DK319785A - Acetyleniske phenoxypropanolderivater - Google Patents

Acetyleniske phenoxypropanolderivater Download PDF

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Publication number
DK319785A
DK319785A DK319785A DK319785A DK319785A DK 319785 A DK319785 A DK 319785A DK 319785 A DK319785 A DK 319785A DK 319785 A DK319785 A DK 319785A DK 319785 A DK319785 A DK 319785A
Authority
DK
Denmark
Prior art keywords
derivatives
acetylenic
phenoxypropanole
hypertensives
man
Prior art date
Application number
DK319785A
Other languages
Danish (da)
English (en)
Other versions
DK319785D0 (da
Inventor
John Robert Carson
Original Assignee
Mcneilab Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mcneilab Inc filed Critical Mcneilab Inc
Publication of DK319785D0 publication Critical patent/DK319785D0/da
Publication of DK319785A publication Critical patent/DK319785A/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00Preparation of carboxylic acid amides
    • C07C231/14Preparation of carboxylic acid amides by formation of carboxamide groups together with reactions not involving the carboxamide groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00Carboxylic acid amides
    • C07C233/01Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/02Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having nitrogen atoms of carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals
    • C07C233/04Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having nitrogen atoms of carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals with carbon atoms of carboxamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
    • C07C233/07Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having nitrogen atoms of carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals with carbon atoms of carboxamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a six-membered aromatic ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C17/00Preparation of halogenated hydrocarbons
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00Preparation of carboxylic acid amides
    • C07C231/22Separation; Purification; Stabilisation; Use of additives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C33/00Unsaturated compounds having hydroxy or O-metal groups bound to acyclic carbon atoms
    • C07C33/40Halogenated unsaturated alcohols
    • C07C33/46Halogenated unsaturated alcohols containing only six-membered aromatic rings as cyclic parts
    • C07C33/48Halogenated unsaturated alcohols containing only six-membered aromatic rings as cyclic parts with unsaturation outside the aromatic rings
    • C07C33/483Monocyclic
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D301/00Preparation of oxiranes
    • C07D301/27Condensation of epihalohydrins or halohydrins with compounds containing active hydrogen atoms
    • C07D301/28Condensation of epihalohydrins or halohydrins with compounds containing active hydrogen atoms by reaction with hydroxyl radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D301/00Preparation of oxiranes
    • C07D301/36Use of additives, e.g. for stabilisation
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D303/00Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02Compounds containing oxirane rings
    • C07D303/12Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
    • C07D303/18Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by etherified hydroxyl radicals
    • C07D303/28Ethers with hydroxy compounds containing oxirane rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
DK319785A 1984-07-13 1985-07-12 Acetyleniske phenoxypropanolderivater DK319785A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/630,796 US4652584A (en) 1984-07-13 1984-07-13 Acetylenic phenoxypropanol derivatives and pharmaceutical compositions for the treatment of hypertension

Publications (2)

Publication Number Publication Date
DK319785D0 DK319785D0 (da) 1985-07-12
DK319785A true DK319785A (da) 1986-01-14

Family

ID=24528600

Family Applications (1)

Application Number Title Priority Date Filing Date
DK319785A DK319785A (da) 1984-07-13 1985-07-12 Acetyleniske phenoxypropanolderivater

Country Status (14)

Country Link
US (1) US4652584A (es)
EP (1) EP0171209B1 (es)
KR (1) KR860001050A (es)
AT (1) ATE40987T1 (es)
AU (1) AU580079B2 (es)
CA (1) CA1248135A (es)
DE (1) DE3568424D1 (es)
DK (1) DK319785A (es)
ES (1) ES8609211A1 (es)
FI (1) FI852743L (es)
HU (1) HUT39147A (es)
NO (1) NO852814L (es)
NZ (1) NZ212614A (es)
ZA (1) ZA855288B (es)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5250546A (en) * 1984-09-28 1993-10-05 Nippon Chemiphar Co., Ltd. Amino-alcohol derivatives and processes for their preparation
US4663334A (en) * 1985-12-11 1987-05-05 Mcneilab, Inc. Heteroaromatic acetylenes useful as antihypertensive agents
US4772755A (en) * 1987-03-19 1988-09-20 Mcneilab, Inc. 1,2-1,4 addition reaction sequence leading to disubstituted acelylenes
DE4210332C1 (es) * 1992-03-30 1993-07-15 Gruenenthal Gmbh, 5100 Aachen, De
TW275614B (es) * 1993-02-15 1996-05-11 Senju Pharma Co
WO1995030764A1 (en) * 1994-05-10 1995-11-16 Bio-Technical Resources Lp Formation of and dehydraton of hydroxylated diphenylacetylenes
WO2004009531A1 (en) * 2002-07-24 2004-01-29 Janssen Pharmaceutica N.V. Acetylenic compounds useful in treating inflammatory disorders
US7022703B2 (en) * 2003-07-24 2006-04-04 Janssen Pharmaceutica, N.V. Acetylenic compound useful in treating inflammatory disorders
KR102251850B1 (ko) * 2019-05-22 2021-05-12 울산과학기술원 전기분해를 위한 촉매 코팅 전극, 촉매 페이스트 조성물 및 그들의 제조방법

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL6600177A (es) * 1966-01-07 1967-07-10
US4010158A (en) * 1967-05-18 1977-03-01 Boehringer Ingelheim Gmbh 1-(2'-Ethynyl-phenoxy)-2-hydroxy-3-butylamino-propanes and salts
IE32354B1 (en) * 1967-05-18 1973-07-11 Boehringer Sohn Ingelheim Propanolamine derivatives
US3914432A (en) * 1967-12-13 1975-10-21 Boehringer Sohn Ingelheim Pharmaceutical compositions containing a 1-(cyano-phenoxy)-2-hydroxy-3-alkylamino-propane and method of use
DE1643262C3 (de) * 1967-12-13 1975-06-26 C.H. Boehringer Sohn, 6507 Ingelheim i-Phenoxy^-hydroxy-S-alklyaminopropane, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
US3959338A (en) * 1970-10-05 1976-05-25 Boehringer Ingelheim Gmbh 1-(Cyano-phenoxy)-2-hydroxy-3-hydroxyalkylamino-propanes and salts thereof
DE2048838A1 (de) * 1970-10-05 1972-04-06 C H Boehnnger Sohn, 6507 Ingel heim Neue 1 Phenoxy 2 hydroxy 3 hydroxyal kylaminopropane und Verfahren zu ihrer Her stellung
DE2503222A1 (de) * 1975-01-27 1976-07-29 Boehringer Sohn Ingelheim Verfahren zur herstellung von 1-aryl- oxy-3-n-substituierten aminopropanderivaten
EP0041476B1 (de) * 1980-05-31 1985-07-24 Ciba-Geigy Ag Neue Aryl-Phenyl-Acetylen-Verbindungen

Also Published As

Publication number Publication date
DK319785D0 (da) 1985-07-12
KR860001050A (ko) 1986-02-22
ATE40987T1 (de) 1989-03-15
ES545004A0 (es) 1986-09-01
EP0171209B1 (en) 1989-03-01
ES8609211A1 (es) 1986-09-01
FI852743A0 (fi) 1985-07-11
EP0171209A1 (en) 1986-02-12
ZA855288B (en) 1987-02-25
AU580079B2 (en) 1988-12-22
DE3568424D1 (en) 1989-04-06
CA1248135A (en) 1989-01-03
FI852743L (fi) 1986-01-14
US4652584A (en) 1987-03-24
HUT39147A (en) 1986-08-28
AU4487185A (en) 1986-01-16
NZ212614A (en) 1989-01-06
NO852814L (no) 1986-01-14

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