DK3829579T3 - 1,3,8-triazaspiro-forbindelser og anvendelse deraf som lægemidler til behandling af reperfusionsskader - Google Patents
1,3,8-triazaspiro-forbindelser og anvendelse deraf som lægemidler til behandling af reperfusionsskader Download PDFInfo
- Publication number
- DK3829579T3 DK3829579T3 DK19761959.6T DK19761959T DK3829579T3 DK 3829579 T3 DK3829579 T3 DK 3829579T3 DK 19761959 T DK19761959 T DK 19761959T DK 3829579 T3 DK3829579 T3 DK 3829579T3
- Authority
- DK
- Denmark
- Prior art keywords
- drugs
- treatment
- reperfusion injury
- triazaspiro compounds
- triazaspiro
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/438—The ring being spiro-condensed with carbocyclic or heterocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/10—Spiro-condensed systems
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT102018000007580A IT201800007580A1 (it) | 2018-07-27 | 2018-07-27 | Composti 1,3,8-triazaspiro e loro uso come medicamenti |
| PCT/IB2019/055962 WO2020021378A1 (en) | 2018-07-27 | 2019-07-12 | 1,3,8-triazaspiro compounds and their use as medicaments for the treatment of reperfusion injury |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK3829579T3 true DK3829579T3 (da) | 2023-10-30 |
Family
ID=63965817
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK19761959.6T DK3829579T3 (da) | 2018-07-27 | 2019-07-12 | 1,3,8-triazaspiro-forbindelser og anvendelse deraf som lægemidler til behandling af reperfusionsskader |
Country Status (6)
| Country | Link |
|---|---|
| EP (1) | EP3829579B1 (da) |
| DK (1) | DK3829579T3 (da) |
| ES (1) | ES2962134T3 (da) |
| IT (1) | IT201800007580A1 (da) |
| PT (1) | PT3829579T (da) |
| WO (1) | WO2020021378A1 (da) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20230286982A1 (en) * | 2020-08-11 | 2023-09-14 | Board Of Trustees Of Michigan State University | Proteasome enhancers and uses thereof |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE633914A (da) * | 1962-06-22 | |||
| US3155669A (en) * | 1962-06-22 | 1964-11-03 | Res Lab Dr C Janssen N V | 2, 4, 8-triaza-spiro (4, 5) dec-2-enes |
| AU779870B2 (en) * | 2000-01-20 | 2005-02-17 | Eisai R&D Management Co., Ltd. | Nitrogenous cyclic compounds and pharmaceutical compositions containing the same |
| NZ570181A (en) * | 2001-04-10 | 2010-02-26 | Ortho Mcneil Janssen Pharm | 1,3,8-Triazaspiro[4.5]decan-4-one derivatives useful for the treatment of ORL-1 receptor mediated disorders |
| AR046756A1 (es) * | 2003-12-12 | 2005-12-21 | Solvay Pharm Gmbh | Derivados de hidronopol como agonistas de receptores orl-1 humanos. |
-
2018
- 2018-07-27 IT IT102018000007580A patent/IT201800007580A1/it unknown
-
2019
- 2019-07-12 EP EP19761959.6A patent/EP3829579B1/en active Active
- 2019-07-12 ES ES19761959T patent/ES2962134T3/es active Active
- 2019-07-12 WO PCT/IB2019/055962 patent/WO2020021378A1/en unknown
- 2019-07-12 PT PT197619596T patent/PT3829579T/pt unknown
- 2019-07-12 DK DK19761959.6T patent/DK3829579T3/da active
Also Published As
| Publication number | Publication date |
|---|---|
| WO2020021378A1 (en) | 2020-01-30 |
| EP3829579A1 (en) | 2021-06-09 |
| IT201800007580A1 (it) | 2020-01-27 |
| PT3829579T (pt) | 2023-10-23 |
| EP3829579B1 (en) | 2023-08-02 |
| ES2962134T3 (es) | 2024-03-15 |
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