their use |
SG11201606789SA (en) * | 2014-03-14 | 2016-09-29 | Innate Pharma | Humanized antibodies with increased stability |
WO2016030488A1 (en) * | 2014-08-27 | 2016-03-03 | Innate Pharma | Treatment of celiac disease |
EP3307784B1 (en) * | 2015-06-10 | 2021-12-22 | National Research Council of Canada | Carbonic anhydrase ix-specific antibodies and uses thereof |
KR102554507B1 (ko) | 2015-07-24 | 2023-07-11 | 이나뜨 파르마 에스.에이. | 조직 침윤성 nk 세포를 검출하는 방법 |
CN109069664B (zh) | 2016-01-27 | 2022-05-13 | 苏特罗生物制药公司 | 抗cd74抗体偶联物,包含抗cd74抗体偶联物的组合物以及抗cd74抗体偶联物的使用方法 |
KR20190008962A (ko) * | 2016-06-02 | 2019-01-25 | 브리스톨-마이어스 스큅 컴퍼니 | 림프종 치료에서의 항-cd30 항체와 조합된 항-pd-1 항체의 용도 |
JP2020500161A (ja) * | 2016-10-21 | 2020-01-09 | イナート・ファルマ・ソシエテ・アノニムInnate Pharma Pharma S.A. | 抗kir3dl2剤による処置 |
EP3658588A1 (en) * | 2017-07-26 | 2020-06-03 | Sutro Biopharma, Inc. | Methods of using anti-cd74 antibodies and antibody conjugates in treatment of t-cell lymphoma |
CN108319816B (zh) * | 2018-02-27 | 2021-04-23 | 广州大学 | 一种基于基因通路识别小分子核糖核酸的方法 |
WO2020152081A1 (en) | 2019-01-22 | 2020-07-30 | Innate Pharma | Treatment of t cell lymphoma |
AU2022255908A1 (en) * | 2021-04-05 | 2023-10-05 | Innate Pharma | Immunohistochemistry methods and kir3dl2-specific reagents |
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US10246510B2 (en) * | 2012-09-19 | 2019-04-02 | Innate Pharma | KIR3DL2 binding agents |
JP6507097B2 (ja) | 2012-09-19 | 2019-04-24 | イナート・ファルマ・ソシエテ・アノニムInnate Pharma Pharma S.A. | Kir3dl2結合剤 |
DK2958941T3 (da) | 2013-02-20 | 2019-06-24 | Innate Pharma | Forbindelse, der binder specifikt til kir3dl2, til anvendelse til behandling af perifert t-cellelymfom |
US20160130346A1 (en) | 2013-05-29 | 2016-05-12 | Institut National De La Sante Et De La Recherche Medicale | Kir3dl2 is a biomarker and a therapeutic target useful for respectively preventing and treating a subset of cutaneous and non-cutaneous peripheral t-cell lymphomas |
SG11201606789SA (en) | 2014-03-14 | 2016-09-29 | Innate Pharma | Humanized antibodies with increased stability |
JP2020500161A (ja) | 2016-10-21 | 2020-01-09 | イナート・ファルマ・ソシエテ・アノニムInnate Pharma Pharma S.A. | 抗kir3dl2剤による処置 |
-
2014
- 2014-02-20 DK DK14706017.2T patent/DK2958941T3/da active
- 2014-02-20 ES ES14706017T patent/ES2730011T3/es active Active
- 2014-02-20 CA CA2899241A patent/CA2899241C/en active Active
- 2014-02-20 JP JP2015557484A patent/JP6360077B2/ja active Active
- 2014-02-20 EP EP19163475.7A patent/EP3521312B1/en active Active
- 2014-02-20 DK DK19163475.7T patent/DK3521312T3/da active
- 2014-02-20 AU AU2014220668A patent/AU2014220668B2/en active Active
- 2014-02-20 WO PCT/EP2014/053340 patent/WO2014128221A1/en active Application Filing
- 2014-02-20 EP EP21166926.2A patent/EP3896088A1/en active Pending
- 2014-02-20 US US14/769,158 patent/US20160002345A1/en not_active Abandoned
- 2014-02-20 ES ES19163475T patent/ES2878749T3/es active Active
- 2014-02-20 CN CN201480009772.XA patent/CN105026427B/zh active Active
- 2014-02-20 EP EP14706017.2A patent/EP2958941B1/en active Active
-
2017
- 2017-06-15 US US15/623,572 patent/US10174112B2/en active Active
-
2019
- 2019-01-07 US US16/240,906 patent/US11078275B2/en active Active
-
2021
- 2021-07-29 US US17/388,052 patent/US20210363248A1/en active Pending
Also Published As
Publication number | Publication date |
---|---|
AU2014220668A1 (en) | 2015-08-20 |
US10174112B2 (en) | 2019-01-08 |
EP3896088A1 (en) | 2021-10-20 |
EP3521312B1 (en) | 2021-04-07 |
EP2958941A1 (en) | 2015-12-30 |
US11078275B2 (en) | 2021-08-03 |
ES2878749T3 (es) | 2021-11-19 |
JP6360077B2 (ja) | 2018-07-18 |
EP2958941B1 (en) | 2019-04-10 |
AU2014220668B2 (en) | 2018-12-13 |
CN105026427B (zh) | 2019-12-24 |
WO2014128221A1 (en) | 2014-08-28 |
US20160002345A1 (en) | 2016-01-07 |
CA2899241C (en) | 2023-03-28 |
ES2730011T3 (es) | 2019-11-07 |
EP3521312A1 (en) | 2019-08-07 |
US20190127463A1 (en) | 2019-05-02 |
CN105026427A (zh) | 2015-11-04 |
CA2899241A1 (en) | 2014-08-28 |
DK2958941T3 (da) | 2019-06-24 |
US20210363248A1 (en) | 2021-11-25 |
US20170298132A1 (en) | 2017-10-19 |
JP2016513104A (ja) | 2016-05-12 |
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