DK3418273T3 - Derivater af flavagliner - Google Patents
Derivater af flavagliner Download PDFInfo
- Publication number
- DK3418273T3 DK3418273T3 DK18187037.9T DK18187037T DK3418273T3 DK 3418273 T3 DK3418273 T3 DK 3418273T3 DK 18187037 T DK18187037 T DK 18187037T DK 3418273 T3 DK3418273 T3 DK 3418273T3
- Authority
- DK
- Denmark
- Prior art keywords
- flavaglines
- derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
- C07D491/044—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
- C07D491/048—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring the oxygen-containing ring being five-membered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Furan Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR1456474A FR3023290B1 (fr) | 2014-07-04 | 2014-07-04 | Derives de flavaglines |
| EP15733767.6A EP3164393B1 (fr) | 2014-07-04 | 2015-07-06 | Dérivés de flavaglines |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK3418273T3 true DK3418273T3 (da) | 2022-03-21 |
Family
ID=52016681
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK18187037.9T DK3418273T3 (da) | 2014-07-04 | 2015-07-06 | Derivater af flavagliner |
| DK15733767.6T DK3164393T3 (en) | 2014-07-04 | 2015-07-06 | Flavagline derivatives |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK15733767.6T DK3164393T3 (en) | 2014-07-04 | 2015-07-06 | Flavagline derivatives |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US10047064B2 (enExample) |
| EP (3) | EP3164393B1 (enExample) |
| JP (4) | JP6637954B2 (enExample) |
| DK (2) | DK3418273T3 (enExample) |
| ES (2) | ES2908225T3 (enExample) |
| FR (1) | FR3023290B1 (enExample) |
| PL (2) | PL3164393T3 (enExample) |
| TR (1) | TR201819805T4 (enExample) |
| WO (1) | WO2016001441A1 (enExample) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR3023290B1 (fr) * | 2014-07-04 | 2016-08-19 | Pf Medicament | Derives de flavaglines |
| ES2974439T3 (es) | 2015-11-25 | 2024-06-27 | Effector Therapeutics Inc | Compuestos inhibidores de EIF4-A y métodos relacionados con los mismos |
| LT3643707T (lt) * | 2017-06-19 | 2022-05-25 | Futurechem Co., Ltd. | 18f žymėtas junginys, skirtas prostatos vėžio diagnostikai ir jo panaudojimas |
| AU2019221837B2 (en) * | 2018-02-19 | 2024-08-01 | Memorial Sloan-Kettering Cancer Center | Agents and methods for treating dysproliferative diseases |
| WO2020076889A1 (en) * | 2018-10-09 | 2020-04-16 | The Research Institute At Nationwide Children's Hospital | Anticancer rocaglamide derivatives |
| WO2020086562A1 (en) * | 2018-10-22 | 2020-04-30 | Trustees Of Boston University | Compositions and methods for inhibiting viral infection |
| IL291979B1 (en) | 2019-10-10 | 2025-08-01 | Cellectar Biosciences Inc | Phospholipid-flavagline conjugates and methods of using the same for targeted cancer therapy |
| WO2025104293A1 (en) * | 2023-11-17 | 2025-05-22 | Gustave Roussy Transfert | Inhibitors of eif4a and uses thereof |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AUPQ866500A0 (en) * | 2000-07-05 | 2000-08-03 | Exgenix Operations Pty Ltd | Therapeutic compounds and methods |
| DE102004024504A1 (de) * | 2004-05-18 | 2006-02-16 | Bayer Healthcare Ag | Neue Cylopenta[b]benzofuran-Derivate und ihre Verwendung |
| WO2007139749A2 (en) * | 2006-05-22 | 2007-12-06 | Trustees Of Boston University | Asymmetric synthesis of rocaglamides via enantioselective photocycloaddition mediated by chiral bronsted acids |
| EP2189453A1 (en) * | 2008-11-25 | 2010-05-26 | Université Louis Pasteur | Rocaglaol derivatives as cardioprotectant agents |
| CN102300568A (zh) | 2008-12-05 | 2011-12-28 | 赢泰医药科技发展有限公司 | Hif-1蛋白积聚的抑制剂 |
| FR3023290B1 (fr) * | 2014-07-04 | 2016-08-19 | Pf Medicament | Derives de flavaglines |
-
2014
- 2014-07-04 FR FR1456474A patent/FR3023290B1/fr active Active
-
2015
- 2015-07-06 TR TR2018/19805T patent/TR201819805T4/tr unknown
- 2015-07-06 JP JP2017500083A patent/JP6637954B2/ja active Active
- 2015-07-06 EP EP15733767.6A patent/EP3164393B1/fr active Active
- 2015-07-06 US US15/323,650 patent/US10047064B2/en active Active
- 2015-07-06 ES ES18187037T patent/ES2908225T3/es active Active
- 2015-07-06 EP EP18187037.9A patent/EP3418273B1/fr active Active
- 2015-07-06 ES ES15733767T patent/ES2700156T3/es active Active
- 2015-07-06 PL PL15733767T patent/PL3164393T3/pl unknown
- 2015-07-06 WO PCT/EP2015/065294 patent/WO2016001441A1/fr not_active Ceased
- 2015-07-06 PL PL18187037.9T patent/PL3418273T3/pl unknown
- 2015-07-06 DK DK18187037.9T patent/DK3418273T3/da active
- 2015-07-06 DK DK15733767.6T patent/DK3164393T3/en active
- 2015-07-06 EP EP21213303.7A patent/EP3998257A1/fr active Pending
-
2017
- 2017-12-01 US US15/829,630 patent/US10519125B2/en active Active
-
2019
- 2019-12-20 JP JP2019230768A patent/JP6951406B2/ja active Active
-
2021
- 2021-09-22 JP JP2021154798A patent/JP7340574B2/ja active Active
-
2023
- 2023-08-25 JP JP2023137552A patent/JP2023159393A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| ES2908225T3 (es) | 2022-04-28 |
| JP6637954B2 (ja) | 2020-01-29 |
| JP2023159393A (ja) | 2023-10-31 |
| EP3418273B1 (fr) | 2022-01-12 |
| US10519125B2 (en) | 2019-12-31 |
| US20180086729A1 (en) | 2018-03-29 |
| WO2016001441A1 (fr) | 2016-01-07 |
| JP2022000455A (ja) | 2022-01-04 |
| JP6951406B2 (ja) | 2021-10-20 |
| EP3164393B1 (fr) | 2018-09-19 |
| PL3164393T3 (pl) | 2019-03-29 |
| ES2700156T3 (es) | 2019-02-14 |
| US10047064B2 (en) | 2018-08-14 |
| PL3418273T3 (pl) | 2022-08-01 |
| FR3023290A1 (fr) | 2016-01-08 |
| FR3023290B1 (fr) | 2016-08-19 |
| JP2020063289A (ja) | 2020-04-23 |
| JP7340574B2 (ja) | 2023-09-07 |
| EP3418273A1 (fr) | 2018-12-26 |
| DK3164393T3 (en) | 2019-01-21 |
| EP3164393A1 (fr) | 2017-05-10 |
| JP2017519796A (ja) | 2017-07-20 |
| US20170137400A1 (en) | 2017-05-18 |
| EP3998257A1 (fr) | 2022-05-18 |
| TR201819805T4 (tr) | 2019-01-21 |
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