DK351982A - Fremgangsmaade til fremstilling af aminoglycosidderivater - Google Patents

Fremgangsmaade til fremstilling af aminoglycosidderivater Download PDF

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Publication number
DK351982A
DK351982A DK351982A DK351982A DK351982A DK 351982 A DK351982 A DK 351982A DK 351982 A DK351982 A DK 351982A DK 351982 A DK351982 A DK 351982A DK 351982 A DK351982 A DK 351982A
Authority
DK
Denmark
Prior art keywords
hydroxy
procedure
preparation
amino
aminoglycoside derivatives
Prior art date
Application number
DK351982A
Other languages
Danish (da)
English (en)
Inventor
H Loibner
W Streicher
P Stuetz
Original Assignee
Sandoz Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Ag filed Critical Sandoz Ag
Publication of DK351982A publication Critical patent/DK351982A/da

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/22—Cyclohexane rings, substituted by nitrogen atoms
    • C07H15/222—Cyclohexane rings substituted by at least two nitrogen atoms
    • C07H15/224—Cyclohexane rings substituted by at least two nitrogen atoms with only one saccharide radical directly attached to the cyclohexyl radical, e.g. destomycin, fortimicin, neamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/22—Cyclohexane rings, substituted by nitrogen atoms
    • C07H15/222—Cyclohexane rings substituted by at least two nitrogen atoms
    • C07H15/226—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings
    • C07H15/234—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings attached to non-adjacent ring carbon atoms of the cyclohexane rings, e.g. kanamycins, tobramycin, nebramycin, gentamicin A2

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Communicable Diseases (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK351982A 1981-08-07 1982-08-05 Fremgangsmaade til fremstilling af aminoglycosidderivater DK351982A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH510781 1981-08-07

Publications (1)

Publication Number Publication Date
DK351982A true DK351982A (da) 1983-02-08

Family

ID=4288039

Family Applications (1)

Application Number Title Priority Date Filing Date
DK351982A DK351982A (da) 1981-08-07 1982-08-05 Fremgangsmaade til fremstilling af aminoglycosidderivater

Country Status (13)

Country Link
US (1) US4503046A (pt)
EP (1) EP0072351B1 (pt)
JP (1) JPS5838299A (pt)
AT (1) ATE14437T1 (pt)
AU (1) AU8678682A (pt)
CA (1) CA1196629A (pt)
DE (1) DE3264906D1 (pt)
DK (1) DK351982A (pt)
ES (1) ES8402315A1 (pt)
FI (1) FI822671L (pt)
IL (1) IL66473A0 (pt)
PT (1) PT75385B (pt)
ZA (1) ZA825730B (pt)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3334383A1 (de) * 1982-09-30 1984-04-05 Sandoz-Patent-GmbH, 7850 Lörrach Neue aminglykosidderivate, verfahren zu ihrer herstellung und ihre verwendung
US4493831A (en) * 1982-10-25 1985-01-15 Fujisawa Pharmaceutical Co., Ltd. Aminoglycoside derivatives
US6653456B2 (en) * 2001-07-31 2003-11-25 Roche Diagnostics Corporation Site-specific aminoglycoside derivatives and their use in immunodiagnostic assays
US7794713B2 (en) * 2004-04-07 2010-09-14 Lpath, Inc. Compositions and methods for the treatment and prevention of hyperproliferative diseases
US20090074720A1 (en) * 2005-10-28 2009-03-19 Sabbadini Roger A Methods for decreasing immune response and treating immune conditions
US20080213274A1 (en) * 2005-10-28 2008-09-04 Sabbadini Roger A Compositions and methods for the treatment and prevention of fibrotic, inflammatory, and neovascularization conditions of the eye
US7862812B2 (en) * 2006-05-31 2011-01-04 Lpath, Inc. Methods for decreasing immune response and treating immune conditions

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4062947A (en) * 1975-11-04 1977-12-13 Schering Corporation Di-N-alkylaminoglycosides, methods for their manufacture and novel intermediates useful therein, method for their use as antibacterial agents and pharmaceutical compositions useful therefor
US4085208A (en) * 1976-06-21 1978-04-18 Schering Corporation Process for preparing 4,6-di-O-(aminoglycosyl)-1,3-diaminocyclitols and novel 1-epimers and 1-N-alkyl derivatives produced thereby; methods for the use of the 1-epimer derivatives as antibacterial agents and compositions useful therefor
DE2737264A1 (de) * 1977-08-18 1979-03-01 Bayer Ag Pseudotrisaccharide

Also Published As

Publication number Publication date
FI822671L (fi) 1983-02-08
PT75385A (en) 1982-09-01
IL66473A0 (en) 1982-12-31
ZA825730B (en) 1984-03-28
ES514767A0 (es) 1984-01-16
ES8402315A1 (es) 1984-01-16
JPS5838299A (ja) 1983-03-05
DE3264906D1 (en) 1985-08-29
CA1196629A (en) 1985-11-12
EP0072351B1 (en) 1985-07-24
PT75385B (en) 1985-06-28
FI822671A0 (fi) 1982-07-30
US4503046A (en) 1985-03-05
AU8678682A (en) 1983-02-10
ATE14437T1 (de) 1985-08-15
EP0072351A1 (en) 1983-02-16

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