DK3158975T3 - Protesesystem til hjerteklaperstatning - Google Patents

Protesesystem til hjerteklaperstatning Download PDF

Info

Publication number
DK3158975T3
DK3158975T3 DK16198837.3T DK16198837T DK3158975T3 DK 3158975 T3 DK3158975 T3 DK 3158975T3 DK 16198837 T DK16198837 T DK 16198837T DK 3158975 T3 DK3158975 T3 DK 3158975T3
Authority
DK
Denmark
Prior art keywords
heart valve
valve replacement
prosthetic system
prosthetic
replacement
Prior art date
Application number
DK16198837.3T
Other languages
English (en)
Inventor
Giovanni Righini
Sarah Zanon
Original Assignee
Innovheart S R L
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from IT000636A external-priority patent/ITBO20120636A1/it
Application filed by Innovheart S R L filed Critical Innovheart S R L
Application granted granted Critical
Publication of DK3158975T3 publication Critical patent/DK3158975T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/24—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
    • A61F2/2412—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body with soft flexible valve members, e.g. tissue valves shaped like natural valves
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/22—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for
    • A61B17/221—Gripping devices in the form of loops or baskets for gripping calculi or similar types of obstructions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/24—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
    • A61F2/2427—Devices for manipulating or deploying heart valves during implantation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/24—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
    • A61F2/2442—Annuloplasty rings or inserts for correcting the valve shape; Implants for improving the function of a native heart valve
    • A61F2/2445—Annuloplasty rings in direct contact with the valve annulus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/24—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
    • A61F2/2442—Annuloplasty rings or inserts for correcting the valve shape; Implants for improving the function of a native heart valve
    • A61F2/2454—Means for preventing inversion of the valve leaflets, e.g. chordae tendineae prostheses
    • A61F2/2457—Chordae tendineae prostheses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/24—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
    • A61F2/2442—Annuloplasty rings or inserts for correcting the valve shape; Implants for improving the function of a native heart valve
    • A61F2/2466—Delivery devices therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/00234—Surgical instruments, devices or methods, e.g. tourniquets for minimally invasive surgery
    • A61B2017/00238—Type of minimally invasive operation
    • A61B2017/00243—Type of minimally invasive operation cardiac
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/00234—Surgical instruments, devices or methods, e.g. tourniquets for minimally invasive surgery
    • A61B2017/00358—Snares for grasping
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B2017/00743—Type of operation; Specification of treatment sites
    • A61B2017/00778—Operations on blood vessels
    • A61B2017/00783—Valvuloplasty
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/22—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for
    • A61B17/22031—Gripping instruments, e.g. forceps, for removing or smashing calculi
    • A61B2017/22035—Gripping instruments, e.g. forceps, for removing or smashing calculi for retrieving or repositioning foreign objects
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2220/00—Fixations or connections for prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2220/0025—Connections or couplings between prosthetic parts, e.g. between modular parts; Connecting elements
    • A61F2220/0033—Connections or couplings between prosthetic parts, e.g. between modular parts; Connecting elements made by longitudinally pushing a protrusion into a complementary-shaped recess, e.g. held by friction fit
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2220/00—Fixations or connections for prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2220/0025—Connections or couplings between prosthetic parts, e.g. between modular parts; Connecting elements
    • A61F2220/0075—Connections or couplings between prosthetic parts, e.g. between modular parts; Connecting elements sutured, ligatured or stitched, retained or tied with a rope, string, thread, wire or cable
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2250/00—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2250/0058—Additional features; Implant or prostheses properties not otherwise provided for
    • A61F2250/006—Additional features; Implant or prostheses properties not otherwise provided for modular

Landscapes

  • Health & Medical Sciences (AREA)
  • Cardiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Vascular Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Transplantation (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Surgery (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Prostheses (AREA)
DK16198837.3T 2012-11-20 2013-11-19 Protesesystem til hjerteklaperstatning DK3158975T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT000636A ITBO20120636A1 (it) 2012-11-20 2012-11-20 Sistema protesico sostitutivo per valvola cardiaca
EP13812152.0A EP2922500B1 (en) 2012-11-20 2013-11-19 Prosthetic system for heart valve replacement

Publications (1)

Publication Number Publication Date
DK3158975T3 true DK3158975T3 (da) 2023-03-13

Family

ID=53547733

Family Applications (2)

Application Number Title Priority Date Filing Date
DK16198837.3T DK3158975T3 (da) 2012-11-20 2013-11-19 Protesesystem til hjerteklaperstatning
DK13812152.0T DK2922500T3 (da) 2012-11-20 2013-11-19 Protesesystem til hjerteklaperstatning

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK13812152.0T DK2922500T3 (da) 2012-11-20 2013-11-19 Protesesystem til hjerteklaperstatning

Country Status (9)

Country Link
EP (3) EP3158975B1 (da)
JP (2) JP6203859B2 (da)
KR (2) KR102280752B1 (da)
AU (2) AU2013349353B2 (da)
BR (1) BR112015011672B1 (da)
CA (2) CA3112256C (da)
DK (2) DK3158975T3 (da)
ES (2) ES2613761T3 (da)
PL (2) PL3158975T3 (da)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8579964B2 (en) 2010-05-05 2013-11-12 Neovasc Inc. Transcatheter mitral valve prosthesis
US9554897B2 (en) 2011-04-28 2017-01-31 Neovasc Tiara Inc. Methods and apparatus for engaging a valve prosthesis with tissue
US9308087B2 (en) 2011-04-28 2016-04-12 Neovasc Tiara Inc. Sequentially deployed transcatheter mitral valve prosthesis
US9345573B2 (en) 2012-05-30 2016-05-24 Neovasc Tiara Inc. Methods and apparatus for loading a prosthesis onto a delivery system
US9572665B2 (en) 2013-04-04 2017-02-21 Neovasc Tiara Inc. Methods and apparatus for delivering a prosthetic valve to a beating heart
KR20150026766A (ko) 2013-08-29 2015-03-11 김준홍 승모판막 서클라지 시술용 카테터 및 이를 이용한 유도방법
CN108601645B (zh) 2015-12-15 2021-02-26 内奥瓦斯克迪亚拉公司 经中隔递送系统
EP4183372A1 (en) 2016-01-29 2023-05-24 Neovasc Tiara Inc. Prosthetic valve for avoiding obstruction of outflow
EP3541462A4 (en) 2016-11-21 2020-06-17 Neovasc Tiara Inc. METHODS AND SYSTEMS FOR RAPID RETRACTION OF A TRANSCATHETER HEART VALVE DELIVERY SYSTEM
EP3600158B1 (en) * 2017-03-28 2024-04-17 Cardiac Success Ltd. Device for improving cardiac function
US10856984B2 (en) 2017-08-25 2020-12-08 Neovasc Tiara Inc. Sequentially deployed transcatheter mitral valve prosthesis
KR102167091B1 (ko) * 2018-08-21 2020-10-16 (주) 타우피엔유메디칼 스네어 일체형 심근 전기 신호 감지 카테터
AU2019374743B2 (en) 2018-11-08 2022-03-03 Neovasc Tiara Inc. Ventricular deployment of a transcatheter mitral valve prosthesis
CA3132873A1 (en) 2019-03-08 2020-09-17 Neovasc Tiara Inc. Retrievable prosthesis delivery system
CN113811265A (zh) 2019-04-01 2021-12-17 内奥瓦斯克迪亚拉公司 能够以可控的方式部署的假体瓣膜
AU2020271896B2 (en) 2019-04-10 2022-10-13 Neovasc Tiara Inc. Prosthetic valve with natural blood flow
WO2020236931A1 (en) 2019-05-20 2020-11-26 Neovasc Tiara Inc. Introducer with hemostasis mechanism
KR102207685B1 (ko) * 2019-05-31 2021-01-26 (주) 타우피엔유메디칼 히스 감지 스네어 카테터
WO2020257643A1 (en) 2019-06-20 2020-12-24 Neovasc Tiara Inc. Low profile prosthetic mitral valve
US11517425B2 (en) 2019-07-25 2022-12-06 Innovheart S.R.L. Device for implanting a prosthesis for a heart valve and assembly procedure
IT201900015494A1 (it) * 2019-09-03 2021-03-03 Innovheart S R L Dispositivo per la disposizione di fili guida attorno ad una valvola cardiaca
US11684473B2 (en) 2019-07-25 2023-06-27 Innovheart S.R.L. Device for arranging guidewires around a heart valve
DK4003234T5 (da) * 2019-07-25 2024-06-03 Innovheart S R L Indretning til at arrangere føringstråde omkring en hjerteklap
EP4132428A4 (en) * 2020-04-08 2024-05-01 Shifamed Holdings, LLC VALVE DISPENSING SYSTEM

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7927371B2 (en) * 2005-07-15 2011-04-19 The Cleveland Clinic Foundation Apparatus and method for reducing cardiac valve regurgitation
US8449605B2 (en) * 2006-06-28 2013-05-28 Kardium Inc. Method for anchoring a mitral valve
EP3854315A1 (en) 2007-10-19 2021-07-28 Ancora Heart, Inc. Systems for cardiac remodeling
US8287591B2 (en) * 2008-09-19 2012-10-16 Edwards Lifesciences Corporation Transformable annuloplasty ring configured to receive a percutaneous prosthetic heart valve implantation
EP4129238A1 (en) * 2010-03-05 2023-02-08 Edwards Lifesciences Corporation Retaining mechanisms for prosthetic valves
EP4241701B1 (en) * 2010-07-09 2024-09-18 Highlife SAS Transcatheter atrio-ventricular valve prosthesis
EP2600799B1 (en) * 2010-08-04 2017-05-17 ValCare, Inc. Percutaneous transcatheter repair of heart valves
IT1402571B1 (it) 2010-11-12 2013-09-13 Ht Consultant Di Giovanni Righini Sistema protesico per valvola cardio-vascolare con struttura di ancoraggio separata
CA3035048C (en) 2010-12-23 2021-05-04 Mark Deem System for mitral valve repair and replacement
US9039713B2 (en) * 2011-05-13 2015-05-26 Merit Medical Systems, Inc. Releasably attached snare loop retrieval device and method of using the same
AU2013221670A1 (en) * 2012-02-13 2014-10-02 Mitraspan, Inc Method and apparatus for repairing a mitral valve
CN104244841B (zh) * 2012-03-06 2017-08-29 海莱夫简易股份公司 具备环绕功能的医疗导管件

Also Published As

Publication number Publication date
EP2922500A1 (en) 2015-09-30
EP2922500B1 (en) 2016-11-16
CA3112256A1 (en) 2014-05-30
AU2018200730B2 (en) 2019-08-15
DK2922500T3 (da) 2017-02-06
JP6434589B2 (ja) 2018-12-05
CA2922899A1 (en) 2014-05-30
JP6203859B2 (ja) 2017-09-27
KR20200134337A (ko) 2020-12-01
AU2013349353A1 (en) 2015-07-09
KR102280752B1 (ko) 2021-07-22
CA2922899C (en) 2021-12-28
AU2018200730A1 (en) 2018-03-08
KR102232108B1 (ko) 2021-03-25
EP4147676A1 (en) 2023-03-15
BR112015011672B1 (pt) 2021-08-31
EP3158975A1 (en) 2017-04-26
PL2922500T3 (pl) 2017-05-31
PL3158975T3 (pl) 2023-05-02
ES2613761T3 (es) 2017-05-25
JP2017221747A (ja) 2017-12-21
CA3112256C (en) 2023-09-26
BR112015011672A2 (pt) 2017-07-11
KR20150091336A (ko) 2015-08-10
EP3158975B1 (en) 2023-01-04
ES2939616T3 (es) 2023-04-25
JP2016503320A (ja) 2016-02-04
AU2013349353B2 (en) 2017-11-09

Similar Documents

Publication Publication Date Title
DK3158975T3 (da) Protesesystem til hjerteklaperstatning
HK1248092B (zh) 用於人造心臟瓣膜的截平小葉
DK3593763T3 (da) Afgivelsessystemer til hjerteklapprotese
HK1215148A1 (zh) 幾何假體心臟瓣膜
IL235285B (en) Heart valve prosthesis
EP3572046C0 (en) HEART VALVE REPLACEMENT
BR112013019556A2 (pt) válvula cardíaca protética
EP2922592A4 (en) RETENTION MECHANISMS FOR PROSTHETIC CARDIAC VALVES
GB201205071D0 (en) Replacement heart valve
BR112013019558A2 (pt) válvula cardíaca protética.
DK2540256T3 (da) Prøvesystem til knæprotese
GB2517609B (en) Artificial heart system
EP2879618A4 (en) CARDIAC VALVULAR PROSTHESES
EP2856972A4 (en) ARTIFICIAL CARDIAC VALVE
EP2959866A4 (en) PROSTHETIC CARDIAC VALVE
DK2555710T3 (da) Transkateterafgivelsessystem til prostetisk hjerteventil med genindfangningsegenskab
LT2852354T (lt) Mitralinio vožtuvo protezas
PL2724690T3 (pl) Układ do instalowania protezy zastawki serca
DK2787926T3 (da) Forbedrede kommissurbærere til hjerteproteseklapper
EP2858711A4 (en) PROSTHETIC KIDNEY VALVE
FR2988154B1 (fr) Valve de distribution.
EP2677965A4 (en) PROSTHETIC CARDIAC VALVE
GB201211534D0 (en) Valve bridge
DK3669828T3 (da) Hjerteklapprotese
BR112014031355A2 (pt) prótese implantável de matriz extracelular