DK349581A - C-076 makrolider og fremgangsmaade til fremstilling deraf - Google Patents
C-076 makrolider og fremgangsmaade til fremstilling derafInfo
- Publication number
- DK349581A DK349581A DK349581A DK349581A DK349581A DK 349581 A DK349581 A DK 349581A DK 349581 A DK349581 A DK 349581A DK 349581 A DK349581 A DK 349581A DK 349581 A DK349581 A DK 349581A
- Authority
- DK
- Denmark
- Prior art keywords
- chem
- compounds
- makrolides
- procedures
- producing
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/01—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing oxygen
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/195—Antibiotics
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
- C12N1/205—Bacterial isolates
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
- C12P17/18—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
- C12P17/181—Heterocyclic compounds containing oxygen atoms as the only ring heteroatoms in the condensed system, e.g. Salinomycin, Septamycin
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/44—Preparation of O-glycosides, e.g. glucosides
- C12P19/60—Preparation of O-glycosides, e.g. glucosides having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin
- C12P19/62—Preparation of O-glycosides, e.g. glucosides having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin the hetero ring having eight or more ring members and only oxygen as ring hetero atoms, e.g. erythromycin, spiramycin, nystatin
- C12P19/623—Avermectin; Milbemycin; Ivermectin; C-076
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
- C12R2001/00—Microorganisms ; Processes using microorganisms
- C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
- C12R2001/465—Streptomyces
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- General Engineering & Computer Science (AREA)
- Polymers & Plastics (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Molecular Biology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Tropical Medicine & Parasitology (AREA)
- Virology (AREA)
- Biomedical Technology (AREA)
- Animal Husbandry (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Enzymes And Modification Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US06/175,615 US4285963A (en) | 1980-08-07 | 1980-08-07 | Novel derivatives of C-076 compounds |
Publications (1)
Publication Number | Publication Date |
---|---|
DK349581A true DK349581A (da) | 1982-02-08 |
Family
ID=22640941
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK349581A DK349581A (da) | 1980-08-07 | 1981-08-06 | C-076 makrolider og fremgangsmaade til fremstilling deraf |
Country Status (13)
Country | Link |
---|---|
US (1) | US4285963A (ja) |
EP (1) | EP0046045B1 (ja) |
JP (1) | JPS5759892A (ja) |
AT (1) | ATE4167T1 (ja) |
AU (1) | AU541097B2 (ja) |
CA (1) | CA1160169A (ja) |
DE (1) | DE3160652D1 (ja) |
DK (1) | DK349581A (ja) |
ES (1) | ES8302092A1 (ja) |
GR (1) | GR74278B (ja) |
NZ (1) | NZ197860A (ja) |
PT (1) | PT73470B (ja) |
ZA (1) | ZA815406B (ja) |
Families Citing this family (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4429042A (en) | 1978-09-08 | 1984-01-31 | Merck & Co., Inc. | Strain of Streptomyces for producing antiparasitic compounds |
US4378353A (en) * | 1981-02-17 | 1983-03-29 | Merck & Co., Inc. | Novel C-076 compounds |
US4333925A (en) * | 1981-05-11 | 1982-06-08 | Merck & Co., Inc. | Derivatives of C-076 compounds |
US4412991A (en) * | 1981-08-28 | 1983-11-01 | Merck & Co., Inc. | 22-Hydroxy derivatives of C-076 compounds, pharmaceutical compositions and method of use |
US4423211A (en) * | 1981-12-21 | 1983-12-27 | Merck & Co., Inc. | Process for the whole broth extraction of avermectin |
US5198464A (en) * | 1984-06-05 | 1993-03-30 | American Cyanamid Company | Method and compositions for helmintic, arthropod ectoparasitic and acaridal infections with novel agents |
US5317030A (en) * | 1984-06-05 | 1994-05-31 | American Cyanamid Company | Method and compositions for helmintic, arthropod ectoparasitic and acaridal infections with novel agents |
US5106994A (en) * | 1984-06-05 | 1992-04-21 | American Cyanamid Company | Agents and method of production thereof |
US5169956A (en) * | 1984-06-05 | 1992-12-08 | American Cyanamid Company | Macrolide antibiotic compounds |
EP0180539A1 (de) * | 1984-09-18 | 1986-05-07 | Ciba-Geigy Ag | 13-Halo- und 13-Hydroximilbemycine |
GB2168345B (en) * | 1984-12-14 | 1988-05-25 | Ciba Geigy Ag | Pesticidal 13b-substituted milbemycin derivatives |
ES8800986A1 (es) * | 1985-07-27 | 1987-12-01 | Pfizer | Un procedimiento para la produccion de un nuevo derivado de avermectina |
US5840704A (en) * | 1986-07-16 | 1998-11-24 | Pfizer Inc. | Antiparasitic agents and process for their preparation |
US5525506A (en) * | 1987-01-23 | 1996-06-11 | Pfizer Inc. | Process for production of avermectins and cultures therefor |
US5238848A (en) * | 1987-01-23 | 1993-08-24 | Pfizer Inc | Cultures for production of avermectins |
US5234831A (en) * | 1987-01-23 | 1993-08-10 | Pfizer Inc | Cultures for production of B avermectins |
US5240850A (en) * | 1987-10-23 | 1993-08-31 | Pfizer Inc. | Cultures for production of avermectin aglycones |
DE3888936T2 (de) * | 1987-11-03 | 1994-07-21 | Beecham Group Plc | Zwischenprodukte für die Herstellung makrolider Antibiotika mit anthelmintischer Wirkung. |
ES2045146T3 (es) * | 1987-11-09 | 1994-01-16 | Pfizer | Avermectinas etiladas. |
GB8726730D0 (en) * | 1987-11-14 | 1987-12-16 | Pfizer Ltd | Antiparasitic agents |
US5008250A (en) * | 1988-05-25 | 1991-04-16 | Merck & Co., Inc. | Avermectins with a cleaved furan ring and an 8a hydroxy group |
US5188944A (en) * | 1990-06-22 | 1993-02-23 | Merck & Co., Inc. | Process for the glycosylation of avermectin agylcones |
US6103504A (en) * | 1992-03-25 | 2000-08-15 | Pfizer Inc. | Process for production of avermectins and cultures therefor |
GB9226525D0 (en) * | 1992-12-19 | 1993-02-10 | Pfizer Ltd | Antiparasitic agents |
US8980896B2 (en) | 2009-12-17 | 2015-03-17 | Merial, Inc. | Compositions comprising macrocyclic lactone compounds and spirodioxepinoindoles |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3950360A (en) * | 1972-06-08 | 1976-04-13 | Sankyo Company Limited | Antibiotic substances |
US3998699A (en) * | 1972-06-08 | 1976-12-21 | Sankyo Company Limited | Antibiotic substances B-41, their production and their use as insecticides and acaricides |
SE434277B (sv) * | 1976-04-19 | 1984-07-16 | Merck & Co Inc | Sett att framstella nya antihelmintiskt verkande foreningar genom odling av streptomyces avermitilis |
US4093629A (en) * | 1977-04-11 | 1978-06-06 | Merck & Co., Inc. | Derivatives of antibiotic substance milbemycin and processes therefor |
NZ188459A (en) * | 1977-10-03 | 1982-09-07 | Merck & Co Inc | Derivatives of c-076 compounds and pesticidal compositions |
US4161583A (en) * | 1977-10-03 | 1979-07-17 | Merck & Co., Inc. | Method for the separation and purification of antibiotic macrolides |
US4172940A (en) * | 1977-10-03 | 1979-10-30 | Merck & Co., Inc. | Purification of C-076 compounds by single column chromatography |
PH15982A (en) * | 1977-10-03 | 1983-05-18 | Merck & Co Inc | Selective hydrogenation producta of c-076 compounds and derivatives thereof |
US4173571A (en) * | 1977-12-19 | 1979-11-06 | Merck & Co., Inc. | 13-Halo and 13-deoxy derivatives of C-076 compounds |
US4171314A (en) * | 1977-12-19 | 1979-10-16 | Merck & Co., Inc. | 13-Halo and 13-deoxy C-076 compounds |
US4200581A (en) * | 1978-08-04 | 1980-04-29 | Merck & Co., Inc. | Alkyl derivatives of C-076 compounds |
-
1980
- 1980-08-07 US US06/175,615 patent/US4285963A/en not_active Expired - Lifetime
-
1981
- 1981-07-27 NZ NZ197860A patent/NZ197860A/en unknown
- 1981-07-31 GR GR65691A patent/GR74278B/el unknown
- 1981-08-03 EP EP81303543A patent/EP0046045B1/en not_active Expired
- 1981-08-03 PT PT73470A patent/PT73470B/pt unknown
- 1981-08-03 DE DE8181303543T patent/DE3160652D1/de not_active Expired
- 1981-08-03 AT AT81303543T patent/ATE4167T1/de not_active IP Right Cessation
- 1981-08-04 CA CA000383192A patent/CA1160169A/en not_active Expired
- 1981-08-05 ES ES504576A patent/ES8302092A1/es not_active Expired
- 1981-08-05 AU AU73820/81A patent/AU541097B2/en not_active Ceased
- 1981-08-06 ZA ZA815406A patent/ZA815406B/xx unknown
- 1981-08-06 DK DK349581A patent/DK349581A/da not_active Application Discontinuation
- 1981-08-07 JP JP56123170A patent/JPS5759892A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
AU7382081A (en) | 1982-02-11 |
ZA815406B (en) | 1983-03-30 |
EP0046045A1 (en) | 1982-02-17 |
GR74278B (ja) | 1984-06-21 |
AU541097B2 (en) | 1984-12-13 |
CA1160169A (en) | 1984-01-10 |
ATE4167T1 (de) | 1983-08-15 |
NZ197860A (en) | 1985-02-28 |
ES504576A0 (es) | 1983-01-01 |
PT73470B (en) | 1983-09-01 |
PT73470A (en) | 1981-09-01 |
EP0046045B1 (en) | 1983-07-20 |
ES8302092A1 (es) | 1983-01-01 |
DE3160652D1 (en) | 1983-08-25 |
US4285963A (en) | 1981-08-25 |
JPS5759892A (en) | 1982-04-10 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
ATS | Application withdrawn |