DK3209686T3 - Monoklonale anti-gpc-1-antistoffer og anvendelser deraf - Google Patents

Monoklonale anti-gpc-1-antistoffer og anvendelser deraf Download PDF

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Publication number
DK3209686T3
DK3209686T3 DK14904438.0T DK14904438T DK3209686T3 DK 3209686 T3 DK3209686 T3 DK 3209686T3 DK 14904438 T DK14904438 T DK 14904438T DK 3209686 T3 DK3209686 T3 DK 3209686T3
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Denmark
Prior art keywords
gpc
antibodies
applications
monoclonal anti
monoclonal
Prior art date
Application number
DK14904438.0T
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English (en)
Inventor
Fuenmayor Irene Justiniano
Aline Nocon
Julie Soon
Quach Truong
Sandra Wissmueller
Douglas Campbell
Bradley Walsh
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Glyp Holdings Pty Ltd
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Publication of DK3209686T3 publication Critical patent/DK3209686T3/da

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C07K16/3038Kidney, bladder
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/10Cells modified by introduction of foreign genetic material
    • C12N5/12Fused cells, e.g. hybridomas
    • C12N5/16Animal cells
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/10Cells modified by introduction of foreign genetic material
    • C12N5/12Fused cells, e.g. hybridomas
    • C12N5/16Animal cells
    • C12N5/163Animal cells one of the fusion partners being a B or a T lymphocyte
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57407Specifically defined cancers
    • G01N33/57438Specifically defined cancers of liver, pancreas or kidney
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/10Immunoglobulins specific features characterized by their source of isolation or production
    • C07K2317/14Specific host cells or culture conditions, e.g. components, pH or temperature
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/52Constant or Fc region; Isotype
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/52Constant or Fc region; Isotype
    • C07K2317/53Hinge
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/54F(ab')2
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/55Fab or Fab'
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565Complementarity determining region [CDR]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/567Framework region [FR]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/60Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
    • C07K2317/62Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
    • C07K2317/622Single chain antibody (scFv)
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705Assays involving receptors, cell surface antigens or cell surface determinants

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Cell Biology (AREA)
  • Zoology (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Hematology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Oncology (AREA)
  • Hospice & Palliative Care (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DK14904438.0T 2014-10-23 2014-10-23 Monoklonale anti-gpc-1-antistoffer og anvendelser deraf DK3209686T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/AU2014/000999 WO2016061608A1 (en) 2014-10-23 2014-10-23 Monoclonal ανίί-gpc-l antibodies and uses thereof

Publications (1)

Publication Number Publication Date
DK3209686T3 true DK3209686T3 (da) 2020-03-16

Family

ID=55759935

Family Applications (1)

Application Number Title Priority Date Filing Date
DK14904438.0T DK3209686T3 (da) 2014-10-23 2014-10-23 Monoklonale anti-gpc-1-antistoffer og anvendelser deraf

Country Status (11)

Country Link
US (1) US10577418B2 (da)
EP (1) EP3209686B1 (da)
JP (1) JP6749901B2 (da)
KR (1) KR102249981B1 (da)
CN (1) CN107108734B (da)
AU (1) AU2014409558B2 (da)
CA (1) CA2964179C (da)
DK (1) DK3209686T3 (da)
ES (1) ES2778100T3 (da)
SG (1) SG11201703006QA (da)
WO (1) WO2016061608A1 (da)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG11201708624YA (en) * 2015-04-20 2017-11-29 Minomic Int Ltd Therapeutic antibodies and uses thereof
US20200308299A1 (en) * 2017-04-28 2020-10-01 National University Corporation Kochi University Anti-gpc-1 antibody
AU2020212534A1 (en) * 2019-01-22 2021-07-22 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services High affinity monoclonal antibodies targeting glypican-1 and methods of use
JP2020007315A (ja) * 2019-08-02 2020-01-16 ミノミック インターナショナル リミティド モノクローナル抗gpc−1抗体およびその使用
GB202212077D0 (en) 2022-08-18 2022-10-05 Tribune Therapeutics Ab Agents that inhibit ccn ligand-induced signalling for treating disease

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU642419B2 (en) 1989-05-24 1993-10-21 South Eastern Sydney Area Health Service Monoclonal antibodies which recognise malignant cells from bladder carcinomas
JPH05504466A (ja) * 1989-05-24 1993-07-15 ザ セントラル シドニー エリア ヘルス サービス 膀胱癌からの悪性細胞を認識するモノクローナル抗体
US5622836A (en) * 1989-05-24 1997-04-22 The University Of Sydney Monoclonal antibodies which recognize malignant cells from bladder carcinomas
US5622835A (en) 1994-04-28 1997-04-22 The Wistar Institute Of Anatomy & Biology WT1 monoclonal antibodies
CN101070345B (zh) * 2006-05-12 2010-09-29 中国科学院上海生命科学研究院 抗前列腺特异抗原psa单克隆抗体及应用
KR102366820B1 (ko) 2014-01-17 2022-02-22 미노믹 인터내셔널 리미티드 진단을 위한 세포 표면 전립선암 항원
DK3245219T3 (da) 2015-01-16 2020-06-29 Glyp Holdings Pty Ltd Glypicanepitoper og anvendelser deraf
SG11201708624YA (en) 2015-04-20 2017-11-29 Minomic Int Ltd Therapeutic antibodies and uses thereof

Also Published As

Publication number Publication date
WO2016061608A8 (en) 2017-06-29
SG11201703006QA (en) 2017-05-30
EP3209686A4 (en) 2018-03-07
KR20170085051A (ko) 2017-07-21
KR102249981B1 (ko) 2021-05-11
AU2014409558B2 (en) 2021-08-12
AU2014409558A1 (en) 2017-05-04
CN107108734A (zh) 2017-08-29
JP2017531442A (ja) 2017-10-26
US20180072803A1 (en) 2018-03-15
ES2778100T3 (es) 2020-08-07
EP3209686B1 (en) 2019-12-25
JP6749901B2 (ja) 2020-09-02
EP3209686A1 (en) 2017-08-30
AU2014409558A8 (en) 2019-08-08
CN107108734B (zh) 2021-09-14
WO2016061608A1 (en) 2016-04-28
CA2964179A1 (en) 2016-04-28
CA2964179C (en) 2023-04-11
US10577418B2 (en) 2020-03-03

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