DE3568424D1 - Acetylenic phenoxypropanol derivatives and pharmaceutical compositions for the treatment of hypertension - Google Patents
Acetylenic phenoxypropanol derivatives and pharmaceutical compositions for the treatment of hypertensionInfo
- Publication number
- DE3568424D1 DE3568424D1 DE8585304995T DE3568424T DE3568424D1 DE 3568424 D1 DE3568424 D1 DE 3568424D1 DE 8585304995 T DE8585304995 T DE 8585304995T DE 3568424 T DE3568424 T DE 3568424T DE 3568424 D1 DE3568424 D1 DE 3568424D1
- Authority
- DE
- Germany
- Prior art keywords
- pharmaceutical compositions
- acetylenic
- hypertension
- treatment
- phenoxypropanol
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C231/00—Preparation of carboxylic acid amides
- C07C231/14—Preparation of carboxylic acid amides by formation of carboxamide groups together with reactions not involving the carboxamide groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/02—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having nitrogen atoms of carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals
- C07C233/04—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having nitrogen atoms of carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals with carbon atoms of carboxamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
- C07C233/07—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having nitrogen atoms of carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals with carbon atoms of carboxamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C17/00—Preparation of halogenated hydrocarbons
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C231/00—Preparation of carboxylic acid amides
- C07C231/22—Separation; Purification; Stabilisation; Use of additives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C33/00—Unsaturated compounds having hydroxy or O-metal groups bound to acyclic carbon atoms
- C07C33/40—Halogenated unsaturated alcohols
- C07C33/46—Halogenated unsaturated alcohols containing only six-membered aromatic rings as cyclic parts
- C07C33/48—Halogenated unsaturated alcohols containing only six-membered aromatic rings as cyclic parts with unsaturation outside the aromatic rings
- C07C33/483—Monocyclic
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D301/00—Preparation of oxiranes
- C07D301/27—Condensation of epihalohydrins or halohydrins with compounds containing active hydrogen atoms
- C07D301/28—Condensation of epihalohydrins or halohydrins with compounds containing active hydrogen atoms by reaction with hydroxyl radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D301/00—Preparation of oxiranes
- C07D301/36—Use of additives, e.g. for stabilisation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
- C07D303/02—Compounds containing oxirane rings
- C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
- C07D303/18—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by etherified hydroxyl radicals
- C07D303/28—Ethers with hydroxy compounds containing oxirane rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/630,796 US4652584A (en) | 1984-07-13 | 1984-07-13 | Acetylenic phenoxypropanol derivatives and pharmaceutical compositions for the treatment of hypertension |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE3568424D1 true DE3568424D1 (en) | 1989-04-06 |
Family
ID=24528600
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE8585304995T Expired DE3568424D1 (en) | 1984-07-13 | 1985-07-12 | Acetylenic phenoxypropanol derivatives and pharmaceutical compositions for the treatment of hypertension |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US4652584A (de) |
| EP (1) | EP0171209B1 (de) |
| KR (1) | KR860001050A (de) |
| AT (1) | ATE40987T1 (de) |
| AU (1) | AU580079B2 (de) |
| CA (1) | CA1248135A (de) |
| DE (1) | DE3568424D1 (de) |
| DK (1) | DK319785A (de) |
| ES (1) | ES8609211A1 (de) |
| FI (1) | FI852743L (de) |
| HU (1) | HUT39147A (de) |
| NO (1) | NO852814L (de) |
| NZ (1) | NZ212614A (de) |
| ZA (1) | ZA855288B (de) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5250546A (en) * | 1984-09-28 | 1993-10-05 | Nippon Chemiphar Co., Ltd. | Amino-alcohol derivatives and processes for their preparation |
| US4663334A (en) * | 1985-12-11 | 1987-05-05 | Mcneilab, Inc. | Heteroaromatic acetylenes useful as antihypertensive agents |
| US4772755A (en) * | 1987-03-19 | 1988-09-20 | Mcneilab, Inc. | 1,2-1,4 addition reaction sequence leading to disubstituted acelylenes |
| DE4210332C1 (de) * | 1992-03-30 | 1993-07-15 | Gruenenthal Gmbh, 5100 Aachen, De | |
| TW275614B (de) * | 1993-02-15 | 1996-05-11 | Senju Pharma Co | |
| AU1845395A (en) * | 1994-05-10 | 1995-11-29 | Bio-Technical Resources Lp | Formation of and dehydraton of hydroxylated diphenylacetylenes |
| WO2004009531A1 (en) * | 2002-07-24 | 2004-01-29 | Janssen Pharmaceutica N.V. | Acetylenic compounds useful in treating inflammatory disorders |
| US7022703B2 (en) * | 2003-07-24 | 2006-04-04 | Janssen Pharmaceutica, N.V. | Acetylenic compound useful in treating inflammatory disorders |
| KR102251850B1 (ko) * | 2019-05-22 | 2021-05-12 | 울산과학기술원 | 전기분해를 위한 촉매 코팅 전극, 촉매 페이스트 조성물 및 그들의 제조방법 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL6600177A (de) * | 1966-01-07 | 1967-07-10 | ||
| US4010158A (en) * | 1967-05-18 | 1977-03-01 | Boehringer Ingelheim Gmbh | 1-(2'-Ethynyl-phenoxy)-2-hydroxy-3-butylamino-propanes and salts |
| IE32354B1 (en) * | 1967-05-18 | 1973-07-11 | Boehringer Sohn Ingelheim | Propanolamine derivatives |
| US3914432A (en) * | 1967-12-13 | 1975-10-21 | Boehringer Sohn Ingelheim | Pharmaceutical compositions containing a 1-(cyano-phenoxy)-2-hydroxy-3-alkylamino-propane and method of use |
| DE1643262C3 (de) * | 1967-12-13 | 1975-06-26 | C.H. Boehringer Sohn, 6507 Ingelheim | i-Phenoxy^-hydroxy-S-alklyaminopropane, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel |
| US3959338A (en) * | 1970-10-05 | 1976-05-25 | Boehringer Ingelheim Gmbh | 1-(Cyano-phenoxy)-2-hydroxy-3-hydroxyalkylamino-propanes and salts thereof |
| DE2048838A1 (de) * | 1970-10-05 | 1972-04-06 | C H Boehnnger Sohn, 6507 Ingel heim | Neue 1 Phenoxy 2 hydroxy 3 hydroxyal kylaminopropane und Verfahren zu ihrer Her stellung |
| DE2503222A1 (de) * | 1975-01-27 | 1976-07-29 | Boehringer Sohn Ingelheim | Verfahren zur herstellung von 1-aryl- oxy-3-n-substituierten aminopropanderivaten |
| US4412856A (en) * | 1980-05-31 | 1983-11-01 | Ciba-Geigy Corporation | Herbicidal heterocyclic and substituted phenyl phenylacetylene amines |
-
1984
- 1984-07-13 US US06/630,796 patent/US4652584A/en not_active Expired - Lifetime
-
1985
- 1985-06-21 CA CA000484756A patent/CA1248135A/en not_active Expired
- 1985-07-01 NZ NZ212614A patent/NZ212614A/xx unknown
- 1985-07-09 ES ES545004A patent/ES8609211A1/es not_active Expired
- 1985-07-11 FI FI852743A patent/FI852743L/fi not_active Application Discontinuation
- 1985-07-12 DK DK319785A patent/DK319785A/da not_active Application Discontinuation
- 1985-07-12 NO NO852814A patent/NO852814L/no unknown
- 1985-07-12 AU AU44871/85A patent/AU580079B2/en not_active Ceased
- 1985-07-12 HU HU852695A patent/HUT39147A/hu unknown
- 1985-07-12 AT AT85304995T patent/ATE40987T1/de active
- 1985-07-12 ZA ZA855288A patent/ZA855288B/xx unknown
- 1985-07-12 DE DE8585304995T patent/DE3568424D1/de not_active Expired
- 1985-07-12 EP EP85304995A patent/EP0171209B1/de not_active Expired
- 1985-07-12 KR KR1019850004981A patent/KR860001050A/ko not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| AU580079B2 (en) | 1988-12-22 |
| ATE40987T1 (de) | 1989-03-15 |
| DK319785A (da) | 1986-01-14 |
| EP0171209B1 (de) | 1989-03-01 |
| AU4487185A (en) | 1986-01-16 |
| EP0171209A1 (de) | 1986-02-12 |
| ES545004A0 (es) | 1986-09-01 |
| ZA855288B (en) | 1987-02-25 |
| NZ212614A (en) | 1989-01-06 |
| ES8609211A1 (es) | 1986-09-01 |
| FI852743A0 (fi) | 1985-07-11 |
| NO852814L (no) | 1986-01-14 |
| FI852743L (fi) | 1986-01-14 |
| CA1248135A (en) | 1989-01-03 |
| DK319785D0 (da) | 1985-07-12 |
| US4652584A (en) | 1987-03-24 |
| HUT39147A (en) | 1986-08-28 |
| KR860001050A (ko) | 1986-02-22 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition | ||
| 8339 | Ceased/non-payment of the annual fee |