DK320287A - PROCEDURE FOR USING BARL FOR Separation of Alien Proteins - Google Patents
PROCEDURE FOR USING BARL FOR Separation of Alien ProteinsInfo
- Publication number
- DK320287A DK320287A DK320287A DK320287A DK320287A DK 320287 A DK320287 A DK 320287A DK 320287 A DK320287 A DK 320287A DK 320287 A DK320287 A DK 320287A DK 320287 A DK320287 A DK 320287A
- Authority
- DK
- Denmark
- Prior art keywords
- barl
- alien
- proteins
- separation
- procedure
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
- C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/62—Insulins
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
- C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
- C12N15/815—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts for yeasts other than Saccharomyces
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/58—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from fungi
- C12N9/60—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from fungi from yeast
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/10—Fusion polypeptide containing a localisation/targetting motif containing a tag for extracellular membrane crossing, e.g. TAT or VP22
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/50—Fusion polypeptide containing protease site
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
- C07K2319/74—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor
- C07K2319/75—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor containing a fusion for activation of a cell surface receptor, e.g. thrombopoeitin, NPY and other peptide hormones
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US79130585A | 1985-10-25 | 1985-10-25 | |
PCT/US1986/002198 WO1987002670A1 (en) | 1985-10-25 | 1986-10-20 | Method of using bar1 for secreting foreign proteins |
Publications (2)
Publication Number | Publication Date |
---|---|
DK320287A true DK320287A (en) | 1987-06-23 |
DK320287D0 DK320287D0 (en) | 1987-06-23 |
Family
ID=25153298
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK320287A DK320287D0 (en) | 1985-10-25 | 1987-06-23 | PROCEDURE FOR USING BARL FOR Separation of Alien Proteins |
Country Status (13)
Country | Link |
---|---|
EP (1) | EP0243465A1 (en) |
JP (1) | JP2523562B2 (en) |
CN (1) | CN1027179C (en) |
AU (2) | AU6543286A (en) |
CA (1) | CA1316133C (en) |
CZ (1) | CZ284251B6 (en) |
DK (1) | DK320287D0 (en) |
FI (1) | FI872801A0 (en) |
HU (1) | HU206897B (en) |
IE (1) | IE63822B1 (en) |
SK (1) | SK279041B6 (en) |
UA (1) | UA41863C2 (en) |
WO (1) | WO1987002670A1 (en) |
Families Citing this family (54)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DK58285D0 (en) * | 1984-05-30 | 1985-02-08 | Novo Industri As | PEPTIDES AND MANUFACTURING AND USING THEREOF |
EP0310137B1 (en) * | 1987-10-02 | 1994-01-26 | Zymogenetics, Inc. | BAR1 secretion signal |
US5206699A (en) * | 1988-05-06 | 1993-04-27 | Gersan Establishment | Sensing a narrow frequency band of radiation and gemstones |
AU633020B2 (en) * | 1988-07-23 | 1993-01-21 | Novozymes Delta Limited | New secretory leader sequences |
WO1991013971A1 (en) * | 1990-03-13 | 1991-09-19 | Hawaii Biotechnology Group, Inc. | Neurospora expression system |
DK82893D0 (en) * | 1993-07-08 | 1993-07-08 | Novo Nordisk As | PEPTIDE |
CN1182451A (en) | 1995-03-17 | 1998-05-20 | 诺沃挪第克公司 | Novel endoglucanases |
WO1997031943A1 (en) | 1996-03-01 | 1997-09-04 | Novo Nordisk A/S | Use of a pharmaceutical composition comprising an appetite-suppressing peptide |
ES2327606T3 (en) | 2000-01-10 | 2009-11-02 | Maxygen Holdings Ltd | CONJUGATES OF G-CSF. |
PL204285B1 (en) | 2000-02-11 | 2009-12-31 | Bayer Healthcare Llc | FACTOR VII OR VIIa−LIKE MOLECULES |
CA2469846A1 (en) | 2001-02-27 | 2002-09-26 | Maxygen Aps | New interferon beta-like molecules |
BR0208203A (en) | 2001-03-22 | 2005-04-19 | Novo Nordisk Healthcare Ag | Factor vii polypeptide, factor vii derivative, composition, pharmaceutical composition, polynucleotide construction, eukaryotic host cell, transgenic animal, transgenic plant, and methods for producing factor vii polypeptide and a factor vii derivative, use of a derivative of vii, methods for treating bleeding episodes or bleeding disorders in a patient or for enhancing the normal hemostatic system and inhibiting thrombus formation in a patient |
US6534059B2 (en) | 2001-06-05 | 2003-03-18 | Advanced Biotherapy, Inc. | Compositions and methods for treating hyperimmune response in the eye |
EP1432794B1 (en) | 2001-09-27 | 2011-11-09 | Novo Nordisk Health Care AG | Human coagulation factor vii polypeptides |
CN101870729A (en) | 2003-09-09 | 2010-10-27 | 诺和诺德医疗保健公司 | Coagulation factor vii polypeptides |
RU2412199C2 (en) | 2005-04-18 | 2011-02-20 | Ново Нордиск А/С | Versions of il-21 |
US9056921B2 (en) | 2005-08-16 | 2015-06-16 | Novo Nordisk A/S | Method for making mature insulin polypeptides |
WO2007031559A2 (en) | 2005-09-14 | 2007-03-22 | Novo Nordisk Health Care Ag | Human coagulation factor vii polypeptides |
EP2407561A3 (en) | 2006-03-06 | 2012-05-30 | Humagene, Inc. | A method for the preparation of recombinant human fibrinogen |
AU2007292903B2 (en) | 2006-09-08 | 2012-03-29 | Ambrx, Inc. | Modified human plasma polypeptide or Fc scaffolds and their uses |
WO2008037735A1 (en) | 2006-09-27 | 2008-04-03 | Novo Nordisk A/S | Method for making maturated insulin polypeptides |
NZ580686A (en) | 2007-05-02 | 2012-11-30 | Ambrx Inc | Modified interferon beta polypeptides and their uses |
CN101918026B (en) | 2007-11-20 | 2016-03-02 | Ambrx公司 | Modified insulin polypeptides and its purposes |
ES2654387T3 (en) | 2008-07-23 | 2018-02-13 | Ambrx, Inc. | Modified bovine G-CSF polypeptides and their uses |
US8349325B2 (en) | 2008-12-23 | 2013-01-08 | Abbott Laboratories | Soluble FMS-like tyrosine kinase-1 (sFLT-1) antibody and related composition, kit, methods of using, and materials and method for making |
US20120107267A1 (en) | 2009-03-11 | 2012-05-03 | Novo Nordisk A/S | Interleukin-21 variants having antagonistic binding to the il-21 receptor |
CN102712687A (en) | 2009-07-17 | 2012-10-03 | 丹麦国家医院 | MASP isoforms as inhibitors of complement activation |
WO2011067283A1 (en) | 2009-12-01 | 2011-06-09 | Novo Nordisk A/S | Novel peptidyl alpha-hydroxyglycine alpha-amidating lyases |
EA201290541A1 (en) | 2009-12-21 | 2013-05-30 | Амбркс, Инк. | MODIFIED BULL SOMATOTROPINE POLYPEPTIDES AND THEIR APPLICATION |
CA2784800A1 (en) | 2009-12-21 | 2011-07-21 | Ambrx, Inc. | Modified porcine somatotropin polypeptides and their uses |
EP3815708A1 (en) | 2010-03-05 | 2021-05-05 | Omeros Corporation | Chimeric inhibitor molecules of complement activation |
US20110229921A1 (en) | 2010-03-18 | 2011-09-22 | Abbott Laboratories | METHODS OF ASSAYING URINARY NEUTROPHIL GELATINASE-ASSOCIATED LIPOCALIN (uNGAL) IN THE PROGNOSIS OF CADAVERIC KIDNEY TRANSPLANT FUNCTION IN A PATIENT, INCLUDING A PATIENT DIAGNOSED WITH DELAYED GRAFT FUNCTION (DGF), A METHOD OF ASSAYING uNGAL IN THE ASSESSMENT OF RISK OF DGF IN A PATIENT DIAGNOSED WITH EARLY GRAFT FUNCTION (EGF), AND RELATED KITS |
WO2011163558A1 (en) | 2010-06-25 | 2011-12-29 | Abbott Laboratories | Materials and methods for assay of anti-hepatitis c virus (hcv) antibodies |
MA34521B1 (en) | 2010-08-17 | 2013-09-02 | Ambrx Inc | MODIFIED RELAXINE POLYPEPTIDES AND USES THEREOF |
AR083006A1 (en) | 2010-09-23 | 2013-01-23 | Lilly Co Eli | FORMULATIONS FOR THE STIMULATING FACTOR OF COLONIES OF GRANULOCITS (G-CSF) BOVINE AND VARIANTS OF THE SAME |
US20120115244A1 (en) | 2010-11-09 | 2012-05-10 | Abbott Laboratories | Materials and methods for immunoassay of pterins |
CN103476928B (en) | 2010-12-09 | 2017-03-29 | 巴斯德研究所 | For obtaining the method based on MGMT of high yield expression of recombinant proteins |
WO2013083847A2 (en) | 2011-12-09 | 2013-06-13 | Institut Pasteur | Multiplex immuno screening assay |
US8993248B2 (en) | 2011-12-31 | 2015-03-31 | Abbott Laboratories | Truncated human vitamin D binding protein and mutation and fusion thereof and related materials and methods of use |
PL2812024T3 (en) | 2012-02-09 | 2018-09-28 | Var2 Pharmaceuticals Aps | Targeting of chondroitin sulfate glycans |
WO2014060401A1 (en) | 2012-10-15 | 2014-04-24 | Novo Nordisk Health Care Ag | Coagulation factor vii polypeptides |
JP2014128262A (en) * | 2012-11-27 | 2014-07-10 | Kirin Brewery Co Ltd | Screening method for yeast strains having conjugative ability |
US20210108213A1 (en) | 2018-05-01 | 2021-04-15 | Ambrx, Inc. | A method for optimizing antibody expression |
US20210278406A1 (en) | 2018-07-13 | 2021-09-09 | Varct Diagnostic Aps | Isolation of circulating cells of fetal origin using recombinant malaria protein var2csa |
SG11202102427XA (en) | 2018-09-11 | 2021-04-29 | Ambrx Inc | Interleukin-2 polypeptide conjugates and their uses |
JP2022512746A (en) | 2018-10-19 | 2022-02-07 | アンブルックス,インコーポレイテッド | Interleukin-10 polypeptide complex, its dimer, and their use |
KR20210136014A (en) | 2019-02-12 | 2021-11-16 | 암브룩스, 인코포레이티드 | Compositions, methods and uses thereof containing antibody-TLR agonist conjugates |
IL296099A (en) | 2020-03-11 | 2022-11-01 | Ambrx Inc | Interleukin-2 polypeptide conjugates and methods of use thereof |
CA3175523A1 (en) | 2020-04-13 | 2021-10-21 | Antti Virtanen | Methods, complexes and kits for detecting or determining an amount of a .beta.-coronavirus antibody in a sample |
CA3188349A1 (en) | 2020-08-04 | 2022-02-10 | A. Scott Muerhoff | Improved methods and kits for detecting sars-cov-2 protein in a sample |
AU2021327396A1 (en) | 2020-08-20 | 2023-03-23 | Ambrx, Inc. | Antibody-TLR agonist conjugates, methods and uses thereof |
EP4271998A1 (en) | 2020-12-30 | 2023-11-08 | Abbott Laboratories | Methods for determining sars-cov-2 antigen and anti-sars-cov-2 antibody in a sample |
WO2022212899A1 (en) | 2021-04-03 | 2022-10-06 | Ambrx, Inc. | Anti-her2 antibody-drug conjugates and uses thereof |
CN115806889A (en) * | 2022-09-28 | 2023-03-17 | 山东大学 | Saccharomyces cerevisiae engineering bacterium capable of improving gene expression level and construction method and application thereof |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4546082A (en) * | 1982-06-17 | 1985-10-08 | Regents Of The Univ. Of California | E. coli/Saccharomyces cerevisiae plasmid cloning vector containing the alpha-factor gene for secretion and processing of hybrid proteins |
US4613572A (en) * | 1983-08-15 | 1986-09-23 | Kansas State University Research Foundation | Yeast BAR1 gene plasmid |
JPS61247384A (en) * | 1984-10-18 | 1986-11-04 | チモ−ジエネテイツクス インコ−ポレ−テツド | Development of plasminogen activating factor in yeast |
DE3537176C2 (en) * | 1984-10-18 | 1994-06-09 | Zymogenetics Inc | Tissue plasminogen activator and process for its manufacture |
-
1986
- 1986-10-20 HU HU865248A patent/HU206897B/en not_active IP Right Cessation
- 1986-10-20 UA UA4203156A patent/UA41863C2/en unknown
- 1986-10-20 WO PCT/US1986/002198 patent/WO1987002670A1/en active Application Filing
- 1986-10-20 EP EP86906638A patent/EP0243465A1/en not_active Withdrawn
- 1986-10-20 AU AU65432/86A patent/AU6543286A/en not_active Abandoned
- 1986-10-20 JP JP61505713A patent/JP2523562B2/en not_active Expired - Fee Related
- 1986-10-23 CA CA000521206A patent/CA1316133C/en not_active Expired - Fee Related
- 1986-10-23 IE IE280486A patent/IE63822B1/en not_active IP Right Cessation
- 1986-10-25 CN CN86107554A patent/CN1027179C/en not_active Expired - Lifetime
- 1986-10-27 SK SK7764-86A patent/SK279041B6/en unknown
- 1986-10-27 CZ CS867764A patent/CZ284251B6/en not_active IP Right Cessation
-
1987
- 1987-06-23 DK DK320287A patent/DK320287D0/en not_active Application Discontinuation
- 1987-06-24 FI FI872801A patent/FI872801A0/en not_active Application Discontinuation
-
1991
- 1991-04-02 AU AU74003/91A patent/AU676132B2/en not_active Ceased
Also Published As
Publication number | Publication date |
---|---|
HU206897B (en) | 1993-01-28 |
FI872801A (en) | 1987-06-24 |
EP0243465A1 (en) | 1987-11-04 |
IE862804L (en) | 1987-04-25 |
UA41863C2 (en) | 2001-10-15 |
CN86107554A (en) | 1987-08-26 |
DK320287D0 (en) | 1987-06-23 |
CZ776486A3 (en) | 1996-09-11 |
JPS63501614A (en) | 1988-06-23 |
AU6543286A (en) | 1987-05-19 |
IE63822B1 (en) | 1995-06-14 |
AU676132B2 (en) | 1997-03-06 |
SK776486A3 (en) | 1998-06-03 |
FI872801A0 (en) | 1987-06-24 |
CN1027179C (en) | 1994-12-28 |
WO1987002670A1 (en) | 1987-05-07 |
JP2523562B2 (en) | 1996-08-14 |
CA1316133C (en) | 1993-04-13 |
CZ284251B6 (en) | 1998-10-14 |
HUT43624A (en) | 1987-11-30 |
AU7400391A (en) | 1991-07-18 |
SK279041B6 (en) | 1998-06-03 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
AHS | Application shelved for other reasons than non-payment |