DK3448430T3 - Anvendelse af en acetylcholinesterase-inhibitor og idalopirdin til reduktion af fald hos patienter med parkinsons sygdom - Google Patents

Anvendelse af en acetylcholinesterase-inhibitor og idalopirdin til reduktion af fald hos patienter med parkinsons sygdom Download PDF

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Publication number
DK3448430T3
DK3448430T3 DK17719255.6T DK17719255T DK3448430T3 DK 3448430 T3 DK3448430 T3 DK 3448430T3 DK 17719255 T DK17719255 T DK 17719255T DK 3448430 T3 DK3448430 T3 DK 3448430T3
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DK
Denmark
Prior art keywords
idalopirdine
parkinson
patients
disease
acetylcholinesterase inhibitor
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DK17719255.6T
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English (en)
Inventor
Jong Inge E M De
Martin Sarter
Aaron Kucinski
Original Assignee
H Lundbeck As
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Publication of DK3448430T3 publication Critical patent/DK3448430T3/da

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404Indoles, e.g. pindolol
    • A61K31/4045Indole-alkylamines; Amides thereof, e.g. serotonin, melatonin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/27Esters, e.g. nitroglycerine, selenocyanates of carbamic or thiocarbamic acids, meprobamate, carbachol, neostigmine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Emergency Medicine (AREA)
  • Psychology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK17719255.6T 2016-04-26 2017-04-25 Anvendelse af en acetylcholinesterase-inhibitor og idalopirdin til reduktion af fald hos patienter med parkinsons sygdom DK3448430T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DKPA201600248 2016-04-26
PCT/EP2017/059739 WO2017186686A1 (en) 2016-04-26 2017-04-25 Use of an acetylcholinesterase inhibitor and idalopirdine for reducing falls in parkinson's disease patients

Publications (1)

Publication Number Publication Date
DK3448430T3 true DK3448430T3 (da) 2023-07-03

Family

ID=58632402

Family Applications (1)

Application Number Title Priority Date Filing Date
DK17719255.6T DK3448430T3 (da) 2016-04-26 2017-04-25 Anvendelse af en acetylcholinesterase-inhibitor og idalopirdin til reduktion af fald hos patienter med parkinsons sygdom

Country Status (27)

Country Link
US (1) US10383849B2 (da)
EP (1) EP3448430B1 (da)
JP (1) JP6992004B2 (da)
KR (1) KR102473545B1 (da)
CN (1) CN109069650A (da)
AU (1) AU2017256623B2 (da)
BR (1) BR112017026928B1 (da)
CA (1) CA3020557A1 (da)
CL (1) CL2018003013A1 (da)
CY (1) CY1126138T1 (da)
DK (1) DK3448430T3 (da)
ES (1) ES2949288T3 (da)
FI (1) FI3448430T3 (da)
HR (1) HRP20230693T8 (da)
HU (1) HUE062626T2 (da)
IL (1) IL262546B (da)
LT (1) LT3448430T (da)
MX (1) MX2018013031A (da)
PL (1) PL3448430T3 (da)
PT (1) PT3448430T (da)
RS (1) RS64307B1 (da)
RU (1) RU2742173C2 (da)
SG (1) SG11201809297UA (da)
SI (1) SI3448430T1 (da)
TW (1) TW201806621A (da)
WO (1) WO2017186686A1 (da)
ZA (1) ZA201806864B (da)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111032038A (zh) * 2017-05-24 2020-04-17 H.隆德贝克有限公司 用于治疗阿尔茨海默氏病的药物组合
JP2021515801A (ja) * 2017-12-22 2021-06-24 ニューロセア,エルエルシー 神経変性疾患における転倒および転倒頻度に関連する処置のための組成物および方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9818914D0 (en) * 1998-08-28 1998-10-21 Smithkline Beecham Plc Use
CZ305838B6 (cs) * 2001-03-29 2016-04-06 Eli Lilly And Company N-(2-arylethyl)benzylaminy jako antagonisté receptoru 5-HT6
AU2006232517A1 (en) * 2005-04-04 2006-10-12 Eisai R&D Management Co., Ltd. Dihydropyridine compounds and compositions for headaches
PE20071143A1 (es) * 2006-01-13 2008-01-20 Wyeth Corp Composicion farmaceutica que comprende un inhibidor de acetilcolinesterasa y un antagonista 5-hidroxitriptamina-6
WO2007147883A1 (en) * 2006-06-23 2007-12-27 Laboratorios Del Dr. Esteve, S.A. Combination of a cholinesterase inhibitor and a compound with 5-ht6 receptor affinity
EP2254564A1 (en) * 2007-12-12 2010-12-01 Glaxo Group Limited Combinations comprising 3-phenylsulfonyl-8-piperazinyl-1yl-quinoline
RU2393158C1 (ru) * 2008-10-06 2010-06-27 Андрей Александрович Иващенко ЗАМЕЩЕННЫЕ 3-АРИЛСУЛЬФОНИЛ-ПИРАЗОЛО[1,5-а]ПИРИМИДИНЫ, АНТАГОНИСТЫ СЕРОТОНИНОВЫХ 5-HT6 РЕЦЕПТОРОВ, СПОСОБЫ ИХ ПОЛУЧЕНИЯ И ПРИМЕНЕНИЯ
JO3459B1 (ar) * 2012-09-09 2020-07-05 H Lundbeck As تركيبات صيدلانية لعلاج مرض الزهايمر

Also Published As

Publication number Publication date
RU2018135846A (ru) 2020-05-26
ZA201806864B (en) 2020-01-29
CL2018003013A1 (es) 2018-12-14
LT3448430T (lt) 2023-07-25
HRP20230693T8 (hr) 2023-11-10
PL3448430T3 (pl) 2023-08-21
TW201806621A (zh) 2018-03-01
JP2019519480A (ja) 2019-07-11
ES2949288T3 (es) 2023-09-27
SI3448430T1 (sl) 2023-08-31
RS64307B1 (sr) 2023-07-31
SG11201809297UA (en) 2018-11-29
EP3448430B1 (en) 2023-06-07
AU2017256623B2 (en) 2022-07-21
BR112017026928A2 (pt) 2018-08-14
CY1126138T1 (el) 2023-11-15
PT3448430T (pt) 2023-07-11
US20170304267A1 (en) 2017-10-26
IL262546B (en) 2022-05-01
JP6992004B2 (ja) 2022-02-03
KR20180133869A (ko) 2018-12-17
RU2018135846A3 (da) 2020-09-30
CN109069650A (zh) 2018-12-21
EP3448430A1 (en) 2019-03-06
IL262546A (en) 2018-12-31
CA3020557A1 (en) 2017-11-02
RU2742173C2 (ru) 2021-02-02
WO2017186686A1 (en) 2017-11-02
HRP20230693T1 (hr) 2023-10-13
HUE062626T2 (hu) 2023-11-28
FI3448430T3 (fi) 2023-06-20
AU2017256623A1 (en) 2018-11-01
MX2018013031A (es) 2019-01-17
KR102473545B1 (ko) 2022-12-01
BR112017026928B1 (pt) 2023-04-11
US10383849B2 (en) 2019-08-20

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