DK3430149T3 - Forbedrede Tornerose-transposoner, kits og fremgangsmåder til transponering - Google Patents

Forbedrede Tornerose-transposoner, kits og fremgangsmåder til transponering Download PDF

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Publication number
DK3430149T3
DK3430149T3 DK17710552.5T DK17710552T DK3430149T3 DK 3430149 T3 DK3430149 T3 DK 3430149T3 DK 17710552 T DK17710552 T DK 17710552T DK 3430149 T3 DK3430149 T3 DK 3430149T3
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DK
Denmark
Prior art keywords
kits
sleeping beauty
transposition methods
improved sleeping
beauty transposons
Prior art date
Application number
DK17710552.5T
Other languages
English (en)
Inventor
Christopher Kaufmann
Zsuzsanna Izsvák
Zoltán Ivics
Suneel Narayanavari
Original Assignee
Max Delbrueck Centrum Fuer Molekulare Medizin Helmholtz Gemeinschaft
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Application filed by Max Delbrueck Centrum Fuer Molekulare Medizin Helmholtz Gemeinschaft filed Critical Max Delbrueck Centrum Fuer Molekulare Medizin Helmholtz Gemeinschaft
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Publication of DK3430149T3 publication Critical patent/DK3430149T3/da

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/87Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • C12N15/90Stable introduction of foreign DNA into chromosome
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2800/00Nucleic acids vectors
    • C12N2800/90Vectors containing a transposable element

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • General Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Plant Pathology (AREA)
  • Mycology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Virology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
DK17710552.5T 2016-03-15 2017-03-15 Forbedrede Tornerose-transposoner, kits og fremgangsmåder til transponering DK3430149T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP16160499.6A EP3219803A1 (en) 2016-03-15 2016-03-15 Enhanced sleeping beauty transposons, kits and methods of transposition
PCT/EP2017/056133 WO2017158029A1 (en) 2016-03-15 2017-03-15 Enhanced sleeping beauty transposons, kits and methods of transposition

Publications (1)

Publication Number Publication Date
DK3430149T3 true DK3430149T3 (da) 2021-07-26

Family

ID=55588085

Family Applications (1)

Application Number Title Priority Date Filing Date
DK17710552.5T DK3430149T3 (da) 2016-03-15 2017-03-15 Forbedrede Tornerose-transposoner, kits og fremgangsmåder til transponering

Country Status (11)

Country Link
US (1) US11814643B2 (da)
EP (2) EP3219803A1 (da)
JP (1) JP7072897B2 (da)
KR (1) KR102476276B1 (da)
CN (1) CN109072257B (da)
AU (2) AU2017232265B2 (da)
CA (1) CA3015139A1 (da)
DK (1) DK3430149T3 (da)
ES (1) ES2884205T3 (da)
HK (1) HK1258956A1 (da)
WO (1) WO2017158029A1 (da)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107557482B (zh) * 2017-10-26 2020-04-14 浙江海洋大学 一种快速鉴别南、北疆分布的新疆裸重唇鱼的分子生物学方法
WO2021046243A2 (en) 2019-09-03 2021-03-11 Myeloid Therapeutics, Inc. Methods and compositions for genomic integration
CN113584083A (zh) 2020-04-30 2021-11-02 深圳市深研生物科技有限公司 用于逆转录病毒载体的生产细胞和包装细胞及其制备方法
KR102365768B1 (ko) 2020-07-22 2022-02-18 인천대학교 산학협력단 개선된 슬리핑 뷰티 트랜스포존 시스템 및 이를 이용한 유전자 전위 방법
WO2023212691A1 (en) 2022-04-28 2023-11-02 Immatics US, Inc. DOMINANT NEGATIVE TGFβ RECEPTOR POLYPEPTIDES, CD8 POLYPEPTIDES, CELLS, COMPOSITIONS, AND METHODS OF USING THEREOF
US20240066127A1 (en) 2022-04-28 2024-02-29 Immatics US, Inc. Il-12 polypeptides, il-15 polypeptides, il-18 polypeptides, cd8 polypeptides, compositions, and methods of using thereof
WO2023212697A1 (en) 2022-04-28 2023-11-02 Immatics US, Inc. Membrane-bound il-15, cd8 polypeptides, cells, compositions, and methods of using thereof
US20240000844A1 (en) 2022-05-27 2024-01-04 Kite Pharma, Inc. Non-viral delivery of cell therapy constructs

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6489458B2 (en) 1997-03-11 2002-12-03 Regents Of The University Of Minnesota DNA-based transposon system for the introduction of nucleic acid into DNA of a cell
KR100985678B1 (ko) * 2002-01-09 2010-10-05 에라스무스 유니버시티 메디컬 센터 로테르담 형질전환된 생물체에서 전위인자 벡터에 의해 전위를유발시키는 방법
WO2003089618A2 (en) * 2002-04-22 2003-10-30 Regents Of The University Of Minnesota Transposon system and methods of use
US7919583B2 (en) * 2005-08-08 2011-04-05 Discovery Genomics, Inc. Integration-site directed vector systems
US20100122356A1 (en) * 2007-03-07 2010-05-13 Aarhus Universitet Pig model for psoriasis
EP2160461B1 (en) 2007-07-04 2012-08-08 Max-Delbrück-Centrum für Molekulare Medizin (MDC) Hyperactive variants of the transposase protein of the transposon system sleeping beauty
CN101289671B (zh) * 2008-05-30 2010-12-22 扬州大学 一种转基因动物的制备方法
IN2014DN10996A (da) * 2012-05-30 2015-09-25 Baylor College Medicine
SG10201803758XA (en) * 2013-02-01 2018-06-28 Selexis Sa Enhanced Transgene Expression and Processing
CN105255895B (zh) * 2015-11-06 2018-01-02 爱博环球生物技术有限公司 用于真核细胞系的提高蛋白表达水平的mar转录调控元件及其表达系统
EP3219800A1 (en) * 2016-03-15 2017-09-20 Max-Delbrück-Centrum Für Molekulare Medizin A transposon-based transfection system for primary cells

Also Published As

Publication number Publication date
EP3430149A1 (en) 2019-01-23
KR102476276B1 (ko) 2022-12-09
US20190169638A1 (en) 2019-06-06
JP2019509066A (ja) 2019-04-04
CN109072257A (zh) 2018-12-21
AU2022263525A1 (en) 2022-12-08
EP3219803A1 (en) 2017-09-20
JP7072897B2 (ja) 2022-05-23
ES2884205T3 (es) 2021-12-10
KR20180127358A (ko) 2018-11-28
CN109072257B (zh) 2022-11-04
AU2017232265A1 (en) 2018-08-30
US11814643B2 (en) 2023-11-14
CA3015139A1 (en) 2017-09-21
AU2017232265B2 (en) 2022-08-11
HK1258956A1 (zh) 2019-11-22
WO2017158029A1 (en) 2017-09-21
EP3430149B1 (en) 2021-05-05

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