DK3509598T3 - Ny anvendelse af triazolo(4,5-d)pyrimidinderivater til forebyggelse og behandling af bakteriel infektion - Google Patents
Ny anvendelse af triazolo(4,5-d)pyrimidinderivater til forebyggelse og behandling af bakteriel infektion Download PDFInfo
- Publication number
- DK3509598T3 DK3509598T3 DK17743050.1T DK17743050T DK3509598T3 DK 3509598 T3 DK3509598 T3 DK 3509598T3 DK 17743050 T DK17743050 T DK 17743050T DK 3509598 T3 DK3509598 T3 DK 3509598T3
- Authority
- DK
- Denmark
- Prior art keywords
- triazolo
- prevention
- treatment
- bacterial infection
- pyrimidine derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/90—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having two or more relevant hetero rings, condensed among themselves or with a common carbocyclic ring system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/54—Biologically active materials, e.g. therapeutic substances
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/404—Biocides, antimicrobial agents, antiseptic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/404—Biocides, antimicrobial agents, antiseptic agents
- A61L2300/406—Antibiotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2430/00—Materials or treatment for tissue regeneration
- A61L2430/20—Materials or treatment for tissue regeneration for reconstruction of the heart, e.g. heart valves
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP16188201.4A EP3292867B1 (en) | 2016-09-09 | 2016-09-09 | Triazolo(4,5-d)pyrimidine derivatives for use in the prevention and treatment of bacterial infection |
| PCT/EP2017/068811 WO2018046174A1 (en) | 2016-09-09 | 2017-07-25 | New use of triazolo(4,5-d)pyrimidine derivatives for prevention and treatment of bacterial infection |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK3509598T3 true DK3509598T3 (da) | 2020-12-21 |
Family
ID=56896425
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK16188201.4T DK3292867T3 (da) | 2016-09-09 | 2016-09-09 | Ny brug af triazol(4,5-d)pyrimidinderivater til brug i forebyggelsen og behandlingen af bakteriel infektion |
| DK17743050.1T DK3509598T3 (da) | 2016-09-09 | 2017-07-25 | Ny anvendelse af triazolo(4,5-d)pyrimidinderivater til forebyggelse og behandling af bakteriel infektion |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK16188201.4T DK3292867T3 (da) | 2016-09-09 | 2016-09-09 | Ny brug af triazol(4,5-d)pyrimidinderivater til brug i forebyggelsen og behandlingen af bakteriel infektion |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US20190194213A1 (da) |
| EP (2) | EP3292867B1 (da) |
| JP (1) | JP7075667B2 (da) |
| KR (1) | KR102401152B1 (da) |
| CN (1) | CN109689061B (da) |
| AU (1) | AU2017324655B2 (da) |
| BR (1) | BR112019003661A2 (da) |
| CA (1) | CA3035686C (da) |
| DK (2) | DK3292867T3 (da) |
| ES (2) | ES2731658T3 (da) |
| WO (1) | WO2018046174A1 (da) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3527571A1 (en) * | 2018-02-14 | 2019-08-21 | Université de Liège | Pyrimidine derivatives for prevention and treatment of bacterial infection |
| WO2020212553A1 (en) * | 2019-04-18 | 2020-10-22 | Université de Liège | New pyrimidine derivatives for prevention and treatment of gram-negative bacterial infection, contamination and fouling |
| GB201910656D0 (en) * | 2019-07-25 | 2019-09-11 | Univ Liege | New use of triazolo(4,5-d)Pyrimidine deerivatives |
| JP2024510363A (ja) | 2021-02-26 | 2024-03-07 | ユニベルシテ・ド・リエージュ | 新規の抗菌かつ抗血栓性の医療機器 |
| WO2023213198A1 (zh) * | 2022-05-04 | 2023-11-09 | 华东师范大学 | 芳香稠环化合物作为trek-1激活剂的用途、包含其的药物组合物、镇痛剂 |
| EP4289435A1 (en) | 2022-06-07 | 2023-12-13 | Université de Liège | N-alkyl-2-substituted atp analogues for use as antibacterial agent |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE9702773D0 (sv) * | 1997-07-22 | 1997-07-22 | Astra Pharma Prod | Novel compounds |
| TWI229674B (en) * | 1998-12-04 | 2005-03-21 | Astra Pharma Prod | Novel triazolo[4,5-d]pyrimidine compounds, pharmaceutical composition containing the same, their process for preparation and uses |
| GB0013407D0 (en) * | 2000-06-02 | 2000-07-26 | Astrazeneca Ab | Forms of a chemical compound |
| WO2009034386A1 (en) * | 2007-09-13 | 2009-03-19 | Astrazeneca Ab | Derivatives of adenine and 8-aza-adenine and uses thereof-796 |
| EP2459564B1 (en) * | 2009-07-27 | 2016-09-07 | Auspex Pharmaceuticals, Inc. | Cyclopropyl modulators of p2y12 receptor |
| CA2781182A1 (en) * | 2009-12-03 | 2011-06-09 | Astrazeneca Ab | Co - crystals of a triazolo [4,5 - d] pyrimidine platelet aggregation inhibitor |
| KR20140028011A (ko) * | 2011-06-01 | 2014-03-07 | 아스트라제네카 아베 | 신규한 티카그렐러 공결정 |
| EP2794575B1 (en) * | 2011-12-23 | 2018-12-05 | LEK Pharmaceuticals d.d. | Synthesis of triazolopyrimidine compounds |
| WO2013150495A2 (en) * | 2012-04-05 | 2013-10-10 | Dr. Reddy's Laboratories Limited | Preparation of ticagrelor |
| BR112014032085A2 (pt) * | 2012-06-29 | 2017-06-27 | Zentiva Ks | solvato de ticagrelor, processos para a preparação de um solvato e para a preparação de um cocristal, cocristal de ticagrelor, e, usos de um solvato e de um cocristal |
| WO2014006091A1 (en) * | 2012-07-04 | 2014-01-09 | Lek Pharmaceuticals D.D. | Ticagrelor adducts with divalent metal salts |
| CN104341423B (zh) * | 2013-08-02 | 2017-03-01 | 上海京新生物医药有限公司 | 替格瑞洛的一水合物及其制备方法与在制药中的应用 |
| WO2015162537A1 (en) * | 2014-04-23 | 2015-10-29 | Glenmark Pharmaceuticals Limited; Glenmark Generics Limited | Process for preparation of ticagrelor |
| WO2016116942A1 (en) * | 2015-01-20 | 2016-07-28 | Anlon Chemical Research Organization | Novel pharmaceutical compounds comprising ticagrelor with salts of aspirin |
-
2016
- 2016-09-09 DK DK16188201.4T patent/DK3292867T3/da active
- 2016-09-09 EP EP16188201.4A patent/EP3292867B1/en not_active Not-in-force
- 2016-09-09 ES ES16188201T patent/ES2731658T3/es active Active
-
2017
- 2017-07-25 KR KR1020197008453A patent/KR102401152B1/ko active IP Right Grant
- 2017-07-25 CN CN201780054753.2A patent/CN109689061B/zh active Active
- 2017-07-25 BR BR112019003661-0A patent/BR112019003661A2/pt active Search and Examination
- 2017-07-25 WO PCT/EP2017/068811 patent/WO2018046174A1/en unknown
- 2017-07-25 EP EP17743050.1A patent/EP3509598B1/en active Active
- 2017-07-25 JP JP2019513341A patent/JP7075667B2/ja active Active
- 2017-07-25 US US16/331,920 patent/US20190194213A1/en not_active Abandoned
- 2017-07-25 CA CA3035686A patent/CA3035686C/en active Active
- 2017-07-25 ES ES17743050T patent/ES2841742T3/es active Active
- 2017-07-25 DK DK17743050.1T patent/DK3509598T3/da active
- 2017-07-25 AU AU2017324655A patent/AU2017324655B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| WO2018046174A1 (en) | 2018-03-15 |
| US20190194213A1 (en) | 2019-06-27 |
| CA3035686C (en) | 2023-07-25 |
| BR112019003661A2 (pt) | 2019-05-21 |
| NZ751185A (en) | 2023-10-27 |
| EP3292867A1 (en) | 2018-03-14 |
| KR102401152B1 (ko) | 2022-05-24 |
| KR20190045237A (ko) | 2019-05-02 |
| CN109689061A (zh) | 2019-04-26 |
| DK3292867T3 (da) | 2019-07-22 |
| ES2841742T3 (es) | 2021-07-09 |
| JP2019529398A (ja) | 2019-10-17 |
| EP3509598A1 (en) | 2019-07-17 |
| CA3035686A1 (en) | 2018-03-15 |
| JP7075667B2 (ja) | 2022-05-26 |
| EP3292867B1 (en) | 2019-05-15 |
| AU2017324655A1 (en) | 2019-03-07 |
| ES2731658T3 (es) | 2019-11-18 |
| EP3509598B1 (en) | 2020-10-07 |
| AU2017324655B2 (en) | 2021-04-29 |
| CN109689061B (zh) | 2023-03-31 |
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