DK320287A - PROCEDURE FOR USING BARL FOR Separation of Alien Proteins - Google Patents

PROCEDURE FOR USING BARL FOR Separation of Alien Proteins

Info

Publication number
DK320287A
DK320287A DK320287A DK320287A DK320287A DK 320287 A DK320287 A DK 320287A DK 320287 A DK320287 A DK 320287A DK 320287 A DK320287 A DK 320287A DK 320287 A DK320287 A DK 320287A
Authority
DK
Denmark
Prior art keywords
barl
alien
proteins
separation
procedure
Prior art date
Application number
DK320287A
Other languages
Danish (da)
Other versions
DK320287D0 (en
Inventor
Vivian L Mackay
Original Assignee
Vivian L Mackay
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vivian L Mackay filed Critical Vivian L Mackay
Publication of DK320287A publication Critical patent/DK320287A/en
Publication of DK320287D0 publication Critical patent/DK320287D0/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C12N15/81Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • C07K14/62Insulins
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C12N15/81Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
    • C12N15/815Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts for yeasts other than Saccharomyces
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/48Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/58Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from fungi
    • C12N9/60Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from fungi from yeast
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/01Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/01Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/10Fusion polypeptide containing a localisation/targetting motif containing a tag for extracellular membrane crossing, e.g. TAT or VP22
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/50Fusion polypeptide containing protease site
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/70Fusion polypeptide containing domain for protein-protein interaction
    • C07K2319/74Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor
    • C07K2319/75Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor containing a fusion for activation of a cell surface receptor, e.g. thrombopoeitin, NPY and other peptide hormones
DK320287A 1985-10-25 1987-06-23 PROCEDURE FOR USING BARL FOR Separation of Alien Proteins DK320287D0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US79130585A 1985-10-25 1985-10-25
PCT/US1986/002198 WO1987002670A1 (en) 1985-10-25 1986-10-20 Method of using bar1 for secreting foreign proteins

Publications (2)

Publication Number Publication Date
DK320287A true DK320287A (en) 1987-06-23
DK320287D0 DK320287D0 (en) 1987-06-23

Family

ID=25153298

Family Applications (1)

Application Number Title Priority Date Filing Date
DK320287A DK320287D0 (en) 1985-10-25 1987-06-23 PROCEDURE FOR USING BARL FOR Separation of Alien Proteins

Country Status (13)

Country Link
EP (1) EP0243465A1 (en)
JP (1) JP2523562B2 (en)
CN (1) CN1027179C (en)
AU (2) AU6543286A (en)
CA (1) CA1316133C (en)
CZ (1) CZ284251B6 (en)
DK (1) DK320287D0 (en)
FI (1) FI872801A0 (en)
HU (1) HU206897B (en)
IE (1) IE63822B1 (en)
SK (1) SK279041B6 (en)
UA (1) UA41863C2 (en)
WO (1) WO1987002670A1 (en)

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EP0310137B1 (en) * 1987-10-02 1994-01-26 Zymogenetics, Inc. BAR1 secretion signal
US5206699A (en) * 1988-05-06 1993-04-27 Gersan Establishment Sensing a narrow frequency band of radiation and gemstones
AU633020B2 (en) * 1988-07-23 1993-01-21 Novozymes Delta Limited New secretory leader sequences
WO1991013971A1 (en) * 1990-03-13 1991-09-19 Hawaii Biotechnology Group, Inc. Neurospora expression system
DK82893D0 (en) * 1993-07-08 1993-07-08 Novo Nordisk As PEPTIDE
CN1182451A (en) 1995-03-17 1998-05-20 诺沃挪第克公司 Novel endoglucanases
WO1997031943A1 (en) 1996-03-01 1997-09-04 Novo Nordisk A/S Use of a pharmaceutical composition comprising an appetite-suppressing peptide
ES2327606T3 (en) 2000-01-10 2009-11-02 Maxygen Holdings Ltd CONJUGATES OF G-CSF.
PL204285B1 (en) 2000-02-11 2009-12-31 Bayer Healthcare Llc FACTOR VII OR VIIa−LIKE MOLECULES
CA2469846A1 (en) 2001-02-27 2002-09-26 Maxygen Aps New interferon beta-like molecules
BR0208203A (en) 2001-03-22 2005-04-19 Novo Nordisk Healthcare Ag Factor vii polypeptide, factor vii derivative, composition, pharmaceutical composition, polynucleotide construction, eukaryotic host cell, transgenic animal, transgenic plant, and methods for producing factor vii polypeptide and a factor vii derivative, use of a derivative of vii, methods for treating bleeding episodes or bleeding disorders in a patient or for enhancing the normal hemostatic system and inhibiting thrombus formation in a patient
US6534059B2 (en) 2001-06-05 2003-03-18 Advanced Biotherapy, Inc. Compositions and methods for treating hyperimmune response in the eye
EP1432794B1 (en) 2001-09-27 2011-11-09 Novo Nordisk Health Care AG Human coagulation factor vii polypeptides
CN101870729A (en) 2003-09-09 2010-10-27 诺和诺德医疗保健公司 Coagulation factor vii polypeptides
RU2412199C2 (en) 2005-04-18 2011-02-20 Ново Нордиск А/С Versions of il-21
US9056921B2 (en) 2005-08-16 2015-06-16 Novo Nordisk A/S Method for making mature insulin polypeptides
WO2007031559A2 (en) 2005-09-14 2007-03-22 Novo Nordisk Health Care Ag Human coagulation factor vii polypeptides
EP2407561A3 (en) 2006-03-06 2012-05-30 Humagene, Inc. A method for the preparation of recombinant human fibrinogen
AU2007292903B2 (en) 2006-09-08 2012-03-29 Ambrx, Inc. Modified human plasma polypeptide or Fc scaffolds and their uses
WO2008037735A1 (en) 2006-09-27 2008-04-03 Novo Nordisk A/S Method for making maturated insulin polypeptides
NZ580686A (en) 2007-05-02 2012-11-30 Ambrx Inc Modified interferon beta polypeptides and their uses
CN101918026B (en) 2007-11-20 2016-03-02 Ambrx公司 Modified insulin polypeptides and its purposes
ES2654387T3 (en) 2008-07-23 2018-02-13 Ambrx, Inc. Modified bovine G-CSF polypeptides and their uses
US8349325B2 (en) 2008-12-23 2013-01-08 Abbott Laboratories Soluble FMS-like tyrosine kinase-1 (sFLT-1) antibody and related composition, kit, methods of using, and materials and method for making
US20120107267A1 (en) 2009-03-11 2012-05-03 Novo Nordisk A/S Interleukin-21 variants having antagonistic binding to the il-21 receptor
CN102712687A (en) 2009-07-17 2012-10-03 丹麦国家医院 MASP isoforms as inhibitors of complement activation
WO2011067283A1 (en) 2009-12-01 2011-06-09 Novo Nordisk A/S Novel peptidyl alpha-hydroxyglycine alpha-amidating lyases
EA201290541A1 (en) 2009-12-21 2013-05-30 Амбркс, Инк. MODIFIED BULL SOMATOTROPINE POLYPEPTIDES AND THEIR APPLICATION
CA2784800A1 (en) 2009-12-21 2011-07-21 Ambrx, Inc. Modified porcine somatotropin polypeptides and their uses
EP3815708A1 (en) 2010-03-05 2021-05-05 Omeros Corporation Chimeric inhibitor molecules of complement activation
US20110229921A1 (en) 2010-03-18 2011-09-22 Abbott Laboratories METHODS OF ASSAYING URINARY NEUTROPHIL GELATINASE-ASSOCIATED LIPOCALIN (uNGAL) IN THE PROGNOSIS OF CADAVERIC KIDNEY TRANSPLANT FUNCTION IN A PATIENT, INCLUDING A PATIENT DIAGNOSED WITH DELAYED GRAFT FUNCTION (DGF), A METHOD OF ASSAYING uNGAL IN THE ASSESSMENT OF RISK OF DGF IN A PATIENT DIAGNOSED WITH EARLY GRAFT FUNCTION (EGF), AND RELATED KITS
WO2011163558A1 (en) 2010-06-25 2011-12-29 Abbott Laboratories Materials and methods for assay of anti-hepatitis c virus (hcv) antibodies
MA34521B1 (en) 2010-08-17 2013-09-02 Ambrx Inc MODIFIED RELAXINE POLYPEPTIDES AND USES THEREOF
AR083006A1 (en) 2010-09-23 2013-01-23 Lilly Co Eli FORMULATIONS FOR THE STIMULATING FACTOR OF COLONIES OF GRANULOCITS (G-CSF) BOVINE AND VARIANTS OF THE SAME
US20120115244A1 (en) 2010-11-09 2012-05-10 Abbott Laboratories Materials and methods for immunoassay of pterins
CN103476928B (en) 2010-12-09 2017-03-29 巴斯德研究所 For obtaining the method based on MGMT of high yield expression of recombinant proteins
WO2013083847A2 (en) 2011-12-09 2013-06-13 Institut Pasteur Multiplex immuno screening assay
US8993248B2 (en) 2011-12-31 2015-03-31 Abbott Laboratories Truncated human vitamin D binding protein and mutation and fusion thereof and related materials and methods of use
PL2812024T3 (en) 2012-02-09 2018-09-28 Var2 Pharmaceuticals Aps Targeting of chondroitin sulfate glycans
WO2014060401A1 (en) 2012-10-15 2014-04-24 Novo Nordisk Health Care Ag Coagulation factor vii polypeptides
JP2014128262A (en) * 2012-11-27 2014-07-10 Kirin Brewery Co Ltd Screening method for yeast strains having conjugative ability
US20210108213A1 (en) 2018-05-01 2021-04-15 Ambrx, Inc. A method for optimizing antibody expression
US20210278406A1 (en) 2018-07-13 2021-09-09 Varct Diagnostic Aps Isolation of circulating cells of fetal origin using recombinant malaria protein var2csa
SG11202102427XA (en) 2018-09-11 2021-04-29 Ambrx Inc Interleukin-2 polypeptide conjugates and their uses
JP2022512746A (en) 2018-10-19 2022-02-07 アンブルックス,インコーポレイテッド Interleukin-10 polypeptide complex, its dimer, and their use
KR20210136014A (en) 2019-02-12 2021-11-16 암브룩스, 인코포레이티드 Compositions, methods and uses thereof containing antibody-TLR agonist conjugates
IL296099A (en) 2020-03-11 2022-11-01 Ambrx Inc Interleukin-2 polypeptide conjugates and methods of use thereof
CA3175523A1 (en) 2020-04-13 2021-10-21 Antti Virtanen Methods, complexes and kits for detecting or determining an amount of a .beta.-coronavirus antibody in a sample
CA3188349A1 (en) 2020-08-04 2022-02-10 A. Scott Muerhoff Improved methods and kits for detecting sars-cov-2 protein in a sample
AU2021327396A1 (en) 2020-08-20 2023-03-23 Ambrx, Inc. Antibody-TLR agonist conjugates, methods and uses thereof
EP4271998A1 (en) 2020-12-30 2023-11-08 Abbott Laboratories Methods for determining sars-cov-2 antigen and anti-sars-cov-2 antibody in a sample
WO2022212899A1 (en) 2021-04-03 2022-10-06 Ambrx, Inc. Anti-her2 antibody-drug conjugates and uses thereof
CN115806889A (en) * 2022-09-28 2023-03-17 山东大学 Saccharomyces cerevisiae engineering bacterium capable of improving gene expression level and construction method and application thereof

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* Cited by examiner, † Cited by third party
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US4546082A (en) * 1982-06-17 1985-10-08 Regents Of The Univ. Of California E. coli/Saccharomyces cerevisiae plasmid cloning vector containing the alpha-factor gene for secretion and processing of hybrid proteins
US4613572A (en) * 1983-08-15 1986-09-23 Kansas State University Research Foundation Yeast BAR1 gene plasmid
JPS61247384A (en) * 1984-10-18 1986-11-04 チモ−ジエネテイツクス インコ−ポレ−テツド Development of plasminogen activating factor in yeast
DE3537176C2 (en) * 1984-10-18 1994-06-09 Zymogenetics Inc Tissue plasminogen activator and process for its manufacture

Also Published As

Publication number Publication date
HU206897B (en) 1993-01-28
FI872801A (en) 1987-06-24
EP0243465A1 (en) 1987-11-04
IE862804L (en) 1987-04-25
UA41863C2 (en) 2001-10-15
CN86107554A (en) 1987-08-26
DK320287D0 (en) 1987-06-23
CZ776486A3 (en) 1996-09-11
JPS63501614A (en) 1988-06-23
AU6543286A (en) 1987-05-19
IE63822B1 (en) 1995-06-14
AU676132B2 (en) 1997-03-06
SK776486A3 (en) 1998-06-03
FI872801A0 (en) 1987-06-24
CN1027179C (en) 1994-12-28
WO1987002670A1 (en) 1987-05-07
JP2523562B2 (en) 1996-08-14
CA1316133C (en) 1993-04-13
CZ284251B6 (en) 1998-10-14
HUT43624A (en) 1987-11-30
AU7400391A (en) 1991-07-18
SK279041B6 (en) 1998-06-03

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