DK3506899T3 - Præparater og fremgangsmåder til diagnosticering og behandling af lymfesystemlidelser - Google Patents
Præparater og fremgangsmåder til diagnosticering og behandling af lymfesystemlidelser Download PDFInfo
- Publication number
- DK3506899T3 DK3506899T3 DK17847498.7T DK17847498T DK3506899T3 DK 3506899 T3 DK3506899 T3 DK 3506899T3 DK 17847498 T DK17847498 T DK 17847498T DK 3506899 T3 DK3506899 T3 DK 3506899T3
- Authority
- DK
- Denmark
- Prior art keywords
- diagnosing
- preparations
- methods
- system disorders
- lymphatic system
- Prior art date
Links
- 208000018555 lymphatic system disease Diseases 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 238000002360 preparation method Methods 0.000 title 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/436—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having oxygen as a ring hetero atom, e.g. rapamycin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/50—Pyridazines; Hydrogenated pyridazines
- A61K31/501—Pyridazines; Hydrogenated pyridazines not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/156—Polymorphic or mutational markers
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Analytical Chemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pathology (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Physics & Mathematics (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662382147P | 2016-08-31 | 2016-08-31 | |
| PCT/US2017/049453 WO2018045078A2 (en) | 2016-08-31 | 2017-08-30 | Compositions and methods for the diagnosis and treatment of lymphatic system disorders |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK3506899T3 true DK3506899T3 (da) | 2022-03-07 |
Family
ID=61309356
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK17847498.7T DK3506899T3 (da) | 2016-08-31 | 2017-08-30 | Præparater og fremgangsmåder til diagnosticering og behandling af lymfesystemlidelser |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US11401553B2 (enExample) |
| EP (2) | EP3506899B1 (enExample) |
| JP (3) | JP7202287B2 (enExample) |
| AU (2) | AU2017319507B2 (enExample) |
| CA (1) | CA3034786A1 (enExample) |
| DK (1) | DK3506899T3 (enExample) |
| ES (1) | ES2906333T3 (enExample) |
| WO (1) | WO2018045078A2 (enExample) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3846851A4 (en) * | 2018-09-07 | 2022-09-21 | The Children's Hospital Of Philadelphia | COMPOSITIONS AND METHODS FOR DIAGNOSING AND TREATING DISORDERS OF THE LYMPHATIC SYSTEM |
| WO2021231814A1 (en) * | 2020-05-14 | 2021-11-18 | The Trustees Of Columbia University In The City Of New York | Compositions and methods for the treatment and prevention of vascular malformations |
| US12070468B2 (en) * | 2020-05-14 | 2024-08-27 | The Trustees Of Columbia University In The City Of New York | Compositions and methods for the treatment and prevention of vascular malformations |
| WO2023229605A1 (en) * | 2022-05-27 | 2023-11-30 | Avalo Therapeutics, Inc. | Methods and treatment for complex lymphatic malformations |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9212416D0 (en) | 1992-06-11 | 1992-07-22 | Medical Res Council | Reversible binding substances |
| US6057098A (en) | 1997-04-04 | 2000-05-02 | Biosite Diagnostics, Inc. | Polyvalent display libraries |
| US20080131887A1 (en) * | 2006-11-30 | 2008-06-05 | Stephan Dietrich A | Genetic Analysis Systems and Methods |
| US9018912B2 (en) | 2011-05-17 | 2015-04-28 | Inphi Corporation | System and method for managing parallel-connected battery cells |
| WO2014210538A1 (en) | 2013-06-28 | 2014-12-31 | The Regents Of The University Of California | Treating cognitive deficits associated with noonan syndrome |
| EP3738592B1 (en) * | 2013-10-08 | 2022-01-26 | AI Therapeutics, Inc. | Rapamycin for the treatment of lymphangioleiomyomatosis |
| EP3984537B1 (en) * | 2013-12-20 | 2024-03-20 | Biomed Valley Discoveries, Inc. | Cancer treatments using combinations of type 2 mek and erk inhibitors |
| JP6429306B2 (ja) * | 2014-03-26 | 2018-11-28 | 国立大学法人東北大学 | Ｃｆｃ症候群モデルマウスの作製とその治療法の確立 |
| US11104955B2 (en) | 2016-12-30 | 2021-08-31 | Children's Medical Center Corporation | MAP2K1 (MEK1) as a therapeutic target for arteriovenous malformations and associated disorders |
-
2017
- 2017-08-30 US US16/327,060 patent/US11401553B2/en active Active
- 2017-08-30 ES ES17847498T patent/ES2906333T3/es active Active
- 2017-08-30 CA CA3034786A patent/CA3034786A1/en active Pending
- 2017-08-30 EP EP17847498.7A patent/EP3506899B1/en active Active
- 2017-08-30 AU AU2017319507A patent/AU2017319507B2/en active Active
- 2017-08-30 WO PCT/US2017/049453 patent/WO2018045078A2/en not_active Ceased
- 2017-08-30 JP JP2019511562A patent/JP7202287B2/ja active Active
- 2017-08-30 EP EP21214113.9A patent/EP4023769A1/en active Pending
- 2017-08-30 DK DK17847498.7T patent/DK3506899T3/da active
-
2022
- 2022-07-28 US US17/815,647 patent/US20230048706A1/en active Pending
- 2022-12-23 JP JP2022206535A patent/JP2023052057A/ja not_active Withdrawn
-
2024
- 2024-02-21 AU AU2024201122A patent/AU2024201122A1/en active Pending
- 2024-09-30 JP JP2024169918A patent/JP2025016454A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| WO2018045078A3 (en) | 2019-04-25 |
| EP4023769A1 (en) | 2022-07-06 |
| WO2018045078A2 (en) | 2018-03-08 |
| CA3034786A1 (en) | 2018-03-08 |
| EP3506899B1 (en) | 2021-12-15 |
| JP2023052057A (ja) | 2023-04-11 |
| US11401553B2 (en) | 2022-08-02 |
| AU2017319507B2 (en) | 2023-11-23 |
| JP2019533987A (ja) | 2019-11-28 |
| AU2024201122A1 (en) | 2024-03-14 |
| EP3506899A4 (en) | 2020-05-20 |
| AU2017319507A1 (en) | 2019-03-14 |
| US20230048706A1 (en) | 2023-02-16 |
| JP2025016454A (ja) | 2025-02-04 |
| ES2906333T3 (es) | 2022-04-18 |
| US20200056238A1 (en) | 2020-02-20 |
| EP3506899A2 (en) | 2019-07-10 |
| JP7202287B2 (ja) | 2023-01-11 |
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